Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Peer Reviewed
See detailMissa pro defunctis – Gilles Hayne (1590-1650)
Corswarem, Emilie ULg

Conference (2006, July 27)

Detailed reference viewed: 31 (0 ULg)
Full Text
Peer Reviewed
See detailA missense mutation accelerating the gating of the lysosomal Cl-/H+-exchanger ClC-7/Ostm1 causes osteopetrosis with gingival hamartomas in cattle.
Sartelet, Arnaud ULg; Stauber, Tobias; Coppieters, Wouter ULg et al

in Disease Models & Mechanisms (2014), 7

Chloride/proton exchange by the lysosomal anion transporter ClC-7/Ostm1 is of pivotal importance for the physiology of lysosomes and bone resorption. Mice lacking either ClC-7 or Ostm1 develop a lysosomal ... [more ▼]

Chloride/proton exchange by the lysosomal anion transporter ClC-7/Ostm1 is of pivotal importance for the physiology of lysosomes and bone resorption. Mice lacking either ClC-7 or Ostm1 develop a lysosomal storage disease and mutations in either protein have been found to underlie osteopetrosis in mice and humans. Some human disease-causing CLCN7 mutations accelerate the usually slow voltage-dependent gating of ClC-7/Ostm1. However, it has remained unclear whether the fastened kinetics is indeed causative for the disease. Here we identified and characterized a new deleterious ClC-7 mutation in Belgian Blue Cattle with a severe symptomatology including peri-natal lethality and in most cases gingival hamartomas. By autozygosity mapping and genome-wide sequencing we found a handful of candidate variants, including a cluster of three private SNPs causing the substitution of a conserved tyrosine in the CBS2 domain of ClC-7 by glutamine. The case for ClC-7 was strengthened by subsequent examination of affected calves that revealed severe osteopetrosis. The Y750Q mutation largely preserved the lysosomal localization and assembly of ClC-7/Ostm1, but drastically accelerated its activation by membrane depolarization. These data provide first evidence that accelerated ClC-7/Ostm1 gating per se is deleterious, highlighting a physiological importance of the slow voltage-activation of ClC-7/Ostm1 in lysosomal function and bone resorption. [less ▲]

Detailed reference viewed: 53 (6 ULg)
Full Text
See detailA missense mutation in the ClC-7 chloride channel causes hamartomas with osteopetrosis in cattle.
Sartelet, Arnaud ULg; Stauber, Tobias; Druet, Tom ULg et al

Conference (2012, June 05)

Detailed reference viewed: 25 (5 ULg)
Full Text
See detailA missense mutation in the ClC-7 chloride channel causes hamartomas with osteopetrosis in cattle.
Sartelet, Arnaud ULg; Stauber, Tobias; Coppieters, Wouter ULg et al

Conference (2012, October 19)

Detailed reference viewed: 54 (15 ULg)
See detailThe Missing Chapter in Janet Frame's 'Living in the Maniototo'
Delrez, Marc ULg

Conference (2005, March 23)

Detailed reference viewed: 7 (1 ULg)
Full Text
Peer Reviewed
See detailThe Missing Chapter in Janet Frame's Living in the Maniototo
Delrez, Marc ULg

in Journal of New Zealand Literature (2006), 24(1), 73-93

Detailed reference viewed: 40 (11 ULg)
Full Text
Peer Reviewed
See detailThe missing opacity and the temperature calibration of solar-type stars
Magain, Pierre ULg

in Astronomy and Astrophysics (1987), 181

The novel temperature calibration of some color indices presented for G and F dwarfs is based on the IR flux method and extends the work of Saxner and Hammarback (1985) to the Population II stars ... [more ▼]

The novel temperature calibration of some color indices presented for G and F dwarfs is based on the IR flux method and extends the work of Saxner and Hammarback (1985) to the Population II stars. Attention is given to the discrepancy between theoretical and empirical temperature calibrations. It is suggested that the most straightforward interpretation of the disagreement between empirical colors and some model predictions is that of the 'missing opacity' due to a veil of faint metal lines, present in the blue and UV regions of the spectra of solar-type and cooler stars, but excluded from the model. [less ▲]

Detailed reference viewed: 19 (0 ULg)
See detailThe missing piece of the jigsaw: the Middle and Upper Palaeolithic of Central Asia
Flas, Damien ULg

Scientific conference (2014, October 14)

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailThe missing UV opacity and the colours of solar-type stars
Magain, Pierre ULg

in Astronomy and Astrophysics (1983), 122

A simple method is proposed to take into account the "missing UV opacity" in solar-type stars. It is shown that the mere inclusion of that UV opacity through a very simple formula is sufficient to bring ... [more ▼]

A simple method is proposed to take into account the "missing UV opacity" in solar-type stars. It is shown that the mere inclusion of that UV opacity through a very simple formula is sufficient to bring the theoretical colours in agreement with observed ones for stars of different metal abundances and belonging to the spectral range from mid-F to late-G. Synthetic colours computed in the Geneva and UBV systems reproduce the various observed relations satisfactorily. The relations based on these colours allow reliable estimates of effective temperatures, surface gravities and metal abundances of stars. In addition, solar colours are obtained and three more solar twin candidates are proposed. [less ▲]

Detailed reference viewed: 15 (1 ULg)
See detailLa mission belge en Mongolie
Kurth, Godefroid ULg

in Almanach belge illustré (1884)

Detailed reference viewed: 10 (0 ULg)
Full Text
See detailMission d'évaluation de l'exposition permanente du Musée de la Cour d'Or à Metz
Drouguet, Noémie ULg; Chaumier, Serge

Report (2012)

Detailed reference viewed: 15 (1 ULg)
See detailMission d'évaluation de la situation du patrimoine culturel en Moldavie, rapport d'évaluation technique
Duperroy, Francoise ULg; MIRCEA, ANGELESCU; Goven, François

Report (2012)

table des matières constat de la situation 1. un Patrimoine important et varié mais menacé 2. une conception du patrimoine ambitieuse mais parfois restrictive 3. Un cadre réglementaire existant, mais de ... [more ▼]

table des matières constat de la situation 1. un Patrimoine important et varié mais menacé 2. une conception du patrimoine ambitieuse mais parfois restrictive 3. Un cadre réglementaire existant, mais de réelles difficultés de coordination 4. des équipes motivées mais aux effectifs peu nombreux 5. la volonté politique réelle de quelques-uns, mais un contexte particulièrement contraint 6. une société civile active et pleine d'attente 7. une besoin manifeste en matière de formation III. Propositions 1. définir le patrimoine moldave 2. des outils de protection performants 3. améliorer le fonctionnement de l'administration 4. sensibiliser la société civile 5. mettre en place un dispositif de formation ou aides [less ▲]

Detailed reference viewed: 29 (1 ULg)
See detailMission d'expertise
Cornet, Annie ULg

Diverse speeche and writing (2013)

Detailed reference viewed: 4 (0 ULg)
Full Text
See detailMission d'expertise dans le cadre de l'élaboration du Plan Jeunesse de la Fédération Wallonie-Bruxelles
Guillaume, Jean-François ULg; Fournier, Bernard

Report (2013)

Ce rapport présente les données collectées auprès des promoteurs d'initiatives locales prises dans le cadre d'une politique intégrée de jeunesse, ainsi qu'une analyse qualitative. Les opérateurs ... [more ▼]

Ce rapport présente les données collectées auprès des promoteurs d'initiatives locales prises dans le cadre d'une politique intégrée de jeunesse, ainsi qu'une analyse qualitative. Les opérateurs rencontrés sont actifs sur le territoire de la région bilingue de Bruxelles-capitale et sur le territoire de la région de langue française. Ce rapport présente les obstacles et les contraintes qui pèsent sur la mise en oeuvre d'une approche intégrée, les attentes des professionnels en charge de ces dispositifs et les modalités possibles pour un travail en coordination et/ou en partenariat. [less ▲]

Detailed reference viewed: 20 (0 ULg)
See detailMission d'expertise scientifique
Cornet, Annie ULg

Diverse speeche and writing (2013)

Detailed reference viewed: 5 (0 ULg)