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See detailPituitary gland in MEN1 syndrome : from histopathology to prognosis
Villa, C; Bernier, M; Gaillard, S et al

in Abstract book - 14th International Workshop on Multiple Endocrine Neoplasia and other rare endocrine tumors (2014, September)

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See detailPituitary incidentaloma : An Endocrine Society Clinical Practice Guideline
Freda, Pamela; Beckers, Albert ULg; Katznelson, Laurence et al

in Journal of Clinical Endocrinology and Metabolism (2011)

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See detailPituitary magnetic resonance imaging in gigantism : first result after analysis of 16 cases
BECK, Emmanuel ULg; KREUTZ, Julie ULg; TSHIBANDA, Luaba ULg et al

in 23rs meeting of the Belgian Endocrine Society - Abstract book (2013, October 19)

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See detailPituitary microadenomas: diagnosis with two-and three-dimensional MR imaging at 1.5 T before and after injection of gadolinium.
Stadnik, T.; Stevenaert, Achille ULg; Beckers, Albert ULg et al

in Radiology (1990), 176(2), 419-428

The usefulness of different magnetic resonance (MR) imaging sequences (coronal and sagittal spin-echo [SE] and three-dimensional fast low-angle shot [3D FLASH]) in the detection of pituitary microadenomas ... [more ▼]

The usefulness of different magnetic resonance (MR) imaging sequences (coronal and sagittal spin-echo [SE] and three-dimensional fast low-angle shot [3D FLASH]) in the detection of pituitary microadenomas before and after gadolinium injection was prospectively evaluated in 28 patients with surgical confirmation. When evaluated separately, the most useful sequences in the detection of these microadenomas were coronal pregadolinium T1-weighted SE, coronal pregadolinium 3D FLASH, coronal postgadolinium T1-weighted SE, and coronal postgadolinium 3D FLASH. The combination of pre- and postgadolinium T1-weighted sequences with pre-and postgadolinium 3D FLASH sequences produced the highest number of true-positive findings (90%) and the lowest number of false-positive findings (5%). When a 1.5-T imaging unit with a high signal-to-noise ratio allowing useful three-dimensional acquisition is used, the authors advocate a coronal T1-weighted SE sequence, followed (if necessary) by a coronal 3D FLASH sequence, both without injection of gadolinium, in the diagnosis of pituitary microadenomas. When no confident diagnosis is reached, the same sequences should be performed after the injection of gadolinium. The sagittal pre- and postgadolinium T1-weighted SE and long-TR SE sequences are useful only in specific cases. [less ▲]

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See detailPITUITARY-HORMONES DEPENDENT EXPRESSION OF INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II IN THE IMMATURE HYPOPHYSECTOMIZED RAT TESTIS
Closset, Jean ULg; Gothot, André ULg; SENTE, Béatrice et al

in Molecular Endocrinology (1989), 3(7), 1125-1131

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See detailPituitary-specific factor binding to the human prolactin, growth hormone, and placental lactogen genes
Lemaigre, F. P.; Peers, Bernard ULg; Lafontaine, D. A. et al

in DNA (1989), 8(3), 149-59

The human genes coding for growth hormone (GH), chorionic somatomammotropin (placental lactogen, CS), and prolactin (Prl) are related evolutionarily but are expressed in phenotypically distinct cell types ... [more ▼]

The human genes coding for growth hormone (GH), chorionic somatomammotropin (placental lactogen, CS), and prolactin (Prl) are related evolutionarily but are expressed in phenotypically distinct cell types despite their nucleotide sequence homology. We show here that the promoters of the human Prl and CS genes contain cis-acting sequences that confer pituitary-specific expression in a cell-free transcription assay. Similar data are obtained with the human GH gene, consistent with earlier work by others. Footprinting analysis shows that neighboring sequences in each of these three promoters are protected from deoxyribonuclease I digestion by rat pituitary cell extracts. Footprinting competition experiments and gel retardation assays with synthetic oligonucleotides suggest that a single factor is responsible for the pituitary-specific footprints seen on the human Prl, CS, and GH genes. They also suggest that this factor is identical or closely related to the trans-acting factor GHF-1/Pit-1. Similarities with and differences from the rat GH and Prl genes are discussed. [less ▲]

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See detailPitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter
Quentien, M. H.; Manfroid, Isabelle ULg; Moncet, D. et al

in Journal of Biological Chemistry (2002), 277(46), 44408-44416

The pituitary-specific POU homeodomain factor Pit-1 likely interacts with other factors for cell-specific expression of prolactin. Here we identify the paired-like homeobox transcription factors Pitx1 and ... [more ▼]

The pituitary-specific POU homeodomain factor Pit-1 likely interacts with other factors for cell-specific expression of prolactin. Here we identify the paired-like homeobox transcription factors Pitx1 and Pitx2 as factors functionally activating the proximal human prolactin promoter (hPRL-164luc). Using in vitro binding assays and a series of site-specific mutations of the proximal hPRL promoter, we mapped the 131 and B2 bicoid sites involved in Pitx-mediated transactivation of the hPRL-164luc construct. In somatolactotroph GH4C1 cells, basal proximal hPRL promoter activity was inhibited by a Pitx2 dominant-negative form in a dose-dependent manner, whereas binding disruptive mutations in the Pitx sites significantly reduced basal activity of the promoter. We also show that synergistic activation of hPRL-164luc by Pitx2 and Pit-1 requires the integrity of the B2 Pitx binding site, and at least one of the P1 and P2 Pit-1 response elements. In addition, mutation in the B2 Pitx site results in attenuation of the promoter's responsiveness to forskolin, thyrotropin-releasing hormone, and epidermal growth factor. Conversely, Pitx1 or Pitx2 overexpression in GH4C1 cells leads to an enhancement of the drugs stimulatory effects. Altogether, these results suggest that full responsiveness to several signaling pathways regulating the hPRL promoter requires the B2 Pitx binding site and that Pitx factors may be part of the proteic complex involved in these regulations. Finally, in situ hybridization analysis showing coexpression of the PRL and Pitx2 genes in rat and human lactotroph cells corroborates the physiological relevance of these results. [less ▲]

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See detailPityriasis versicolor anhidrotique.
Uhoda, Emmanuelle ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Dermatologie Actualité (2005), 89

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See detailPius II (Aeneas Silvio Piccolomini), De duobus amantibus Euryalo et Lucretia
Adam, Renaud ULg

in De Schepper, Marcus; Kelders, Ann; Pauwels, Jan (Eds.) In de ban van boeken. Grote verzamelaars uit de negentiende eeuw in de Koninklijke Bibliotheek van België (2008)

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See detailPivé-Public, service-produit. La gestion du changement
Robert, Jocelyne ULg

Master of advanced studies dissertation (1991)

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See detailThe pivotal role of cross-calibration and quality control in an international clinical trial of the strontium salt S-12911 involving multiple DXA brands
Slosman, DO; Meunier, PJ; Delmas, PD et al

in Osteoporosis International (1996), 6(S1), 168

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See detailThe Pivotal Role of Mössbauer Spectroscopy in the Characterization of Prussian Blue and Related Iron Cyanide Complexes
Grandjean, Fernande ULg; Long, Gary J; Samain, Louise ULg

in Mössbauer Effect Reference and Data Journal (2012)

For 50 years, 57Fe Mössbauer spectroscopy has played a pivotal role in the characterization of Prussian blue complexes and many related iron cyanide complexes, a pivotal role that is extensively ... [more ▼]

For 50 years, 57Fe Mössbauer spectroscopy has played a pivotal role in the characterization of Prussian blue complexes and many related iron cyanide complexes, a pivotal role that is extensively illustrated in this paper. For the benefit of the young Mössbauer spectroscopists, the successes, the failures, and the pitfalls reported in the literature are discussed. The successes include the unquestionable distinction of iron oxidation and spin states in Prussian blue and the determination that Prussian blue and Turnbull's blue are the same. The failures include the distinction between low-spin FeII and high-spin FeIIIcations in Berlin green. The pitfalls include many, sometimes poorly determined, hyperfine parameters that have been reported for complexes whose stoichiometry is either unknown or unspecified and even sometimes incorrect. [less ▲]

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See detailPIXE Analysis for the pigment identification in the Nizet manucript (18th century)
Machowski, Mélanie ULg; Calvo Del Castillo, Helena ULg; Oger, Cécile ULg et al

Poster (2013, September)

Written in 1740, the Nizet Manuscript is a heraldry book compiling the genealogy of the Nizet family (Verviers, Belgium). It presents a large number of hand-painted heraldries in traditional heraldic ... [more ▼]

Written in 1740, the Nizet Manuscript is a heraldry book compiling the genealogy of the Nizet family (Verviers, Belgium). It presents a large number of hand-painted heraldries in traditional heraldic colours; the gold- and silver-like colours have undergone alteration and induced the degradation of the paper. The first inspection of the book with a binocular lens and UV-visible spectroscopy has led to the selection of representative points to be studied by PIXE analysis for the different groups of pigments. The PIXE measurements have been conducted with the cyclotron of the Institute of Nuclear and Atomic Physics and of Spectrometry of the University of Liege. Some pigments have been clearly identified, such as vermillion, umber or brass, while the presence of some others needs to be confirmed, for example azurite or lapis-lazuli. In the case of the green pigments and the organic ones (red, pink and black colours), the PIXE results must be completed by a molecular analysis. In order to exactly identify all the pigments, Raman analyses will be done to complete the pigment identification of the Nizet Manuscript. [less ▲]

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See detailPIXE identification of the provenance of ferruginous rocks used by Neanderthals
Mathis, François ULg; Bodu, Pierre; Dubreuil, Olivier ULg et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (in press)

Les Bossats, near Ormesson, France, is a newly discovered late Mousterian open air site dated to around 47,000 years ago by thermoluminescence. The archaeological level, fossilized by loess, revealed a ... [more ▼]

Les Bossats, near Ormesson, France, is a newly discovered late Mousterian open air site dated to around 47,000 years ago by thermoluminescence. The archaeological level, fossilized by loess, revealed a rich industry based on the discoid mode, associated with numerous fragments of red and yellow iron oxide-rich rocks showing clear traces of powder production (abrasion, striation, scraping), which are exceptional remains for this remote period. Archeological material and geological samples from the close environment were studied by PIXE and by petrographical observations made on thin sections. The geological sources were identified by means of PIXE analyses on two IBA facilities: AGLAE (2 MV tandem) at the C2RMF in Paris and the cyclotron of the IPNAS (University of Liège). We paid particular attention to the comparison of results obtained on both installations by using the same set of geological standards and by a fine evaluation of the limit of detection relative to each trace elements of interest for both experimental set ups. The elemental fingerprint of one geological source of iron-rich concretions corresponds clearly with the archaeological collection. At least, this investigation demonstrates that the colouring materials were minutely selected in the close neighbouring of the site by the Neanderthals. [less ▲]

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See detailPIXE-identification of pigments used in old masters paintings : Black chalk used as a pigment in an oil painting attributed to Lambert Lombard (Liège 1506-1566)
Oger, Cécile ULg; Allart, Dominique ULg; Weber, Georges ULg

in Proceedings of Art 2002 7th International Conference on "Non-destructive Testing and Microanalysis for the Diagnostics and Conservation of the Cultural and Environmental Heritage" (2002)

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See detailPIXE-PIGE analysis of early medieval window glass from the abbey of Stavelot
Van Wersch, Line ULg; Mathis, François ULg; Biron, Isabelle et al

Poster (2013)

From the 1 st century, glass found in northern Europe was made from a mix of sand and natron that had to be imported from eastern Mediterranean [1]. After the fall of the Roman Empire, glassmakers could ... [more ▼]

From the 1 st century, glass found in northern Europe was made from a mix of sand and natron that had to be imported from eastern Mediterranean [1]. After the fall of the Roman Empire, glassmakers could either recycle existing glass or continue to import material. Then, around the end of the 8 th century, the first testimonies of potash glass, made with sand and trees ashes, are attested [1]. This type of glass would then prevail but the reasons and mechanisms of its appearance remain beyond understanding. They could be linked to the development of architecture and the growing needs of window glass. Founded in the middle of the VII th century, the abbey of Stavelot was a first time ruined by Vikings in 881. In the destruction levels, hundreds fragments of window glass were found [2]. 34 fragments were analysed in PIXE-PIGE at the cyclotron of the Institute of Nuclear and Atomic Physics and of Spectrometry of the University of Liège. The results show coexistence of both natron and potash glass on the site, even in the same archaeological contexts. For the coloration, the recipes to obtain turquoise or amber glass were comparable to those known on other early medieval sites [3], but to make green potash glass the artisans have used to two types of recipes. This shows the need to carry on researches and analysis on early medieval window glass in order to understand its production techniques that are also at the origin of famous gothic stained glass [less ▲]

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See detailPixel-Level Fusion Using Interest Images
Delanoy, Richard L.; Verly, Jacques ULg; Dudgeon, Dan E.

Conference (1991, April)

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