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See detaillambda Boo stars among the gamma Dor-type pulsators: the cases of HD 218427 and HD 239276
Rodríguez, E.; Suárez, J. C.; Moya, A. et al

in Communications in Asteroseismology (2007), 150

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See detailLambdoid synostosis - pachycephaly: diagnosis and treatment
Misson, Jean-Paul ULg; Born, Jacques; Collignon, L. et al

in Developmental Medicine and Child Neurology. Supplement (1995), 37(3), 87

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See detailLambeau hétéroplapébral dans la reconstruction de la paupière inférieure : expérience de 21 ans
BATCHVAROVA, Z; XHAUFLAIRE, Gaël ULg; KRASTINOVA, Darina

Conference (2009, April 23)

Introduction : L’importance physiologique de la paupière inférieure est souvent sous-estimée. Si la protection du globe oculaire est assurée essentiellement par la paupière supérieure, c’est la paupière ... [more ▼]

Introduction : L’importance physiologique de la paupière inférieure est souvent sous-estimée. Si la protection du globe oculaire est assurée essentiellement par la paupière supérieure, c’est la paupière inférieure qui assure le drainage lacrymal, complète l’occlusion palpébrale et joue un rôle important dans le regard et l’expression du visage. Choisir la technique simple et fiable pour reconstruire une perte de substance de la paupière inférieure et rétablir sa fonction et son esthétique est une épreuve pour le chirurgien. Objectifs et Méthodes : Nous rapportons notre expérience de 21 ans dans la reconstruction de la paupière inférieure par un lambeau hétéro-palpébral de la paupière supérieure. Discussion : Nous décrivons notre technique chirurgicale, les différents types de lambeaux, leurs indications et les gestes associés qui nous ont permis d’obtenir de très bon résultats fonctionnels et esthétiques chez 173 patients, porteurs de pathologies palpébrales variées : malformations congénitales, paralysie faciale, anophtalmie, brûlures, tumeurs, séquelles post traumatiques, ectropion involutif et complications post blépharoplastie esthétique. Conclusion : Dans la reconstruction de la paupière inférieure le lambeau hétéro- palpébral apporte des tissus identiques, un support dynamique, il soutient le globe oculaire et permet la réalisation des gestes associés. [less ▲]

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See detailLambert Lombard, pictor et inventor
Allart, Dominique ULg

Conference given outside the academic context (2010)

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See detail“Lambertus pictor” in the Saint Denis church accounts of 1533: new developments
Joly, Emmanuel ULg

Conference (2015, October 22)

The State archives in Liège preserve some of the 16th century “fabrique“ accounts of the Saint Denis collegiate church of Liège. Among them, accounts of the year 1533 drew the attention of Jean Yernaux in ... [more ▼]

The State archives in Liège preserve some of the 16th century “fabrique“ accounts of the Saint Denis collegiate church of Liège. Among them, accounts of the year 1533 drew the attention of Jean Yernaux in his 1958 study about Lambert Lombard. Indeed he found what he thought to be the proof of the Liège Renaissance Master’s intervention in the painting of the Saint Denis Altarpiece panels, before giving up the attribution in 1970. Since then, these two mentions have been used to illustrate either the involvement of Lombard or of another painter named “Lambert” in the painting of the panels. But looking closer at the original document, it is obvious that Yernaux committed huge mistakes in the transcript of these mentions. Not only was he wrong about the sums paid to the artist but also about the work mentioned in this account. In order to understand this document fully and correctly, it is therefore essential to propose a transcription from which new interpretations can be generated. This new understanding can then lead to further contextualization of the mentions. These accounts need to be looked at in close relationship with the rest of the document. This would shed new light on the writer’s habits, especially when it comes to designate individuals. The amount of money given to the painter Lambert also needs to be assessed. Comparisons to other payments of the same period conserved in the archives of the Saint Denis church and of other churches in or around Liège are going to be unveiled and investigated. This will give interesting clues to understand better the extent of the work done by the artist as well as his social status. [less ▲]

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See detailLambinonia, a new genus for Melanconium strigulae, a lichenicolous hyphomycete on foliicolous species of Strigula
Sérusiaux, Emmanuel ULg; Diederich, P.

in Lichenologist (2005), 37(Part 6), 499-506

The new genus Lambinonia Serus.

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See detailLambotte, Lucien
Pirenne, Christophe ULg

in Nouvelle Biographie Nationale (2003)

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See detailLamellibranche dans le Revinien
Malaise, Constantin ULg

in Annales de la Société Géologique de Belgique (1910), 37

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See detailLaminar difference in GABA uptake and GAT-1 expression in rat CA1
Engel, Dominique ULg; Schmitz, D; Gloveli, T et al

in Journal of Physiology (1998), 512(Pt3), 643-649

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See detailLaminar flow in radial flow cell with small aspect ratios: Numerical and experimental study
Detry, Jean; Deroanne, Claude ULg; Sindic, Marianne ULg et al

in Chemical Engineering Science (2009), 64(1), 31-42

Studies on the effect of wall shear stress on soil and biofilm attachment and removal from a surface are one of the many applications of radial axisymmetrical flow. The particular nature of this flow ... [more ▼]

Studies on the effect of wall shear stress on soil and biofilm attachment and removal from a surface are one of the many applications of radial axisymmetrical flow. The particular nature of this flow allows taking advantage of a wide range of wall shear Stress applied at the analyzed surface in a single experiment. This type of experiments provides a critical radius up to which soil removal occurs. Good models are, however, still needed to convert the experimental data into critical wall shear stress. Analytical models are already available for creeping flow but Computational Fluid Dynamics must be applied for experiments performed at higher Reynolds numbers. The present study is a numerical analysis of the radial axisymmetrical flow for aspect ratios of 0.125, 0.25, 0.5 and 1 with inlet pipe Reynolds numbers varying from 0 to 2000, aiming at computing the wall shear stress distribution at any distance from the center. The simulations provided a thorough description of the complex flow pattern encountered close to the inlet section, which were validated for the laminar regime by dye injection. A total of up to four recirculation zones were identified in both numerical and experimental investigations. The experimental positions of these recirculation zones corresponded well to the numerical predictions. Based on this work, a map of the flow for the different aspect ratios was developed, which can be particularly interesting for the design of experimental devices involving axisymmetrical flow. (c) 2008 Elsevier Ltd. All rights reserved. [less ▲]

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See detailLaminarin in the dietary fibre concept
Deville, Christelle ULg; Damas, Jacques ULg; Forget, Pierre et al

in Journal of the Science of Food and Agriculture (2004), 84(9), 1030-1038

Dietary fibres consist of edible plant polysaccharides that are resistant to digestion and absorption in the human small intestine but undergo complete or partial fermentation in the colon. Seaweeds ... [more ▼]

Dietary fibres consist of edible plant polysaccharides that are resistant to digestion and absorption in the human small intestine but undergo complete or partial fermentation in the colon. Seaweeds, notably Laminaria spp, are particularly rich in polysaccharides resistant to hydrolysis in the upper gastrointestinal tract and are, in consequence, considered as dietary fibres. Most of the carbohydrates from Laminaria spp are thought to be indigestible by humans. The main storage polysaccharide of these algae is laminarin, a beta-polymer of glucose. The aims of this work were, on the one hand, to compare various methods of extraction of laminarin by partial characterisation of the product obtained and, on the other hand, to study the fate of this polysaccharide and its effects in the gastrointestinal tract in order to determine its potential as a dietary fibre in human nutrition. Among four methods tested to extract laminarin, the best appeared to be a hot HCl-based method. Human digestive enzymes did not hydrolyse laminarin, so this polysaccharide can be considered as a dietary fibre. After ingestion by rats, this polysaccharide was not found in faeces of these animals. It did not increase the intestinal transit and stool output in vivo, but it increased the contractile response of the stomach to acetylcholine in vitro. (C) 2004 Society of Chemical Industry. [less ▲]

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See detailLaminin and 67 Kd Laminin Binding Protein in Mouse B16 Melanoma Cells and 3t3 Fibroblast Spheroids
Siwek, B. L.; Munaut, Carine ULg; Bonjean, K. A. et al

in Anticancer Research (1992), 12(6B, Nov-Dec), 2011-6

Multicellular spheroids which promote cell-cell and cell-matrix interactions were prepared in culture with mouse B16 melanoma cells (pigmented or non pigmented) alone or mixed with mouse 3T3 fibroblasts ... [more ▼]

Multicellular spheroids which promote cell-cell and cell-matrix interactions were prepared in culture with mouse B16 melanoma cells (pigmented or non pigmented) alone or mixed with mouse 3T3 fibroblasts. Their volume and proliferation or necrosis rate were evaluated. As measured by dot blot immunoassay, laminin was mainly produced by fibroblasts rather than by melanoma cells. High levels of laminin B1 chain mRNA were detected only in spheroids composed of 3T3 fibroblasts. The levels of 67 kD laminin binding protein mRNA were high in all cell populations studied here. [less ▲]

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See detailLaminin and fibronectin increase the steady state level of the 67 kD high affinity metastasis-associated laminin receptor mRNA in human cancer cells.
Castronovo, Vincenzo ULg; Sobel, M. E.

in Biochemical and Biophysical Research Communications (1990), 168(3), 1110-7

Among the various known laminin binding proteins, the 67 kD high affinity laminin receptor (LR) is intimately involved during tumor invasion and metastasis. In this study, we report that laminin and ... [more ▼]

Among the various known laminin binding proteins, the 67 kD high affinity laminin receptor (LR) is intimately involved during tumor invasion and metastasis. In this study, we report that laminin and fibronectin, two attachment glycoproteins, significantly increased the total cellular level of 67 kD LR mRNA in two human cancer cell lines, T47D breast carcinoma cells and A2058 melanoma cells. Neither GRGDS nor YIGSR synthetic peptides induced such a stimulatory effect. Since the steady state level of LR mRNA has been shown to control the number of receptors expressed at the cell surface, these results suggest that contact of the cancer cells with laminin and fibronectin in the host matrix may be an important regulatory mechanism by which cancer cells maintain a high number of LR at their cell surface as they progress through the several steps of tumoral invasion and metastasis. [less ▲]

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See detailLaminin and Type Iii Procollagen Peptide in Human Preovulatory Follicular Fluid
Christiane, Y.; Demoulin, A.; Gillain, D. et al

in Fertility and Sterility (1988), 50(1), 48-51

The levels of laminin P1 fragment, a marker of basement membrane, and of the aminoterminal sequence of type III procollagen, a marker of interstitial connective tissue, were measured in human preovulatory ... [more ▼]

The levels of laminin P1 fragment, a marker of basement membrane, and of the aminoterminal sequence of type III procollagen, a marker of interstitial connective tissue, were measured in human preovulatory follicular fluids. The concentrations of these peptides correlated with progesterone levels but not with those of estradiol or testosterone. Immunocytochemical studies confirmed the remodeling of the perifollicular basement membrane and interstitial matrix during oocyte maturation. The studies suggest that monitoring of the ovarian connective tissue macromolecules could be useful for estimating follicular maturation. [less ▲]

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See detailLaminin binding and internalization by human and murine mammary gland cell lines in vitro.
Coopman, P. J.; Nuydens, R.; Leunissen, J. et al

in European Journal of Cell Biology (1991), 56(2), 251-9

We have studied the binding and internalization of Engelbreth-Holm-Swarm mouse sarcoma laminin labeled with colloidal gold (LN-G40) by human and murine mammary gland cell lines. Interactions between the ... [more ▼]

We have studied the binding and internalization of Engelbreth-Holm-Swarm mouse sarcoma laminin labeled with colloidal gold (LN-G40) by human and murine mammary gland cell lines. Interactions between the LN-G40 probe and the cells spread on a glass coverslip were monitored with video-enhanced contrast microscopy (Nanovid). Transmission electron microscopy allowed the quantitation of the LN-G40 probe at various cellular locations. During the first 15 min, a homogeneous binding of LN-G40 probe to the cell surface was observed with all cell lines. This binding did not occur with gold particles that were not conjugated to laminin. Then, the LN-G40 probe began to cluster on the cell surface and was, during the following 20 h, internalized by pits that were not coated. In the cells, the LN-G40 probe sometimes showed saltatory movements along linear tracks. The LN-G40 probe was intracellularly found in vesicles, multivesicular bodies, cisternal structures, and lysosomes, suggesting the degradation of the internalized laminin. However, not all cell surface-bound LN-G40 probe was internalized after 20 h. Differences between the cell lines were quantitative, but no clear correlation could be made between migration of cells on laminin and internalization of laminin. [less ▲]

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See detailLaminin promotes cerebellar granule cells migration in vitro and is synthesized by cultured astrocytes
SELAK, Ivan ULg; Foidart, Jean-Michel ULg; Moonen, Gustave ULg

in Developmental Neuroscience (1985), 7(5-6), 278-285

Newborn rat cerebellum microexplants have been used as a model to study neuronal migration. Laminin in a substrate-bound form modifies extensively the migratory behavior of the neurones, an effect which ... [more ▼]

Newborn rat cerebellum microexplants have been used as a model to study neuronal migration. Laminin in a substrate-bound form modifies extensively the migratory behavior of the neurones, an effect which is blocked if antilaminin antibodies are present during the assay. 35S methionine incorporation followed by SDS-PAGE electrophoresis, fluorography and immunoprecipitation with antilaminin antibodies allowed to demonstrate that laminin is synthesized and secreted by cultured newborn rat cerebellum as well as by cultured newborn rat cerebral cortex astrocytes. [less ▲]

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See detailLaminin receptor complementary DNA-deduced synthetic peptide inhibits cancer cell attachment to endothelium.
Castronovo, Vincenzo ULg; Taraboletti, G.; Sobel, M. E.

in Cancer Research (1991), 51(20), 5672-8

Stable attachment of cancer cells to the endothelium is a key step in the formation of metastasis. In this study, we have investigated the possibility that interaction between laminin and its Mr 67,000 ... [more ▼]

Stable attachment of cancer cells to the endothelium is a key step in the formation of metastasis. In this study, we have investigated the possibility that interaction between laminin and its Mr 67,000 high-affinity receptor (67 LR) could play a major role in this process. Scatchard analysis of laminin-binding studies showed that bovine aortic endothelial cells exhibit 46,000 high-affinity receptors that mediate, at least in part, the attachment of highly invasive melanoma cells. This endothelial cell-melanoma cell interaction was significantly inhibited by soluble laminin and by anti-laminin antibodies. Peptide G, an eicosapeptide derived from the complementary DNA sequence of the 67 LR precursor (IPCNNKGAHSVGLMWWMLAR) that specifically binds to laminin and presumably contains the active ligand-binding site of the receptor, specifically prevented attachment of the melanoma cells to both the bovine aortic endothelial cell monolayer and human umbilical vein endothelium. Thus, peptide G may selectively interfere with the metastatic cascade by inhibiting tumor cell attachment to endothelium via the laminin-67 LR pathway and is a potential new antimetastatic agent. [less ▲]

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See detailLaminin Receptors and Laminin-Binding Proteins During Tumor Invasion and Metastasis
Castronovo, Vincenzo ULg

in Invasion & Metastasis (1993), 13(1), 1-30

Interactions between cancer cells and laminin, a major component of basement membranes, play a critical role at several steps of the complex process of tumor invasion and metastasis. These interactions ... [more ▼]

Interactions between cancer cells and laminin, a major component of basement membranes, play a critical role at several steps of the complex process of tumor invasion and metastasis. These interactions are mediated through a large variety of cell surface proteins designated as laminin receptors and/or laminin-binding proteins. The growing number of identified laminin binding proteins and domains of this glycoprotein that are biologically active illustrate the complexity of cellular interactions with laminin. The 67-kD laminin receptor (67 LR) was the first protein identified in 1983 as a high-affinity laminin receptor, and its expression is dramatically increased in a large variety of cancer cells. The 67 LR is the subject of several controversies and confusion generated mainly by two events. First, the identification of several new laminin-binding proteins has raised the difficult task of attributing specific functions to specific receptors in contrast to initial beliefs that all cellular laminin-driven biological activities were mediated through the 67 LR. The second source of controversy is the large molecular-weight discrepancy between the 37-kD polypeptide encoded by the 67 LR cDNA clone and the mature 67 LR. In this manuscript, a critical and extensive review of the data accumulated on the 67 LR is presented regarding both its molecular structure and its role during tumor invasion and metastasis. A hypothetical model of the 67 LR is also proposed. Since the first identification of the 67 LR, at least 14 other cell surface molecules have been reported to be potential laminin receptors or laminin-binding proteins. These include members of the beta-galactoside-binding lectin family, seven members of the integrin family, the galactosyltransferase and some not yet fully characterized cell surface molecules. These laminin receptors and laminin-binding proteins are also described and their functions are also discussed with a particular emphasis on their participation in the constitution of the invasive phenotype. [less ▲]

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