Scientific and Technological Payloads Aboard the B3LSat CubeSat of the QB50 Network

in Proceedings of the 2nd IAA Conference on University Satellite Missions and Cubesat Workshop (2013)

Scientific basis of physical therapy and rehabilitation in the management of patients with osteoarthritis

in Reginster, Jean-Yves; Pelletier, J-P; Martel-Pelletier, J (Eds.) et al Osteoarthritis: Clinical and experimental aspects (1999)

Scientific Dating of Architectural Ceramics Applied to Medieval Building Archaeology: Application to the church Notre-Dame-sous-Terre (Mont-Saint-Michel, France)

in British Brick Society Information (2008)

Scientific Imagination and Magical Ingredients: Towards an Anthropology of Technofood

Conference (2010, August)

2010 promises to be a pivotal year for producers of food, since the European Food Safety Authority is to publish a list of accepted health claims made on industrial food products. The production of such a ... [more ▼]

2010 promises to be a pivotal year for producers of food, since the European Food Safety Authority is to publish a list of accepted health claims made on industrial food products. The production of such a list, however, goes not without trouble. In the first section, this paper will outline the controversies and scientific uncertainties accompanying the development of a technological food category (allegedly) providing physical or psychological health benefits 'beyond basic nutrition'. In the second section, food will be looked at through the lens of power. Throughout human history, different authorities have prescribed what one should (not) eat. What is at stake then, when health claims and food become technological? Finally, it will be argued that an anthropology of 'technofood' is possible, by translating the discourse of market, competitiveness and 'optimized health' in terms of techno-scientific imagination, magical thinking and (bio)power. [less ▲]

The Scientific Representation of Temporal Stratification

in Semiotics 2009 Proceeding Volume of 34th Annual Semiotic Society of America (SSA) Meeting (2010)

Scintigraphic visualization of intrathecal liposome biodistribution.

in Acta Anaesthesiologica Scandinavica (1997), 41(1 Pt 1), 25-34

BACKGROUND: Liposomes containing local anaesthetics have been administered intrathecally and in the epidural space. Poor attention has been given to the pharmacokinetics of liposomes as drug carriers ... [more ▼]

BACKGROUND: Liposomes containing local anaesthetics have been administered intrathecally and in the epidural space. Poor attention has been given to the pharmacokinetics of liposomes as drug carriers. Therefore, we observed the biodistribution of liposomes after intrathecal injection in rats by scintigraphic imaging during 24 h. METHODS: We administered 99mTc-labeled multilamellar (MLV) and small unilamellar vesicles (SUV) of defined size and volume dispersities into the cerebrospinal fluid at the lumbar level. Those vesicles were free of contamination by radiolabeled colloids as visualized by light and electron microscopy and of neurotoxic products from phosphatidylcholine hydrolysis and peroxidation, both during the preparation process and after 24 h incubation in cerebrospinal fluid at 37 degrees C in vitro. RESULTS: SUV immediately diffused from the lumbar site of injection to the head and were cleared between 1 and 24 h after injection. MLV were cleared more slowly from the spinal space and appeared in the head region 1 h after injection where they accumulated up to 24 h. These differences were explained in terms of vesicle sizes and volumes. SUV with 0.05 micron diameters were rapidly absorbed into the blood through the arachnoid granulations. In contrast, particles larger than the upper size limit of the arachnoid granulations permeability (+/- 8 microns) could accumulate in the head with a slow elimination rate. CONCLUSION: This difference in clearance from the intrathecal space outlines the importance of defining the size of the liposomes, the distribution of a tracer or a drug inside the liposomal preparation, the chemical stability and the absence of toxic degradation products of liposome formulations before clinical use. [less ▲]

Scintigraphical V/Q ratios analysis in healthy and disearsed horses: a theoretical approach

in Pflügers Archiv : European Journal of Physiology (1995), 429

Scintigraphy

in Lekeux, Pierre (Ed.) Equine Respiratory Diseases (2001)

Scintimammography with technetium-99m methoxyisobutylisonitrile: results of a prospective European multicentre trial.

in European Journal of Nuclear Medicine (1998), 25(4), 375-85

The aim of the trial was to determine the diagnostic accuracy of scintimmammography with technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) in the detection of primary breast cancer and to verify its ... [more ▼]

The aim of the trial was to determine the diagnostic accuracy of scintimmammography with technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) in the detection of primary breast cancer and to verify its clinical usefulness. A total of 246 patients with a suspicious breast mass or positive mammogram were included in this prospective European multicentre trial. At 5 min and 60 min (optional) p.i. two lateral prone images were acquired for 10 min each; 30 min p.i. one anterior image was acquired for 10 min. There were 253 lesions (195 palpable and 58 non-palpable), in respect of which histology revealed 165 cancers and 88 benign lesions. Institutional and blinded read results were correlated to core laboratory histopathology results obtained during excisional biopsy. Diagnostic accuracy for the detection of breast cancer was calculated per lesion. The overall sensitivity and specificity of blinded read scintimammography were 71% and 69%, respectively. For palpable lesions, the sensitivity of blinded read and institutional read scintimammography was 83% and 91%, respectively. Sensitivity was not dependent on the density of the breast tissue. Invasive ductal and invasive lobular cancers showed similar sensitivity. The sensitivity and specificity of mammography were 91% and 42%, respectively, and did not depend on the tumour size. In 60% of false-negative mammograms, 99mTc-MIBI was able to diagnose malignancy (true-positive). High-quality imaging with 99mTc-MIBI has a high diagnostic accuracy for the detection of primary breast cancer. Used as a complementary method, scintimammography with 99mTc-MIBI can help to diagnose breast cancer at an earlier stage in patients with dense breasts. [less ▲]

Sclérodermie en coup de sabre et hémiatrophie faciale de Perry-Romberg: A propos d'un cas

in 30ème Congrès de l'Association des Pédiatres de Langue Française (1993)