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See detailA new topical treatment for resistant herpes simplex infections.
Snoeck, R.; Andrei, G.; De Clercq, E. et al

in New England Journal of Medicine [=NEJM] (1993), 329(13), 968-9

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See detailA new tracer technique for monitoring groundwater fluxes : the finite volume point dilution method
Brouyère, Serge ULg; Batlle-Aguilar, Jordi; Goderniaux, Pascal ULg et al

Conference (2008, June 06)

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See detailA New Tracer Technique for Monitoring Groundwater Fluxes: The Finite Volume Point Dilution Method
Brouyère, Serge ULg; Batlle-Aguilar, Jordi; Goderniaux, Pascal ULg et al

in Journal of Contaminant Hydrology (2008), 95(3-4), 121-40

Quantification of pollutant mass fluxes is essential for assessing the impact of contaminated sites on their surrounding environment, particularly on adjacent surface water bodies. In this context, it is ... [more ▼]

Quantification of pollutant mass fluxes is essential for assessing the impact of contaminated sites on their surrounding environment, particularly on adjacent surface water bodies. In this context, it is essential to quantify but also to be able to monitor the variations with time of Darcy fluxes in relation with changes in hydrogeological conditions and groundwater - surface water interactions. A new tracer technique is proposed that generalizes the single-well point dilution method to the case of finite volumes of tracer fluid and water flush. It is called the Finite Volume Point Dilution Method (FVPDM). It is based on an analytical solution derived from a mathematical model proposed recently to accurately model tracer injection into a well. Using a non-dimensional formulation of the analytical solution, a sensitivity analysis is performed on the concentration evolution in the injection well, according to tracer injection conditions and well-aquifer interactions. Based on this analysis, optimised field techniques and interpretation methods are proposed. The new tracer technique is easier to implement in the field than the classical point dilution method while it further allows monitoring temporal changes of the magnitude of estimated Darcy fluxes, which is not the case for the former technique. The new technique was applied to two experimental sites with contrasting objectives, geological and hydrogeological conditions, and field equipment facilities. In both cases, field tracer concentrations monitored in the injection wells were used to fit the calculated modelled concentrations by adjusting the apparent Darcy flux crossing the well screens. Modelling results are very satisfactory and indicate that the methodology is efficient and accurate, with a wide range of potential applications in different environments and experimental conditions, including the monitoring with time of changes in Darcy fluxes. [less ▲]

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See detailA new training simulator for improved voltage control of the Hydro-Québec system
Van Cutsem, Thierry ULg; Hassé, Gaëtan; Moors, Cédric et al

(2004, October)

This paper reports on the development of a training simulator focusing on voltage control and stability. It has been derived from a quasi steady-state simulation software already used and validated in ... [more ▼]

This paper reports on the development of a training simulator focusing on voltage control and stability. It has been derived from a quasi steady-state simulation software already used and validated in planning and operational planning studies. The computational engine has been provided with a user interface built on the client-server architecture, allowing the simulator to run on a network of PCs in a very flexible way. New displays can be set up easily and quickly. This tool is presently used by Hydro-Québec to improve the operator’s ability to control transmission voltages. Other features, uses and benefits are reported. [less ▲]

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See detailNew Transfer Functions for Correcting Turbulent Water Vapour Fluxes
De Ligne, Anne ULg; Heinesch, Bernard ULg; Aubinet, Marc ULg

in Boundary-Layer Meteorology (2010), 137(2), 205-221

We address the problem of the high-frequency correction of water vapour fluxes measured by eddy covariance with a closed-path infrared gas analyser (IRGA). Different transfer functions are compared and ... [more ▼]

We address the problem of the high-frequency correction of water vapour fluxes measured by eddy covariance with a closed-path infrared gas analyser (IRGA). Different transfer functions are compared and evaluated at a forested (Vielsalm, Belgium) and an agricultural (Lonz,e, Belgium) site. Classical functions, usually applied to correct CO2 fluxes (Gaussian, Lorentzian), are found to be unsuited to water vapour cospectral corrections, being characterised by too sharp a decrease at high frequency. Two other functions characterised by a lower decreasing slope are found to better fit experimental transfer functions. They were calibrated and validated on experimental transfer functions and their dependency on air humidity is parameterised. On this basis, new correction coefficients are estimated. The coefficients are found to be larger than those based on the classical functions, even when the dependency of the latter on air humidity is taken into account. The difference amounts to 10 at the forested site and to 5 larger at the crop site. The study highlights the necessity of characterising the water transfer function shape and taking it into account in the correction factor at each site equipped with a closed path IRGA. [less ▲]

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See detailA new treatment for the reduction of vertebral and non-vertebral fractures in post-menopausal women with osteoporosis
Reginster, Jean-Yves ULg; Brixen, Kim; Bianchi, Gerolamo et al

in Arthritis and Rheumatism (2004, September), 50(number 9 (suppl.)), 291

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See detailNew trends in anti-malarial agents
Frederich, Michel ULg; Dogné, Jean-Michel ULg; Angenot, Luc ULg et al

in Current Medicinal Chemistry (2002), 9(15), 1435-1456

Malaria is the major parasitic infection in many tropical and subtropical regions, leading to more than one million deaths (principally young African children) out of 400 million cases each year (WHO ... [more ▼]

Malaria is the major parasitic infection in many tropical and subtropical regions, leading to more than one million deaths (principally young African children) out of 400 million cases each year (WHO world health report 2000). More than half of the world's population live in areas where they remain at risk of malaria infection. During last years, the situation has worsened in many ways, mainly due to malarial parasites becoming increasingly resistant to several antimalarial drugs. Furthermore, the control of malaria is becoming more complicated by the parallel spread of resistance of the mosquito vector to currently available insecticides. Discovering new drugs in this field is therefore a health priority. Several new molecules are under investigation. This review describes the classical treatments of malaria and the latest discoveries in antimalarial agents, especially artemisinin and its recent derivatives as well as the novel peroxidic compounds. [less ▲]

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See detailNew trends in clinical toxicology
Charlier, Corinne ULg; Plomteux, Guy ULg

Conference (1996, October)

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See detailNew Trends in Computing Anticipatory Systems : Emergence of Artificial Conscious Intelligence with Machine Learning Natural Language
Dubois, Daniel ULg

in Dubois, Daniel (Ed.) COMPUTING ANTICIPATORY SYSTEMS (2008)

This paper deals with the challenge to create an Artificial Intelligence System with an Artificial Consciousness. For that, an introduction to computing anticipatory systems is presented, with the ... [more ▼]

This paper deals with the challenge to create an Artificial Intelligence System with an Artificial Consciousness. For that, an introduction to computing anticipatory systems is presented, with the definitions of strong and weak anticipation. The quasi-anticipatory systems of Robert Rosen are linked to open-loop controllers. Then, some properties of the natural brain are presented in relation to the triune brain theory of Paul D. MacLean, and the mind time of Benjamin Libet, with his veto of the free will. The theory of the hyperincursive discrete anticipatory systems is recalled in view to introduce the concept of hyperincursive free will, which gives a similar veto mechanism: free will as unpredictable hyperincursive anticipation The concepts of endo-anticipation and exo-anticipation are then defined. Finally, some ideas about artificial conscious intelligence with natural language are presented, in relation to the Turing Machine, Formal Language, Intelligent Agents and Mutli-Agent System. [less ▲]

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See detailNew trends in dual 5-LOX/COX inhibition
De Leval, X.; Julémont, F.; Delarge, J. et al

in Current Medicinal Chemistry (2002), 9

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See detailNew trends in flood risk analysis: working with 2D flow models, laser DEM and a GIS environment
Archambeau, Pierre ULg; Dewals, Benjamin ULg; Erpicum, Sébastien ULg et al

in Greco, M.; Carravetta, A.; Della Morte, R. (Eds.) Proceedings of the 2nd International Conference on Fluvial Hydraulics: River Flow 2004 (2004)

This paper outlines the integration of new and accurate laser DEM into the determination of floodplains. Global and robust GIS environment is absolutely necessary to manage this very large amounts of ... [more ▼]

This paper outlines the integration of new and accurate laser DEM into the determination of floodplains. Global and robust GIS environment is absolutely necessary to manage this very large amounts of topographic data. The development and interaction of 2D flow models, simplified or not, ensures to offer more accurate and flexible physically based tools to the decision-makers. [less ▲]

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See detailNew Trends in Hot Strip Mill Roughing Mills: Characterization of High Chromium Steel and Semi-HSS Grades
Lecomte-Beckers, Jacqueline ULg; Sinnaeve, Mario; Tchuindjang, Jérôme Tchoufack ULg

in Proceedings of the Iron & Steel Technology Conference (AISTech 2011) (2011)

Two alloys grades for work rolls used in the roughing stand of Hot Strip Mill (HSM) are compared. The first grade known as High Chromium Steel (HCS) is presently the most widely used alloy for such an ... [more ▼]

Two alloys grades for work rolls used in the roughing stand of Hot Strip Mill (HSM) are compared. The first grade known as High Chromium Steel (HCS) is presently the most widely used alloy for such an application, while the second one known as semi-High-speed Steel (semi-HSS) is the new grade developed to improve the overall performance of the work roll in the roughing stands of the HSM. In the present paper, the new semi-HSS grade is studied starting from three chemical compositions closed one to another, the variation in the alloying elements is intended to assess, on one hand the effect of a small increase of the carbon content, and on the other hand the influence of the addition of a strong MC carbide forming element. The comparison of HCS and semi-HSS grades involves many fields. Regarding the metallurgical aspect, such a comparison led to the enhancement of the solidification range, the crystallization behavior and the microstructure in the as-cast condition for both grades. Furthermore, corrosion behavior and performances of the work rolls in service are compared. Various techniques are used in order to characterize both grades, such as Differential Thermal Analysis (to determine phase transformations temperatures, the crystallization behavior and the interval of solidification), hardness measurements, optical microscopy, scanning electron microscopy associated with energy dispersive X-ray spectroscopy (to determine the nature and the composition of phases, especially matrix and carbides). Finally micro-macro relations between the nature of the microstructure and the properties of HCS and semi-HSS rolls grades in service conditions could be established. [less ▲]

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See detailNew trends in selenium-labeled compounds synthesis.
Christiaens, L.; Guillaume, M.; Luxen, André ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1982), 19

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See detailNew trends in the design of drugs against Alzheimer's disease
Francotte, Pierre ULg; De Tullio, Pascal ULg; Fraikin, Pierre ULg et al

in Frontiers in Medicinal Chemistry (2006), 3

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See detailNew trends in the design of drugs against Alzheimer's disease
Francotte, Pierre ULg; Graindorge, Emmanuel; Boverie, Stéphane et al

in Current Medicinal Chemistry (2004), 11(13), 1757-1778

First described by Alois Alzheimer in 1907, Alzheimer's disease (AD) is the most common dementia type, affecting approximately 20 million people worldwide. As the population is getting older, AD is a ... [more ▼]

First described by Alois Alzheimer in 1907, Alzheimer's disease (AD) is the most common dementia type, affecting approximately 20 million people worldwide. As the population is getting older, AD is a growing health problem. AD is currently treated by symptomatic drugs, the acetylcholinesterase inhibitors. based on the cholinergic hypothesis (1976). During the past decade, advances in neurobiology have conducted to the identification of new targets. Although some of these innovative approaches tend to delay onset of AD, others are still symptomatic. In this review, we present an overview of the several strategies and new classes of compounds against AD. [less ▲]

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See detailNew trends in the development of positive allosteric modulators of AMPA receptors
Graindorge, E.; Francotte, Pierre ULg; Boverie, S. et al

in Current Medicinal Chemistry - Central Nervous System Agents (2004), 4

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See detailNew trends in the diagnosis and treatment of recurrent inflammation in competition horses
Lekeux, Pierre ULg; Thomas, A.; Art, Tatiana ULg et al

in Pferdeheilkunde (2006)

Detailed reference viewed: 22 (6 ULg)