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Peer Reviewed
See detailPatient morbidity after 2 different surgical protocols to treat miller class I recession in the anterior maxilla: A Comparaitive Ramdomized Control Trial.
SALHI, Leila ULg; ROMPEN, Eric ULg; LECLOUX, Geoffrey ULg et al

Conference (2012, June)

Aim: The objective of this study was to compare two different periodontal plastic surgery procedures to treat Miller’s class I recession: a coronally advanced flap (control group) versus the pouch ... [more ▼]

Aim: The objective of this study was to compare two different periodontal plastic surgery procedures to treat Miller’s class I recession: a coronally advanced flap (control group) versus the pouch technique (test group), both of which were associated with connective tissue graft. Methods: Forty consecutive patients were included, with 20 patients being allocated for each group. The level of recession coverage, the keratinised tissue quantity, gingival aesthetics (PES), and postoperative outcomes were assessed for a follow-up period of 6 months. Results: After 6 months, both techniques allowed for the excellent mean root coverage of 96.3 ± 12.1% in the control group and of 91.3 ± 17.6% in the test group. Complete root coverage was achieved in 89.5% (17/19) and 79% (15/19) of the recession cases in the control and the test groups, respectively. A significant increase in keratinised tissue height (p=0.0011) was observed in the test group. A significant improvement in the pink aesthetic score was found in the 2 groups, but gingival texture displayed significantly better results in the test group (p<0.0001). No significant difference between the 2 groups was found in terms of the morbidity outcomes. Pain killer consumption was similar in the 2 groups and significantly decreased over time. [less ▲]

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Peer Reviewed
See detailPatient morbidity after socket preservation using a connective tissue graft versus a bilayer collagen matrix: Preliminary results of a comparative Randomized Control Trial.
FERNANDEZ AYORA, Alberto ULg; VANHOUTTE, Vanessa ULg; LECLOUX, Geoffrey ULg et al

Poster (2012, June)

INTRODUCTION AND AIM: The present randomized controlled trial compared socket preservation procedures using bovine hydroxyapatite (Bio-Oss®, Geistlich, Switzerland) covered with a connective tissue graft ... [more ▼]

INTRODUCTION AND AIM: The present randomized controlled trial compared socket preservation procedures using bovine hydroxyapatite (Bio-Oss®, Geistlich, Switzerland) covered with a connective tissue graft (CT) versus a bilayer collagen membrane (CM) (Mucograft®, Geistlich, Switzerland), placed from buccal to palatal in split-thickness pouches in order to seal the extraction site and to potentially thicken the buccal mucosa. The aim of this present abstract was to evaluate post-operative complications and patient-centered outcomes of the two independent surgical protocols. METHODS: This randomized controlled trial included 26 patients (16 female, 10 male) aged from 20 to 69 years (mean: 42.6, SD: 12). 26 teeth were extracted atraumatically and the 2 distinct surgical protocols were applied randomly. Patients filled out a VAS form 1 week after the surgery to evaluate their level of discomfort and post-operative pain. Drug intakes as well as complications were also recorded. RESULTS: No statistical significant differences were found between the 2 groups in terms of post-operative complications (bleeding) and post-operative pain. The consumption of painkillers after the surgery decreased over time but was similar in the two groups. CONCLUSION: According to the preliminary results of the present RCT, none of both protocols seemed to induce significant post-operative pain and discomfort. There was no difference between the two procedures regarding post-operative complications and patient centered outcomes. [less ▲]

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See detailPatient out-of-pocket contributions related to hip fracture hospital costs in Belgium
Hiligsmann, Mickaël ULg; Gathon, Henry-Jean ULg; Bruyère, Olivier ULg et al

in Osteoporosis International (2011, March), 22(Suppl.1), 333

Detailed reference viewed: 50 (23 ULg)
Peer Reviewed
See detailLe patient polyvasculaire. Etude rétrospective de 4200 patients vasculaires opérés entre 1980 et 1986
Van Damme, Hendrik ULg; Creemers, Etienne ULg; Dekoster, Guy ULg et al

in Acta Chirurgica Belgica (1988), 88(2, Mar-Apr), 111-9

Polyvascular patients. Among a consecutive series of 4200 patients submitted to vascular surgery, a group of 292 people operated on, in at least two anatomically and physiologically different sites, is ... [more ▼]

Polyvascular patients. Among a consecutive series of 4200 patients submitted to vascular surgery, a group of 292 people operated on, in at least two anatomically and physiologically different sites, is individualized as polyvascular patients. A subgroup is characterized by simultaneous procedures in two separated fields; 32 have benefited in the same time from carotid and coronary procedures, i.e., 0.6% of all coronary patients and 2% of all carotid patients. The carotid-coronary group exhibited a more severe anatomical disease both in the carotid and the coronary vasculatures. Apart from simultaneously operated patients, others were sequentially treated over a 7 years period: people with carotid (25%) or visceral (40%) arterial disease were more prone to become polyvascular. Polyvascular patients differ from monovascular patients in that hypertension is more frequent and more severe, mean cholesterol level higher and incidence of severe hypercholesterolemia more frequent. [less ▲]

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See detailPatient preference for eletriptan 80 mg versus subcutaneous sumatriptan 6 mg: results of a crossover study in patients who have recently used subcutaneous sumatriptan
Schoenen, Jean ULg; Pascual, J.; Rasmussen, S. et al

in European Journal of Neurology (2005), 12(2), 108-117

This current randomized, open-label, crossover study evaluated preference for oral eletriptan 80 mg compared with subcutaneous sumatriptan 6 mg (suma-sc) amongst patients (n = 311) meeting IHS criteria ... [more ▼]

This current randomized, open-label, crossover study evaluated preference for oral eletriptan 80 mg compared with subcutaneous sumatriptan 6 mg (suma-sc) amongst patients (n = 311) meeting IHS criteria for migraine who had recently used suma-sc, and found it well tolerated. Three attacks were treated on each study medication. Assessment of subjective preference was evaluated, after which patients freely chose which study medication they wished to use to treat each of three additional migraine attacks. A slight majority (50.6%) preferred or greatly preferred eletriptan, whilst 43% preferred suma-sc. When permitted to choose between eletriptan and suma-sc for subsequent treatment, 78% of patients who had preferred eletriptan took eletriptan during the extension phase for all three of their attacks, whilst only 37% of patients who preferred suma-sc took suma-sc for all of their extension-phase attacks (P < 0.05). Secondary efficacy measures showed comparable efficacy for each study medication, except for faster headache response and pain-free rates favor of suma-sc, and a significantly lower recurrence rate on eletriptan (25% vs. 40%; P < 0.05). The results of this study suggest that eletriptan is a strong alternative option for patients who have been prescribed suma-sc. [less ▲]

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See detailPatient Preference in the Management of Postmenopausal Osteoporosis with Bisphosphonates
Reginster, Jean-Yves ULg; Rabenda, Véronique ULg

in Clinical Interventions in Aging (2006), 1(4), 415-23

The leading treatments for postmenopausal osteoporosis are the nitrogen-containing bisphosphonates, which are required long term for optimal benefit. Oral bisphosphonates have proven efficacy in ... [more ▼]

The leading treatments for postmenopausal osteoporosis are the nitrogen-containing bisphosphonates, which are required long term for optimal benefit. Oral bisphosphonates have proven efficacy in postmenopausal osteoporosis in clinical trials, but in practice the therapeutic benefits are often compromised by patients' low adherence. Nonadherence to bisphosphonate therapy negatively impacts outcomes such as fracture rate; fractures are in turn associated with decreased quality of life. The most common reason cited by patients for their nonadherence is that the strict dosing instructions for bisphosphonates are difficult to follow. One aspect of bisphosphonate administration that can be changed is dosing frequency and several studies have evaluated patient preferences for different dosing schedules. Studies have shown a preference for a weekly bisphosphonate regimen versus daily dosing and it has been demonstrated that this preference for reduced dosing frequency impacts on adherence. Ibandronate is the first nitrogen-containing oral bisphosphonate for osteoporosis that can be administered in a monthly regimen and two robust clinical studies demonstrated a strong patient preference for this monthly regimen versus a weekly regimen. It is important that physicians consider patient preference when prescribing treatment for osteoporosis to ensure that the disease is effectively managed for the long-term benefit of the patient. [less ▲]

Detailed reference viewed: 28 (2 ULg)
Peer Reviewed
See detailPatient Safety Course : Morbidity and Mortality Meeting
Nyssen, Anne-Sophie ULg

Conference (2008, May)

Detailed reference viewed: 13 (1 ULg)
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See detailPatient safety indicators
Jacques, Jessica ULg; Gillet, Pierre ULg

Report (2007)

Detailed reference viewed: 46 (10 ULg)
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Peer Reviewed
See detailPatient specific identification of the cardiac driver function in a cardiovascular system model.
Hann, C. E.; Revie, J.; Stevenson, D. et al

in Computer Methods & Programs in Biomedicine (2011)

The cardiac muscle activation or driver function, is a major determinant of cardiovascular dynamics, and is often approximated by the ratio of the left ventricle pressure to the left ventricle volume. In ... [more ▼]

The cardiac muscle activation or driver function, is a major determinant of cardiovascular dynamics, and is often approximated by the ratio of the left ventricle pressure to the left ventricle volume. In an intensive care unit, the left ventricle pressure is usually never measured, and the left ventricle volume is only measured occasionally by echocardiography, so is not available real-time. This paper develops a method for identifying the driver function based on correlates with geometrical features in the aortic pressure waveform. The method is included in an overall cardiovascular modelling approach, and is clinically validated on a porcine model of pulmonary embolism. For validation a comparison is done between the optimized parameters for a baseline model, which uses the direct measurements of the left ventricle pressure and volume, and the optimized parameters from the approximated driver function. The parameters do not significantly change between the two approaches thus showing that the patient specific approach to identifying the driver function is valid, and has potential clinically. [less ▲]

Detailed reference viewed: 13 (2 ULg)
Peer Reviewed
See detailPatient specific model of the cardiovascular system during septic shock
Desaive, Thomas ULg; Chase, J. G.; Lambermont, Bernard ULg et al

in Intensive Care Medicine (2009), 35(suppl. 1), 80

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See detailPatient specific modelling of cardiac muscle activation
Stevenson, D; Hann, CE; Revie, JA et al

in Proceedings of the Health Research Society of Canterbury (HRSC) Clinical Meeting 2010 (2010)

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Peer Reviewed
See detailA patient who survived total colonic ulcerative colitis surinfected by cytomegalovirus complicated by toxic megacolon and disseminated intravascular coagulation
Laurent, S.; Reenaers, Catherine ULg; Detroz, Bernard ULg et al

in Acta Gastro-Enterologica Belgica (2005), 68(2, Apr-Jun), 276-279

The authors report the case of a patient aged 60-year-old who survived ulcerative colitis complicated by toxic megacolon and disseminated intravascular coagulation. This patient was not known for this ... [more ▼]

The authors report the case of a patient aged 60-year-old who survived ulcerative colitis complicated by toxic megacolon and disseminated intravascular coagulation. This patient was not known for this ulcerative colitis and was first hospitalised for a suspicion of diverticulitis. The admission symptoms were fever, abdominal pain and bloody diarrhoea. The evolution was defavorable under antibiotics and sulfasalazine. The patient was readmitted 5 days after he left hospital, and the diagnosis of UC was based on colon biopsy made during the first hospitalisation. A treatment with methylprednisolone was started and the patient worsened day by day with apparition of toxic megacolon and disseminated intravascular coagulation. Subtotal colectomy was performed for degradation of general status and coagulation factors. Pathological findings confirmed ulcerative colitis with toxic megacolon. Cytomegalovirus inclusions were demonstrated on the colonic specimen and confirmed by PCR. In this report the authors discuss the etiology of toxic megacolon and disseminated intravascular coagulation in ulcerative colitis surinfected by cytomegalovirus. Mortality of these pathologies is high necessitating rapid diagnosis of cytomegalovirus infection by sigmoid biopsy. Management requires immunosupression interruption and ganciclovir therapy, or surgery in unsuccessful medical treatment. [less ▲]

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See detailA Patient with Hiv Infection, Cough, Asthenia, and Fever
Mayasi, N.; Chandrikakumari, Kavitha; Mukeba, D. et al

in Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America (2007), 45(5), 662-3559-600

Detailed reference viewed: 20 (10 ULg)
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Peer Reviewed
See detailLe patient, sa famille et l'équipe thérapeutique de l'hôpital de jour: à la recherche d'une alliance
Triffaux, Jean-Marc ULg

in Gonsalves, Pedro (Ed.) Le patient, la famille, l'équipe thérapeutique de l'Hôpital de jour (1994)

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Peer Reviewed
See detailA patient-specific airway branching model for mechanically ventilated patients.
Damanhuri, Nor Salwa; Docherty, Paul D.; Chiew, Yeong Shiong et al

in Computational and mathematical methods in medicine (2014), 2014

Background. Respiratory mechanics models have the potential to guide mechanical ventilation. Airway branching models (ABMs) were developed from classical fluid mechanics models but do not provide accurate ... [more ▼]

Background. Respiratory mechanics models have the potential to guide mechanical ventilation. Airway branching models (ABMs) were developed from classical fluid mechanics models but do not provide accurate models of in vivo behaviour. Hence, the ABM was improved to include patient-specific parameters and better model observed behaviour (ABMps). Methods. The airway pressure drop of the ABMps was compared with the well-accepted dynostatic algorithm (DSA) in patients diagnosed with acute respiratory distress syndrome (ARDS). A scaling factor (alpha) was used to equate the area under the pressure curve (AUC) from the ABMps to the AUC of the DSA and was linked to patient state. Results. The ABMps recorded a median alpha value of 0.58 (IQR: 0.54-0.63; range: 0.45-0.66) for these ARDS patients. Significantly lower alpha values were found for individuals with chronic obstructive pulmonary disease (P < 0.001). Conclusion. The ABMps model allows the estimation of airway pressure drop at each bronchial generation with patient-specific physiological measurements and can be generated from data measured at the bedside. The distribution of patient-specific alpha values indicates that the overall ABM can be readily improved to better match observed data and capture patient condition. [less ▲]

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See detailPatient-specific modelling of cardiovascular dysfunction: Identifying models of pulmonary embolism in pigs
Desaive, Thomas ULg; Revie, J; Hann, CE et al

in Proceedings of the 19th International Conference of the Cardiovascular System Dynamics Society (2010)

Detailed reference viewed: 7 (0 ULg)
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Peer Reviewed
See detailPatient-specific modelling of the cardiovascular system – application to septic shock with a minimal data set
Desaive, Thomas ULg; Chase, J. G.; Starfinger, C. et al

in World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany (2010)

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See detailPatient-ventilator synchrony and tidal volume variability using NAVA and pressure support mechanical ventilation modes
Moorhead, K. T.; Piquilloud, L.; LAMBERMONT, Bernard ULg et al

in Proceedings of the 18th IFAC world congress, 2011 (2011)

Neurally Adjusted Ventilatory Assist (NAVA) is a new ventilatory mode in which ventilator settings are adjusted based on the electrical activity detected in the diaphragm (Eadi). This mode offers ... [more ▼]

Neurally Adjusted Ventilatory Assist (NAVA) is a new ventilatory mode in which ventilator settings are adjusted based on the electrical activity detected in the diaphragm (Eadi). This mode offers significant advantages in mechanical ventilation over standard pressure support (PS) modes, since ventilator input is determined directly from patient ventilatory demand. A comparative study of 22 patients undergoing mechanical ventilation in both PS and NAVA modes was conducted, and it was concluded that for a given variability in Eadi, there is greater variability in tidal volume and correlation between the tidal volume and the diaphragmatic electrical activity with NAVA compared to PS. These results are consistent with the improved patient-ventilator synchrony reported in the literature. © 2011 IFAC. [less ▲]

Detailed reference viewed: 49 (7 ULg)
See detailLes patients acromégales sont-il mal pris en charge? De la mauvaise utilisation des bases de données
Petrossians, Patrick ULg; Tichomirova, M.; Daly, Adrian ULg et al

in 23ème Congrès de la Société Française d'Endocrinologie - Abstract book (2006)

Detailed reference viewed: 23 (1 ULg)