The left intraparietal sulcus and verbal short-term memory: Focus of attention or serial order ?
Majerus, Steve ; Poncelet, Martine ; Van der Linden, Martial et al
in Neuroimage (2006), 32(2), 880-891
One of the most consistently activated regions during verbal short-term memory (STM) tasks is the left intraparietal sulcus (IPS). However, its precise role remains a matter of debate. While some authors ... [more ▼]
One of the most consistently activated regions during verbal short-term memory (STM) tasks is the left intraparietal sulcus (IPS). However, its precise role remains a matter of debate. While some authors consider the IPS to be a specific store for serial order information, other data suggest that it serves a more general function of attentional focalization. In the current fMRI experiment, we investigated these two hypotheses by presenting different verbal STM conditions that probed recognition for word identity or word order and by assessing functional connectivity of the left IPS with distant brain areas. If the IPS has a role of attentional focalization, then it should be involved in both order and item conditions, but it should be connected to different brain regions, depending on the neural substrates involved in processing the different types of information (order versus phonological/orthographic) to be remembered in the item and order STM conditions. We observed that the left IPS was activated in both order and item STM conditions but for different reasons: during order STM, the left IPS was functionally connected to serial/temporal order processing areas in the right IPS, premotor and cerebellar cortices, while during item STM, the left IPS was connected to phonological and orthographic processing areas in the superior temporal and fusiform gyri. Our data support a position considering that the left IPS acts as an attentional modulator of distant neural networks which themselves are specialized in processing order or language representations. More generally, they strengthen attention-based accounts of verbal STM. [less ▲]Detailed reference viewed: 112 (15 ULg)
Left Main Coronary Dissection after Mild Chest Trauma. Favorable Evolution with Fibrinolytic and Surgical Therapies
; Limet, Raymond ; Trotteur, Geneviève et al
in CHEST (1988), 93(1), 213-4
A 32-year-old woman had acute anterior myocardial infarction after a mild chest trauma (automobile accident). Unstable angina recurred shortly after admission, and extensive dissection of the left ... [more ▼]
A 32-year-old woman had acute anterior myocardial infarction after a mild chest trauma (automobile accident). Unstable angina recurred shortly after admission, and extensive dissection of the left coronary artery was demonstrated. Medical therapy including systemic fibrinolysis was started but clinical stabilization and good long-term result was achieved only by aortocoronary bypass grafting. [less ▲]Detailed reference viewed: 6 (0 ULg)
Left ventricular apex-dimension loops in acute myocardial infarction.
Pierard, Luc ; ;
in The American journal of cardiology (1984), 54(6), 526-9
Apex-dimension loops may provide useful information in patients with acute myocardial infarction because incoordinate contraction and relaxation can be demonstrated. The method could allow assessment of ... [more ▼]
Apex-dimension loops may provide useful information in patients with acute myocardial infarction because incoordinate contraction and relaxation can be demonstrated. The method could allow assessment of the effects of therapeutic interventions. Fifty consecutive patients with AMI in the coronary care unit within 48 hours after the onset of their symptoms were studied. Simultaneous recordings of the echocardiogram and apexcardiogram, which were of an adequate quality for analysis, were obtained in only 7 patients (success rate 14%). In all these patients, incoordinate relaxation was demonstrated. A major practical drawback of the method is the time needed for recording the basic data requiring 2 investigators. Therefore, because of the low success rate and difficulties in obtaining simultaneous recordings, apex-dimension loops are not practical in most patients with acute myocardial infarction. [less ▲]Detailed reference viewed: 2 (0 ULg)
Left ventricular assist device as bridge to liver transplantation in a patient with propionic acidemia and cardiogenic shock.
; ; et al
in Journal of Pediatrics (2011)Detailed reference viewed: 26 (4 ULg)
Left Ventricular Contractile Reserve in Asymptomatic Degenerative Mitral Regurgitation: Evaluation and Impact on Outcome.
Magne, Julien ; ; et al
Conference (2012)Detailed reference viewed: 8 (1 ULg)
Left ventricular contractile reserve in asymptomatic primary mitral regurgitation
Magne, Julien ; ; PIERARD, Luc et al
in European Heart Journal (2013)Detailed reference viewed: 36 (7 ULg)
Left ventricular dyssynchrony and dynamic functional mitral regurgitation: relationship or association?
Pierard, Luc ; Lancellotti, Patrizio
in European Heart Journal (2006), 27(6), 638-640Detailed reference viewed: 6 (2 ULg)
Left ventricular dyssynchrony: a dynamic condition.
Lancellotti, Patrizio ; Moonen, Marie
in Heart Failure Reviews (2011)
Left ventricular dyssynchrony (LVD) is common in heart failure patients with LV systolic dysfunction. Contrary to what it could be expected, LVD is not a stable phenomenon. Various conditions (inducible ... [more ▼]
Left ventricular dyssynchrony (LVD) is common in heart failure patients with LV systolic dysfunction. Contrary to what it could be expected, LVD is not a stable phenomenon. Various conditions (inducible ischemia, exercise, drug administration) may significantly alter the presence and the magnitude of LVD, which could per se modulate response to treatment for heart failure. LVD can be evaluated using validated Doppler-echocardiographic techniques as tissue Doppler imaging. Exercise and dobutamine stress echocardiography can be used tests to unmask LVD. Changes in LV synchronicity during stress test occur independently of inducible ischemia and irrespective of QRS width. The degree of LVD varies substantially from patient to patient. The dynamic increase in LVD represents a strong contributor: (1) to exercise-induced changes in mitral regurgitation, (2) to limitation of stroke volume adaptation during exercise, and (3) to exertional dyspnea. Whether dynamic LVD might independently affect the outcome has not yet been demonstrated. In the setting of CRT, the assessment of dynamic LVD might help patient selection, predict the magnitude of response, and optimize pacing delivery during exercise. Further longitudinal studies are required to confirm the value of assessing dynamic LVD. [less ▲]Detailed reference viewed: 18 (6 ULg)
Left ventricular function at similar heart rates during tachycardia induced by exercise and atrial pacing: an echocardiographic study.
Pierard, Luc ; ; et al
in British heart journal (1987), 57(2), 154-60
M mode echocardiography was used in 10 normal subjects to study left ventricular dimension and function variables at identical heart rates during tachycardia induced by supine bicycle exercise or atrial ... [more ▼]
M mode echocardiography was used in 10 normal subjects to study left ventricular dimension and function variables at identical heart rates during tachycardia induced by supine bicycle exercise or atrial pacing. Echocardiographic data were analysed independently by two observers. The maximum heart rate reached during atrial pacing was lower (mean (1SD) 148 (17) beats/min) than that reached during exercise (mean (1SD) 167 (14) beats/min). The left ventricular end diastolic dimension was greater before supine exercise than before atrial pacing, probably as a result of leg raising. At each graded exercise step the end diastolic dimension remained greater than during atrial pacing and the differences became progressively greater with increasing heart rates. The left ventricular end systolic dimension was not significantly different at each step during the two stresses. During recovery the end systolic dimension was significantly smaller after exercise than at corresponding heart rates induced by atrial pacing. Left ventricular function indices--fractional shortening and peak rates of left ventricular systolic and diastolic dimensional change--were significantly higher during exercise than during atrial pacing and the differences increased with heart rate. It is concluded that the intervention used to change heart rate has an important effect on M mode echocardiographic left ventricular dimensions; indices of left ventricular performance increase progressively during exercise and differ from those measured at the same heart rate during atrial pacing; it is important to consider heart rate, stroke volume, and loading conditions when reference values are used and when the effects of a particular stress are to be interpreted. [less ▲]Detailed reference viewed: 10 (0 ULg)
Left ventricular potentiation at a reduced exercise level: a cause of false-negative radionuclide ventriculograms.
; ; Legrand, Victor et al
in American journal of physiologic imaging (1986), 1(2), 59-66
During exercise radionuclide ventriculography (RVG), many patients cannot maintain peak workload for acquisition of more than a left anterior oblique view. To acquire further views, the workload may have ... [more ▼]
During exercise radionuclide ventriculography (RVG), many patients cannot maintain peak workload for acquisition of more than a left anterior oblique view. To acquire further views, the workload may have to be reduced. In this study of 16 normals and 20 patients with coronary disease, the workload at peak exercise was reduced by approximately 40%. By paired t-test analysis, there was a rise in the left ventricular ejection fraction (LVEF) in patients with coronary disease from the peak exercise workload to the reduced workload level (postpeak) (52.4 +/- 15.3 to 59.3 +/- 13.7, P = .0001). There was also improvement in LVEF in the normals at the postpeak workload (71.3 +/- 11.7 to 75.1 +/- 13.7, P = .05). Of five coronary disease patients with exercise-induced wall motion abnormalities, four returned to baseline motion at the reduced exercise levels. Partial workload reduction can lead to an increase in LVEF and improvement in wall motion and thus, may result in false-negative studies. [less ▲]Detailed reference viewed: 2 (0 ULg)
Left ventricular preload-adjusted maximal power: Clinically useful marker of LV contractility ?
; Tchana-Sato, Vincent ; et al
in Circulation (2003, October 28), 108(17, Suppl. S), 396-396Detailed reference viewed: 15 (1 ULg)
Left ventricular regional function and maximal exercise capacity in aortic stenosis.
DULGHERU, Raluca Elena ; ; DAVIN, Laurent et al
in European Heart Journal - Cardiovascular Imaging (2016)
AIMS: The objective assessment of maximal exercise capacity (MEC) using peak oxygen consumption (VO2) measurement may be helpful in the management of asymptomatic aortic stenosis (AS) patients. However ... [more ▼]
AIMS: The objective assessment of maximal exercise capacity (MEC) using peak oxygen consumption (VO2) measurement may be helpful in the management of asymptomatic aortic stenosis (AS) patients. However, the relationship between left ventricular (LV) function and MEC has been relatively unexplored. We aimed to identify which echocardiographic parameters of LV systolic function can predict MEC in asymptomatic AS. METHODS AND RESULTS: Asymptomatic patients with moderate to severe AS (n = 44, aortic valve area <1.5 cm2, 66 +/- 13 years, 75% of men) and preserved LV ejection fraction (LVEF > 50%) were prospectively referred for resting echocardiography and cardiopulmonary exercise test. LV longitudinal strain (LS) of each myocardial segment was measured by speckle tracking echocardiography (STE) from the apical (aLS) 4-, 2-, and 3-chamber views. An average value of the LS of the analysable segments was provided for each myocardial region: basal (bLS), mid (mLS), and aLS. LV circumferential and radial strains were measured from short-axis views. Peak VO2 was 20.1 +/- 5.8 mL/kg/min (median 20.7 mL/kg/min; range 7.2-32.3 mL/kg/min). According to the median of peak VO2, patients with reduced MEC were significantly older (P < 0.001) and more frequently females (P = 0.05). There were significant correlations between peak VO2 and age (r = -0.44), LV end-diastolic volume (r = 0.35), LV stroke volume (r = 0.37), indexed stroke volume (r = 0.32), and E/e' ratio (r = -0.37, all P < 0.04). Parameters of AS severity and LVEF did not correlate with peak VO2 (P = NS for all). Among LV deformation parameters, bLS and mLS were significantly associated with peakVO2 (r = 0.43, P = 0.005, and r = 0.32, P = 0.04, respectively). With multivariable analysis, female gender (beta = 4.9; P = 0.008) and bLS (beta = 0.50; P = 0.03) were the only independent determinants (r2 = 0.423) of peak VO2. CONCLUSION: In asymptomatic AS, impaired LV myocardial longitudinal function determines reduced MEC. Basal LS was the only parameter of LV regional function independently associated with MEC. [less ▲]Detailed reference viewed: 101 (23 ULg)
Left ventricular torsional dynamics in aortic stenosis: relationship between left ventricular untwisting and filling pressures. A two-dimensional speckle tracking study.
; ; et al
in European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology (2010), 11(5), 406-13
AIMS: The contribution of left ventricular (LV) untwisting to LV suction and early-diastolic filling was previously demonstrated, but this was not yet tested in patients with aortic stenosis (AS). We ... [more ▼]
AIMS: The contribution of left ventricular (LV) untwisting to LV suction and early-diastolic filling was previously demonstrated, but this was not yet tested in patients with aortic stenosis (AS). We sought to assess the relationship between LV untwisting and LV filling pressures in patients with severe AS and normal left ventricular ejection fraction (LVEF) using speckle tracking echocardiography. METHODS AND RESULTS: Sixty-one consecutive patients (66 +/- 9 years) with severe AS, preserved LVEF (63 +/- 6%), and 40 normal subjects (47 +/- 12 years) were prospectively enrolled. A comprehensive echocardiographic examination was performed in all. LV rotation and twisting were assessed using speckle tracking echocardiography. Peak apical back rotation rate, peak LV untwisting rate, and time intervals from QRS onset (ECG) to each of them were measured. Brain natriuretic peptide (BNP) levels were determined in 30 patients. Patients with AS were older than normal subjects (P < 0.001). LV mass, LA volume, LV filling pressures as well as peak apical back rotation rate and time to peak apical back rotation rate were increased in patients (P < 0.05 for all). In patients with AS, both time to peak LV untwisting rate and time to peak apical back rotation rate were significantly related to E/E' ratio and to BNP levels (P < 0.04 for all). CONCLUSION: In patients with severe AS and preserved LVEF, there is a significant relationship between LV untwisting and LV filling pressures, suggesting a role for impaired LV untwisting in the pathophysiology of diastolic dysfunction in this setting. [less ▲]Detailed reference viewed: 20 (3 ULg)
The Legacy of Invention: Determinism and Metafiction in Janet Frame's Mona Minim and the Smell of the Sun
in Ramsey-Kurz, Helga; Ratheiser, Ulla (Eds.) Antipodean Childhoods: Growing Up in Australia and New Zealand (2010)Detailed reference viewed: 15 (1 ULg)
The Legacy of Invention: Determinism and Metafiction in Janet Frame's Mona Minim and the Smell of the Sun
in Journal of Postcolonial Writing (2009), 45(1),
This essay offers a close reading of Mona Minim and the Smell of the Sun, a tale for children often thought to be unique in the corpus of Janet Frame in that its implied reading public compelled the ... [more ▼]
This essay offers a close reading of Mona Minim and the Smell of the Sun, a tale for children often thought to be unique in the corpus of Janet Frame in that its implied reading public compelled the author to keep her distance from her usual preoccupation with the great negative themes of twentieth-century consciousness. Yet Frame’s declaration in an interview that this was her favourite among her own published books should alert us to the possibility that thematic continuities subterraneously connect it to the rest of the work. In particular, the exploration of animal life encouraged by the genre can be seen to be paradigmatic of her interest in alternative ontologies and to encode the concern with creativity which is a touchstone of her entire output. Typically, too, the figure of the artist – in this case, of the story-teller – is invested with a redemptive value for the beleaguered individual, and cannot be separated from a metafictional mode of representation which is possibly unexpected in what purports to be a simple fairy tale. [less ▲]Detailed reference viewed: 96 (13 ULg)
Legal Aid in Belgium and The Netherlands : Convergences and Differences between Two Institutional Systems
Schoenaers, Frédéric ; Adelaire, Kathleen ; et al
in Hubeau, Bernard; Terlouw, Ashley (Eds.) Legal Aid in the Low Countries (2014)
Since the end of the first decade of the 21st century in Belgium, there has frequently been fierce debate between the world of the politician and that of the lawyer. These debates focus on the secondary ... [more ▼]
Since the end of the first decade of the 21st century in Belgium, there has frequently been fierce debate between the world of the politician and that of the lawyer. These debates focus on the secondary legal aid offered citizens in the low income bracket or in a specific social category. On the one hand, lawyers criticise the low rates they can charge when representing their legal aid clients. According to the members of the bar, the system of remuneration is unfavourable since the lawyers believe that the amounts they receive per hour of work provided fall well below the break-even point. On the other hand, the world of politics has noticed an increase in the volume of litigation which results in increases in budget which in turn becomes uncontrollable. All in all, this raises the question of financing secondary legal aid, which in many continental European countries is considered a citizen’s acquired right (Cappeletti and Garth, 1978, Cappeletti, 1972), or has even been recognised by constitutions since it is one of the fundamental pillars of the guarantee to (relatively) equal access to justice (Parker, 1999). Drawing on this observation of lack of budgetary control in Belgium, we ask the question of whether other institutional contexts perform better (Regan 1999; Driesen et al., 2006). [less ▲]Detailed reference viewed: 48 (12 ULg)
LEGAL CERTAINTY v LEGAL PRECISION. Some thoughts on comparative law
in Fundamina : A Journal of Legal History (2010), 16-1(2010), 121-129Detailed reference viewed: 75 (6 ULg)
A Legal Framework for Plant Biostimulants and Agronomic Fertiliser Additives in the EU - Report to the European Commission, DG Enterprise & Industry
; ; et al
Report (2014)Detailed reference viewed: 81 (7 ULg)
Legal mobilisation and environmental activism in Wallonia (Belgium): where is Environmental Justice?
Conference (2013, September 07)
Environmental justice (EJ) is an important field of research in the USA (Mohai and Bryant 1992, Schlosberg 1999, Bullard 2000, Pellow 2000, Agyeman 2002, Kurtz 2003, Holifield 2009) as well as a framework ... [more ▼]
Environmental justice (EJ) is an important field of research in the USA (Mohai and Bryant 1992, Schlosberg 1999, Bullard 2000, Pellow 2000, Agyeman 2002, Kurtz 2003, Holifield 2009) as well as a framework for grassroots movements and activists who seek to defend their rights to a healthy environment. Environmental inequalities, as they are commonly called in Europe (Emelianoff 2006, Cornut, Bauler et al. 2007, Walker and Eames 2008, Faburel 2012, Walker 2012), are a growing field of research but they are not seen as a specific frame for action and collective mobilisation in Belgium. The use of legal mobilisation as a strategy to fight environmental inequalities in Wallonia (Belgium) is discussed in this paper. I propose to examine access to justice in the field of environmental protection and to link it to considerations in terms of environmental justice, that is to say cases in which groups see themselves as victims of a disproportionate burden of environmental bads (such as exposure to pollution, vicinity to industrial plants, or waste dumps). This paper explores (1) how environmental NGOs and activists can mobilise the law to denounce environmental conflicts and inequalities providing insights into an environmental inequalities perspective on access to justice in Belgium. It also offers an innovative approach to environmental inequalities and justice in Belgium (2) by asking: how is EJ conceived and integrated in environmental research and litigation? Starting on the premise of a weak literature and scholarship on environmental inequalities, I will propose some new avenues for research on these topics in Belgium. For this paper, empirical evidence is based, on the one hand, on legal texts and litigation in Belgium and, on the other hand, on open-ended interviews with stakeholders in Wallonia – main political parties, environmental NGOs, legal practitioners, trade unions, and public institutions. [less ▲]Detailed reference viewed: 48 (2 ULg)