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See detailPhotodissociation spectroscopy of cationic porphyrins in the gas phase. Influence of the complexation with DNA. Comparison with solution phase
Rosu, Frédéric ULg; De Pauw, Edwin ULg; Gabelica, Valérie ULg et al

in Beck, Rainer D.; Drabbels, Marcel; Rizzo, Thomas R. (Eds.) Contributions 16th Symposium on Atomic and Surface Physics and Related Topics (2008)

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See detailPhotodynamic therapy and imiquimod immunotherapy for basal cell carcinomas
Nikkels, Arjen ULg; Pierard-Franchimont, Claudine ULg; Tassoudji, Nazli ULg et al

in Acta Clinica Belgica (2005), 60(5, Sep-Oct), 227-234

Photodynamic therapy (PDT) and topical imiquimod immunotherapy (TII) are two recently introduced treatment modalities for certain types of basal cell carcinomas (BCC). We present a review of the relevant ... [more ▼]

Photodynamic therapy (PDT) and topical imiquimod immunotherapy (TII) are two recently introduced treatment modalities for certain types of basal cell carcinomas (BCC). We present a review of the relevant literature and report our own findings regarding the efficacy and tolerance of PDT and TII in the treatment of BCCs. According to published studies, the cure rates range from 75-95% for PDT and 42-100% for TII, depending on treatment modalities and BCC type. In our observations, 13 patients with nodular or superficial BCCs were treated by PDT using two courses of 3-hour topical application of methyl aminolevulinate, followed by 8 minutes illumination (lambda = 634 rim, e = 37J/cm(2)). Biopsies were taken before and one month after PDT. Side effects including pain and crusting were assessed. Eight patients with superficial BCC were treated by TII using 3 monthly courses each consisting of 3 weekly applications for 3 weeks followed by one week out of treatment. Biopsies were taken before and after 3 months of TII. Adverse reactions including erythema, oozing, ulceration, and crusting were recorded. Clinico-histological cure was obtained in 12/13 PDT cases as assessed after I month, and in 6/8 TII cases after 3 months. Minimal pain during illumination and crust formation were observed in 7/13 and 3/13 PDT cases, respectively. Variable erythema, oozing, ulceration, and crusting were observed in all TII-treated lesions. It is concluded that PDT represents an active and well tolerated alternative treatment for both nodular and superficial BCCs. TII also shows activity, although the tolerance may be poor and cure needs a longer time to be obtained. The final cosmetic appearance was fine following both PDT and TII procedures. Both PDT and TII may leave intact neoplastic aggregates inside the skin. They cannot be clinically perceived, leading to unexpected recurrences. It is stressed that the currently available efficacy information about PDT and TII deals with short term follow-up periods. A 5-year follow-up must be awaited before drawing firm conclusions. [less ▲]

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See detailPhotodynamic therapy for cutaneous carcinoma
NIKKELS, Arjen ULg; thirion, L.; QUATRESOOZ, Pascale ULg et al

Poster (2007)

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See detailPHOTODYNAMIC THERAPY FOR MULTI-RESISTANT CUTANEOUS LANGERHANS CELL HISTIOCYTOSIS
FAILLA, Valérie ULg; WAUTERS, Odile ULg; CAUCANAS, MARIE et al

in Rare Tumors (2010), 2:e34

Langerhans cell histiocytosis is a rare group of proliferative disorders. Beside cutaneous involvement, other internal organs ca be affected. The treatment of cutaneous lesions is difficult and relies on ... [more ▼]

Langerhans cell histiocytosis is a rare group of proliferative disorders. Beside cutaneous involvement, other internal organs ca be affected. The treatment of cutaneous lesions is difficult and relies on topical corticosteroids, carmustine, nitrogen mustard, and photochemotherapy. Systemic steroids and vinblastine are used for recalcitrant skin lesions. Howerver, some cases fail to respond. An 18-month old boy presented a CD1a+, S100a+ Langerhans cell histocytosis with cutaneous and severe scalp involvement. Topical corticosteroids and nitrogen mustard failed to improve the skin lesions. Systemic corticosteroids and vinblastine improved the truncal involvement but had no effect on the scalp lesions. Methylaminolevulinate (MAL) based photodynamic therapy (PDT) resulted in a significant regression of the scalp lesions. Control histology revealed an almost complete clearance of the tumor infiltrate. Clinical follow-up after six months showed no recurrence. Although spontaneous regression of cutaneous Langerhans cell histiocytosis is observed, the rapid effect of photodynamic therapy for refractory skin lesions. Larger series are needed to determine whether photodynamic therapy deserves a place in the treatment of multiresistant cutaneous Langerhans cell histiocytosis. [less ▲]

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See detailPhotodynamic therapy of cancer: an update.
Agostinis, Patrizia; Berg, Kristian; Cengel, Keith A et al

in CA : A Cancer Journal for Clinicians (2011), 61(4), 250-81

Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure involves administration of ... [more ▼]

Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure involves administration of a photosensitizing agent followed by irradiation at a wavelength corresponding to an absorbance band of the sensitizer. In the presence of oxygen, a series of events lead to direct tumor cell death, damage to the microvasculature, and induction of a local inflammatory reaction. Clinical studies revealed that PDT can be curative, particularly in early stage tumors. It can prolong survival in patients with inoperable cancers and significantly improve quality of life. Minimal normal tissue toxicity, negligible systemic effects, greatly reduced long-term morbidity, lack of intrinsic or acquired resistance mechanisms, and excellent cosmetic as well as organ function-sparing effects of this treatment make it a valuable therapeutic option for combination treatments. With a number of recent technological improvements, PDT has the potential to become integrated into the mainstream of cancer treatment. [less ▲]

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See detailPhotodynamic therapy using methyl aminolevulinate in the management of primary superficial basal cell carcinoma: Clinical an health economic outcomes
Caekelbergh, K.; Nikkels, Arjen ULg; Leroy, B. et al

in Journal of Drugs in Dermatology (2009)

Background: Basal cell carcinoma (BBC) is the most common form of skin cancer worldwide. Different treatment options exist. The efficacy of photodynamic therapy with methyl aminolevulinate (MAL-PDT) has ... [more ▼]

Background: Basal cell carcinoma (BBC) is the most common form of skin cancer worldwide. Different treatment options exist. The efficacy of photodynamic therapy with methyl aminolevulinate (MAL-PDT) has been established in several randomized controlled trials (RCTs). Real life data can differ greatly from data derived from randomized controlled trials (RCTs). Objectives: To describe the results of a Belgian observational study concerning superficial BCC (sBCC) vis-à-vis clinical and health economic outcomes in order to evaluate the real-life practice of MAL-PDT. Methods: This study was a prospective, single-arm, open study conducted at eight dermatological institutions during six months after the first MAL-PDT treatment. Eligible patients had to present with lesions, suitable for MAL-PDT according to Belgian reimbursement criteria. Resource use was collected during the study period. Clinical Response (CR) and Cosmetic Outcome (CO), as well as cost of care were evaluated. A subset analysis of patients with sBCC only was conducted. Results: Ninety patients were identified for the analysis (mean age 65 years; 61 % female). The mean number of lesions per patient was 1.6, mostly located on the face, the back and the chest. For the entire period, the mean number of visits to a dermatologist was 4 per patient including two MAL-PDT sessions. The average, cumulative amount of MAL used per treatment was 1,256 mg. Two patients experienced adverse events at the application site, none of them serious, all resolved completely. The CR rate was 89 % at the end of the study. The CO was “excellent” or “good” in 96 % of the patients. Total cost of care was €289 ($ 414 U.S.) per patient. Cost per lesion was €195 ($ 280 U.S.). Conclusion: The result from the real-life practice study confirm the efficacy found in prior, prospective randomized trials. About four visits and less than one tube of MAL are needed for the full treatment of sBCC in one patient. [less ▲]

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See detailPhotoelastic effects in Single-Mode Optical Fibers
Roose, Stéphane ULg; Bastiaensens, Jan

Scientific conference (1987, June 04)

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See detailPhotoelectric Conversion Effect in Non-Photovoltaic Photorefractive Materials
Frejlich, Jaime; De Oliveira, Ivan; Carvalho, Jesiel et al

in Latin America Optics & Photonics Conference (LAOP) - OSA Technical Digest (online) (2014, November)

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See detailA photoelectric investigation of light variability in Ap stars
Hensberge, H.; Deridder, G.; Doom, C. et al

in Astronomy and Astrophysics. Supplement Series (1981), 46

A study of the light variability of a number of peculiar A stars, mainly in Stromgren colors u and v and in peculiarity index Delta-a, leads to the proposal of the following light variability periods: (1 ... [more ▼]

A study of the light variability of a number of peculiar A stars, mainly in Stromgren colors u and v and in peculiarity index Delta-a, leads to the proposal of the following light variability periods: (1) HD 5601, 1.11 days; (2) HD 19712, 2.19 days; (3) HD 30849, 15.86 days; (4) HD 38823, 8.64 days; (5) HD 53116, 11.98 or 18.10 days; (6) HD 56022, 0.92 days; and (7) HD 81009, 33.97 days. In addition, evidence is given for variability of HD 94660 on a time scale on the order of months or years, and it is shown that the rotation period proposed by Borra and Landstreet (1980) for HD 25267 is not supported by the light variations observed. The character of Delta-a variability is discussed. [less ▲]

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See detailPhotoelectric light curves of minor planets 599 Luisa and 128 Nemesis during the 1976 opposition
Debehogne, H.; Surdej, Anna ULg; Surdej, Jean ULg

in Astronomy and Astrophysics. Supplement Series (1977), 30

Asteroids 599 Luisa and 128 Nemesis were observed photometrically at the European Southern Observatory during the 1976 opposition. The light curve of 599 Luisa shows two well-shaped minima and maxima ... [more ▼]

Asteroids 599 Luisa and 128 Nemesis were observed photometrically at the European Southern Observatory during the 1976 opposition. The light curve of 599 Luisa shows two well-shaped minima and maxima together with a short-time-scale feature. The synodic period of rotation found for 599 Luisa 9 hr 33 min 58 (+ or -46) sec, and the maximum amplitude of the light curve is 0.18 mag. Minor planet 128 Nemesis could only be observed during one night and appears to be a slowly rotating asteroid. [less ▲]

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See detailPhotoelectric lightcurves and rotation period of the minor planet 148 Gallia
Surdej, Anna ULg; Surdej, Jean ULg

in Astronomy and Astrophysics. Supplement Series (1979), 37

Abstract image available at: http://esoads.eso.org/abs/1979A&AS...37..471S

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See detailPhotoelectric lightcurves and rotation period of the minor planet 201 Penelope
Surdej, Jean ULg; Louis, B.; Cramer, N. et al

in Astronomy and Astrophysics. Supplement Series (1983), 54

Results of photoelectric observations of the asteroid 201 Penelope carried out at the European Southern Observatory and Perth Observatory during the 1980 opposition of the asteroid between October 6 and ... [more ▼]

Results of photoelectric observations of the asteroid 201 Penelope carried out at the European Southern Observatory and Perth Observatory during the 1980 opposition of the asteroid between October 6 and November 7 are presented. Observations were made in the standard UBV and Geneva systems at ESO, and in V-prime at Perth. Examination of composite light curves shows the presence of two distinct maxima and two distinct minima, with a total amplitude of the V light curve of 0.52 magnitudes. A mean synodic rotation period of 3 h, 44 min, 51.6 + or - 7.4 sec is derived. Using a mean phase coefficient beta[SUB]V[/SUB] = 0.037 mag/deg, a primary V (1,0) maximum of 8.51 + or - 0.01 magnitudes is obtained. Color indices are measured as B-V = 0.70 + or - 0.01 and U-B = 0.23 + or - 0.02 magnitudes, and previously reported color variations (Surdej and Cramer, 1980) are attributed to a failure in the reduction procedure. [less ▲]

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See detailPhotoelectric lightcurves and rotation period of the minor planet 59 Elpis
Debehogne, H.; Surdej, Anna ULg; Surdej, Jean ULg

in Astronomy and Astrophysics. Supplement Series (1978), 33

Abstract image available at: http://esoads.eso.org/abs/1978A&AS...33....1D

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See detailPhotoelectric lightcurves of the minor planets 29 Amphitrite, 121 Hermione and 185 Eunike
Debehogne, H.; Surdej, Anna ULg; Surdej, Jean ULg

in Astronomy and Astrophysics. Supplement Series (1978), 32

Abstract image available at: http://esoads.eso.org/abs/1978A&AS...32..127D

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See detailPhotoelectric observations of two unusual asteroids - 1978 CA and 1978 DA
Schuster, H. E.; Surdej, Anna ULg; Surdej, Jean ULg

in Astronomy and Astrophysics. Supplement Series (1979), 37

The two fast-moving asteroids 1978 CA and 1978 DA, discovered in February 1978 with the ESO Schmidt telescope at La Silla (Chile), were observed with a photoelectric photometer attached to the 1-m ESO ... [more ▼]

The two fast-moving asteroids 1978 CA and 1978 DA, discovered in February 1978 with the ESO Schmidt telescope at La Silla (Chile), were observed with a photoelectric photometer attached to the 1-m ESO telescope. The light curve of 1978 CA displays two fairly symmetric maxima and minima with a total amplitude of 0.8 mag in V. The synodic period of rotation found is 3 h 45 m and places 1978 CA as the third fastest rotator among all known solar objects. Concerning the minor planet 1978 DA, light variations covering one full cycle of rotation could not be monitored. Nevertheless, the rotation period exceeds 5 h, and the total amplitude is greater than 0.35 mag. [less ▲]

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See detailPhotoelectric photometry of 22 Kalliope during the 1985 opposition and determination of its pole orientation - The 'magnitude-aspect' relations revisited
Surdej, Jean ULg; Pospieszalska-Surdej, Anna ULg; Michalowski, T. et al

in Astronomy and Astrophysics (1986), 170

Abstract image available at: http://esoads.eso.org/abs/1986A&A...170..167S

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See detailPhotoelectric photometry of Comet Halley from Mt Tamborine observatory
Page, A. A.; Nielsen, G. E.; Jones, K. L. et al

in Vistas in Astronomy (1988), 31

Post-perihelion photoelectric observations of comet Halley carried out during several weeks are reported. The measurements confirm the existence of large-amplitude night-to-night changes.

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See detailPhotoelectric photometry of the peculiar emission-line star GG Carinae
Gosset, Eric ULg; Surdej, Jean ULg; Swings, J.-P.

in Astronomy and Astrophysics. Supplement Series (1984), 55

The first extensive sets of photoelectric observations of the peculiar emission-line star GG Carinae were obtained from 1977 to 1981, in both the standard UBV and Strömgren systems. A Fourier analysis of ... [more ▼]

The first extensive sets of photoelectric observations of the peculiar emission-line star GG Carinae were obtained from 1977 to 1981, in both the standard UBV and Strömgren systems. A Fourier analysis of 767 independent measurements leads to the determination of a period P = 31[SUP]d[/SUP].020 for the light variations. Different physical arguments based on the analysis of the present photoelectric - as well as previous photographic - data clearly indicate, however, that the true period is P = 62[SUP]d[/SUP].039. The resulting composite lightcurve displays two distinct maxima and minima with a total light amplitude Deltam â ¡ 0.5 mag. Additional interesting features are noticed in the mean lightcurve. Although it is not possible to classify GG Carinae among any known type of variable stars, the light variations of this object are similar to those observed for beta Lyrae-type systems. [less ▲]

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See detailPhotoelectric scans of comet Halley.
Sterken, C.; Manfroid, Jean ULg; Hutsemekers, Damien ULg et al

in Diversity and Similarity of Comets (1987, September 01)

The authors compare radial photometric scans of comet Halley obtained in April 1986 at the European Southern Observatory, La Silla, Chile, with theoretical profiles derived from Haser's model.

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