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See detailMacro Minitab pour l'analyse discriminante logistique
Palm, Rodolphe ULg

Software (2008)

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See detailMacro- and near-mesoporous monoliths by medium internal phase emulsion polymerization: a systematic study
Mathieu, Kevin ULg; Jérôme, Christine ULg; Debuigne, Antoine ULg

in Polymer (2016), 99

The synthesis of a series of poly(ethylene oxide)-b-polystyrene copolymers with different block lengths was performed by radical addition fragmentation chain transfer. These amphiphilic copolymers were ... [more ▼]

The synthesis of a series of poly(ethylene oxide)-b-polystyrene copolymers with different block lengths was performed by radical addition fragmentation chain transfer. These amphiphilic copolymers were tested as stabilizers for water-in-oil medium internal phase emulsion (MIPE) templating polymerization and the formation of polyMIPEs with controlled morphology. Aside from the structure of the emulsion stabilizer, several parameters susceptible to influence the size of the cavities and the interconnectivity of the porous monoliths were probed including the choice of the comonomers, treatment of the emulsion by ultrasound, the use of controlled radical polymerization method for the network formation as well as interfacial initiation. Interconnected cellular monoliths were produced. The polymerization of the ultrasonicated water-in-ethylhexylacrylate/divinylbenzene MIPE notably led to near-mesoporous open-cell material. Mechanical properties and specific surface areas of the polyMIPEs were also investigated and discussed. [less ▲]

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See detailMacro-economic factors influencing the architectural business model shift in the pharmaceutical industry
Dierks, Raphaela Marie Louisa ULg; Bruyère, Olivier ULg; Reginster, Jean-Yves ULg et al

in Expert Review of Pharmacoeconomics & Outcomes Research (2016), First online

Introduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its ... [more ▼]

Introduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its underlying business model. Despite significant articles in the press, there is little medical and economic evidence on the rationale driving the transformation from the traditional Research & Development (R&D) model to new alternative business models, such as Mergers & Acquisitions (M&A). The purpose of this review is to understand the macro-economic factors responsible for the revolution of the pharmaceutical business model, by understanding the needs, desires, new behavioral patterns, but also challenges within the industry. Considering these changes will be the key to possessing a competitive advantage over the market players. Areas covered: Existing literature on new macro-economic factors changing the pharmaceutical landscape has been reviewed to present a clear image of the current market environment. Expert commentary: Literature and media sources show that pharmaceutical companies are facing an architectural alteration in their business model, with more M&A deals and collaborations headlining the papers. Although Q1 2016 did show a major slowdown in M&A deals by volume since 2013 (with deal cancellations of Pfizer and Allergan, or the downfall of Valeant) pharmaceutical analysts remain confident that this shortfall was a consequence of the equity market volatility. It seems likely that the shift to an M&A model will become apparent during the remainder of 2016, with deal announcements such as Abbott Laboratories, AbbVie and Sanofi worth USD 45billion [1] showing the appetite of big pharma companies to shift from the fully vertical integrated business model to more horizontal business models. [less ▲]

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See detailA MACRO-ELEMENT FOR THE NONLINEAR ANALYSIS OF DEEP BEAMS BASED ON A THREE-PARAMETER KINEMATIC MODEL
Liu, Jian ULg; Mihaylov, Boyan ULg

Conference (2016, November 22)

This paper presents a computationally-effective macro element for predicting the complete shear response of RC deep beams. The element stems from a three-parameter kinematic theory (3PKT) for the shear ... [more ▼]

This paper presents a computationally-effective macro element for predicting the complete shear response of RC deep beams. The element stems from a three-parameter kinematic theory (3PKT) for the shear strength and deformation capacity of deep beams under double curvature. The macro element consists of two rotational springs and one transverse spring to simulate the nonlinear flexural and shear behaviour of deep shear spans. The element is applied to two deep beams tested to shear failure under three-point bending. The results are used to study the effect of unsymmetrical shear failures on the pre- and post-peak behaviour of nominally symmetrical members. It is found that the post-peak response is sensitive to the unloading path of the shear resisting mechanisms as well as to the global roughness of the critical diagonal cracks. Based on these analyses, modifications to the constitutive relationships of the shear mechanisms are proposed, and the macro element is applied to a continuous deep beam. It is shown that the model adequately captures the complete behaviour of the beam, including the redistribution of forces following the shear failure in the critical shear span. [less ▲]

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See detailA Macro-Element Formulation and Solution Procedure for Shear Analysis of RC Deep Beams
Liu, Jian ULg; Mihaylov, Boyan ULg

in the 11th fib International PhD Symposium in Civil Engineering (2016, August 30)

This paper presents a computationally-effective macro element capable of predicting the complete shear response of RC deep beams in analogy with beam elements for slender beams. The element stems from a ... [more ▼]

This paper presents a computationally-effective macro element capable of predicting the complete shear response of RC deep beams in analogy with beam elements for slender beams. The element stems from a three-parameter kinematic theory (3PKT) for the shear strength and deformation capacity of deep beams subjected to double curvature. The macro element is composed of two rotational springs and one transverse spring to simulate the nonlinear flexural and shear behaviour of the shear span. The element has two nodes (end sections) with two DOFs per node, which enables it to be easily connected to other elements of the same or different types to model structures with deep beams. The numerical implementation of the element is based on the secant stiffness approach which provides robust convergence properties. Validation studies are performed by using thirteen tests from the literature showing excellent results for the complete shear response. The obtained peak load experimental-to-predicted ratios have an average of 1.10 with a coefficient of variation of 14.2%, while these values for the mid-span deflection are 1.16 and 17.0%. [less ▲]

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See detailMacro-Kinematic Modelling of Continuous Deep Beams
Mihaylov, Boyan ULg

in Actes de la 14e édition des Journées Scientifiques, 22 et 23 août 2013, Université de Sherbrooke, Québec (2013, August 23)

Cet article présente une approche macro-cinématique permettant de décrire les schémas de déformation avec fissures diagonales des poutres-voile continues. On montre comment une poutre continue formée de ... [more ▼]

Cet article présente une approche macro-cinématique permettant de décrire les schémas de déformation avec fissures diagonales des poutres-voile continues. On montre comment une poutre continue formée de deux travées symétriques et supportant deux charges concentrées égales peut être modélisée à partir de seulement deux degrés de liberté. Ce modèle cinématique est combiné avec une théorie cinématique à trois paramètres (3PKT) qui permet de calculer la résistance au cisaillement de poutres-voile, les réactions d’appuis à la ruine et la capacité de déformation de poutres-voile continues. Cette approche a été appliquée à quatorze essais de cisaillement issus de la littérature avec différentes hauteurs de section, différents arrangement de l’armaturage longitudinal et différentes quantités d’armaturage de cisaillement. Les résultats montrent que cette approche macro-cinématique basée sur deux degrés de liberté reproduit correctement les tendances observées dans la capacité ultime au cisaillement des spécimens. [less ▲]

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See detailMacro-reimplantation de membre superieur. Mise au point et resultat fonctionnel a tres long-terme.
DATCO, Alexandru ULg; DUYSENS, Christophe ULg; MASSAGE, Patrick ULg et al

in Revue medicale de Liege (2013), 68(3), 122-7

Confronted with increasing problems of financing in health care, some question the relevance of certain interventions of high technicality. Today, the limiting factor for practitioners is not any longer ... [more ▼]

Confronted with increasing problems of financing in health care, some question the relevance of certain interventions of high technicality. Today, the limiting factor for practitioners is not any longer situated at the technical and technological level (the survival of macro replantations is assured in 85-90%) but moves slowly and surely towards the economic level. It is true that medicine has a price and that if a technique is expensive, it should at least be justified at the human level and superior to other less expensive therapeutic options which are available. In this article, we will first focus on the long-term outcome of patients and also on the functional benefit which brings them replantation compared to patients who underwent a regularization of their stump and possibly a reconstruction enabling them to be correctly fitted with a prosthesis. [less ▲]

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See detailMacro-scale variations of pCO2 distribution along the Belgium coast
Borges, Alberto ULg; Frankignoulle, M.

Conference (1997)

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See detailMacro-XRF scanning in archaeological and museum sites: pros and cons
Strivay, David ULg

Conference (2015, July 09)

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See detailMacroalgal community response to re-oligotrophication in Saronikos Gulf
Tsiamis, K.; Panayotidis, P.; Salomidi, M. et al

in Marine Ecology Progress Series (2013), 472

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See detailMacroarthropod-habitat relationships in oak forests in South Belgium. 1. Environments and communities
Branquart, E.; Kime, R. D.; Dufrêne, Marc ULg et al

in Pedobiologia (1995), 39(3), 243-263

[No abstract available]

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See detailLe macrobenthos de substrats meubles en zone infralittorale Corse - Indice et méthodologie adaptée pour un diagnostic écologique facilité
Donnay, Annick ULg

Doctoral thesis (2016)

At the time where the safeguarding and the conservation of the environment are a need for the Man, various ecological quality indicators are currently followed to evaluate the human influences; among ... [more ▼]

At the time where the safeguarding and the conservation of the environment are a need for the Man, various ecological quality indicators are currently followed to evaluate the human influences; among those the soft-bottom macrofauna. On the basis of some of their characteristics, the calculation of various biotic indices makes possible to qualify the meadow. However, before this qualification, the analysis of the macrobenthos is long and tedious. Two problems involved in their study exist: 1. In Corsica, the classically calculated biotic indices do not give an account of the existence of impacted settlements in oligotrophic coastal area and subjected to weak human influences. 2. The length of their study related to the difficulty of identification prevented a prompt response to the decision makers. To solve these problems, the adaptation of the calculation of a biotic index to the Corsican environmental conditions as well as the means of limiting the length of studies of the soft-bottom macrobenthos is required. For the adaptation of an index and to give an account of the natural variability of the settlements, eight habitats linked with settlements were defined around Corsica. Then, the J’MAMBI, based on the polluo-sensitivity of species, the richness, the diversity of the settlements and their equitability was developed, with references of good and bad ecological conditions for each habitats type. The application of this index makes possible to highlight fine variations in ecological qualities. To facilitate the identification and to decrease the time of soft-bottom macrobenthos’ study, the principle of taxonomic sufficiency is applied to the J’MAMBI. This principle makes possible to bring to the decision makers and to managers of such environmental studies, a facility diagnosis and a prompt response. Around the island, the identification at the "family" level is sufficient to give an account of ecological quality definite by a work to the "species" level. Thanks to "Benthic Methodology Simplification" or BeMSi, coupling the J’MAMBI and the facilitated identification, the two posed problems were solved. The utility of this methodology was put ahead within the framework of fish-farming survey, of outfall survey, of bay survey. Its sensitivity is also sufficient compared to other indices based on other indicators like the posidonia. Thank to this study, two types of research are possible: • The fundamental research grouping the "species" level identification and the J’MAMBI in order to improve the specific knowledge of microbenthic settlements and their reaction under or without disturbances. • The applied research using the BeMSi in order to obtain a general overview of the ecological quality status of an area and to help with decision making. In the future, it would be interesting to apply the results of this thesis to long temporal series of data and to other geographical areas in order to confirm the robustness of the index and the methodology developed. [less ▲]

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See detailMacrocyle-embedded b-lactams as novel inhibitors of the Penicillin Binding Protein PBP2a from MRSA
Dive, Georges ULg; Bouillon, Camille; Sliwa, Aline et al

in European Journal of Medicinal Chemistry (2013), 64

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See detailMacroecological patterns of genetic structure and diversity in the aquatic moss Platyhypnidium riparioides
Hutsemekers, Virginie ULg; Hardy, O. J.; Mardulyn, P. et al

in New Phytologist (2010)

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See detailThe Macroeconomics of PAYG Pension Schemes in an Ageing Society
Artige, Lionel ULg

Conference (2016, March 10)

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See detailThe Macroeconomics of PAYG Pension Schemes in an Aging Society
Artige, Lionel ULg

Conference (2014, May 16)

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See detailThe Macroeconomics of PAYG Pension Schemes in an Aging Society
Artige, Lionel ULg; Cavenaile, Laurent; Pestieau, Pierre ULg

E-print/Working paper (2014)

Detailed reference viewed: 47 (2 ULg)