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See detailA New Separable Approximation Scheme for Topological Problems and Optimization Problems Characterized by a Large Number of Design Variables
Duysinx, Pierre ULg; Zhang, Weihong; Fleury, Claude ULg et al

in Olhoff, Niels; Rozvany, Georges I.N. (Eds.) Proceedings of the First World Congress of Structural and Multidisciplinary Optimization (WCSMO1) (1995, May)

This paper is dedicated to a new convex separable approximation for solving optimization problems characterized by a very large number of design variables as in topology design. For such problems, the ... [more ▼]

This paper is dedicated to a new convex separable approximation for solving optimization problems characterized by a very large number of design variables as in topology design. For such problems, the convergence speed can be accelerated if one uses high quality approximation schemes for structural responses. To achieve this task, we propose, here, a new approximation procedure that belongs to the GMMA family. The originality of this new scheme is to rely on an automatic selection procedure of the asymptotes, using only first and zero order information accumulated during the previous iterations. This is possible owing to a diagonal Quasi-Newton update technique. Firstly, the new approximation procedure is validated on classical "benchmarks" of structural optimization. Then, it is compared to other schemes on a typical topology optimization problem. [less ▲]

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See detailNew serological markers in inflammatory bowel disease are associated with complicated disease behavior
Ferrante, M.; Henckaerts, L.; Joossens, M. et al

in Gut (2007), 56(10), 1394-1403

OBJECTIVE: The human androgen receptor (AR) contains a polyglutamine and a polyglycine stretch which are highly polymorphic and are coded respectively by a CAG and GGN repeat in exon 1 of the AR gene ... [more ▼]

OBJECTIVE: The human androgen receptor (AR) contains a polyglutamine and a polyglycine stretch which are highly polymorphic and are coded respectively by a CAG and GGN repeat in exon 1 of the AR gene. Although the in vitro studies indicated a possible effect of the GGN repeat polymorphism on the AR gene transcription and clinical observations suggest that it might modulate the androgen action, its functional significance remains unclear. We wanted to assess whether the GGN repeat affects the serum testosterone levels in healthy men, which is the expected outcome through feedback regulation if it influences androgen action as has been shown to be the case for the CAG repeat. DESIGN AND PATIENTS: A population based cross-sectional cohort study including 1476 healthy young, middle-aged, and elderly men. MEASUREMENT: Testosterone and LH levels were determined by immunoassay; free testosterone (FT) levels were calculated. Genotyping of the GGN repeat was performed using the sequencing technique. RESULTS: The GGN repeat number was significantly associated with circulating testosterone and FT levels (P=0.017 and P=0.013 respectively). However, taking into account that age, body mass index, and CAG are already in the regression model, the GGN repeat could explain only a small part of the variation of both testosterone and FT. CONCLUSION: To our knowledge, this study is the first to demonstrate a significant positive association between the GGN repeat and androgen levels in a large cohort of healthy men. Although the present study thus adds credence to the view that the polyglycine tract in the AR can modulate AR action, this effect appears to be only small so that its clinical relevance remains questionable. [less ▲]

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See detailNew serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis
Deberg, Michelle ULg; Labasse, Alain ULg; Christgau, S. et al

in Osteoarthritis and Cartilage (2005), 13(3), 258-265

Objective: Protein nitration is a prominent feature of inflammatory processes in the joint. We have developed immunoassays specific for a peptide of the alpha-helical region of type II collagen (108 ... [more ▼]

Objective: Protein nitration is a prominent feature of inflammatory processes in the joint. We have developed immunoassays specific for a peptide of the alpha-helical region of type II collagen (108)HRGYPGLDG(116) (Coll 2-1) and its nitrated form (108)HRGY(NO2)PGLDG(116) (Coll 2-1 NO2) in biological fluids. Design: Coll 2-1 and Coll 2-1 NO2 peptides were injected into rabbits. Two antisera (D3 and D37) were selected for their specificity and affinity and used to develop specific immunoassays. Coll 2-1 and Coll 2-1 NO2 were measured in sera of 242 healthy subjects (N), 67 patients with primary knee osteoarthritis (OA) and 19 patients with rheumatoid arthritis (RA). Results: In healthy subjects, Coll 2-1 and Coll 2-1 NO2 concentrations were 125.13 +/- 3.71 nM and 0.16 +/- 0.08 nM, respectively. In OA and RA, Coll 2-1 and Coll 2-1 NO2 serum levels were found to be significantly increased compared to controls of the same range of age (Coll 2-1: OA: 200.80 +/- 8.98 nM, RA: 172.30 +/- 19.05 nM, normal: 126.60 +/- 6.70 nM and Coll 2-1 NO2: OA: 0.26 +/- 0.02, RA: 0.38 +/- 0.05, normal: 0.12 +/- 0.01 nM). Coll 2-1 NO2 levels were significantly more elevated in RA than in OA patients (P < 0.05). As a consequence, the ratio Coll 2-1 NO2/Coll 2-1 was 1.6 times higher in RA than in OA subjects. No relationship was found between the radiological OA severity and the levels of Coll 2-1 and Coll 2-1 NO2 in serum. Coll 2-1 NO2, but not Coll 2-1, was correlated with C-reactive protein in the sera of OA and RA patients. Conclusions: The determination of both Coll 2-1 and Coll 2-1 NO2 in serum of arthritic patients seems to be a promising useful tool for the detection of oxidative-related cartilage degradation episode. Further, these markers could be helpful for monitoring the effects of anti-inflammatory or antioxidant drugs on cartilage degradation. (c) 2004 OsteoArthritis Research Society International. Published by Elsevier Ltd. All rights reserved. [less ▲]

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See detailNew service development in high tech sectors: A decision making perspective
Van Riel, Allard ULg; Lievens, Annouk

in International Journal of Service Industry Management (2004), 15(1), 72-101

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See detailA New Shift-Share Method
Artige, Lionel ULg; Van Neuss, Leif ULg

in Growth and Change (2014), 45(4), 667-683

Shift-share analysis is a decomposition technique widely used in regional studies to quantify an industry-mix effect and a competitive effect on the growth of regional employment (or any other relevant ... [more ▼]

Shift-share analysis is a decomposition technique widely used in regional studies to quantify an industry-mix effect and a competitive effect on the growth of regional employment (or any other relevant variable) relative to the national average. This technique has always been subject to criticism for its lack of theoretical basis. This paper presents a critical assessment of the methods suggested by Dunn (1960) and by Esteban-Marquillas (1972) and proposes a new shift-share method, which separates out the two effects unambiguously. By way of illustration, we provide an application to manufacturing employment in the Belgian provinces between 1995 and 2007. [less ▲]

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See detailA New Shift-Share Method
Artige, Lionel ULg; Van Neuss, Leif ULg

E-print/Working paper (2012)

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See detailNew silica based polymeric systems designed for the solid-liquid extraction of uranyl ions
Caprasse, F.; Leroy, Delphine ULg; Martinot, Lucien et al

in Journal of Materials Chemistry (2002), 12(1), 137-142

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See detailNew silicone based antifoam for fermentation
Etoc, Ariane; Delvigne, Frank ULg; Lecomte, Jean-Paul et al

Conference (2006, April 30)

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See detailA NEW SIMPLIFIED ANALYTICAL DESIGN METHOD FOR STEEL AND COMPOSITE SWAY FRAMES
Demonceau, Jean-François ULg; Jaspart, Jean-Pierre ULg

in Journal of Constructional Steel Research (2013)

Eurocode 4 is the European design code for composite construction; in its so-called EN 1994-1-1 version, the design of “non-sway buildings” is mainly covered. As a result, EC4 focuses on the check of ... [more ▼]

Eurocode 4 is the European design code for composite construction; in its so-called EN 1994-1-1 version, the design of “non-sway buildings” is mainly covered. As a result, EC4 focuses on the check of structural elements like beams, columns, slabs and joints. However, in the last years, the construction of taller buildings and larger industrial halls without wind bracing systems tends to make global instability a relevant failure mode, which is not well covered by Eurocode 4. Recently, intensive experimental, numerical and theoretical investigations have been carried out at Liège University. The latter aimed at improving the knowledge in the field of sway composite building frames and at developing appropriate design rules. The rotational behavior of the beam-to-column composite joints is one of the key aspects of the problem to which a special attention has been paid. This paper reflects investigations carried out at Liège University on this topic. In particular, an innovative simplified analytical method to predict the ultimate loading factor and the associated collapse mode of both steel and composite frames subjected to static loadings is presented. [less ▲]

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See detailNew simplified analytical method for the prediction of global stability of composite sway frames
Ly, Dong Phuong Lam ULg; Demonceau, Jean-François ULg; Jaspart, Jean-Pierre ULg

in EUROSTEEL 2008, 5th European Conference on Steel and Composite Structures (2008, September)

In the last years, the construction of taller composite buildings and larger composite industrial halls without wind bracing systems is susceptible to make global instability a relevant failure mode. This ... [more ▼]

In the last years, the construction of taller composite buildings and larger composite industrial halls without wind bracing systems is susceptible to make global instability a relevant failure mode. This one is not yet covered by EC4 [2]. This paper reflects investigations carried out of Liege University on this topic. In particular, an innovative simplified analytical method to predict the ultimate loading factor and the associated collapse mode of composite frames is derived. [less ▲]

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See detailNew simplified analytical method for the Prediction of global stability of steel and composite sway frames
Demonceau, Jean-François ULg; Ly, Dong Phuong Lam ULg; Coméliau, Ludivine ULg et al

in Proceedings of the annaual stability conference, 2010 (2010, May)

Eurocode 4 is the European design code for composite construction; in its so-called EN 1994-1-1 version, the design of “non-sway buildings” is mainly covered. As a result, EC4 focuses on the check of ... [more ▼]

Eurocode 4 is the European design code for composite construction; in its so-called EN 1994-1-1 version, the design of “non-sway buildings” is mainly covered. As a result, EC4 focuses on the check of structural elements like beams, columns, slabs and joints. However, in the last years, the construction of taller buildings and larger industrial halls without wind bracing systems tends to make global instability a relevant failure mode, which is not well covered by Eurocode 4. Recently, intensive experimental, numerical and theoretical investigations have been carried out at Liège University. The latter aimed at improving the knowledge in the field of sway composite building frames and at developing appropriate design rules. The rotational behavior of the beam-to-column composite joints is one of the key aspects of the problem to which a special attention has been paid. This paper reflects investigations carried out at Liege University on this topic. In particular, an innovative simplified analytical method to predict the ultimate loading factor and the associated collapse mode of both steel and composite frames subjected to static loadings is presented. [less ▲]

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See detailNew simulation tools usable in the energy audit of HVAC systems
Lebrun, Jean ULg; Bertagnolio, Stéphane ULg

Scientific conference (2008, October)

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See detailA new single well tracer test: the Finite Volume Point Dilution Method. Theory, field application and model validation
Brouyère, Serge ULg; Batlle Aguilar, Jordi ULg; Goderniaux, Pascal ULg et al

in Calibration and Reliability in Groundwater Modelling: Credibility in Modelling (Pre-Published Proc. of ModelCARE’2007) (2007)

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See detailThe new solar abundances - Part II: the crisis and possible solutions
Montalban Iglesias, Josefa ULg; Miglio, Andrea ULg; Theado, S. et al

in Communications in Asteroseismology (2006), 147

Recent 3D, NLTE analysis of the solar spectrum (Asplund et al. 2006, Part I; Asplund et al. 2005) have led to a significant reduction of the CNO and Ne abundances leading to a (Z/X) 30% smaller than the ... [more ▼]

Recent 3D, NLTE analysis of the solar spectrum (Asplund et al. 2006, Part I; Asplund et al. 2005) have led to a significant reduction of the CNO and Ne abundances leading to a (Z/X) 30% smaller than the previously recommended value. The corresponding decrease in opacity increases dramatically the discrepancies between the sound-speed derived from helioseismology and our new standard solar models (SSM). We present in this paper some numerical experiments trying to reduce this discrepancy. [less ▲]

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See detailNew Solid-Shell Finite Element Based on EAS and ANS Concepts for Sheet Metal Forming
Ben Bettaieb, Amine ULg; Duchene, Laurent ULg; Zhang, Lihong ULg et al

in AIP Conference Proceedings (2011), 1383

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See detailA New solution to the Dyson-Schwinger equation for the gluon propagator
Cudell, Jean-René ULg

in Nucl. Phys. Proc. Suppl. (1992), 25B

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See detailNew Solutions to the Problem of Range Dependence in Bistatic STAP Radars
Lapierre, Fabian; Van Droogenbroeck, Marc ULg; Verly, Jacques ULg

in IEEE Radar Conference 2003, Proceedings (2003, May)

We address the problem of detecting slow-moving <br />targets using a space-time adaptive processing (STAP) radar. <br />The construction of optimum weights at each range implies <br />the estimation of ... [more ▼]

We address the problem of detecting slow-moving <br />targets using a space-time adaptive processing (STAP) radar. <br />The construction of optimum weights at each range implies <br />the estimation of the clutter covariance matrix. This is typically <br />done by straight averaging of neighboring data snapshots. <br />However, in bistatic configurations, these snapshots are rangedependent. <br />As a result, straight averaging results in poor performance. <br />After reviewing existing methods for handling the <br />range-dependence, we present new methods exploiting the precise <br />shape of the bistatic direction-Doppler curves. [less ▲]

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See detailA new spatial thin-walled beam finite element for tapered members
Boissonnade, N.; Degée, Hervé ULg

in Proceedings of the National Conference on Theoretical and Applied Mechanics (2006)

This paper presents the essentials of an original geometrically and materially non-linear 3-D tapered beam finite element. The theoretical bases of the element are described, with particular attention ... [more ▼]

This paper presents the essentials of an original geometrically and materially non-linear 3-D tapered beam finite element. The theoretical bases of the element are described, with particular attention paid to the choice of an appropriate displacement field and to the corresponding non-linear axial strains. Specific numerical problems met in the development of the finite element are examined, concerning mainly shear and membrane locking and the handling of rigid body motions. Worked examples on isolated members are presented for various types of analyses: elastic linear, elastic critical and geometrically and materially non-linear analyses. Good accuracy with reference to numerical results is shown, as well as good convergence properties. It is also demonstrated – analytically and numerically – that the use of prismatic beam finite elements for the analysis of tapered beams (segmentation technique) may lead to significant discrepancies when the behaviour is influenced by torsional aspects. [less ▲]

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See detailA new species of Caprella (Crustacea: Amphipoda) from the Mediterranean Sea
Sturaro, Nicolas ULg; Guerra-García, José Manuel

in Helgoland Marine Research (2012)

A new caprellid amphipod, Caprella tavolarensis n. sp., is described based on specimens collected from a Posidonia oceanica seagrass meadow at the Tavolara- Punta Coda Cavallo Marine Protected Area ... [more ▼]

A new caprellid amphipod, Caprella tavolarensis n. sp., is described based on specimens collected from a Posidonia oceanica seagrass meadow at the Tavolara- Punta Coda Cavallo Marine Protected Area (Sardinia, Mediterranean Sea). The species is close to Caprella liparotensis, but can be clearly distinguished by smaller size, presence of a short rostrum, body elongate and dorsally smooth, absence of serrate carina on the basis of gnathopod 2 and pereopods, mouthparts scarcely setose, absence of Wne setae on peduncle of antenna 1 and absence of swimming setae on antenna 2. The number of caprellid species reported from the Mediterranean Sea has increased from 23 (1993) to 41 (2010), consequently, further taxonomical studies should be addressed to properly estimate the total amphipod diversity in the Mediterranean Sea. [less ▲]

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