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See detailPiroxicam fails to reduce myocellular enzyme leakage and delayed onset muscle soreness induced by isokinetic eccentric exercise
Croisier, Jean-Louis ULg; Camus, Gérard; Deby-Dupont, G. et al

in Pflügers Archiv : European Journal of Physiology (1996), 431

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See detailPiroxicam fails to reduce myocellular enzyme leakage and delayed onset muscle soreness induced by isokinetic eccentric exercise.
Croisier, Jean-Louis ULg; Camus, G.; Monfils, T. et al

in Mediators of Inflammation (1996), 5(3), 230-4

To test the hypothesis that delayed onset muscular soreness (DOMS) following intense eccentric muscle contraction could be due to increased production of prostaglandin E(2) (PGE(2)), ten healthy male ... [more ▼]

To test the hypothesis that delayed onset muscular soreness (DOMS) following intense eccentric muscle contraction could be due to increased production of prostaglandin E(2) (PGE(2)), ten healthy male subjects were studied. Using a double-blind randomized crossover design, each subject performed two isokinetic tests separated by a period of at least 6 weeks: once with placebo, and once with piroxicam (Feldene((R))). They were given one capsule containing either placebo or piroxicam (20 mg) per day for 6 days with initial doses given starting 3 days prior to isokinetic testing. Exercise consisted of eight stages of five maximal contractions of the knee extensor and flexor muscle groups of both legs separated by 1 min rest phases, on a Kin Trex device at 60( degrees )/s angular velocity. The subjective presence and intensity of DOMS were evaluated using a visual analogue scale immediately after, and 24 and 48 h after each test. The mean plasma concentration of PGE(2) measured at rest and after exercise was significantly lower in the group treated with piroxicam (p < 0.05). However, statistical analysis (two-way ANOVA test) revealed that exercise did not cause any significant change of mean plasma PGE(2) over time in either of the two groups. Eccentric work was followed by severe muscle pain in extensor and flexor muscle groups. Maximal soreness was noted 48 h postexercise. Serum creatine kinase activity and the serum concentration of myoglobin increased significantly, and reached peak values 48 h after exercise in both experimental conditions (p < 0.001). By paired t-test, it appeared that there were no significant differences in the serum levels of these two markers of muscle damage between the two groups at any time point. We conclude that: (1) oral administration of piroxicam fails to reduce muscle damage and DOMS caused by strenuous eccentric exercise; and (2) the hypothetical role of increased PGE(2) production in eccentric exercise-induced muscle damage, DOMS, and reduced isokinetic performance is not substantiated by the present results. [less ▲]

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See detailPiroxicam-Beta-Cyclodextrin in the Treatment of Acute Pain of Rheumatic Disease
Reginster, Jean-Yves ULg; Franchimont, P.

in European Journal of Rheumatology and Inflammation (1993), 12(4), 38-46

Analgesics continue to be the mainstay of therapy in osteoarthritis. Non-steroidal anti-inflammatory drugs (NSAIDs) play an important role, particularly where there is a significant inflammatory component ... [more ▼]

Analgesics continue to be the mainstay of therapy in osteoarthritis. Non-steroidal anti-inflammatory drugs (NSAIDs) play an important role, particularly where there is a significant inflammatory component to the osteoarthritis. Piroxicam-beta-cyclodextrin (PBC) is a new formulation in which piroxicam has been complexed with beta-cyclodextrin, a cyclic oligosaccharide. This results in an increase in the rate of absorption of the active compound and, consequently, in an earlier onset of analgesic action. PBC, like piroxicam, is administered once daily. PBC has been used in the treatment of osteoarthritis. In comparison with piroxicam, PBC showed a more rapid analgesic-anti-inflammatory action after the first administration in patients with active osteoarthritis. Subsequent evaluations at the second, fifth and last day of treatment demonstrated a comparable efficacy of the two drugs. The efficacy and tolerability of PBC was compared with other NSAIDs given intramuscularly, such as diclofenac and ketoprofen. The three compounds provided marked pain relief within thirty minutes and this increased progressively until the third to fourth hour. The efficacy of oral PBC was comparable to that of intramuscular diclofenac or ketoprofen. In comparison with metamisole PBC achieved a more rapid and sustained reduction in pain intensity during the first twelve hours of treatment. This rapid and marked reduction in pain intensity with PBC was also observed in patients with low-back pain when compared with etodolac. In view of its efficacy, tolerability and rapid onset of action, piroxicam-beta-cyclodextrin appears to be an useful analgesic and a prominent progress in the treatment of acute rheumatic pain. [less ▲]

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See detailPISA 2000 : lire ou ne pas lire : état de la question
Lafontaine, Dominique ULg; Vanhulle, Sabine

Report (2002)

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See detailPISA 2003 : au-delà des moyennes, des constats qui forcent à l'action
Baye, Ariane ULg; Demonty, Isabelle ULg; Fagnant, Annick ULg et al

in Les infos de l'Agers - Tables rondes (2005), 1

Detailed reference viewed: 37 (9 ULg)
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See detailPISA 2003 : Quels défis pour notre système éducatif ?
Baye, Ariane ULg; Demonty, Isabelle ULg; Fagnant, Annick ULg et al

E-print/Working paper (2004)

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See detailPISA 2003 Data Analysis Manual : sas users
Monseur, Christian ULg; OECD

Book published by OECD (2005)

Detailed reference viewed: 38 (4 ULg)
See detailPISA 2003 Data Analysis Manual : spss users
Monseur, Christian ULg; OECD

Book published by OECD (2005)

Detailed reference viewed: 47 (9 ULg)
See detailPISA 2006. Exemples de questions de culture scientifique
Baye, Ariane ULg; Quittre, Valérie ULg; Hindryckx, Geneviève ULg et al

E-print/Working paper (2008)

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See detailPisa : au-delà des moyennes, des constats qui forcent à l’action
Baye, Ariane ULg

Conference given outside the academic context (2005)

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See detailPISA : une enquête en suspicion légitime
Dumortier, Jean-Louis ULg

in Lettre de la DFLM (2002), 30

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See detailPISA Data Analysis Manual : spss second edition
Monseur, Christian ULg; OECD

Book published by OECD (2009)

Detailed reference viewed: 20 (2 ULg)
See detailPISA Student Non Response Adjustment Procedures
Rust, K.; Krawchuk, S.; Monseur, Christian ULg

in Prenzel, M.; Kobarg, M.; Schöps, S. (Eds.) et al Research in the context of Programme for International Student Assessment (2012)

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Peer Reviewed
See detailPISA Student Non Response Adjustment Procedures
Rust, K.; Krawchuk, S.; Monseur, Christian ULg

Conference (2009, September)

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See detailPISA test format assessment and the local independence assumption
Monseur, Christian ULg; Baye, Ariane ULg; Lafontaine, Dominique ULg et al

in Ieri Monographs Series. Issues and Methodologies in Large-Scale assessments. (2011), 4

Detailed reference viewed: 121 (14 ULg)
Peer Reviewed
See detailPISA, a powerful tool to foster literacy development.
Lafontaine, Dominique ULg

Conference (2003, January 10)

Detailed reference viewed: 14 (2 ULg)