RXS J1131-1231: a lensed host galaxy at z = 0.66

in Claeskens, J. F.; Sluse, D.; Riaud, Pierre (Eds.) et al Proceedings of the Joint European and National Astronomy Meeting (http://www.astro.ulg.ac.be/RPub/Colloques/JENAM/proceedings/proceedings.html) (2005)

The RYR1 g.1843C > T mutation is associated with the effect of the IGF2 intron3-g.3072G > A mutation on muscle hypertrophy

in Animal Genetics (2007), 38(1), 67-71

Muscle growth is a complex phenomenon regulated by many factors, whereby net growth results from the combined action of synthesis and turnover. In pigs, two quantitative trait nucleotides (QTN) are known ... [more ▼]

Muscle growth is a complex phenomenon regulated by many factors, whereby net growth results from the combined action of synthesis and turnover. In pigs, two quantitative trait nucleotides (QTN) are known to have an important influence on muscle growth and fat deposition: one QTN is located in the ryanodine receptor 1 (RYR1) gene (RYR1 g.1843C > T) and the other, a paternally expressed QTN, is in the insulin-like growth factor 2 (IGF2) gene (IGF2 intron3-g.3072G > A). The mutation in IGF2 abrogates in vitro interaction with a repressor, which leads to a threefold increase of IGF2 expression in post-natal muscle. The family of the calpains, a family of Ca2+-sensitive muscle endopeptidases, and their specific inhibitor calpastatin play an important role in post-natal protein degradation, also influencing muscle and carcass traits. This study investigated the possible interactions between the genotypes of the RYR1 and IGF2 QTN on IGF2 expression. Samples were taken from several muscles and from pigs at several ages, and messenger RNA expression levels were measured using a real-time quantification assay. IGF2 expression in m. longissimus dorsi of animals with mutations in both IGF2 and RYR1 was significantly lower than in animals that inherited the IGF2 mutation but were homozygous wildtype for RYR1. [less ▲]

Rythme affolé des ventricules dû à la fibrillation des oreillettes. Physiologie du faisceau auriculo-ventriculaire

in Archives Internationales de Physiologie (1905), II

Rythme évolutiof du Gravettien oriental

in Montet-White, Anta; Palma di Cesnola, Arturo; Valoch, Karel (Eds.) The Upper Palaeolithic. Colloquium XII: The Origin of The Gravettian (1996)

The key-sequence of Moldavian sites (Cosautsi, Mitoc, Molodova V) gives a frame for general evolution of Gravettian technology. It can be tentatively related to Central Europe chronology (Willendorf II ... [more ▼]

The key-sequence of Moldavian sites (Cosautsi, Mitoc, Molodova V) gives a frame for general evolution of Gravettian technology. It can be tentatively related to Central Europe chronology (Willendorf II) as well as Eastern Europe (Kostenki). Both chronological tendencies and regional trends can be detected. [less ▲]

Rythmes du temps, Astronomie et Calendriers

Book published by De Boeck Université (2000)

Rythmes sécrétoires dans la maladie de Cushing

Scientific conference (1989, November 25)

S Phase Dependence and Involvement of Nf-Kappab Activating Kinase to Nf-Kappab Activation by Camptothecin

in Biochemical Pharmacology (2001), 62(5), 603-16

Camptothecin (CPT) and derivatives are topoisomerase I poisons currently used as anticancer drugs. Their cytotoxicity is maximal for cells in S phase. Using asynchronous and S phase-synchronized HeLa ... [more ▼]

Camptothecin (CPT) and derivatives are topoisomerase I poisons currently used as anticancer drugs. Their cytotoxicity is maximal for cells in S phase. Using asynchronous and S phase-synchronized HeLa cells, we showed that both the nuclear factor-kappaB (NF-kappaB) activation and its transcriptional activity, induced by CPT treatment, are enhanced in S phase cells. After CPT treatment, NF-kappaB activation reached a maximum within 2-3 hr and was still detectable after 24 hr. The nature of the complex evolved with time, forming mostly p50/p65 after 2 hr to almost exclusively p52 after 24 hr. In HeLa cells, the different steps of the induction were readily observable in S phase synchronized cells, whereas they were barely noticeable in a randomly growing cell population. The signal progressed through the activation of the IKK complex, the phosphorylation of IkappaBalpha, and the degradation of phosphorylated-IkappaBalpha and -IkappaBbeta. The stable expression of wild-type HA-tagged-IkappaBalpha or mutated HA-tagged-IkappaBalpha (S32,36A) allowed us to confirm the essential role of Ser32 and Ser36. NF-kappaB-activating kinase (NIK) could play a role upstream of the IKK complex, as the transient expression of a kinase inactive mutant NIK(K429,430A) abolished the activation of NF-kappaB by CPT. A kinase inactive mutant of mitogen-activated protein/ERK kinase kinase 1 (MEKK1), another kinase susceptible of acting upstream of the signalsome, did not. Cytotoxicity studies with clonal populations expressing different amounts of wild-type or mutated IkappaBalpha revealed that the overexpression of wild-type IkappaBa in large amount increases the sensitivity of HeLa cells to CPT more efficiently than a lower level of expression of non-phosphorylable IkappaBalpha. [less ▲]

S'auto-former aux TIC

Poster (2009, June)

Poster présentant deux dispositifs de formation visant la maitrise des TIC et la méthodologie (didactique des TIC) qui les sous-tendent.

S’engager dans la Jeunesse étudiante catholique dans les années quarante

in Hudon, Raymond (Ed.) Jeunesses et politique - tome II Mouvements et engagements depuis les années trente (1994)

S'engager dans la lecture : un investissement au service des compétences.

in Actes du 3e Congrès des chercheurs en éducation (2004)