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See detailA pilot study of the safety and performance of the Otologics fully implantable hearing device: transducing sounds via the round window membrane to the inner ear.
Lefèbvre, Philippe ULg; Martin, Christine ULg; Dubreuil, C. et al

in Audiology & Neuro-otology (2009), 14(3), 172-80

OBJECTIVES: The safety and performance of the Otologics fully implantable hearing device were assessed in adult patients with mixed conductive and sensorineural hearing loss. METHODS: The subcutaneous ... [more ▼]

OBJECTIVES: The safety and performance of the Otologics fully implantable hearing device were assessed in adult patients with mixed conductive and sensorineural hearing loss. METHODS: The subcutaneous microphone of this fully implantable device picks up ambient sounds, converts them into an electrical signal, amplifies the signal according to the user's needs, and sends it to an electromechanical transducer. The transducer tip is customized with a prosthesis in order to be in contact with the round window membrane and is protected by fascia; this translates the electrical signal into a mechanical motion that directly stimulates the round window membrane and enables the user to perceive sound. The implanted battery is recharged daily via an external charger and the user can turn the implant on and off as well as adjust the volume with a hand-held remote control. In this pilot study, 6 patients with mixed conductive and sensorineural hearing loss were implanted with the Otologics fully implantable hearing device. Pre- and postoperative air conduction, bone conduction, as well as aided and unaided thresholds and speech scores were measured. RESULTS: No significant differences between preoperative and postoperative pure-tone averages were noted. Average improvement ranged from 19.16 to 35.8 dB of functional gain across audiometric frequencies with a mean of 26.17 +/- 5.15 dB. Long-term average functional gain at 12 months was 20.83 +/- 6.22 dB. Word recognition scores demonstrated significant differences between unaided and implant-aided conditions. CONCLUSIONS: Preliminary results of this trial of the Otologics fully implantable hearing device provide evidence that this fully implantable device is capable of efficiently transferring the sound to the inner ear via the round window membrane in patients with mixed hearing loss. [less ▲]

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See detailA pilot study on seborrheic dermatitis using pramiconazole as a potent oral anti-Malassezia agent.
Pierard, Gérald ULg; Ausma, Jannie; Henry, Frédérique ULg et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (2007), 214(2), 162-9

BACKGROUND: Seborrheic dermatitis is considered to be a Malassezia-driven disease. Little objective information is available so far from biometrological quantitative assessments of this skin condition ... [more ▼]

BACKGROUND: Seborrheic dermatitis is considered to be a Malassezia-driven disease. Little objective information is available so far from biometrological quantitative assessments of this skin condition. Pramiconazole is a novel triazole with potent in vitro antifungal activity, especially against Malassezia spp. OBJECTIVE: To study the sequential effects of pramiconazole on Malassezia, inflammation and epidermal changes. METHOD:This study was performed in 2 groups of subjects suffering from seborrheic dermatitis. The first group (n = 17) remained untreated and was used as control. Clinical, mycological and biometrological assessments were performed at inclusion and during the following 2 weeks. The second group of subjects (n = 10) received a single 200-mg oral dose of pramiconazole at inclusion. Clinical, mycological and biometrological evaluations were performed before and during 1 month following the single antifungal intake. For both parts of the study, several parameters were assessed including yeast density, desquamation, erythema, itching and sebum excretion. RESULTS: In the control group, no significant changes were observed in any of the parameters during the observation period. The findings were markedly different in the pramiconazole-treated subjects. The yeast density was significantly improved on days 3, 7 and 28. Desquamation, erythema, itching, and the global clinical evaluation as assessed by the patients and investigators became significantly improved on days 7 and 28. A trend in decrease of scaliness was noted. No effect on sebum excretion was evidenced. In conclusion, a single 200-mg dose of pramiconazole exhibitsin vivo efficacy in controlling some important clinical aspects of seborrheic dermatitis. Following a reduction in the number of yeasts on day 3, a decrease in the severity of clinical signs and symptoms occurred from day 7 onwards. Sebum excretion appeared uninvolved in the clearing process of seborrheic dermatitis. CONCLUSION: A single 200-mg dose of pramiconazole appears to abate seborrheic dermatitis. The density in Malassezia present on lesional skin is first decreased, followed by clearing of the clinical signs. [less ▲]

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See detailPilot trial of combined administration of erythropoietin and granulocyte colony-stimulating factor to children undergoing allogeneic bone marrow transplantation.
Locatelli, F.; Zecca, M.; Ponchio, L. et al

in Bone Marrow Transplantation (1994), 14(6), 929-35

We carried out a pilot study to evaluate the combined use of recombinant human erythropoietin (rhEpo) and granulocyte colony-stimulating factor (G-CSF) for accelerating marrow engraftment in children ... [more ▼]

We carried out a pilot study to evaluate the combined use of recombinant human erythropoietin (rhEpo) and granulocyte colony-stimulating factor (G-CSF) for accelerating marrow engraftment in children given allogeneic bone marrow transplantation (BMT). Fifteen consecutive children were enrolled in this study; 13 completed it and were evaluable. Using analysis of variance, laboratory and clinical data referring to these children were compared with those of 15 patients previously treated with rhEpo alone and with those of 16 historical controls. Erythroid repopulation, evaluated sequentially through serum transferrin receptor and reticulocyte count, was similarly accelerated in children receiving rhEpo alone and in those receiving combined treatment. These latter, however, showed a further reduction in the total number of red blood cell units required to reach transfusion independence (1.1 +/- 0.7 in the study population vs 2.7 +/- 1.2 in rhEpo group vs 4.2 +/- 2.3 in historical controls; values are mean +/- 1 SD; p < 0.001). Neutrophil engraftment, i.e. time for neutrophils to reach 0.5 x 10(9)/l, was 11 +/- 3 days in children receiving combined treatment, significantly shorter than that of the control groups (16 +/- 3 and 18 +/- 5, respectively; p < 0.001). Acceleration of neutrophil recovery translated into fewer infections: days of fever were significantly reduced in the study population (4 +/- 2 vs 11 +/- 8 vs 15 +/- 6, respectively).(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailPilot Trial of STAR in Medical ICU
Fisk, Liam M.; Le Compte, Aaron J.; Shaw, Geoffrey M. et al

Poster (2012, March)

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See detailPilot Trial of STAR in Medical ICU
Fisk, LM; Le Compte, A; Shaw, GM et al

in Critical Care (2012), 16 (Suppl 1)

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See detailPilot Trials of STAR Target to Range Glycemic Control
Penning, Sophie ULg; Le Compte, Aaron; Massion, Paul et al

Poster (2011)

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See detailPilot Trials of STAR Target to Range Glycemic Control
Penning, Sophie ULg; Le Compte, Aaron; Massion, Paul et al

in Intensive Care Medicine (2011), 37 (Suppl 1)

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See detailPilot Trials of the STAR TGC Protocol in a Cardiac Surgery ICU
LeCompte, Aaron J.; Penning, Sophie ULg; Moorhead, Katherine ULg et al

in Proceedings of the 10th Annual Diabetes Technology Meeting (2010, November)

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See detailLe pilotage de l'enseignement des sciences : un essai de synthèse...
Rousselet, S.; Monseur, Christian ULg

in Informations pédagogiques (1993), 9

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See detailLe pilotage de la performance dans les entreprises publiques : une approche par le "Tableau de bord équilibré" (BSC)
Van Caillie, Didier ULg

Conference given outside the academic context (2008)

This seminar discusses the principles of a performance monitoring approach based upon the Balanced ScoreCard Model and applied to public enterprises operating in the water industry.

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See detailLe pilotage des systèmes d'éducation
de Landsheere, Gilbert ULg

Book published by De Boek Université (1994)

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See detailLe pilotage des systèmes d'enseignement
de Landsheere, Gilbert ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (5-6), 115-120

Un peu moins de trois ans après le congrès 'La Wallonie au futur. Le défi de l'éducation' (Namur, octobre 1991), Gilbert de Landsheere reprend la parole lors de l'introduction d'une conférence-consensus ... [more ▼]

Un peu moins de trois ans après le congrès 'La Wallonie au futur. Le défi de l'éducation' (Namur, octobre 1991), Gilbert de Landsheere reprend la parole lors de l'introduction d'une conférence-consensus (Namur, mars 1994) sur le thème 'Où en est et où va le système éducatif en Wallonie? Comment le savoir ?'. Il y est plus inquiet et en colère que jamais... et il le fait savoir ! Il poursuit la réflexion qu'il avait livrée dans deux des textes que nous publions également dans ces Cahiers ('L'avenir de l'enseignement' et 'Propositions relatives à l'enseignement'). Il expose aussi la substance de l'ouvrage qu'il fera publié chez De Boeck la même année. [less ▲]

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See detailLe pilotage des systèmes scolaires
de Landsheere, Gilbert ULg

in Actes de la conférence-consensus ; La Wallonie au futur - Le défi de l’éducation ; Conférence-consensus : où en est et où va le système éducatif en Wallonie ? comment le savoir ? (1995)

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See detailLe pilotage du système éducatif via des indicateurs
Baye, Ariane ULg

Conference given outside the academic context (2004)

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See detailLe pilotage et la mesure de l’empreinte sociétale de l’entreprise grâce à la Balanced ScoreCard : entre adaptation et évolution radicale du modèle de Kaplan et Norton
Crutzen, Nathalie ULg; Van Caillie, Didier ULg

Conference (2007, November)

Vu l’intérêt croissant porté par les entreprises aux aspects sociaux et environnementaux, la présente communication propose une revue des principales contributions montrant l’importance et les enjeux de ... [more ▼]

Vu l’intérêt croissant porté par les entreprises aux aspects sociaux et environnementaux, la présente communication propose une revue des principales contributions montrant l’importance et les enjeux de la prise en compte des dimensions sociales et environnementales (de la RSE) dans les systèmes de contrôle de gestion des entreprises. Plus spécifiquement, face aux limites de nombreux outils pour piloter et mesurer adéquatement l’empreinte sociétale des entreprises, ce papier met en évidence les avantages présentés par la Balanced ScoreCard (BSC), un outil de contrôle de gestion développé par Kaplan et Norton (1992) et mondialement connu, pour prendre en compte ces nouvelles dimensions. Cette communication expose ensuite comment cet outil peut éventuellement être adapté afin de prendre en compte ces nouveaux impératifs (sociaux et environnementaux) dans le système de contrôle de gestion traditionnel de l’entreprise. Deux possibilités sont particulièrement envisagées : le découplage ou l’intégration des aspects sociétaux aux aspects traditionnels. Une analyse critique des principaux enseignements des recherches précédentes ainsi que des différentes possibilités d’adaptation de la BSC clôture finalement ce papier. [less ▲]

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See detailLe pilotage macro-budgétaire des finances locales
Husson, Jean-François ULg; Steckel, Marie-Christine

in Revue Européenne de l'Action Publique [=REAP] (2009), (1), 11

Ce bref article présente les justifications et modalités de mise en oeuvre du pilotage macro-budgétaire des finances locales, c.-à-d. de leur intégration dans le pilotage global du secteur des ... [more ▼]

Ce bref article présente les justifications et modalités de mise en oeuvre du pilotage macro-budgétaire des finances locales, c.-à-d. de leur intégration dans le pilotage global du secteur des administrations publiques tant en termes de solde de financement que de dette. [less ▲]

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