Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailNo Increase in Plasma Histamine During Paf-Induced Airway Obstruction in Allergic Asthmatics
Louis, Renaud ULg; Bury, Thierry ULg; Corhay, Jean-Louis ULg et al

in CHEST (1993), 104(3), 806-10

To investigate the possible role of mast cell or basophil histamine release in mediating platelet-activating factor (PAF) airway obstruction, we studied the effect of inhaled PAF (30 micrograms, single ... [more ▼]

To investigate the possible role of mast cell or basophil histamine release in mediating platelet-activating factor (PAF) airway obstruction, we studied the effect of inhaled PAF (30 micrograms, single dose) on plasma histamine, bronchial caliber, and leukocyte and platelet counts in six patients with mild or moderate allergic asthma (mean age, 27 +/- 1.3 years; mean FEV1, 95 +/- 5 percent of predicted; mean PC20 methacholine, 1.46 +/- 0.36 mg/ml). Specific conductance (SGaw) FEV1, FEF25-75 percent, differential leukocyte and platelet counts, and plasma histamine (radioimmunoassay) were measured before and 5, 10, 15, and 20 min after PAF inhalation. Mean basal plasma histamine level was 0.28 +/- 0.04 ng/ml. Inhalation of PAF caused a fall in SGaw peaking at 5 min (43 +/- 9 percent) and a fall in FEV1 and FEF25-75 peaking at 10 min (19 +/- 10 percent and 30 +/- 13 percent, respectively). There was also a rapid and transient fall in circulating neutrophils at 5 min (from 3,096 +/- 204/mm3 to 2,551 +/- 158/mm3, p < 0.05) followed by a rebound neutrophilia. In contrast, plasma histamine level did not change significantly at any time measured. Conversely in the same asthmatics, a rapid rise in plasma histamine level (from 0.29 +/- 0.03 ng/ml at baseline to 0.53 +/- 0.06 ng/ml at 5 min; p < 0.01) was observed after an allergenic challenge (Dermatophagoides pteronyssinus) causing a fall in FEV1 peaking at 10 min (22 +/- 4 percent). Thus, inhaled PAF may induce airway obstruction and neutropenia in asthmatics without any significant change of plasma histamine level. These results indicate that it is unlikely that lung mast cells or basophils degranulate during PAF-induced bronchoconstriction. [less ▲]

Detailed reference viewed: 10 (1 ULg)
Peer Reviewed
See detailNo increased insulin sensitivity after a single intravenous administration of a recombinant human tumor necrosis factor receptor: Fc fusion protein in obese insulin-resistant patients.
Paquot, Nicolas ULg; Castillo, M. J.; Lefebvre, Pierre ULg et al

in Journal of Clinical Endocrinology and Metabolism (2000), 85(3), 1316-9

Inhibition of tumor necrosis factor (TNF)-alpha results in a marked increase in insulin sensitivity in obese rodents. We investigated the influence of a TNF antagonist [Ro 45-2081, a recombinant fusion ... [more ▼]

Inhibition of tumor necrosis factor (TNF)-alpha results in a marked increase in insulin sensitivity in obese rodents. We investigated the influence of a TNF antagonist [Ro 45-2081, a recombinant fusion protein that consists of the soluble TNF-receptor (p55) linked to the Fc portion of human IgG1] on insulin sensitivity of patients with android obesity. Seven patients (five women and two men; mean +/- SD age, 41 +/- 4 yr; body mass index, 36.1 +/- 4.7 kg/m2; waist to hip ratio, 0.99 +/- 0.11) were studied (three patients with normal glucose tolerance and four patients with impaired glucose tolerance or mild diabetes; all were hyperinsulinemic). Each patient underwent two consecutive euglycemic hyperinsulinemic glucose-clamp tests: 48 h after injection of placebo and 48 h after a single i.v. injection of 50 mg Ro 45-2081. In both tests, steady-state plasma glucose and insulin levels were similar. Insulin-mediated glucose disposal (2.23 +/- 0.74 vs. 2.38 +/- 0.99 mg/kg(-1) x min(-1)) and glucose metabolic clearance rate (2.28 +/- 0.85 vs. 2.48 +/- 1.03 mL/kg(-1) x min(-1)) were similar after placebo and after the drug. Indirect calorimetry showed no difference in substrate oxidation rates between the two experimental conditions. In conclusion, under the conditions of this study, no improvement in insulin sensitivity was observed in obese insulin-resistant patients following a single i.v. administration of a recombinant TNF receptor: Fc fusion protein. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailNo influence of 20 and 400 mu T 50 Hz magnetic field exposure on cognitive function in humans
Delhez, Marie; Legros, Jean-Jacques ULg; Crasson, Marion ULg

in Bioelectromagnetics (2004), 25(8), 592-598

The aim of the present study was to investigate cognitive effects of a continuous, vertical extremely low frequency (ELF) magnetic field (MF) of 20 and 400 muT 50 Hz in healthy young men during ... [more ▼]

The aim of the present study was to investigate cognitive effects of a continuous, vertical extremely low frequency (ELF) magnetic field (MF) of 20 and 400 muT 50 Hz in healthy young men during performance on cognitive tests. Thirty-two volunteers (20-30 years old, mean 22.6 +/- 2.2 years) participated in this double blind study. The test protocol consisted of a set of tests: divided attention, flexibility, memory updating, digit span, digit span with articulary suppression, and time perception. The total duration of the exposure was 65 min. Participants were assigned four sessions: three conditions in the helmet (sham exposure, 20 and 400 muT) and one condition out of the helmet (to control the expectancy effect). No effect of MF exposure was observed on performance. Bioelectromagnetics 25:592-598, 2004. (C) 2004 Wiley-Liss, Inc. [less ▲]

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailNo interest for a second close infiltration of platelet-rich plasma to treat upper patellar tendinopathies
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Buhler, Frédéric et al

in European Journal of Physical and Rehabilitation Medicine (2014, May), 50(Suppl. 1 to No. 3), 21639-002-

Background: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Background: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. The aim of this study was to evaluate whether 2 infiltrations of PRP proves more effective than a single treatment. Methods: Twenty patients suffering from jumper’s knee for over than 3 months were enrolled into the study and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. Conclusion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups after a follow-up period of 3 months. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. [less ▲]

Detailed reference viewed: 45 (4 ULg)
Full Text
Peer Reviewed
See detailNo interest for a second closely-timed infiltration of platelet-rich plasma (PRP) to treat jumper’s knees
Kaux, Jean-François ULg; CROISIER, Jean-Louis ULg; Forthomme, Bénédicte ULg et al

in Radmann, A; Hedenborg, S; Tsolakidis, E (Eds.) 20th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE - BOOK OF ABSTRACTS (2015, June)

Introduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Introduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. The aim of this study was to evaluate whether 2 infiltrations of PRP proves moreeffective than a single treatment. Methods: Twenty patients suffering from chronic jumper’s knee were enrolled into our prospective, randomized and comparative study of level 2, and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups.Discussion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups at short to mid term. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. References: Kaux JF, Croisier JL, Bruyere O, Rodriguez de la Cruz C, Forthomme B, Brabant G et al. One injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper’s knee. J Sports Med Phys Fitness. 2014 Jun 19. [Epub ahead of print]. Kaux JF, Croisier JL, Forthomme B, Le Goff C, Buhler F, Savanier C et al. Using platelet-rich plasma to treat jumper’s knees: exploring the effect of a second closely-timed infiltration. J Sci Med Sport. Submitted. Kaux JF, Bruyère O, Croisier JL, Forthomme N, Le Goff C, Rohr N et al. One-year follow-up of platelet-rich plasma infiltration to treat chronic upper patellar tendinopathies. Acta Orthop Belg. In press. [less ▲]

Detailed reference viewed: 29 (2 ULg)
Full Text
See detailNo Laughing Matter
Maiorano, Diego ULg

Article for general public (2013)

Detailed reference viewed: 51 (1 ULg)
Full Text
Peer Reviewed
See detailNo major month to month variation in free testosterone levels in aging mates. Minor impact on the biological diagnosis of 'andropause'
Tancredi, Annalisa ULg; Reginster, Jean-Yves ULg; Luyckx, Françoise ULg et al

in Psychoneuroendocrinology (2005), 30(7), 638-646

BACKGROUND: The measurement of bioavailable testosterone (BT) or free testosterone (FT) levels is currently considered the gold standard for the diagnosis of androgen deficiency in elderly men. While the ... [more ▼]

BACKGROUND: The measurement of bioavailable testosterone (BT) or free testosterone (FT) levels is currently considered the gold standard for the diagnosis of androgen deficiency in elderly men. While the impact of age on circulating testosterone levels (total, bioavailable and free) has been strongly documented, the existence of seasonal variations in testosterone levels remains debated. OBJECTIVE: We investigated whether seasonal variations in serum calculated free testosterone (cFT) levels may translate into variations in the prevalence of low testosterone levels. Diagnosis was on the basis of biochemical determinations and was cross-checked with the prevalence of clinical signs and symptoms of 'andropause', as assessed by the Androgen Deficiency in Aging Males (ADAM) questionnaire. METHODS: The study recruited 5028 men aged 50 years and over from September 2000 to January 2003. Their serum FT levels were assessed and they completed the French ADAM test. Men were considered eugonadal when cFT was > or =70 ng/l. The ADAM test was scored as described originally. The prevalence of 'andropause', diagnosed by the two methods, was compared throughout the year, on a month by month basis. RESULTS: The percentage of subjects with cFT levels below 70 ng/l increased significantly with age (P<0.001). Serum cFT levels (mean [SD]) varied significantly with the month of sampling (P<0.0001), the highest (88.1 [30.2] ng/l) and lowest (76.9 [28.0] ng/l) mean values occurring in April and in October, respectively. Conversely, the prevalence of testosterone deficiency (cFT<70 ng/l) reached a peak in October (45.7%) and a nadir in April (29.7%). Although the prevalence of 'andropause', based on the ADAM questionnaire, increased significantly with age (P<0.0001), no influence of the month of the year was noticed. CONCLUSIONS: Our results confirm a progressive age-related decline in FT levels. The monthly variations in serum FT values, observed throughout the year, do not show a major seasonal rhythm in elderly community-dwelling males, since the magnitude of the variations (<15%) remains marginal. This slight variation may, however, have an impact on the number of elderly men diagnosed with Partial Androgen Deficiency in Aging Males (PADAM). [less ▲]

Detailed reference viewed: 37 (5 ULg)
See detailThe NO Martian Nightglow observed with the SPICAM UV Spectrometer and comparison with a one-dimensional model.
Cox, Cédric ULg; Saglam, A.; Gérard, Jean-Claude ULg et al

Conference (2007, April)

Observations in the 108-317 nm wavelength range have been performed with the SPICAM ultraviolet spectrometer aboard the Mars Express (MEX) mission. SPICAM has observed the ultraviolet nightglow emission ... [more ▼]

Observations in the 108-317 nm wavelength range have been performed with the SPICAM ultraviolet spectrometer aboard the Mars Express (MEX) mission. SPICAM has observed the ultraviolet nightglow emission in the δ (190-240 nm) and γ (225-270 nm) bands of nitric oxide (Bertaux et al. 2005). This emission arises from the recombination between O(3P) and N(4S) atoms that are produced on the day side to form NO in the night side. We present a summary of the night limb observations performed during the MEX mission. In particular, we describe the variability of the brightness and peak altitude. We find that the altitude of maximum emission varies between 55 and 90 km and the brightness is in the range 0.2 to 4.5 kR. We compare these observations with the results of a chemical-diffusive atmospheric model which solves the continuity equation for O, N(4S) and NO continuity equation using the finite volume method on one dimensional grid. The eddy coefficient, whose value is very uncertain, is a free parameter adjusted to match the observational data. [less ▲]

Detailed reference viewed: 22 (1 ULg)
Full Text
See detailNo performance reduction at the present northern edge of Ambrosia artemisiifolia L. invasion range
Ortmans, William ULg; Chauvel, Bruno; Monty, Arnaud ULg et al

Conference (2014, May 05)

Plant populations at range edges may exhibit reduction of performances and fitness. In the case of biological invasions, such a reduction could be associated with a slowing down of the spread and explain ... [more ▼]

Plant populations at range edges may exhibit reduction of performances and fitness. In the case of biological invasions, such a reduction could be associated with a slowing down of the spread and explain the non-naturalization of a species outside its present invasion range. Common ragweed (Ambrosia artemisiifolia L.) is an ideal model to investigate such processes, since it is invasive in France but not naturalized in northern countries, such as Belgium and the Netherlands. In this study, we test if the performances of ragweed populations vary among different invasion zones. Three populations were selected in each of four invasion zones in Western Europe: 1) French invasion area; 2) northern and 3) southern invasion edges; and 4) outside the invasion area (Belgium and Netherlands). Field performances (growth, reproduction, stress resistance) were recorded on 25 plants per population. Furthermore, the competition by the native flora was assessed around each plant. Generalized Linear Models were used to compare performance among invasion zones and populations, with competition as covariate. Regressions were also performed to assess the influence of climatic data on population performances. No evidence of decreasing performances was found at the edges of the invasion area, neither outside of it, suggesting that the invasion front has the potential to keep going northwards. Competition by native flora had a significant impact on stress resistance, but did not decrease reproduction or growth. These results are discussed in the light of other ongoing experiments in Belgium. [less ▲]

Detailed reference viewed: 36 (12 ULg)
Full Text
Peer Reviewed
See detailNo serologic evidence for emerging Schmallenberg virus infection in dogs (Canis domesticus)
Garigliany, Mutien-Marie ULg; Desmecht, Daniel ULg; Bayrou, Calixte ULg et al

in Vector Borne & Zoonotic Diseases (2013), 13(11), 1-4

Schmallenberg virus, a novel orthobunyavirus, is spreading among ruminants, especially sheep and cattle throughout Europe. To determine the risk for domestic dog infection, we conducted a survey among ... [more ▼]

Schmallenberg virus, a novel orthobunyavirus, is spreading among ruminants, especially sheep and cattle throughout Europe. To determine the risk for domestic dog infection, we conducted a survey among cases referred to the university Companion Animal Clinic to assess possible seroconversion. No evidence of transmission to dogs was detected. [less ▲]

Detailed reference viewed: 61 (13 ULg)
Peer Reviewed
See detailNo significant effect of an "atraumatic" needle on incidence of post-lumbar puncture headache or traumatic tap.
Lenaerts, M.; Pepin, J. L.; Tombu, S. et al

in Cephalalgia : An International Journal of Headache (1993), 13(4), 296-7

We compared the incidence of post-lumbar puncture headache and of red blood cells in the first CSF sample (traumatic tap) in 35 inpatients punctured with a standard 20 G Yale needle and in 26 patients ... [more ▼]

We compared the incidence of post-lumbar puncture headache and of red blood cells in the first CSF sample (traumatic tap) in 35 inpatients punctured with a standard 20 G Yale needle and in 26 patients punctured with Sprotte's "atraumatic" needle. No significant difference was found between the two groups in incidence of headache or in frequency of traumatic taps. [less ▲]

Detailed reference viewed: 9 (2 ULg)
Peer Reviewed
See detailNo simian Plasmodium detected in populations living in the equatorial rainy forest of the Democratic Republic of Congo
Mvumbi makaba, Dieudonné; Bobanga Lengu, Thierry; Kayembe Ntumba, Jean-Marie et al

Poster (2014, April 03)

Background Malaria remains the most deadly parasitic disease to date, especially in sub-Saharan Africa, which comprises the majority of cases collected per year. It has long been accepted that four ... [more ▼]

Background Malaria remains the most deadly parasitic disease to date, especially in sub-Saharan Africa, which comprises the majority of cases collected per year. It has long been accepted that four species of Plasmodium (P. falciparum, P. vivax, P. malariae and P. ovale) were responsible for the disease in humans. But quite recently, a fifth species, Plasmodium Knowlesi, has been identified as naturally infecting humans. Indeed, known for decades as naturally parasitizing the monkey Macaca fascicularis, P. knowlesi has long been confused, in terms of its evolutionary stage, with P. malariae or P. falciparum, which it resembles morphologically and it was not possible to properly differentiate them until the advent of molecular biology. To date, P. Knowlesi has only been identified in Southeast Asia and a similar phenomenon of natural transmission of simian plasmodium to humans has not been reported elsewhere. We therefore conducted this study to investigate the possible transmission of simian plasmodium to humans in populations living near the rainforest of the Democratic Republic of Congo (DRC) where several species of primates lives. Methods & Materials Three villages (Wenji-Secli, Bongonde, and Bolenge) in the Province of Ecuador (North-eastern DRC) were selected because of their geographical location. Blood samples spotted on filter paper were collected from 100 people randomly taken in each village. Two successive RT- PCR were performed. A first one using a single probe able to diagnose all plasmodium spp. and a second using four species-specific probes for the diagnosis of the four conventional human plasmodium species. Positivity in the first RT- PCR with negativity in the second RT- PCR would suggest the presence of plasmodium species other than the four conventional. Results P. falciparum was correctly identified in 44.6 % of samples. No other species of human plasmodium or not has been identified. Conclusion This preliminary study did not detect the presence of simian plasmodium in human populations living in the rainforest of the DRC. Studies with larger samples and with more advanced techniques should still be conducted. Keywords: Malaria, simian plasmodium, DR Congo [less ▲]

Detailed reference viewed: 67 (7 ULg)
Full Text
See detailNo utopianism nor solidarism. Is a materialist and critical understanding of association possible ?
Frère, Bruno ULg

Conference (2012)

From Engels to Adorno and Horkheimer, to Althusser or Bourdieu everything seems to occur as if criticism in its main variation – the Marxist approach – had worked to feed a principal way of thinking ... [more ▼]

From Engels to Adorno and Horkheimer, to Althusser or Bourdieu everything seems to occur as if criticism in its main variation – the Marxist approach – had worked to feed a principal way of thinking: individuals (workers, proletarians, social actors, etc.) unconsciously reproduce the social structures of capitalism which alienate them. They accept the conditions enforced on them and no longer seek to rebel against a world which substantially impoverish their labor, their soul and their creativity. Even worse: they ensure the reproduction of the system by seeking to engage in mass consumption at any price. There is little doubt that Marx was not wrong to point out, with the concept of alienation, the inhuman working conditions in which the nineteenth century proletariat was, and which a huge part of the workers still have to face all around the world nowadays. Should the worker-consumer only be seen as a scatterbrain being who unconsciously reproduces, to use Bourdieu’s language, the conditions of his domination? My intention here is not to put Marx in the dock, since he is, I am sure, an author whose work has remained of unequalled power for over a century. However, I would like to try and show that by dint of favouring almost exclusively the concept of alienation in his work, there is a considerable risk that only a negative path for criticism can emerge from it. It is that initial heart of criticism which was Marx’s thinking and which has irrigated the whole twentieth century from the Frankfurt School to French critical sociology that I would like to put into perspective by suggesting a new agenda for critical research that I would characterize as, for now and for lack of a better term, positive. This agenda of research is in its early days. Nonetheless, in my opinion, a theoretical base should be given to it straight away. The following pages will try to establish it by notably drawing on the main theoretician of libertarian anarchism, Marx’s rival on socialist theory, Proudhon. However, I would like to insist on the fact that the purpose is not to truly turn the latter against Marx . Because I think that Marx must remain a topical issue, I rather wish to demonstrate that, at the cradle of criticism, right next to him, there is an equally – or even more? – Materialist position which could be pertinently combined to the criticism of alienation . This position might be helpful to highlight, here and now, possibilities of emancipation through labor which are not exclusively conditioned by the “Grand Soir”. Proudhon’s work is certainly philosophically and economically weaker than Marx’s. However, Proudhon is very interesting in the way he manages to see in a “laboring” man something else than a slave-laboring animal deprived of subjectivity by capitalism and who only exists as a production tool. In that way, criticism, if any, may be considered as positive [less ▲]

Detailed reference viewed: 16 (1 ULg)
See detailThe NO Venus nightglow: SPICAV observations and implications on transport in the lower thermosphere
Gérard, Jean-Claude ULg; Cox, Cédric ULg; Bertaux, J.-L.

Conference (2010, June 22)

A new set of 725 NO limb profiles has been analyzed. The profiles have been deconvolved and inverted to get volume emission rates. Updates mean VER peak altitude is 115 km, in excellent agreement with PV ... [more ▼]

A new set of 725 NO limb profiles has been analyzed. The profiles have been deconvolved and inverted to get volume emission rates. Updates mean VER peak altitude is 115 km, in excellent agreement with PV results obtained 30 years ago. The corresponding average vertical intensity is 1.2 kR. The altitude of emission occurs at a higher altitude near the bright spot region than at larger distances (by about 7 km). The location of the statistical bright spot is the same as observed with PV (that is shifted dawnward by 2 hrs and slightly south of AS point). The nightside mean vertical intensity is between 0.4 and 1.8 kR, which brackets the values derived from the limb profiles. These results, coupled with other airglow measurements, provide constraints on global atmospheric circulation and vertical transport [less ▲]

Detailed reference viewed: 12 (0 ULg)