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Peer Reviewed
See detailA New Quicklook Optical Processor with Digital Input/Output
Litovchenko, Konstantin Ts.; Lemaire, Philippe; Barbier, Christian ULg

in Proceedings IGARSS'96 Symposium (1996)

Detailed reference viewed: 8 (1 ULg)
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See detailNew quinazolinones structurally related to diazoxide and pinacidil as potential KATP channel openers
Somers, F.; Ouedraogo, R.; De Tullio, Pascal ULg et al

Conference (1998, February 14)

Detailed reference viewed: 6 (0 ULg)
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See detailNew quinazolinones structurally related to diazoxide and pinacidil as potential KATP channel openers
Somers, F.; Ouedraogo, R.; De Tullio, Pascal ULg et al

in Fundamental & Clinical Pharmacology (1998), 12

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See detailNew R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as KATP channel openers: modulation of the 4-position
Florence, Xavier ULg; Sebille, Sophie; De Tullio, Pascal ULg et al

in Bioorganic & Medicinal Chemistry (2009), 17

Detailed reference viewed: 33 (5 ULg)
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See detailNew radiocarbon dates for the Zagros Aurignacian from Yafteh cave, Iran
Otte, Marcel ULg; Shidrang, Sonia; Zwyns, Nicolas et al

in Journal of Human Evolution (2011), 61(3), 340-346

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See detailNew radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents
Oltenfreiter, R.; Staelens, L.; Lejeune, Annabelle ULg et al

in Nuclear Medicine & Biology (2004), 31(4), 459-468

Several studies have demonstrated a positive correlation between tumor progression and expression of extracellular proteinases such as matrix metalloproteinases (MMPs). MMP-2 and MMP-9 have become ... [more ▼]

Several studies have demonstrated a positive correlation between tumor progression and expression of extracellular proteinases such as matrix metalloproteinases (MMPs). MMP-2 and MMP-9 have become attractive targets for cancer research because of their increased expression in human malignant tumor tissues of various organs, providing a target for medical imaging techniques. Radioiodinated carboxylic and hydroxamic MMP inhibitors 2-(4'-[123]iodo-biphenyl-4-sulfonylainino)-3-(1H-indol-3-yl)-propionic acid (9) and 2-(4'-[I-123] iodo-biphenyl-4-sulfonylamino)-3-(1H-indol-3-yl)-propionamide (11) were synthesized by electrophilic aromatic substitution of the tributylstannyl derivatives and resulted in radiochemical yields of 60% +/- 5% (n - 3) and 70% +/- 5% (n = 6), respectively. In vitro zymography and enzyme assays showed high inhibition capacities of the inhibitors on gelatinases. In vivo biodistribution showed no long-terin accumulation in organs and the possibility to accumulate in the tumor. These results warrant further studies of radioiodinated carboxylic and hydroxamic MNIP inhibitor tracers as potential SPECT tumor imaging agents. (C) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailNew rationales for using TGFbeta inhibitors in radiotherapy.
Andarawewa, Kumari L.; Paupert, Jenny ULg; Pal, Anupama et al

in International journal of radiation biology (2007), 83(11-12), 803-11

PURPOSE: The first reports that ionizing radiation (IR) induces rapid and persistent activation of transforming growth factor beta1 (TGFbeta) were nearly two decades ago. Subsequent studies have shown ... [more ▼]

PURPOSE: The first reports that ionizing radiation (IR) induces rapid and persistent activation of transforming growth factor beta1 (TGFbeta) were nearly two decades ago. Subsequent studies have shown that TGFbeta is a major mediator of cellular and tissue responses to IR and have revealed novel facets of its complex biology. RESULTS: We and others have recently shown that inhibition of production or signaling of TGFbeta in epithelial cells modulates radiosensitivity and impedes activation of the DNA damage response program. The primary transducer of cellular response to DNA damage caused by ionizing radiation is the nuclear protein kinase ataxia telangiectasia mutated, whose activity is severely compromised when TGFbeta is inhibited. Thus, in conjunction, with its well-recognized contribution to normal tissue fibrosis, the role of TGFbeta in the genotoxic stress program provides a previously unsuspected avenue to modulate radiotherapy. CONCLUSIONS: We hypothesize that identification of the circumstances and tumors in which TGFbeta manipulation enhances tumor cell radiosensitivity, while protecting normal tissues, could significantly increase therapeutic index. [less ▲]

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See detailA new real time biomimetic membrane biosensor based on a capacitive readout ASIC for Antibiotics
Kibler, S; Zimmermann, T; Pierrat, S et al

in Proceedings of "Transducers 2013, M3P.085: Espagne - Juin 2013" (2013, June)

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See detailNew record of Encheliophis dubius (Carapidae) off Madagascar ?
Parmentier, Eric ULg; Bailly, Nicolas

in Cybium (2002), 26

When checking the identification of the Carapidae in the MNHN collection (Muséum National d’Histoire Naturelle, Paris) a specimen of Eurypleuron owasianum (Matsubara, 1953) (MNHN 1992-0914) caught off ... [more ▼]

When checking the identification of the Carapidae in the MNHN collection (Muséum National d’Histoire Naturelle, Paris) a specimen of Eurypleuron owasianum (Matsubara, 1953) (MNHN 1992-0914) caught off Madagascar (20°S, 42°30’E) was found to be incorrectly identified. The specimen is vey close to Carapus dubius (Putnam, 1874), which is known from the Eastern Pacific (Markle and Olney, 1990). [less ▲]

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See detailA new red colonial Pseudanabaena (Cyanoprokaryota, Oscillatoriales) from North American large lakes
Kling, H; Laughinghouse IV, Haywood ULg; Smarda, J et al

in Fottea (Praha) (2012), 12(2), 327-339

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See detailNew reflections on the sources, outcomes, defining features and motivations of grammaticalization
Breban, Tine; Vanderbiesen, Jeroen; Davidse, Kristin et al

in Breban, Tine; Brems, Lieselotte; Davidse, Kristin (Eds.) et al Grammaticalization and language change: new reflections (2012)

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See detailNew regional initiatives in pigeonpea improvement
Kimani, PM; Mergeai, Guy ULg; Silim, SN et al

in Proceedings Regional Workshop on Status and Potential of Pigeonpea in Eastern and Southern Africa (2001)

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See detailThe new Regulation Rome III
Pfeiff, Silvia ULg

Conference (2013)

Detailed reference viewed: 5 (0 ULg)
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See detailNew relative K+-sparing high ceiling diuretics related to torasemide
Masereel, B.; Schynts, M.; Lorhmann, E. et al

Poster (1991, September)

Detailed reference viewed: 6 (0 ULg)
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See detailNew relative K+-sparing high ceiling diuretics related to torasemide
Masereel, B.; Schynts, M.; Lohrmann, E. et al

Conference (1992)

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See detailNew relative K+-sparing high ceiling diuretics related to torasemide
Masereel, B.; Schynts, M.; Lohrmann, E. et al

in Journal de Pharmacie de Belgique (1992), 47

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See detailA new representative of the lichid genus Ohleum (Trilobita) from the Eifelian (Middle Devonian) of southern Belgium
Taghon, Peter; Bonino, Enrico; Mottequin, Bernard ULg

in Geologica Belgica (2012), 15(3), 120-125

Trilobites of the family Lichidae are relatively poorly diversified within the Eifelian mixed siliciclastic-carbonate succession of the southern margin of the Dinant Synclinorium (Belgium). Until now ... [more ▼]

Trilobites of the family Lichidae are relatively poorly diversified within the Eifelian mixed siliciclastic-carbonate succession of the southern margin of the Dinant Synclinorium (Belgium). Until now, they were only represented by species belonging to the genera Ceratarges and Eifliarges. The recent discovery of a well-preserved specimen within the Eifelian-aged Jemelle Formation in the Couvin area led us to propose the first detailed description of a representative of the genus Ohleum (Ohleum magreani sp. nov.) in the Ardennes. [less ▲]

Detailed reference viewed: 231 (13 ULg)