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See detailA Place Within: Rediscovering India
Munos, Delphine ULg

in South Asian Diaspora (2010), 2(1), 139-141

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See detailPlace(s) et rôle(s) de l’éducateur physique dans la société contemporaine
Cloes, Marc ULg

Conference given outside the academic context (2007)

Si, au fil du 20ème siècle, le sport est devenu un véritable phénomène social et économique, l’activité physique semble prendre une place croissante dans les préoccupations actuelles. Les deux concepts ... [more ▼]

Si, au fil du 20ème siècle, le sport est devenu un véritable phénomène social et économique, l’activité physique semble prendre une place croissante dans les préoccupations actuelles. Les deux concepts sont parfois utilisés sans discernement. Nous considérons toutefois qu’ils se réfèrent à des significations différentes. Dès lors, il s’avère important de les distinguer afin de mieux percevoir les modalités de pratique auxquels ils sont associés et de comprendre les nuances pouvant exister au niveau des acteurs chargés de leur organisation. Le sport est défini comme étant «toutes formes d’activités physiques qui, à travers une participation organisée ou non, ont pour objectif l’expression ou l’amélioration de la condition physique et psychique, le développement des relations sociales ou l’obtention de résultats en compétition de tous niveaux » (Conseil de l’Europe, 1992). De son côté, l’activité physique « comprend tout mouvement du corps produit par les muscles squelettiques et qui résulte en une augmentation substantielle par rapport à la dépense d’énergie de repos » (Bouchard & Shephard, 1993). Elle peut être sportive, associée au travail, aux tâches domestiques, aux déplacements ou encore aux loisirs (Sallis, Cervero, Ascher, Henderson, Kraft & Kerr, 2006). Il apparaît clairement que le concept d’activité physique englobe le sport, ce dernier n’étant qu’une forme d’activité physique. Ceci présente des implications particulièrement importantes lorsqu’il s’agit d’étudier la place et le rôle des personnes qui agissent sur le terrain et que l’on associe de plus en plus à l’effort réalisé actuellement pour lutter contre la sédentarité croissante de la population mondiale, dans la perspective de maintenir un état de santé socialement acceptable. Le terme « éducateur physique » est une expression tirée du vocabulaire québécois. [less ▲]

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See detaille placebo chez l'enfant: actualisation scientifique
Battisti, Oreste ULg

Scientific conference (2014, May)

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See detailPlacement of Piezoelectric Laminate Actuator for Active Structural Acoustic Control
Brasseur, Maud; De Boe, Pascal; Golinval, Jean-Claude ULg et al

Conference (2004)

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See detailPlacenta-Like Structure of the Aphid Endoparasitic Wasp Aphidius ervi: A Strategy of Optimal Resources Acquisition.
Sabri, Ahmed ULg; Hance, Thierry; Leroy, Pascal ULg et al

in PloS one (2011), 6(4), 18847

Aphidius ervi (Hymenoptera: Braconidae) is an entomophagous parasitoid known to be an effective parasitoid of several aphid species of economic importance. A reduction of its production cost during mass ... [more ▼]

Aphidius ervi (Hymenoptera: Braconidae) is an entomophagous parasitoid known to be an effective parasitoid of several aphid species of economic importance. A reduction of its production cost during mass rearing for inundative release is needed to improve its use in biological control of pests. In these contexts, a careful analysis of its entire development phases within its host is needed. This paper shows that this parasitoid has some characteristics in its embryological development rather complex and different from most other reported insects, which can be phylogenetically very close. First, its yolkless egg allows a high fecundity of the female but force them to hatch from the egg shell rapidly to the host hemocoel. An early cellularisation allowing a rapid differentiation of a serosa membrane seems to confirm this hypothesis. The serosa wraps the developing embryo until the first instar larva stage and invades the host tissues by microvilli projections and form a placenta like structure able to divert host resources and allowing nutrition and respiration of embryo. Such interspecific invasion, at the cellular level, recalls mammal's trophoblasts that anchors maternal uterine wall and underlines the high adaptation of A. ervi to develop in the host body. [less ▲]

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See detailPlacental and gastric aspartic proteinases: new insights from bovine species
Bella, Amina ULg; Beckers, Jean-François ULg; Melo de Sousa, Noelita ULg

in Proceedings of the 2nd Scientific Meeting of the Faculty of Veterinary Medicine (2012, October 19)

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See detailPlacental and Pituitary Growth Hormone Secretion During Pregnancy in Acromegalic Women
Beckers, Albert ULg; Stevenaert, Achille ULg; Foidart, Jean-Michel ULg et al

in Journal of Clinical Endocrinology and Metabolism (1990), 71(3), 725-31

It is now well established that during the second half of normal pregnancy, the human placenta secretes its specific GH variant (placental GH) in increasing amounts up to delivery. During the same period ... [more ▼]

It is now well established that during the second half of normal pregnancy, the human placenta secretes its specific GH variant (placental GH) in increasing amounts up to delivery. During the same period, pituitary GH secretion is progressively suppressed. The present study was aimed at clarifying the physiology of GH secretion in pregnant acromegalic women. Two young women remained acromegalic despite transphenoidal removal of their pituitary adenoma. Increased basal levels of GH and insulin-like growth factor-I (IGF-I) as well as paradoxical GH release after TRH injection were noted. Both women became pregnant and delivered term babies without any complication. In both patients, pituitary GH remained elevated during the entire pregnancy, contrary to the situation in normal women. Paradoxical GH release after TRH treatment was also present, whereas no response was observed in five normal control subjects. GH pulsatility studies revealed a highly pulsatile secretory pattern of pituitary GH, in contrast to that in normal woman, whose placental GH is secreted tonically. Tissue placental GH concentrations were within the range of levels in normal placentas. An increase in serum IGF-I in late pregnancy was also similar to that observed in normal pregnancy. These findings confirm that increased IGF-I levels are not pituitary GH dependent in late pregnancy. They add new evidence that adenomatous somatotrophs lack an IGF-I-dependent feedback regulation present in normal somatotrophs. [less ▲]

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See detailPlacental GH, IGF-I, IGF-binding protein-1 and leptin during a glucose challenge test in pregnant women : relation with maternal body weight, glucose tolerance, and birth weight
Verhaeghe, J.; Pintiaux, Axelle ULg; Van Herck, E. et al

in Journal of Clinical Endocrinology and Metabolism (2002), 87(6), 2875-2882

The prediction of birth weight may be improved by the measurement of hormones or growth factors in the mother. We measured body weight (BW) and plasma levels of placental GH (PGH), IGF-I, IGF-binding ... [more ▼]

The prediction of birth weight may be improved by the measurement of hormones or growth factors in the mother. We measured body weight (BW) and plasma levels of placental GH (PGH), IGF-I, IGF-binding protein-1 (IGFBP-1), and leptin at the time of the glucose challenge test (GCT) in 289 women, who were pregnant with a single fetus, between 24 and 29 wk gestational age (GA). Delivery occurred 12 +/- 2 (mean +/- SD) wk later. First, we examined which variables regulate these hormonal factors. Multiple regression showed that PGH concentrations were determined by GA at sampling and were negatively related to BW. IGF-I levels were mainly determined by PGH, and also by insulin, BW, and (negatively) age. IGFBP-1 concentrations were negatively determined by BW, insulin, and IGF-I. BW was also a powerful determinant of leptin levels, with insulin as a less robust determinant. Second, we examined the relation to glucose levels. PGH, IGF-I, and IGFBP-1 concentrations were not correlated with post-GCT glucose levels and were comparable in women with a normal or disturbed GCT (glucose >/=7.8 mmol/liter; n = 72). Finally, we examined the relation with birth weight and placental weight. Birth weight, corrected for GA and stratified into percentile groups, and the ponderal index at birth were strongly related to maternal BW, but not to maternal PGH, IGF-I, or IGFBP-1 levels. Neither was maternal leptin related to birth weight, but leptin concentrations were slightly higher in women who delivered obese babies. Placental weight was not related to any of the hormonal factors. This prospective study indicates that the variation in circulating PGH, IGF-I, IGFBP-1, and leptin between 24 and 29 wk of pregnancy is strongly dependent on maternal BW, but is unrelated to glucose tolerance. In addition, the measurement of PGH, IGF-I, IGFBP-1, or leptin at the time of the GCT is not useful clinically to predict birth weight. [less ▲]

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See detailPlacental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization
Rakic, Jean-Marie ULg; Lambert, Vincent ULg; Devy, Laetitia et al

in Investigative Ophthalmology & Visual Science (2003), 44(7), 3186-3193

PURPOSE. VEGF has been shown to be necessary, but not sufficient alone, for the development of subretinal pathologic angiogenesis. In the current study, the influence of placental growth factor (PIGF), a ... [more ▼]

PURPOSE. VEGF has been shown to be necessary, but not sufficient alone, for the development of subretinal pathologic angiogenesis. In the current study, the influence of placental growth factor (PIGF), a member of the VEGF family, in human and experimental choroidal neovascularization (CNV) was investigated. METHODS. The presence of VEGF family member mRNA was evaluated by RT-PCR in neovascular membranes extracted during surgery. The spatial and temporal pattern of VEGF isoforms and PIGF mRNA expression were explored by using the laser capture catapulting technique and RT-PCR in a murine laser-induced model and in vitro. PIGF expression was also studied in human donor eyes. The influence of endogenous PIGF was evaluated in deficient mice (PlGF(-/-)) and by antibody-mediated neutralization of the PIGF receptor. RESULTS. Human neovascular membranes consistently expressed VEGF-A, -B, and -C; PlGF; and VEGFR-1 and -2. The VEGF(120) isoform mRNA was primarily induced in early stages of angiogenesis in vivo and in vitro. PIGF mRNA expression was present in the intact choroid and significantly upregulated during the course of experimental CNV. Both deficient PIGF expression in PIGF(-/-) mice and PIGF receptor neutralization in wild-type mice prevented the development of choroidal neovascularization induced by laser. CONCLUSIONS. These observations demonstrate the participation of PIGF in experimental CNV. They identify therefore PIGF as an additional promising target for ocular antiangiogenic strategies. [less ▲]

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See detailPlacental growth factor: a tissue modelling factor with therapeutic potentials in neurology?
Chaballe, Linda ULg; Schoenen, Jean ULg; Franzen, Rachelle ULg

in Acta Neurologica Belgica (2011), 111(1), 10-7

Placental growth factor (PlGF) is an angiogenic factor that belongs to the vascular endothelial growth factor (VEGF) family. Besides its well known capacity to potentiate the angiogenic action of VEGF ... [more ▼]

Placental growth factor (PlGF) is an angiogenic factor that belongs to the vascular endothelial growth factor (VEGF) family. Besides its well known capacity to potentiate the angiogenic action of VEGF, PlGF also participates in inflammatory processes by attracting and activating monocytes; it plays therefore more specifically a role in pathological conditions. PIGF and its two receptors, VEGFR-1 and neuropilins (NRPs), are expressed in the brain and increase after experimental stroke, but their precise functions in the nervous system remain underexplored. In this review article, we summarize present knowledge on the role of PlGF in various nervous system disease processes. Given the available data, P1GF has neuroprotective and neurotrophic properties that make it an actor of considerable interest in the pathophysiology and potentially in the therapy of degenerative and traumatic brain or spinal cord diseases. [less ▲]

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See detailPlacental growth hormone (GH), GH-binding protein, and insulin-like growth factor axis in normal, growth-retarded, and diabetic pregnancies: Correlations with fetal growth
McIntyre, H. D.; Serek, R.; Crane, D. I. et al

in Journal of Clinical Endocrinology and Metabolism (2000), 85(3), 1143-1150

We previously described significant changes in GH-binding protein (GHBP) in pathological human pregnancy. There was a substantial elevation of GHBP in cases of noninsulin-dependent diabetes mellitus and a ... [more ▼]

We previously described significant changes in GH-binding protein (GHBP) in pathological human pregnancy. There was a substantial elevation of GHBP in cases of noninsulin-dependent diabetes mellitus and a reduction in insulin-dependent diabetes mellitus. GHBP has the potential to modulate the proportion of free placental GH (PGH) and hence the impact on the maternal GH/insulin-like growth factor I (IGF-I) axis, fetal growth, and maternal glycemic status. The present study was undertaken to investigate the relationship among glycemia, GHBP, and PGH during pregnancy and to assess the impact of GHBP on the concentration of free PGH. We have extended the analysis of specimens to include measurements of GHBP, PGH, IGF-I, IGF-II, IGF-binding protein-1 (IGFBP-1), IGFSP-2, and IGFBP-3 and have related these to maternal characteristics, fetal growth, and glycemia. The simultaneous measurement of GHBP and PGH has for the first time allowed calculation of the free component of PGH and correlation of the free component to indexes of fetal growth and other endocrine markers. PGH, free PGH, IGF-I, and IGF-II were substantially decreased in IUGR at 28-30 weeks gestation (K28) and 36-38 weeks gestation (K36). The mean concentration (+/-SEM) of total PGH increased significantly from K28 to K36 (30.0 +/- 2.2 to 50.7 +/- 6.2 ng/mL; n = 40), as did the concentration of free PGH (23.4 +/- 2.3 to 43.7 +/- 6.0 ng/mL; n = 38). The mean percentage of free PGH was significantly less in IUGR than in normal subjects (67% vs. 79%; P < 0.01). Macrosomia was associated with an increase in these parameters that did not reach statistical significance. Multiple regression analysis revealed that PGH/IGF-I and IGFBP-5 account for 40% of the variance in birth weight. IGFBP-3 showed a significant correlation with IGF-I, IGF-II, and free and total PGK at K28 and K36. Noninsulin-dependent diabetes mellitus patients had a lower mean percentage of free PGH (65%; P < 0.01), and insulin-dependent diabetics had a higher mean percentage of free PGH (87%; P < 0.01) than normal subjects. Mean postprandial glucose at K28 correlated positively with PGH and free PGH (consistent with the hyperglycemic action of GH). GHBP correlated negatively with both postprandial and fasting glucose. Although GHBP correlated negatively with PGH (r = -0.52; P <.001), free PGH and total PGH correlated very closely (r = 0.98). The results are consistent with an inhibitory function for GHBP in vivo and support a critical role for placental GH and IGF-I in driving normal fetal growth. [less ▲]

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See detailPlacental growth hormone and IGF-I in a pregnant woman with Pit-1 deficiency
Verhaeghe, J.; Bougoussa, M.; Van Herck, E. et al

in Clinical Endocrinology (2000), 53(5), 645-647

The respective contributions of pituitary and placental GH to circulating IGF-I in pregnant women have not been well established. We measured the serum concentrations of placental growth hormone (PGH) and ... [more ▼]

The respective contributions of pituitary and placental GH to circulating IGF-I in pregnant women have not been well established. We measured the serum concentrations of placental growth hormone (PGH) and IGF-I in a woman with pit-1 deficiency before, during and after pregnancy, resulting in the birth of a healthy child (not pit-1 deficient). Both PGH and IGF-I concentrations were below the assay detection limit before and after pregnancy. During pregnancy, PGH and IGF-I levels increased steadily; the concentrations of PGH and IGF-I in late pregnancy were comparable with levels previously measured in normal pregnancies. PGH and IGF-I concentrations were strongly correlated throughout pregnancy (r = 0.90; P = 0.002). PGH was undetectable in cord serum, whilst the IGF-I concentration was within the normal range. The findings of this case study corroborate the notion that PGH is the prime regulator of maternal serum IGF-I during pregnancy. [less ▲]

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See detailPlacental growth hormone secretion is not influenced in vivo by octreotide therapy
Caron, P.; Igout, A.; Hennen, Georges ULg et al

in 10th international Congress of Endocrinology - Abstract book (1996)

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See detailPLACENTAL GROWTH-HORMONE - SIGNIFICANCE RELATIVE TO PITUITARY GROWTH-HORMONES AND PLACENTAL-LACTOGEN HORMONE
Hennen, Georges ULg; Frankenne, Francis ULg; Scippo, Marie-Louise ULg et al

in Reproduction Nutrition Development (1988), 28(6B), 1699-1706

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See detailPlacental proteins in ruminants: biochemical, physiological and zootechnical aspects
Melo de Sousa, Noelita ULg; Figueiredo, J. R.; Beckers, Jean-François ULg

in Renaville, R.; Burny, A. (Eds.) Biotechnology in Animal Husbandry (2001)

During the last decade, investigations were carried out by several research groups in order to characterize proteins or glycoproteins synthesized in the ruminant placenta. Recently, as results of this ... [more ▼]

During the last decade, investigations were carried out by several research groups in order to characterize proteins or glycoproteins synthesized in the ruminant placenta. Recently, as results of this research, a large family of pregnancy-associated glycoproteins (PAGs) was discovered. Using molecular biology techniques, they were found to be members of the superfamily of the aspartic proteinases which also contains pepsinogen, chymosin, renin, beta-secretase, cathepsin D and E etc. Synthesized in the mono and/or binucleate cells of the trophoblast, some forms of PAG seem to lack of proteinase activity. It is likely they are synthesized together with molecules involved in the tissue remodeling of the placenta. Their release in large quantities into the maternal blood circulation results in measurable plasma concentrations. Thanks to international collaborative studies, we have shown that PAG levels are a good indicator of feto-placental well-being and that sharp decreases in PAG levels occur just before pregnancy failure in cows and in goats. In some countries, the PAG assay is available for veterinarians in the regional laboratories responsible for animal health including immunodiagnosis for brucellosis, IBR, BVD, CAEV, VISNA-MEDI etc. [less ▲]

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See detailPlacental proteins secreted in maternal circulation: useful indicators for both pregnancy diagnosis and embryonic mortality in bovine species
Moreira da Silva, F.; Melo de Sousa, Noelita ULg; Figueiredo, J. R. et al

in Revista Portuguesa de Zootecnia (2003), 10(1), 99-121

During the last decades, several research groups developed investigations in order to characterize proteins or glycoproteins synthesized by ruminant placenta. As result of these investigations, a large ... [more ▼]

During the last decades, several research groups developed investigations in order to characterize proteins or glycoproteins synthesized by ruminant placenta. As result of these investigations, a large family of pregnancy-associated glycoproteins was identified in bovine ovine and caprine placenta. By using molecular biology techniques, it was demonstrated that they are members of the aspartic proteinase superfamily, in which they co-exist with pepsinogens, renin, cathepsin D and E, etc. Due to their secretion in large amounts by the trophoblastic binucleated cells, bovine PAGs are detectable in maternal circulation soon after implantation. In the present work, in addition to the physiological and biochemical characterization of bovine PAGs, it will be showed how the measurement of PAG concentrations in maternal blood is useful for both pregnancy confirmation and follow-up of the fetus-placental well-being. Available information related to other placental proteins will be also discussed. [less ▲]

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See detailPlacing the academic library at the center of veterinary PhD students' training
Brouwir, Christine ULg; Vandenput, Sandrina ULg; Maas, Michel et al

in Journal of the European Association for Health Information and Libraries (2008, August), 4(3), 18-20

For several years academic librairies have been actively involved in information literacy instruction. However, the required competences are different for PhD students and in the case of the Veterinary ... [more ▼]

For several years academic librairies have been actively involved in information literacy instruction. However, the required competences are different for PhD students and in the case of the Veterinary Faculty of the University of Liège (Belgium), good Faculty-Librarian collaborations have been developed. Specific targeted courses and training sessions concerning information literacy have been officially incorporated in the PhD curriculum, with the main objective being to help PhD students to be autonomous and efficient in the elaboration of scientific publications, an essential stage of their scientific career. [less ▲]

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