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See detailAsthme aigu grave: une affection qui demeure redoutable.
D'Orio, Virginie ULg; Ghuysen, Alexandre ULg; Lambermont, Bernard ULg

in Revue Médicale de Liège (2009), 64(7-8), 377-81

Severe exacerbations of asthma can be life-threatening if not aggressively treated. Despite the publication of therapeutic guidelines developed by experts in this field and people education programs ... [more ▼]

Severe exacerbations of asthma can be life-threatening if not aggressively treated. Despite the publication of therapeutic guidelines developed by experts in this field and people education programs, early recognition and characterization of patients at risk for fatal asthma remain scarce. We report the case of a young lady suffering from acute exacerbation of asthma responsible for intensive care admission with long term mechanical ventilation due to the lack in initial appropriate care. [less ▲]

Detailed reference viewed: 145 (26 ULg)
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See detailAsthme et bêta2-agonistes de longue durée d'action
Bury, Thierry ULg; Kayambe, JM; Radermecker, Maurice ULg

in Médecine et Hygiène (1994), 52

Detailed reference viewed: 3 (0 ULg)
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See detailAsthme et hyperréactivité bronchique non spécifique
Louis, Renaud ULg; Kayembe, J. M.; Radermecker, Maurice ULg

in Acta Clinica Belgica (1994), 49(3-4), 148-57

Bronchial hyperresponsiveness is a hallmark of asthma although it can also be present, to a lesser extent, in other diseases. The level of bronchial responsiveness depends on immuno-inflammatory processes ... [more ▼]

Bronchial hyperresponsiveness is a hallmark of asthma although it can also be present, to a lesser extent, in other diseases. The level of bronchial responsiveness depends on immuno-inflammatory processes modifying the functional status of airway smooth muscle as well as the structure of the bronchial wall. The responsiveness toward a direct constricting pharmacological agent is poorly correlated to the one toward an indirect constricting agent or a physical stimulus which cause airway obstruction through a more complex mechanism. Transversal studies show a relationship between the severity of asthma and the level of methacholine airway responsiveness. Long term treatment with corticoids can reduce the bronchial hyperresponsiveness of asthmatics. [less ▲]

Detailed reference viewed: 68 (1 ULg)
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See detailAsthme et tabac.
Gusbin, N.; Garzaniti, N.; Louis, Renaud ULg

in Revue Médicale de Liège (2006), 61(2), 81-6

Roughly 40% of asthmatics are or have been smokers. These smoking asthmatics have been largely overlooked in the past. Tobacco is today considered as a risk factor for asthma and it seems that smoking ... [more ▼]

Roughly 40% of asthmatics are or have been smokers. These smoking asthmatics have been largely overlooked in the past. Tobacco is today considered as a risk factor for asthma and it seems that smoking asthmatics exhibit a different phenotype as compared to non smoking asthmatics. The inflammatory substrate differs widely, not only with respect to the type of cells present in the airways, but also with respect to the mediators brought into play. On the clinical point of view the asthma of smokers is also more severe that in non smokers, both at the symptomatic and the functional level. The asthma severity in smokers is partly linked to a resistance to inhaled corticoids, the cornerstone of maintenance treatment in asthma. This makes urgent to assess alternative treatment to inhaled corticoids for this asthma phenotype, but also emphasizes the need to support smoking cessation in asthmatics. [less ▲]

Detailed reference viewed: 86 (5 ULg)
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See detailL'asthme ou le spectre asthmatique chez l'enfant
Battisti, Oreste ULg; Zigabe Mushamuka, Serge ULg

Learning material (2013)

ce travail présente les aspects cliniques, investigationnels, thérapeutiques et éducatifs du spectre asthmatique chez l'enfant

Detailed reference viewed: 78 (21 ULg)
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See detailAsthme ou psychose
Gauthier, Jean-Marie ULg

in Asthme, allergies : l'approche psychosomatique (1989), 69

Detailed reference viewed: 26 (3 ULg)
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See detailAsthme réfractaire : mécanismes sous-jacents, diagnostics et nouvelles approches thérapeutiques.
Manise, Maïté ULg; Louis, Renaud ULg

in Revue Médicale de Liège (2008), 63(7-8), 494-499

There has been a recent increase in the prevalence of asthma worldwide. Most cases can be satisfactorily managed with a combination of inhaled corticoids and bronchodilators. However, some 10% of patients ... [more ▼]

There has been a recent increase in the prevalence of asthma worldwide. Most cases can be satisfactorily managed with a combination of inhaled corticoids and bronchodilators. However, some 10% of patients remain symptomatic despite high doses of inhaled corticosteroids and long-acting β-2 agonists. They represent a heterogeneous group consisting of those who are either undertreated, or really refractory to current available treatment. [less ▲]

Detailed reference viewed: 75 (19 ULg)
See detailL'asthme sévère
Cataldo, Didier ULg; Dupont, Lieven

Book published by ViVio (2009)

Detailed reference viewed: 11 (2 ULg)
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See detailL'asthme: une maladie complexe mettant en jeu facteurs environnementaux et terrain genetique.
LOUIS, Renaud ULg; SCHLEICH, FLorence ULg; Corhay, Jean-Louis ULg et al

in Revue Médicale de Liège (2012), 67(5-6), 286-91

Asthma is a complex disease highly dependent of environmental exposure and genetic background. Through linkage analysis, positional cloning and genome wide association studies, novel asthma genes have ... [more ▼]

Asthma is a complex disease highly dependent of environmental exposure and genetic background. Through linkage analysis, positional cloning and genome wide association studies, novel asthma genes have come out such as ADAM-33 or ORMLD3. Important environmental factors include allergenic exposure, pollutants and especially particulate matters, tobacco, aerosol exposure, viral infections and level of exposure to endotoxin. The effects of environmental factors are modulated by the genetic sequence and numerous single nucleotide polymorphisms (SNPs). Recently, it has also become clear that environmental factors may alter gene expression by DNA methylation or histone methylation/acetylation without changing the gene sequence and thereby changing asthmatic phenotype. [less ▲]

Detailed reference viewed: 67 (6 ULg)
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See detailL'asthme: une maladie de tout l'arbre aerien.
Tillie-Leblond, I.; Louis, Renaud ULg; Magnan, A. et al

in Revue des Maladies Respiratoires (2009), 26(8), 851-8

Inflammation and remodelling are constant features of asthma. They are present throughout the whole bronchial tree, even in the small airways (less than 2 mm). The inflammatory cell infiltrate and ... [more ▼]

Inflammation and remodelling are constant features of asthma. They are present throughout the whole bronchial tree, even in the small airways (less than 2 mm). The inflammatory cell infiltrate and structural changes are, in most cases, identical. However, in severe asthma, nocturnal asthma and fatal asthma, the cellular infiltrate in the distal airways is more intense and the number of activated cells is increased. In fatal asthma there are major alterations in the distal airways involving the smooth muscle and the bronchial epithelium, and mucus hypersecretion leading to distal airway plugging. Thus the histopathological changes in the distal airways contribute to the most severe stages of asthma and should be targeted by treatment. Currently the non-invasive tools that reflect inflammation are unable to assess these changes in the distal airways. [less ▲]

Detailed reference viewed: 46 (5 ULg)
Peer Reviewed
See detailAstreinte et droit du travail
Maréchal, Benoît ULg

Article for general public (2008)

The possibility for the Belgian judge to make a restriction order is limited in Belgian Labour Law under article 1385bis of the judicial code. The Author try to define this limitation and the possibility ... [more ▼]

The possibility for the Belgian judge to make a restriction order is limited in Belgian Labour Law under article 1385bis of the judicial code. The Author try to define this limitation and the possibility to make a restriction order under Belgian Labour law. [less ▲]

Detailed reference viewed: 202 (15 ULg)
See detailAstrobiologie
Javaux, Emmanuelle ULg; Claeys, Philippe; Dehant, Véronique et al

Learning material (2008)

powerpoint sur MyULg, notes partielles imprimées

Detailed reference viewed: 32 (11 ULg)
See detailAstrobiologie : origine, évolution et distribution de la vie dans l’univers.
Javaux, Emmanuelle ULg

Conference given outside the academic context (2010)

Detailed reference viewed: 7 (2 ULg)
See detailAstrobiologie cours-conférence du Collège Belgique (ARB)
Javaux, Emmanuelle ULg; Wilmotte, Annick ULg; Claeys, Philippe et al

Learning material (2009)

cours enregistrés sur le site de l'ARB (http://www.academieroyale.be/)

Detailed reference viewed: 35 (8 ULg)
See detailAstrobiologie et exploration du système solaire
Javaux, Emmanuelle ULg; Lebreton, Jean-Pierre; Chicarro, Augustin et al

Conference given outside the academic context (2005)

Detailed reference viewed: 5 (2 ULg)
See detailL’astrobiologie
Javaux, Emmanuelle ULg

Scientific conference (2003)

Detailed reference viewed: 1 (0 ULg)
See detaill'astrobiologie: origine, évolution et distribution de la vie dans l'univers
Javaux, Emmanuelle ULg

Conference given outside the academic context (2006)

Detailed reference viewed: 8 (1 ULg)
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See detailAstrobiology : origin, evolution and distribution of life in the universe
Javaux, Emmanuelle ULg

in CAPAS Bulletin de l'Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique. Sciences (2008)

Detailed reference viewed: 15 (0 ULg)
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See detailAstrobiology : origin, evolution and distribution of life in the universe.
Javaux, Emmanuelle ULg

in CAPAS comptes-rendus (2007)

Detailed reference viewed: 6 (3 ULg)