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See detailPigtailed macaques (Macaca nemestrina leonina): the pest and the gardener
Huynen, Marie-Claude ULg; Albert, Aurélie; Savini, Tommaso ULg

Conference (2010, July)

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See detailPiles à combustible : situation actuelle et perspectives
Job, Nathalie ULg

Conference (2010, May 27)

Detailed reference viewed: 20 (5 ULg)
See detailPiles à combustible: vers une solution économiquement viable
Job, Nathalie ULg

Conference given outside the academic context (2013)

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See detailPilgrimage Certificates from the Mamluk Period: New Data
Bauden, Frédéric ULg

in Bulletin of the School of Oriental and African Studies (in press)

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See detailPilgrimage out of Dispossession
Pagnoulle, Christine ULg

in Commonwealth : Essays and Studies (1994), 17(1), 100-106

Goodison's poems testify to her proud self-assertion, both as woman and as a descendant of African slaves.

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See detailPili genes pattern in Group B streptococci from newborn infections and pregnant women in Europe (DEVANI Project)
Imperi, Monica; Rinaudo, Daniela; Creti, Roberta et al

Poster (2011, September)

Objectives Evaluation of the presence and expression of genes coding for pili in a collection of group B streptococcci (GBS) isolated from newborn infection and pregnant women in the course of the DEVANI ... [more ▼]

Objectives Evaluation of the presence and expression of genes coding for pili in a collection of group B streptococcci (GBS) isolated from newborn infection and pregnant women in the course of the DEVANI (Design of a Vaccine Against Neonatal Infection) project. Methods GBS isolates from pregnant women (PW) and cases of newborn infection (NI) were collected in 8 European countries (Belgium, Bulgaria, Czech Republic, Denmark, Germany, Italy, Spain, United Kingdom) during 2009/10 under the auspices of DEVANI. Total no. of strains examined was 1078 and 192 from PW and NI, respectively. Isolates were screened by multiplex PCR and FACS analysis to evaluate respectively gene presence and surface-exposure of pili. Results The most common gene patterns found were PI-2a alone, PI 1+2a and PI 1+2b, while the PI-2b gene alone was very rare. The most prominent result was that a majority of isolates from NI carried the PI-1+2b gene pattern, while the most common pattern among PW was PI-1+2a. Most of analyzed strains express at least one pilus on their surface. Conclusions All isolates contained at least one gene coding for pili. When present pili 2a and 2b were highly surface exposed. [less ▲]

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See detailLes piliers en céramique.
Mainjot, Amélie ULg; Legros, Caroline ULg; Van Heusden, Alain ULg

in Revue Belge de Médecine Dentaire = Belgisch Tijdschrift voor Tandheelkunde (2006), 61(2), 96-108

As a result of ceramics and all-ceram technologies development esthetic inlay core and abutments flooded the market. Their tooth-colored appearance enhances restoration biomimetism principally on the ... [more ▼]

As a result of ceramics and all-ceram technologies development esthetic inlay core and abutments flooded the market. Their tooth-colored appearance enhances restoration biomimetism principally on the marginal gingiva area. This article reviews indications and types of cores designed for natural teeth and implants. [less ▲]

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See detailLe pilomatricome unique ou multifocal et son pendant malin.
Reginster, Marie-Annick ULg; Quatresooz, Pascale ULg; Franchimont, Claudine ULg et al

in Dermatologie Actualité (2010), 121

Detailed reference viewed: 53 (1 ULg)
See detailPilootproject : ontslagmanagement in Belgische ziekenhuizen. [Pilot study : discharge management in Belgian hospitals]. Final report, 2000
Abraham, I; Bollen, S; de Froidmont, C et al

Report (2000)

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See detailA pilot double-blind randomized placebo-controlled study of molsidomine 16 mg once-a-day in patients suffering from stable angina pectoris: correlation between efficacy and over time plasma concentrations
Messin, R.; Fenyvesi, T.; Carreer-Bruhwyler, F. et al

in European Journal of Clinical Pharmacology (2003), 59(3), 227-232

Objectives. A new once-a-day (o.a.d.) formulation of molsidomine (16 mg) was evaluated in patients with stable angina pectoris. The aims were to characterize its pharmacokinetics after a single dose, to ... [more ▼]

Objectives. A new once-a-day (o.a.d.) formulation of molsidomine (16 mg) was evaluated in patients with stable angina pectoris. The aims were to characterize its pharmacokinetics after a single dose, to demonstrate its clinical efficacy and safety versus placebo and to investigate correlations between pharmacokinetics and pharmacodynamics. Methods. Forty-two patients were recruited in a double-blind, crossover, randomized placebo-controlled trial. The pharmacokinetics of molsidomine and SIN-1, its active metabolite, were determined at specific time points (3, 6, 10, 14, 18, 22 and 24 h) after the administration of a single dose of molsidomine 16 mg o.a.d. in all patients distributed into seven groups. Twenty-eight of these 42 patients showed a positive baseline cycloergometric exercise test response during the run-in placebo period and were used to compare the efficacy of molsidomine to placebo. Relationships between plasma concentration in molsidomine or SIN-1 and ischemic threshold were assessed in 16 of the 28 patients with a positive exercise test at baseline. Indeed, the censored variable ischemia-limited tolerance to exercise could not be evaluated in those patients who did not show exercise-induced ischemia anymore under molsidomine 16 mg o.a.d. Pharmacokinetic-pharmacodynamic relationships were evaluated using regression models and correlation coefficients. Results. The highest average concentration in molsidomine and SIN-1 occurred after 6 h, then a plateau of 15-20 ng/ml molsidomine and 0.8-3.0 ng/ml SIN-1 was maintained for at least 8 h and the mean residual molsidomine concentration 24 h post-drug intake was around 8 ng/ml, still in the effective range of 5-10 ng/ml. A significant increase in total workload (+52 W min, P=0.009), total exercise time (+32 s, P=0.003) and time to angina (+25 s, P=0.016) was measured with molsidomine 16 mg o.a.d. relative to placebo. Using linear regression, significant correlation coefficients were determined between molsidomine plasma concentrations (but not SIN-1) and exercise test improvements (r=0.827, P<0.001 for the total workload; r=0.772, P<0.001 for the total exercise time; and r=0.566, P=0.028 for the time to 1 mm ST-segment depression). Conclusion. The pharmacokinetics of molsidomine 16 mg in patients with stable angina pectoris is compatible with a o.a.d. dosage regimen. This o.a.d. formulation is effective and well-tolerated, providing a 24-h therapeutic control of myocardial ischemia. A positive and significant linear relationship between molsidomine plasma concentration and the increase in exercise tolerance was observed. [less ▲]

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See detailPILOT PROJECT IN CHR-LIEGE: INVITING SIBLINGS OF CHILDREN WITH CANCER TO A CREATIVE AND EXPRESSIVE WEEK-END WITH PSYCHOLOGISTS AND ONCOLOGIST
Forget, Patricia; Badot, Isabelle; Missotten, Pierre ULg et al

Poster (2013, September 27)

The siblings week end with the psycho-medical team was highly successful It opens another way to improve the care of the siblings Questionnary forms should be developped in the future to evaluate the real ... [more ▼]

The siblings week end with the psycho-medical team was highly successful It opens another way to improve the care of the siblings Questionnary forms should be developped in the future to evaluate the real psychological impact [less ▲]

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See detailPilot project « Walphy » : Walloon experimentation of river restoration
Peeters, Alexandre ULg; Verniers, Gisèle; de le Court, Bernard et al

Conference (2012, April 20)

According to the Water Framework Directive (WFD 2000/60), our rivers and water bodies are required to achieve the “good ecological status” by 2015. This requirement is related to the physico-chemical ... [more ▼]

According to the Water Framework Directive (WFD 2000/60), our rivers and water bodies are required to achieve the “good ecological status” by 2015. This requirement is related to the physico-chemical, biological water quality as well as the hydromorphological quality. In this context, a LIFE Environment project, co-founded by the European Union and the Service Publique de Wallonie, was launched in 2009 for a period of five years. It aims to realize the experimental and demonstrative river restoration works on three “at risk” water bodies, based on two axes: longitudinal continuity and transversal continuity. The first two selected water bodies (Bocq, eastern tributary of the Meuse) are suitable for the restoration works which concern the longitudinal continuity due to the presence of dams and other obstacles between 1 and 3 m high. These works consist in dam management (weir removal or fish ladders) taking into account hydromorphological (bedload transport) and biological (invertebrate or fish species free movement) impacts. The third water body (Eau Blanche, western tributary of the Meuse) presents straightened rivers with artificial banks which consequently lead to poor connections between the stream and its floodplain. This water body is therefore appropriated for the works based on the transversal continuity recovery. These works consist in enhancing straightened river channel and restoring meanders or banks. Until now, these works have been realized on more than 5 km. These works are being monitored on the basis of geomorphological and ecological analysis. The geomorphological monitoring is based on surveys conducted before and after the works. It concerns the bedload transport, the clogging of the gravel layer and the morphological changes of the river following the works. The ecological monitoring is based on two indicators: macroinvertebrates and fishes. Standardized and repeatable methods were developed to compare the situation before and after the works, especially through the analysis of microhabitats. In addition, we use another two complementary indexes of physical quality for this monitoring. Developed by the consulting office Teleos, these indexes have a fish orientation and have been implemented in many of our stations. [less ▲]

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See detailPILOT PROJECT « WALPHY »: WALLOON EXPERIMENTATION OF RIVER RESTORATION
Peeters, Alexandre ULg; Verniers, Gisèle; de le Court, Bernard et al

Poster (2013, March 13)

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See detailPilot proof of concept clinical trials of Stochastic Targeted (STAR) glycemic control.
Evans, Alicia; Shaw, Geoffrey M; Le Compte, Aaron et al

in Annals of intensive care (2011), 1

ABSTRACT: INTRODUCTION: Tight glycemic control (TGC) has shown benefits but has been difficult to achieve consistently. STAR (Stochastic TARgeted) is a flexible, model-based TGC approach directly ... [more ▼]

ABSTRACT: INTRODUCTION: Tight glycemic control (TGC) has shown benefits but has been difficult to achieve consistently. STAR (Stochastic TARgeted) is a flexible, model-based TGC approach directly accounting for intra- and inter- patient variability with a stochastically derived maximum 5% risk of blood glucose (BG) < 4.0 mmol/L. This research assesses the safety, efficacy, and clinical burden of a STAR TGC controller modulating both insulin and nutrition inputs in pilot trials. METHODS: Seven patients covering 660 hours. Insulin and nutrition interventions are given 1-3 hourly as chosen by the nurse to allow them to manage workload. Interventions are calculated by using clinically validated computer models of human metabolism and its variability in critical illness to maximize the overlap of the model-predicted (5-95th percentile) range of BG outcomes with the 4.0-6.5 mmol/L band while ensuring a maximum 5% risk of BG < 4.0 mmol/L. Carbohydrate intake (all sources) was selected to maximize intake up to 100% of SCCM/ACCP goal (25 kg/kcal/h). Maximum insulin doses and dose changes were limited for safety. Measurements were made with glucometers. Results are compared to those for the SPRINT study, which reduced mortality 25-40% for length of stay >/=3 days. Written informed consent was obtained for all patients, and approval was granted by the NZ Upper South A Regional Ethics Committee. RESULTS: A total of 402 measurements were taken over 660 hours (~14/day), because nurses showed a preference for 2-hourly measurements. Median [interquartile range, (IQR)] cohort BG was 5.9 mmol/L [5.2-6.8]. Overall, 63.2%, 75.9%, and 89.8% of measurements were in the 4.0-6.5, 4.0-7.0, and 4.0-8.0 mmol/L bands. There were no hypoglycemic events (BG < 2.2 mmol/L), and the minimum BG was 3.5 mmol/L with 4.5% < 4.4 mmol/L. Per patient, the median [IQR] hours of TGC was 92 h [29-113] using 53 [19-62] measurements (median, ~13/day). Median [IQR] results: BG, 5.9 mmol/L [5.8-6.3]; carbohydrate nutrition, 6.8 g/h [5.5-8.7] (~70% goal feed median); insulin, 2.5 U/h [0.1-5.1]. All patients achieved BG < 6.1 mmol/L. These results match or exceed SPRINT and clinical workload is reduced more than 20%. CONCLUSIONS: STAR TGC modulating insulin and nutrition inputs provided very tight control with minimal variability by managing intra- and inter- patient variability. Performance and safety exceed that of SPRINT, which reduced mortality and cost in the Christchurch ICU. The use of glucometers did not appear to impact the quality of TGC. Finally, clinical workload was self-managed and reduced 20% compared with SPRINT. [less ▲]

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See detailPilot scale biotransformation of vegetal oil into natural green note flavor using sugar beet leaves as sources of hydroperoxide lyase
Gigot, Cédric ULg; Ongena, Marc ULg; Fauconnier, Marie-Laure ULg et al

Poster (2009, June 02)

Natural green note aromas (GLVs) are highly attractive flavors commonly used in the food industry. These are produced in extremely low levels upon physiological stress in plant organs of any sort. This ... [more ▼]

Natural green note aromas (GLVs) are highly attractive flavors commonly used in the food industry. These are produced in extremely low levels upon physiological stress in plant organs of any sort. This weak sporadic presence entails a very expensive extraction step to obtain pure GLVs. Therefore catalytic biotransformations of fatty acid sources, the initial substrate for GLVs, have been developed. Enzymatic defense pathways and particularly the LOX pathway produce the major part of GLVs. Unlike GLV molecules that are emitted in the atmosphere, the enzymes are extractible from the plant material. Thus, a combination of plant enzyme extracts and substrate preparations provides all the ingredients for GLV production. Besides, sugar beet leaves present high levels of hydroperoxide lyase among plant sources and are available in large amounts during three months. In this enzymatic pathway, fatty acids are successively transformed by lipase, lipoxygenase and hydroperoxide lyase into aldehydes and alcohols, final compounds of GLVs pathway. Limiting and problematic steps occur with the action of hydroperoxide lyase, when enzymatic catalysis is followed by an enzyme destabilization. Alternative substrates bind irreversibly to the heme group of the enzyme and end the reaction. This poster briefly describes the development of a complete bioprocess for natural GLV production, from hydrolysis to purification. A high level of biotransformation could be achieved using optimum experimental conditions and a cheap source of plant materials. [less ▲]

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See detailThe pilot study on clinical presentation of pituitary adenomas in patients with multiple endocrine neoplasia type I (MEN1) phenotype with and without MEN1 mutation
Rostomyan, Liliya ULg; TICHOMIROWA, M; KIRDYANKINA, N et al

in Endocrine abstracts - May 2012, volume 29 (2012, May)

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