Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
See detailPadvinder voor het leven
Meesters, Gert ULg

Article for general public (2009)

Detailed reference viewed: 13 (2 ULg)
Full Text
Peer Reviewed
See detailPaedomorphosis in the Alpine newt (Triturus alpestris): decoupling behavioural and morphological change
Denoël, Mathieu ULg

in Behavioral Ecology and Sociobiology (2002), 52(5), 394-399

Paedomorphosis is a heterochronic pattern leading to morphological change, i.e. retention of larval characters in the adult phenotype. The aim of this study was to find out whether behaviour and ... [more ▼]

Paedomorphosis is a heterochronic pattern leading to morphological change, i.e. retention of larval characters in the adult phenotype. The aim of this study was to find out whether behaviour and morphology are decoupled in heterochronic phenotypes. To this end, I compared qualitative and quantitative aspects of courtship behaviour in syntopic metamorphic and paedomorphic Alpine newts, Triturus alpestris. Morphologically, the two morphs differ considerably (e.g. by the presence of gills only in paedomorphs), but their patterns of sexual behaviours are exhibited at similar frequencies and males use the same alternative reproductive tactics to attract unresponsive females. These results show that morphology and behaviour follow different ontogenetic pathways and are thus decoupled. Decoupling of the two traits offers the possibility of morphological evolution without alteration of sexual patterns. [less ▲]

Detailed reference viewed: 145 (16 ULg)
Peer Reviewed
See detailPAF receptor and cache-oreilles effect. Simple PAF antagonists
Lamotte-Brasseur, Josette; Heymans, Françoise; Dive, Georges ULg et al

in Lipids (1991), 26(12), 1167-1171

Detailed reference viewed: 9 (2 ULg)
Peer Reviewed
See detailPAF receptor structure: a hypothesis
Godfroid, Jean-Jacques; Dive, Georges ULg; Lamotte-Brasseur, Josette et al

in Lipids (1991), 26(12), 1162-1166

Detailed reference viewed: 9 (2 ULg)
Peer Reviewed
See detailPaf-Receptor. 1. 'Cache-Oreilles' Effect of Selected High-Potency Platelet-Activating Factor (Paf) Antagonists
Dive, Georges ULg; Godfroid, Jean-Jacques; Lamotte-Brasseur, Josette et al

in Journal of Lipid Mediators (1989), 1(4, Jul-Aug), 201-15

Three-dimensional electrostatic maps were calculated for six potent antagonists of platelet-activating factor (PAF), the antagonists being selected for their apparent structural heterogeneity. The ... [more ▼]

Three-dimensional electrostatic maps were calculated for six potent antagonists of platelet-activating factor (PAF), the antagonists being selected for their apparent structural heterogeneity. The molecules examined were the compact Ginkgolides BN 52020, BN 52021 and BN 52022 (1, 2 and 3), the semi-rigid kadsurenone (4), a flexible synthetic dinor type C furanoid lignan L-652,731 (5a) and the triazolothienobenzodiazepine WEB 2086 (7). Calculation of the electrostatic potential generated around all the above molecules showed the existence of two wells of negative potential or 'cache-oreilles' (ear-muffs), i.e., the isocontours drawn at -10 kcal/mol, located at 180 degrees from each other and separated by a maximum distance of 22-27 A. Except for the synthetic dinor type C furanoid lignan (5a), the molecules also presented a moderate hydrophobic fragment, which constitutes a third point of interaction with the high-affinity binding site in rabbit and human platelets. The findings of the present study allow speculation that this high-affinity acceptor site may be a 'polarized cylinder' with a diameter of 10-12 A. [less ▲]

Detailed reference viewed: 17 (0 ULg)
Peer Reviewed
See detailPaf-Receptor. iii. Conformational and Electronic Properties of Paf-Like Agonists and Antagonists
Lamotte-Brasseur, Josette; Dive, Georges ULg; Lamouri, Aazdine et al

in Biochimica et Biophysica Acta (1991), 1085(1), 91-105

In order to compare electronic and conformational properties of PAF-agonists and PAF-antagonists, 14 analogues structurally related to PAF were studied. A common conformation of the glycerol backbone was ... [more ▼]

In order to compare electronic and conformational properties of PAF-agonists and PAF-antagonists, 14 analogues structurally related to PAF were studied. A common conformation of the glycerol backbone was present in all agonists and all constrained or flexible antagonists. The distinction between agonists and antagonists appears to be casted on position-2 where the folded conformation of the substituent for agonists should be the most probable. In position-3 the gauche conformation can be adopted by all the analysed compounds. The electrostatic potential well at -30 kcal/mol stretches to the carbonyl group in position-2 in the folded conformation of the agonists. On the contrary, in constrained antagonists, a second negative zone appears around the carbamate group. Given the modelling results, the triethylammonium PAF analogue considered in literature as a weak agonist, was resynthesized and proved to be more potent than previously reported. These experimental results confirm our hypothesis in terms of a common conformation of agonist and antagonist PAF-like molecules. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Peer Reviewed
See detailPAF67, a novel protein that is associated with the initiation-competent form of RNA polymerase I.
Seither, P.; Iben, S.; Thiry, Marc ULg et al

in Biological Chemistry (2001), 382(8), 1163-70

Mammalian RNA polymerase I (Pol I) is a multisubunit enzyme that is decorated with accessory proteins, termed PAFs (polymerase-associated factors). The presence or absence of distinct PAFs may account for ... [more ▼]

Mammalian RNA polymerase I (Pol I) is a multisubunit enzyme that is decorated with accessory proteins, termed PAFs (polymerase-associated factors). The presence or absence of distinct PAFs may account for the functional differences of distinct fractions of cellular Pol I, and suggests that PAFs could be targets of regulatory pathways. Here we describe and functionally characterize PAF67, a novel 67 kDa protein that is tightly associated with a subpopulation of cellular Pol I. Both PAF67-containing and -deficient Pol I transcribe non-specific templates with similar efficiency, however, only the enzyme that contains PAF67 is capable of specifically transcribing rDNA templates. PAF67 co-localizes with Pol I in the nucleolus at sites of active rDNA transcription, indicating that PAF67 serves a role in rDNA transcription initiation. The results suggest that association of PAF67 with the 'core' enzyme endows Pol I with the capability to assemble into a productive transcription initiation complex at the rDNA promoter. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailPAG és progeszteron profilok alalkulás in vitro embrióbeültetést követõ vemhességnel hormanális stimuláció és petesejt kinyerés után tehenekben
Tomašković, A.; Prvanović, N.; Beckers, Jean-François ULg et al

in Proceedings: The 5th Middle-European Buiatrics Congress (2004)

Detailed reference viewed: 25 (1 ULg)
Full Text
Peer Reviewed
See detailPAG profiles in postpartum dairy cows and newborn calves
Ropstad, E; Kalberg, K; Dahl, E et al

in Reproduction in Domestic Animals (2002), 37(4), 249

In ruminants, pregnancy associated glycoproteins (PAG), synthesized in the outer layers of the trophoblast, enter the maternal bloodstream. In this study, blood samples from cows in the postpartum period ... [more ▼]

In ruminants, pregnancy associated glycoproteins (PAG), synthesized in the outer layers of the trophoblast, enter the maternal bloodstream. In this study, blood samples from cows in the postpartum period, pregnant cows and calves were collected to determine 1) the clearance rate of PAG, 2) the accuracy of PAG measurements used for pregnancy diagnosis and 3) PAG concentrations and clearance rate in newborn calves. A curvilinear decline in PAG was found with increasing days from calving. Between day 70–80 pp 3 out of 11 samples (27%) had PAG concentrations > 4 ng/ml plasma. A cut-off value of 4 ng/ml was found to give the best accuracy for pregnancy diagnosis 28–36 days after service (n ¼58: sensitivity¼0.97; specificity ¼1.0). PAG concentrations in newborn calves (n¼10) varied between 78–880 ng/ml, declining with increasing age in a curvilinear pattern to < 1 ng/ml between 20–40 days pp. In two male twin calves PAG concentrations were 880 and 101 ng/ml, respectively, at one day of age. We conclude: 1) 4 ng PAG /ml provides the best cut-off value for pregnancy diagnosis. 2) Cows serviced before 60 days pp can produce false positive pregnancy diagnoses due to PAG originating from the previous pregnancy. 3) High PAG concentrations can be found in newborn calves. [less ▲]

Detailed reference viewed: 1 (0 ULg)
See detailPage de Beckett et Beckett de Page
Demoulin, Laurent ULg

E-print/Working paper (2013)

Compte rendu du livre de Martin Page L'Apiculture selon Samuel Beckett.

Detailed reference viewed: 7 (1 ULg)
Full Text
Peer Reviewed
See detailPaget’s disease of bone : diagnosis and management
Hosking, D; Meunier, PJ; Ringe, JD et al

in British Medical Journal (1996), 312

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailPaget's Disease of Bone Treated with a Five Day Course of Oral Tiludronate
Reginster, Jean-Yves ULg; Lecart, Marie-Paule ULg; Deroisy, Rita ULg et al

in Annals of the Rheumatic Diseases (1993), 52(1), 54-7

Chloro-4-phenyl thiomethylene bisphosphonate (tiludronate) is a new drug which can be used as an inhibitor of bone resorption. As it remains in bone for a long time, and as mineralisation defects have ... [more ▼]

Chloro-4-phenyl thiomethylene bisphosphonate (tiludronate) is a new drug which can be used as an inhibitor of bone resorption. As it remains in bone for a long time, and as mineralisation defects have only been seen at doses much higher than those required to decrease osteoclastic activity, it could be given at high doses over a short period of time. Eighteen patients with Paget's disease of bone were randomly allocated to three therapeutic groups receiving respectively 600, 800, and 1200 mg/day tiludronate for five days. Serum alkaline phosphatase activity and the urinary hydroxyproline/creatinine ratio were quickly and drastically reduced in all three groups. A significant reduction of serum alkaline phosphatases and the hydroxyproline/creatinine ratio was still present six months after the five day therapeutic course, reflecting a sustained activity of tiludronate even after stopping treatment. Dose dependent short and long term reductions of bone turnover rate were observed. Biochemical assessment of haematological, renal, or hepatic tolerance did not show any toxicity of tiludronate. Fifty per cent of patients treated by a dose of 1200 mg/day reported gastrointestinal disturbances, however, making this dosage unsuitable for clinical practice. [less ▲]

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailPágina impar: el lugar del traductor en el auge de la industria editorial
Willson, Patricia ULg

in Saítta, Sylvia (Ed.) Historia crítica de la literatura argentina. Volumen 9: El oficio se afirma (2004)

This chapter examines the place occupied by the translator during the period in which Buenos Aires was the publishing Mecca of Latin America. Starting in the 1930s and during the forties and fifties ... [more ▼]

This chapter examines the place occupied by the translator during the period in which Buenos Aires was the publishing Mecca of Latin America. Starting in the 1930s and during the forties and fifties, translating activity was particularly intense in Argentina and incorporated a profusion of what was being written in other literatures. Two realities converged in this boom: a favourable context of the book market and a tradition of handling «the new» set forth by the porteño avant-gardes of the 1920s. [less ▲]

Detailed reference viewed: 58 (18 ULg)