Bases physiologiques et champs d’application des progestagènes en reproduction bovine

Conference (2008, May)

Bases physiopathologiques de la nutrition de l'enfant

Learning material (2012)

Basic Abstractions for an Autonomic Network Architecture

in First IEEE Workshop on Autonomic and Opportunistic Communications (2007, June)

The ANA (Autonomic Network Architecture) project aims at providing a framework to flexibly host, interconnect, and federate multiple heterogeneous networks in an autonomic way, i.e. without requiring ... [more ▼]

The ANA (Autonomic Network Architecture) project aims at providing a framework to flexibly host, interconnect, and federate multiple heterogeneous networks in an autonomic way, i.e. without requiring active human intervention. The guiding design principle is to strive for a maximum degree of flexibility at all levels of the architecture in order to inherently support heterogeneity and evolution. This paper describes the core abstractions and concepts of ANA (as defined during the first year of the project) and introduces their basic operation and interaction. While not autonomic themselves, the core architectural principles of ANA will enable autonomicity by not imposing a "one-size-fits-all" approach where protocols and paradigms are fixed by the architecture. We indeed argue that only the capacity of the network to be polyfunctional and fully adaptable will justify the label ' autonomic'. A prototype ofANA is currently being developed and will be released in 2008: the goal is to demonstrate the feasibility of autonomic networking within the 4 years of the project. [less ▲]

A Basic Comparison of Heap-Sort and Quick-Sort Algorithms

E-print/Working paper (2009)

We summarize here the biggest differences between Heap-sort and Quick-sort algorithms, two useful algorithms for array sorting.

Basic concepts of sustainable construction and review of available methodologies and tools

Conference (2011, March)

Basic Emotion Recognition and Psychopathology in Schizophrenia

in Journal of Nervous & Mental Disease (2010), 198(1), 79-81

Basic issues in the finite element simulation of extended endplate connections

in Computers & Structures (1998), 69

Basic nail surgery

in Dermatologic Clinics (2006), 24(3), 313-322

Patients often fear nail surgery because of the pain associated with anesthesia and postoperative care. Potential dystrophic sequelae are of concern to the practitioner. A thorough knowledge of the ... [more ▼]

Patients often fear nail surgery because of the pain associated with anesthesia and postoperative care. Potential dystrophic sequelae are of concern to the practitioner. A thorough knowledge of the techniques of anesthesia, nail anatomy, and surgical procedures is a prerequisite for successful nail surgery with almost no pain and minimal scarring. It also is mandatory to involve a dermatopathologist who is familiar with the histologic idiosyncrasies of the nail unit. [less ▲]

Basic perinatal care

Learning material (2011)

The Basic Property of Lys385 Is Important for Potentiation of the Human alpha1 Glycine Receptor by Ethanol.

in Journal of Pharmacology and Experimental Therapeutics (2012), 340(2), 339-49

Ethanol alters the function of several members of the Cys-loop ligand-gated ion channel superfamily. Recent studies have shown that the sensitivity of the alpha1 glycine receptor (GlyR) to ethanol can be ... [more ▼]

Ethanol alters the function of several members of the Cys-loop ligand-gated ion channel superfamily. Recent studies have shown that the sensitivity of the alpha1 glycine receptor (GlyR) to ethanol can be affected by the state of G protein activation mediated by the interaction of Gbetagamma with intracellular amino acids in the GlyR. Here, we evaluated the physicochemical property of Lys385 that contributes to ethanol modulation by using mutagenesis, patch-clamp, and biochemical techniques. A conserved substitution (K385R) did not affect either the apparent glycine EC(50) (40 +/- 1 versus 41 +/- 0.5 muM) or the ethanol-induced potentiation (53 +/- 5 versus 46 +/- 5%) of the human alpha1 GlyR. On the other hand, replacement of this residue with glutamic acid (K385E), an acidic amino acid, reduced the potentiation of the GlyR to 10 +/- 1%. Furthermore, mutations with a hydrophobic leucine (K385L), a hydrogen bond donor glutamine (K385Q), or a neutral residue (K385A) also reduced ethanol modulation. Finally, substitution by a large and hydrophobic residue (K385F) and deletion of 385 (Lys385_) reduced ethanol modulation to 10 +/- 4 and 17 +/- 0.4%, respectively. Experiments using dynamic cysteine substitution with a methanethiosulfonate reagent and homology modeling indicate that the basic property and the position of Lys385, probably because of its interaction with Gbetagamma, is critical for ethanol potentiation of the receptor. [less ▲]