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See detailPDX:PBX complexes are required for normal proliferation of pancreatic cells during development.
Dutta, S.; Gannon, M.; Peers, Bernard ULg et al

in Proceedings of the National Academy of Sciences of the United States of America (2001), 98(3), 1065-70

The homeobox factor PDX-1 is a key regulator of pancreatic morphogenesis and glucose homeostasis; targeted disruption of the PDX-1 gene leads to pancreatic agenesis in pdx-1(-/-) homozygotes. Pdx-1 ... [more ▼]

The homeobox factor PDX-1 is a key regulator of pancreatic morphogenesis and glucose homeostasis; targeted disruption of the PDX-1 gene leads to pancreatic agenesis in pdx-1(-/-) homozygotes. Pdx-1 heterozygotes develop normally, but they display glucose intolerance in adulthood. Like certain other homeobox proteins, PDX-1 contains a consensus FPWMK motif that promotes heterodimer formation with the ubiquitous homeodomain protein PBX. To evaluate the importance of PDX-1:PBX complexes in pancreatic morphogenesis and glucose homeostasis, we expressed either wild-type or PBX interaction defective PDX-1 transgenes under control of the PDX-1 promoter. Both wild-type and mutant PDX-1 transgenes corrected glucose intolerance in pdx-1 heterozygotes. The wild-type PDX-1 transgene rescued the development of all pancreatic lineages in pdx-1(-/-) animals, and these mice survived to adulthood. In contrast, pancreata from pdx-1(-/-) mice expressing the mutant PDX-1 transgene were hypoplastic, and these mice died within 3 weeks of birth from pancreatic insufficiency. All pancreatic cell types were observed in pdx-1(-/-) mice expressing the mutant PDX-1 transgene; but the islets were smaller, and increased numbers of islet hormone-positive cells were noted within the ductal epithelium. These results indicate that PDX-1:PBX complexes are dispensable for glucose homeostasis and for differentiation of stem cells into ductal, endocrine, and acinar lineages; but they are essential for expansion of these populations during development. [less ▲]

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See detailPE teachers’ competencies: which ones are considered as the most important and where are they acquired?
Cloes, Marc ULg; Laraki, Nadine; Piéron, Maurice

Poster (2004, August)

It is well accepted that teacher prepration is a long term process during which a large array of competencies are progressively developed. Since 2001, in the French Community of Belgium, a decree lists ... [more ▼]

It is well accepted that teacher prepration is a long term process during which a large array of competencies are progressively developed. Since 2001, in the French Community of Belgium, a decree lists the competencies that teachers should develop to achieve their role within the educational system. This study aimed to identify competencies taht PE teachers consider as important and to determine, from their point of view, in which context these competencies are developed. [less ▲]

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See detailPeach latent mosaic viroid detected for the firts time on almond trees in Tunisia
Fekih Hassen, I.; Roussel, S.; Kummert, J. et al

in Plant Disease (2005), 89

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See detailPearls and pitfalls: Electrophysiology for primary headaches
MAGIS, Delphine ULg; Vigano, Alessandro; SAVA, Simona Liliana ULg et al

in Cephalalgia : An International Journal of Headache (2013)

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See detailPeasant responses to agricultural land conversion and mechanism of rural social differentiation in Hung Yen province, Northern Vietnam
Nguyen Thi, Dien; Vu Dinh, Ton; Lebailly, Philippe ULg

Conference (2011)

Agricultural accumulation has been one of the main source determined the social differentiation in Vietnamese countryside. The complexities of agrarian changes under the post - socialist industrialization ... [more ▼]

Agricultural accumulation has been one of the main source determined the social differentiation in Vietnamese countryside. The complexities of agrarian changes under the post - socialist industrialization with high rate of agricultural land conversion in recent context reveal the new forms of capital accumulation and social differentiation. This research investigates how land conversion process to industrial zones and clusters affected to the way that different groups of peasant households accumulate their resources. The study was carried out in 3 districts of Hung Yen province from 2006 to 2010. The study results are as follows: first, the land conversion to industrialization has impact on not only the decline of household landholdings but also the changes value of land which are the sources of social conflicts and informal land transfer. Second, in the context of land conversion to industrialization with tiny plots of land, low return from agricultural production and more opportunities of non-farm activities, even when non-farm employment is very profitable, peasant households are not likely to give up their land but maintaining agricultural production for not only their basic and secure livelihood but also for their identity. Third, among the affected peasant groups, the households with non-farm background tend to be in better position in engaging to high - earning activities. They are likely the rich peasants in opposed to the poor group with farming background and lost more than 50% of their agricultural land. This research has showed that the industrialization policies have to deal with the proportion of agricultural land would be transferred for industrialization zones and other measures in order to limit the conflicts as well as the social differentiation in countryside. [less ▲]

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See detailThe peasants in turmoil: Khmer Rouge, state formation and the control of land in northwest Cambodia
Diepart, Jean-Christophe ULg; Dupuis, David

in The Journal of Peasant Studies (2014), 41(4), 445468

Over the past 15 years, northwest Cambodia has seen dramatic agrarian expansion away from the central rice plain into the peripheral uplands fuelled by peasant in-migration. Against this background, we ... [more ▼]

Over the past 15 years, northwest Cambodia has seen dramatic agrarian expansion away from the central rice plain into the peripheral uplands fuelled by peasant in-migration. Against this background, we examine the nature of relations between the peasantry and the state. We first show the historical continuities of land control processes and how the use of violence in a post-conflict neoliberal context has legitimised ex-Khmer Rouge in controlling land distribution. Three case studies show the heterogeneity of local level sovereignties, which engage the peasants in different relations with authority. We examine how these processes result in the construction of different rural territories along the agricultural frontier and argue that, in this region of Cambodia, the struggles between Khmer Rouge and neoliberal modes of land control are central to state formation processes. [less ▲]

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See detailPeatlands of Wallony (S-Belgium)
Frankard, Philippe; Ghiette, Pascal; Hindryckx, Marie-Noëlle ULg et al

in Suoseura - Finnish Peatland Society (1998), 49(2), 33-47

Various types of peatlands are present in Wallony: raised bogs, oligotrophic and rich fens, wet heaths, marshy woodlands. Many areas have been degraded by past and recent human activities. Much attention ... [more ▼]

Various types of peatlands are present in Wallony: raised bogs, oligotrophic and rich fens, wet heaths, marshy woodlands. Many areas have been degraded by past and recent human activities. Much attention is now devoted to their protection, scientific study and ecological management. Besides their exceptional biological and ecological interest, they are among the last natural spaces in a very urbanised country like Belgium. [less ▲]

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See detailLa peau : miroir de la santé
Peeters, Dominique ULg; Remy, Isabelle

in Proceedings of "Congrès SAVAB" (2006, February)

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See detailLa peau de l'acromégale.
Hermanns-Lê, Trinh ULg; QUATRESOOZ, Pascale ULg; Arrese Estrada, Jorge ULg et al

in Dermatologie Actualité (2003), 75

L'acromégalie est l'expression clinique d'une hypersécrétion chronique de l'hormone de croissance dont la source est, dans la plupart des cas, un adénome hypophysaire. Son diagnostic est souvent posé ... [more ▼]

L'acromégalie est l'expression clinique d'une hypersécrétion chronique de l'hormone de croissance dont la source est, dans la plupart des cas, un adénome hypophysaire. Son diagnostic est souvent posé tardivement, car les signes cliniques se développent de façon insidieuse. [less ▲]

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See detailLa peau dite sèche du patient diabétique.
Uhoda, Emmanuelle ULg; Debatisse, B.; Paquet, Philippe ULg et al

in Revue Médicale de Liège (2005), 60(5-6), 560-3

Rough skin or xerosis, known by the laity as dry skin, results from a defect in the stratum corneum desquamation which normally remains imperceptible. This condition is negatively influenced by winter ... [more ▼]

Rough skin or xerosis, known by the laity as dry skin, results from a defect in the stratum corneum desquamation which normally remains imperceptible. This condition is negatively influenced by winter climatic conditions. Atopic dermatitis and trophic changes related to post-menopause, ageing, diabetes mellitus, as well as other endrocrine and metabolic disturbances are also involved in this process. Xerosis can be improved at various degrees by emollients, humectants, hydrating agents and squamolytic agents. [less ▲]

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See detailLa peau du patient sous chimiothérapie anticancéreuse.
PIERARD, Gérald ULg; PAQUET, Philippe ULg; FRANCHIMONT, Claudine ULg et al

in Dermatologie Actualité (2011), 124

Des effets cutanés indésirables peuvent survenir lors de chimiothérapies anticancéreuses. La morbidité peut être handicapante à des degrés divers. Certaines manifestations sont graves comme celles ... [more ▼]

Des effets cutanés indésirables peuvent survenir lors de chimiothérapies anticancéreuses. La morbidité peut être handicapante à des degrés divers. Certaines manifestations sont graves comme celles rencontrées lors de nécroses épithéliales et/ou vasculaires étendues. D’autres sont spécifiques à l’agent administré. Tel est le cas pour des éruptions acnéiformes induites par les antagonistes de l’EGFR. Dans la grande majorité des cas, les altérations de la structure de la couche cornée et de ses fonctions se résument seulement à un état de xérose. Parfois aussi, les altérations ne se décèlent qu’à l’examen histopathologique sans répercussion clinique manifeste. Pour chaque patient concerné, il convient d’identifier avec précision les effets indésirables de la chimiothérapie anticancéreuse afin de choisir les moyens les plus adéquats pour prévenir leur aggravation et les traiter au mieux. L’apport de l’examen dermatopathologique standard et fonctionnel est précieux au stade du diagnostic. [less ▲]

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See detailLa peau et l'obésite.
Martalo, Oriane; Pierard, Claudine ULg; Scheen, André ULg et al

in Revue Médicale de Liège (2003), 58(2), 73-6

Obesity is a chronic multifactorial disease representing a major health problem. Among its consequences, diverse facets of the cutaneous physiology are altered. Some dermatoses are also more prevalent ... [more ▼]

Obesity is a chronic multifactorial disease representing a major health problem. Among its consequences, diverse facets of the cutaneous physiology are altered. Some dermatoses are also more prevalent. The most typical ones are acanthosis nigricans, skin tags, signs of hyperandrogeny, striae distensae, stasis acroangiodermatitis, leg ulcers, lymphoedema and intertrigo. [less ▲]

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See detailLa peau et le temps de la menopause.
Thirion, Laurence; Franchimont, Claudine ULg; Arrese Estrada, Jorge ULg et al

in Revue Médicale de Liège (2006), 61(3), 159-62

The estrogen deficit occurring at menopause manifests itself under various modalities in the diverse organs and their functions. Skin does not escape this global involutive process. In addition to the ... [more ▼]

The estrogen deficit occurring at menopause manifests itself under various modalities in the diverse organs and their functions. Skin does not escape this global involutive process. In addition to the effects of chronological ageing, sunlight exposure and other environmental and endogenous stimuli, the climacteric appears to exert some dramatic consequences on skin biology and aspect. The epidermis, its adnexae and the dermis are altered by this process. The epidermis may become xerotic and exhibits altered functions. The dermis thins out and its elasticity decreases in concert with the decline in bone mass. The skin microcirculation is impaired. These aspects are some of the better-worked out skin climacteric changes of which in turn seem to be stabilized or in part reversible with hormone replacement therapy (HRT). [less ▲]

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See detailLa peau et ses nuances ethniques.
Flagothier, Caroline ULg; Pierard, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2005), 60 Suppl 1

Ethnic (racial) differences exist for a series of physiological skin characteristics. Colour is responsible for typology and resistance to ultraviolet irradiations. Other differences have also been ... [more ▼]

Ethnic (racial) differences exist for a series of physiological skin characteristics. Colour is responsible for typology and resistance to ultraviolet irradiations. Other differences have also been reported for the transepidermal water loss, the size and cohesion of corneocytes, the vascular reactiviy, the biomechanical properties, the pH, the lipidic content, the superficial microflora and the structure of mast cell granules. [less ▲]

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See detailLa peau et ses principales neurocristopathies.
Quatresooz, Pascale ULg; Vandenbossche, Géraldine ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2008), 63(5-6), 354-8

The neurocristopathies encompass genetic disorders targeting some structures originating from the neural crest development. Hence, skin is affected by some clinical manifestations of these disorders. This ... [more ▼]

The neurocristopathies encompass genetic disorders targeting some structures originating from the neural crest development. Hence, skin is affected by some clinical manifestations of these disorders. This review covers the main aspects found in neurofibromatosis, tuberous sclerosis, incontinentia pigmenti, neurocutaneous melanoblastosis, basal cell naevomatosis and the epidermal naevus syndrome. [less ▲]

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See detailLa peau et son horloge chronobiologique au quotidien.
Henry, Frédérique ULg; Arrese Estrada, Jorge ULg; Claessens, N. et al

in Revue Médicale de Liège (2002), 57(10), 661-5

Some cutaneous functions of importance are governed by periodical variations according to the nycthemeral timing. Similarly to other organs, the skin is under the influence of a coherent organisation of ... [more ▼]

Some cutaneous functions of importance are governed by periodical variations according to the nycthemeral timing. Similarly to other organs, the skin is under the influence of a coherent organisation of circadian and nythemeral rhythms modulating various biological cycles which usually display a wide amplitude. The cutaneous biorhythms in humans suggest that during daylight the skin boosts diverse protective functions with regard to environmental threats. In the evening and at night, the skin increases its renewal and diverse metabolic processes. Biorhythms in the skin which are in line with the organism's needs, merit to be recognized. Chronophysiology, chronopathology and clinical chronopharmacology may help reach optimal therapeutic decisions. [less ▲]

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See detailLa peau infectée par des bactéries au cours des hémopathies malignes.
FRANCHIMONT, Claudine ULg; SZEPETIUK, Grégory ULg; LESUISSE, Marianne et al

in Dermatologie Actualité (2012), 133

Detailed reference viewed: 8 (2 ULg)