Role des somatomedines/insulin-like growth factors dans la croissance ponderale foetale.

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(3),

Le rôle des universités

Speech (1913)

Le rôle des villes dans l’encadrement et la planification stratégique du développement économique des quartiers urbains

Conference (2010, February 09)

Le role des virus dans la pathogenie du diabete de type 1

in Revue Médicale de Liège (2005), 60(5-6, May-Jun), 297-302

The precise role of viral infections in the pathogenesis of type 1 diabetes is still the subject of an important discussion. Coxsackievirus B4 (CVB4) is the virus the most implicated by a series of ... [more ▼]

The precise role of viral infections in the pathogenesis of type 1 diabetes is still the subject of an important discussion. Coxsackievirus B4 (CVB4) is the virus the most implicated by a series of epidemiological studies. Pathogenic mechanisms underlying such a relationship implicate a molecular mimicry between CVB4 sequences and beta-cell autoantigens, but mainly a persistent CVB4 infection of pancreatic beta cells followed by a release of sequestered beta antigens and a "bystander" activation of autoreactive T cells. The demonstration of intrathymic expression of antigens specific of peripheral tissues has opened a novel research perspective. We have shown that CVB4 is able to infect in a persistent and producive manner human thymic epithelial cell cultures and human fetal thymic lobes in organotypic cultures. This infection induces an important thymic dysfunction characterized by a severe depletion of thymocytes (thymic T cells) and an up-regulated expression by thymic epithelial and T cells of class I proteins encoded by the major histocompatibility complex (MHC-I). Such thymic dysfunction might be responsible for a decrease of beta-cell central self-tolerance and anti-CVB4 cytotoxic CD8 T-cell activity. CVB4-induced thymic dysfunction would contribute in close association with the peripheral "bystander" effect to the destruction of insulin-secreting islet beta cells and to the development of type 1 diabetes. [less ▲]

Le rôle des zones urbaines sur le développement (Note rédigée dans le cadre de l'opération de réflexion collective du PS)

Report (2013)

Le rôle du clergé dans la construction d'un discours d'autorité sur la langue en milieu francophone minoritaire: l'exemple de l'Acadie du Nouveau-­Brunswick à la fin du 19e siècle

Conference (2012, June 14)

Le rôle du coordinateur qualité dans le laboratoires de Biologie clinique

Conference (2001, October 25)

Le rôle du foie dans l'homéostasie glucidique: une relecture des travaux de Claude Bernard

in Journées Annuelles de Diabetologie de l'Hôtel-Dieu (1995)

Rôle du gène cap-like dans la répression catabolique chez Streptomyces

Conference (2002)

Le rôle du lien social dans le parcours des SDF : enseignements pour une politique publique

Conference (2006, September)

The theory of social capital according to Putnam insists on the fact that social relations are useful recourses in different situations of life. But it does not fit acuretaly the description of the ... [more ▼]

The theory of social capital according to Putnam insists on the fact that social relations are useful recourses in different situations of life. But it does not fit acuretaly the description of the situation of homeless people who are not necessarily deprived of a social network but who become more demanding in their social relationships. They want to give and receive and not only to use people as recourses. A Maussian theory of social link through gift is probably more relevant than social capital theory to describe those phenomena. [less ▲]