Short-term effects of an organochloride pesticide (endosulfan) on amphibian tadpoles; Brasseur, Catherine ; et alPoster (2010) Detailed reference viewed: 37 (7 ULg) Short-term effects of spermine ingestion on the small intestine: a comparison of suckling and weaned ratsPeulen, Olivier ; ; Dandrifosse, Guy ![]() in Reproduction Nutrition Development (2004), 44(4, Jul-Aug), 353-364 We have previously shown that spermine, shortly after its ingestion, can induce the alteration of the morphology of the small intestine of suckling rats. It was proposed that this alteration is due to ... [more ▼] We have previously shown that spermine, shortly after its ingestion, can induce the alteration of the morphology of the small intestine of suckling rats. It was proposed that this alteration is due to polyamine accumulation inside the epithelial cells. This could also be related to the fact that the intestine of the suckling rat is in an immature state. To shed light on this issue, disaccharidase and alkaline phosphatase activity assays, protein, DNA and RNA content measurements and polyamine concentration analysis were performed on the small intestine of suckling and weaned Wistar rats treated with spermine. Spermine did not induce the same intestinal alterations in weaned rats compared to suckling animals. Indeed, in sucklings, spermine administration induced a decrease of the protein, DNA, putrescine and spermidine intestinal content, suggesting a cell loss. The cell loss impaired the activity of intestinal enzymes: lactase, maltase and alkaline phosphatase. In weaned rats, the same treatment did not alter these parameters. Exogenous spermine by itself is not sufficient to induce the alterations described here and previously. The maturity degree of the small intestine could be the basis of this process. [less ▲] Detailed reference viewed: 11 (0 ULg) Short-term memory and the left intraparietal sulcus: Focus of attention? Further evidence from a face short-term memory paradigmMajerus, Steve ; Bastin, Christine ; Poncelet, Martine et alin NeuroImage (2007), 35(1), 353-367 This study explored the validity of an attentional account for the involvement of the left intraparietal sulcus (IPS) in visual STM tasks. This account considers that during STM tasks, the IPS acts as an ... [more ▼] This study explored the validity of an attentional account for the involvement of the left intraparietal sulcus (IPS) in visual STM tasks. This account considers that during STM tasks, the IPS acts as an attentional modulator, maintaining activation in long-term memory networks that underlie the initial perception and processing of the specific information to be retained. In a recognition STM paradigm, we presented sequences of unfamiliar faces and instructed the participants to remember different types of information: either the identity of the faces or their order of presentation. We hypothesized that, if the left IPS acts as an attentional modulator, it should be active in both conditions, but connected to different neural networks specialized in serial order or face identity processing. Our results showed that the left IPS was activated during both order and identity encoding conditions, but for different reasons. During order encoding, the left IPS showed functional connectivity with order processing areas in the right IPS, bilateral premotor and cerebellar cortices, reproducing earlier results obtained in a verbal STM experiment. During identity encoding, the left IPS showed preferential functional connectivity with right temporal, inferior parietal and medial frontal areas involved in detailed face processing. These results not only support an attentional account of left IPS involvement in visual STM, but given their similarity with previous results obtained for a verbal STM task, they further highlight the importance of the left IPS as an attentional modulator in a variety of STM tasks. [less ▲] Detailed reference viewed: 102 (29 ULg) Short-term memory, articulation rate and subvocal rehearsal in Down's syndromeComblain, Annick ![]() Poster (1995, May 12) Gathercole (1994) show that in normal young children there is no significant link between articulation rate and immediate memory span, but that these variables are closely related in adults. These results ... [more ▼] Gathercole (1994) show that in normal young children there is no significant link between articulation rate and immediate memory span, but that these variables are closely related in adults. These results are in contradiction with the short-term memory development hypotheses stated by the working memory model. According to these hypotheses, children are sensitive to word-length effect providing that stimuli are presented auditorily. We also know that word-length effect is strongly related to articulation rate and to subvocal rehearsal. This conception of mnemonic development has been recently challenged. Some authors show that, in adults, word-length effect can be a consequence of the delay at recall. According to Gathercole, the same conclusion can be applied to results obtained with children : word-length effect can be due to delay at recall of long words rather than to the utilization of subvocal rehearsal. Previous studies seem to confirm this hypothesis by showing that children are not affected by articulatory suppression. These results have clear implications for the short-term memory development hypothesis. It seems that in spite an strong word-length effect, children do not rehearse during auditory memory span tasks. The following experiments are based: (1) on the assumption that mental retarded individuals do not rehearse and (2) on the highly significant word-length effect in our Down's syndrome subjects. Our hypothesis, as Gathercole's one, is that if subjects really rehearse, then memory span and articulation rate will be highly correlated. [less ▲] Detailed reference viewed: 42 (1 ULg) Short-term optical variability of HD 153919 = 4U1700-37; ; Surdej, Jean et alin Acta Astronomica (1979), 29(4), 481-503 Photometric observations of HD 153919 are presented, which indicate optical cyclic variations with an amplitude of up to 0.02 mag, and a strong dependence of the amplitude on the orbital plane. From power ... [more ▼] Photometric observations of HD 153919 are presented, which indicate optical cyclic variations with an amplitude of up to 0.02 mag, and a strong dependence of the amplitude on the orbital plane. From power spectrum analysis, a value of 99.9 min from the observations of van Paradijs et al. (1978) has been determined for the characteristic period. In addition, evidence suggests a secular decrease of the period with a rate of decrease of -0.03 per year. [less ▲] Detailed reference viewed: 11 (1 ULg) Short-term post-dispersal fate of seeds defecated by two small primate species (Saguinus mystax and Saguinus fuscicollis) in the Amazonian forest of PeruCulot, Laurence ; Huynen, Marie-Claude ; Gérard, Paul et alin Journal of Tropical Ecology (2009), 25 Post-dispersal fate of seeds dispersed by large primates is well studied but little is known about this process in small frugivores like tamarins. This study in the Amazonian forest of Peru aimed at ... [more ▼] Post-dispersal fate of seeds dispersed by large primates is well studied but little is known about this process in small frugivores like tamarins. This study in the Amazonian forest of Peru aimed at investigating if characteristics related to the defecation patterns of tamarins (Saguinus mystax and Saguinus fuscicollis) affected short-term post-dispersal seed fate, through secondary seed dispersal by dung beetles and removal by seed predators. Data on dung beetle activity were based on direct observations of 49 defecations while seed fate was studied using semi-controlled experiments (N = 458 for secondary dispersal and N = 398 for predation). Tamarins produce small defecations with a low number of seeds. Thirty-five per cent of defecations were visited by an average of 1.5 dung beetles that usually transport the faeces as pellets. Twenty-four per cent of seeds were buried by beetles at a mean depth of 3.5 cm. With increasing quantities of faecal matter, the probability of secondary seed dispersal increased but not the depth of burial. Seed predation pressure was low (17.6%) after 4 d and higher in faeces of S. mystax than in faeces of S. fuscicollis. Despite their small size, tamarins could be considered as high-quality seed dispersers, with a potential role for forest regeneration. [less ▲] Detailed reference viewed: 133 (21 ULg) Short-term post-dispersal fate of seeds primarily dispersed by tamarinsCulot, Laurence ![]() Conference (2009, February 25) Detailed reference viewed: 6 (0 ULg) Short-term post-dispersal fate of seeds primarily dispersed by tamarinsCulot, Laurence ![]() Conference (2008, June 09) Detailed reference viewed: 2 (0 ULg) Short-Term Risk Stratification at Admission Based on Simple Clinical Data in Acute Myocardial InfarctionDUBOIS, Christophe ; PIERARD, Luc ; Albert, Adelin et alin American Journal of Cardiology (1988), 61(4), 216-9 Simple clinical data, available in all coronary care units, were recorded in 1,013 consecutive patients with acute myocardial infarction (AMI). In order to identify the patients at highest and lowest risk ... [more ▼] Simple clinical data, available in all coronary care units, were recorded in 1,013 consecutive patients with acute myocardial infarction (AMI). In order to identify the patients at highest and lowest risk of mortality during hospital stay, a prognostic index was established from a stepwise logistic discriminant analysis of 10 clinical variables obtained at admission in a consecutive series of 477 patients hospitalized in 1 of 2 coronary care units admitting new patients on alternate days and treating them similarly. This prognostic index was applied to a comparison group of 536 consecutive patients admitted to the other coronary care unit. In the experimental group, 57 of the 477 patients (12%) died during hospital stay; 60 of the 536 patients (11%) died in the comparison group. As individual variables, age, previous history of AMI, anterior site and left ventricular function on admission were associated with increased mortality. Three variables were selected from the stepwise logistic discriminant analysis of the experimental group: age; site (anterior = 1, other = 0); and grade of left ventricular function (0 to 4). Prognostic index = 5.9019 - 0.8961 function - 0.5708 location - 0.0369 age. This index was validated in the comparison group. Patients were allocated into different classes with increasing index values associated with decreasing risk. Three subgroups of patients were identified: high risk of hospital mortality (index less than or equal to 1; mortality: 51%), intermediate risk (index 1 to 3; mortality: 18%) and low risk (index greater than 3; mortality: 4%). The use of this simple prognostic index may improve clinical management and selection of patients for intervention trials. [less ▲] A short-term run-in study can significantly contribute to increasing the quality of long-term osteoporosis trials. The strontium-ranelate phase 3 programReginster, Jean-Yves ; ; et alin Osteoporosis International (2002), 13(S1), 30 Detailed reference viewed: 5 (1 ULg) Short-term temperature impact on soil heterotrophic respiration in limed agricultural soil samplesBuysse, Pauline ; Goffin, Stéphanie ; Carnol, Monique et alin Biogeochemistry (2013), 112(1-3), 441-455 This study sought to investigate the hourly and daily timescale responses of soil CO2 fluxes to temperature in a limed agricultural soil. Observations from different incubation experiments were compared ... [more ▼] This study sought to investigate the hourly and daily timescale responses of soil CO2 fluxes to temperature in a limed agricultural soil. Observations from different incubation experiments were compared with the results of a model combining biotic (heterotrophic respiration) and abiotic (carbonate weathering) components. Several samples were pre-incubated for 8-9 days at three temperatures (5, 15 and 25°C) and then submitted to short-term temperature cycles (where the temperature was increased from 5 to 35°C in 10°C stages, with each stage being 3 h long). During the temperature cycles (hourly timescale), the soil CO2 fluxes increased significantly with temperature under all pre-incubation temperature treatments. A hysteresis effect and negative fluxes during cooling phases were also systematically observed. At a given hourly timescale temperature, there was a negative relationship of the CO2 fluxes with the pre-incubation temperature. Using the combined model allowed the experimental results to be clearly described, including the negative fluxes and the hysteresis effect, showing the potentially large contribution of abiotic fluxes to total fluxes in limed soils, after short-term temperature changes. The fairly good agreement between the measured and simulated flux results also suggested that the biotic flux temperature sensitivity was probably unaffected by timescale (hourly or daily) or pre-incubation temperature. The negative relationship of the CO2 fluxes with the pre-incubation temperature probably derived from very labile soil carbon depletion, as shown in the simulations. This was not, however, confirmed by soil carbon measurements, which leaves open the possibility of adaptation within the microbial community. [less ▲] Detailed reference viewed: 53 (14 ULg) Short-term temperature impacts on soil CO2 fluxes: An incubation experiment with agricultural soil samples.Buysse, Pauline ; Goffin, Stéphanie ; Carnol, Monique et alin Geophysical Research Abstracts (2010, May 06), 12 Detailed reference viewed: 29 (19 ULg) Short-term temperature impacts on soil respiration.Buysse, Pauline ; Goffin, Stéphanie ; Carnol, Monique et alPoster (2009, June) Despite considerable recent work on soil heterotrophic respiration, a mechanistic understanding of this process is still missing. Temperature is one of the most important driving factors. It can influence ... [more ▼] Despite considerable recent work on soil heterotrophic respiration, a mechanistic understanding of this process is still missing. Temperature is one of the most important driving factors. It can influence the mechanism through multiple ways, whose importance may vary with time. An incubation experiment is set up to study short-term temperature influences on soil microbial respiration and its evolution through time. Soil samples are taken in spring from the surface layer (0-25cm) of a bare agricultural loamy soil situated in Lonzée in Belgium (Hesbaye region) and are homogenized before being placed into incubators at three different temperatures, namely 5, 15 and 25°C. Temperature is regulated by Peltier systems that warm up or cool down a sand bath containing jars with soil samples. Once a week, incubation temperatures are increased and decreased by 5°C-steps, starting from each incubator temperature, to achieve a one-day temperature cycle between 5 and 35°C. CO2 flux measurements are performed at each temperature step by a closed dynamic chamber system, after the temperature has stabilized in the samples. Microbial biomass (C and N) is determined four times during the temperature cycle by the fumigation-extraction technique and soil labile carbon is measured at the beginning of each cycle by the hot-water extraction method. Moisture levels in soil samples are regularly checked and adjusted to keep optimal soil moisture content. Between CO2 flux measurements, jars are left open to ensure that anaerobic conditions do not occur. Further investigations could include an assessment of the importance of substrate availability and depletion on microbial activity, and a model development related to the results provided by this experiment. [less ▲] Detailed reference viewed: 36 (5 ULg) Short-term toxicity of various pharmacological agents on the in vitro nitrification process in a simple closed aquatic system; ; La Duong, Duc et alin Alternatives to Laboratory Animals [= ATLA] (1999), 27 During the treatment of fish diseases, drugs which inhibit the nitrification process can cause acute ammonia toxicity. The same phenomenon can occur when fish are put into a tank without active cultures ... [more ▼] During the treatment of fish diseases, drugs which inhibit the nitrification process can cause acute ammonia toxicity. The same phenomenon can occur when fish are put into a tank without active cultures of nitrifying bacteria. The purpose of this study was to quantify the inhibitory effects of 15 pharmacological agents, which are often used as therapeutic agents in ichthyopathology, on ammonia removal and nitrate production in a simple closed aquatic system. The experiments were conducted in polyethylene bags containing activated biofilters and synthetic water solutions, held in a water bath. Ammonia was added to initiate the nitrification process, and graded concentrations of various pharmacological agents were added. The effects of the pharmacological agents on in vitro nitrification were assessed by monitoring ammonia and nitrate concentrations compared to controls with no added agents, for 24 hours. Graded concentrations of ampicillin (Albipen(R)), chloramine T, enrofloxacin (Baytril(R)), erythromycin, levamisole, methylene blue and polymyxin B induced dose-dependent inhibitions of ammonia removal and nitrate production. The corresponding linear regression curves showed high correlation coefficients and were highly significant (p < 0.05). The addition of chloramphenicol, copper (II) sulphate, kanamycin disulphate, malachite green, neomycin sulphate, potassium penicillin G, tetracycline and a mixture of trimethoprim and sulphadoxin (Duoprim(TM)) had no significant effects on the nitrification process. A significant dose-related inhibition of nitrate production, but not of ammonia oxidation, was observed with enrofloxacin. The significant correlation (r = 0.940; p < 0.001) between the degrees of inhibition of ammonia oxidation and nitrate production for the various inhibitory pharmacological agents has also been calculated, with a view to validating this method. The data presented suggest that separate tank facilities for hospitalisation or quarantine are necessary when treating diseased fish with ampicillin, enrofloxacin, chloramine T, erythromycin, levamisole, methylene blue or polymyxin B, in order to avoid ammonia poisoning. [less ▲] Detailed reference viewed: 128 (4 ULg) Short-term variations of the partial pressure of CO2 in surface waters of the Galician upwelling systemBorges, Alberto ; in Progress in Oceanography (2001), 50(2-4), 283-302 The partial pressure of CO2 (pCO2) and dissolved oxygen saturation level (%O2) were monitored continuously during a cruise in August 1998, which sampled surface waters off the Galician coast. Data are ... [more ▼] The partial pressure of CO2 (pCO2) and dissolved oxygen saturation level (%O2) were monitored continuously during a cruise in August 1998, which sampled surface waters off the Galician coast. Data are presented from two Lagrangian experiments carried out in an upwelling on the continental shelf and in the core of an offshore filament. The data show that daily variations in surface pCO2 and oxygen (%O2) were controlled by the diurnal cycle of primary production/respiration, temperature variations and air–sea exchange. Data obtained during various cross-shelf and cross-filament transects are also discussed and give an insight into the processes controlling large scale variations of pCO2 and %O2 in the Galician upwelling system. These data suggest that upwelling filaments are an important feature of the inorganic carbon cycle of upwelling systems. However more field data in the various eastern boundary current systems worldwide are needed. [less ▲] Detailed reference viewed: 4 (0 ULg) Short-term weather forecasting for solar buildings optimal control : an application of neural networks; Andre, Philippe ; et alin Proceedings Eufit'98 (1998, September) Detailed reference viewed: 16 (1 ULg) Shortened first-line high-dose chemotherapy for patients with poor-prognosis aggressive lymphoma; ; et al in Journal of Clinical Oncology (2002), 20(10), 2472-2479 Purpose: Randomized trial LNH93-3 was conducted on patients who had poor-prognosis aggressive lymphoma and were younger than 60 years with two to three factors of the age-adjusted International Prognostic ... [more ▼] Purpose: Randomized trial LNH93-3 was conducted on patients who had poor-prognosis aggressive lymphoma and were younger than 60 years with two to three factors of the age-adjusted International Prognostic Index to evaluate the benefit of early high-dose therapy (HDT) with autologous stem-cell transplantation (ASCT). Patients and Methods: Patients were randomized between doxorubicin, cyclophosphamide, vindesine, bleomycin, and prednisone (ACVBP) chemotherapy followed by sequential consolidation and an experimental shortened treatment consisting of three cycles with escalated doses of cyclophosphamide, epirubicin, vindesine, bleomycin, and prednisone and collection of peripheral-blood stem cells. On day 60, HDT was administered with 1,3-bis(2-chloroethyl)-1-nitrosourea, etoposide, cytarabine, and melphalan followed by ASCT. Results: Eligible patients (n = 370) with aggressive lymphoma were analyzed. For ACVBP (181 patients) and HDT (189 patients), respective complete remission rates were 64% and 63%. With a median follow-up of 60 months, 5-year overall survival and event-free survival for ACVBP and HDT were 60% +/- 8% and 46% +/- 8% (P = .007) and 52 +/- 8% and 39 8% (P = .01), respectively. Survival was independently affected by age greater than 40 years (P = .0003), T-cell phenotype (P = .009), bone marrow involvement (P = .003), and HDT treatment group (P = .04). Conclusion: Early HDT with ASCT in high-risk patients was inferior to the ACVBP chemotherapy regimen. These results indicate that the received dose-intensity before HDT was too low when compared with ACVBP and HDT and was given too early. (C) 2002 by American Society of Clinical Oncology. [less ▲] Detailed reference viewed: 9 (1 ULg) Shortened irradiation scheme, continuous infusion of 5-fluorouracil and fractionation of mitomycin C in locally advanced anal carcinomas. Results of a phase II study of the European Organization for Research and Treatment of Cancer. Radiotherapy and Gastrointestinal Cooperative Groups; ; et al in European Journal of Cancer (2003), 39 Abstract The European Organization for Research and Treatment of Cancer (EORTC) 22861 randomised trial established that combined radiochemotherapy is the standard treatment for locally advanced anal ... [more ▼] Abstract The European Organization for Research and Treatment of Cancer (EORTC) 22861 randomised trial established that combined radiochemotherapy is the standard treatment for locally advanced anal cancer. This EORTC phase II study (#22953) tests the feasibility of reducing the gap between sequences to 2 weeks, to deliver Mitomycin C (MMC) in each radiotherapy sequence and 5-FU continuously during the treatment. The first sequence consisted of 36 Gy over 4 weeks. 5-FU 200 mg/m2/days 1–26, MMC 10 mg/m2/day 1 gap 16 days. Then a second sequence of 23.4 Gy over 17 days, 5-FU 200 mg/m2/days 1–17 and, MMC 10 mg/m2/day 1 was given. 43 patients with a World Health Organization (WHO) status of 0 (n=27) or 1 (n=16) and with T2-T4, N0-3 tumours were included. Compliance with the planned treatment, doses and duration was 93%. The complete response rate was 90.7%. Grade 3 toxicities of 28, 12 and 2% were observed for skin, diarrhoea and haematological toxicities, respectively. The 3-year estimated rates for trials 22861 and 22953 are: 68 and 88% for local control; 72 and 81% for colostomy-free interval, 62 and 84% for severe late toxicity-free interval, and 70 and 81% for survival, respectively. The 22953 scheme is feasible and the results are promising. This is now considered as the new standard scheme by the EORTC. [less ▲] Detailed reference viewed: 12 (3 ULg) Shortsea shipping from hinterland ports by sea-river going vessels: study of the influence of a free cabotage policy.Marchal, Jean ![]() Conference (1994, June) Detailed reference viewed: 49 (1 ULg) Shoshonitic liquid line of descent from diorite to granite: the Late Precambrian post-collisional Tismana pluton (South Carpathians, Romania)Duchesne, Jean-Clair ; ; Liégeois, Jean-Paul et alin Lithos (1998), 45 The post-collision late-kinematic Tismana pluton belongs to the shoshonitic series. It is part of a Late Precambrian basement within the Alpine Danubian nappes of the South Carpathians (Romania). This ... [more ▼] The post-collision late-kinematic Tismana pluton belongs to the shoshonitic series. It is part of a Late Precambrian basement within the Alpine Danubian nappes of the South Carpathians (Romania). This pluton displays an exceptionally complete range of compositions from ultramafic to felsic rocks (granites). Widespread mingling/mixing relationships at all scales give rise to a variety of facies. A liquid line of descent from the diorites to the granites is reconstructed by considering the variation in major and trace elements (REE, Sr, Rb, Ba, Nb, Zr, Hf, Zn, V, Co, Cr, U, Th, Ga, Pb) from 33 selected samples as well as mineral/melt equilibrium relationships. The first step of fractional crystallization is the separation from a monzodioritic parent magma of a peridotitic cumulate similar to the ultramafic rock found in the massif. A possible contamination by lower crustal mafic component takes place at this stage. The second step marks the appearance of apatite and Fe-Ti oxide minerals as liquidus phases, and the third step, saturation of zircon. Mixing by hybridisation of magmas produced at different stages of the evolution along the liquid line of descent is also operating (endo-hybridisation). As depicted by Nd and Sr isotopes, fractional crystallization was combined to an important early contamination by a mafic lower crust in a deep-seated magma chamber and to a later and mild contamination by a felsic medium crust in an intermediate chamber. The mingling essentially occurred during the final emplacement in the high-level magma chamber. The monzodioritic parent magma, identified by major and trace element modelling, is shown by Sr and Nd isotopes to have its source in the lithospheric mantle or in a juvenile mafic lower crust derived from it. The necessarily recent enrichment in K2O and associated elements of the lithospheric mantle is likely to be related to the preceding Pan-African subduction period. The partial melting of this newly formed deep source has to be linked to a major change in the thermal state of the plate. [less ▲] Detailed reference viewed: 64 (6 ULg) |
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