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See detailORIGIN AND EVOLUTION OF THE NORTHERN HEMISPHERE DISJUNCTION IN THE MOSS GENUS HOMALOTHECIUM (BRACHYTHECIACEAE)
Huttunen, Sanna; Hedenäs, Lars; Ignatov, Misha et al

in American Journal of Botany (2008)

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See detailOrigin and fate of the single island endemic moss Orthotrichum handiense
Patino Llorente, Jairo ULg; Medina, R; Vanderpoorten, Alain ULg et al

in Journal of Biogeography (2013), 40

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See detailOrigin and immunoescape of uterine cervical cancer
Van hede, Dorien ULg; Langers, Inge ULg; DELVENNE, Philippe ULg et al

in Presse Médicale (in press)

Human papillomavirus associated uterine cervical cancer is an important public health problem since it is classified as the fourth most common cancer in women worldwide with more than 500 000 recorded ... [more ▼]

Human papillomavirus associated uterine cervical cancer is an important public health problem since it is classified as the fourth most common cancer in women worldwide with more than 500 000 recorded cases. This review is focused on where and why HPV infection induces cervical cancers and how this virus avoids the host immune response. Immunological therapeutic approaches are also addressed. [less ▲]

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See detailOrigin and properties of the two-dimensional electron gas at the LaAlO3/SrTiO3 interface: a first-principles hybrid functional study.
Fontaine, Denis ULg

Doctoral thesis (2014)

Complex oxides exhibit a wide range of physical properties making them very attractive for future electronic and device applications. Although more and more studied, additional scientific investigations ... [more ▼]

Complex oxides exhibit a wide range of physical properties making them very attractive for future electronic and device applications. Although more and more studied, additional scientific investigations are required, especially in oxide interfaces, where new and amazing phenomena can arise. A prototypical example is the LaAlO3-SrTiO3 interface that appear to be conducting, magnetic or even supra-conducting while these properties are not present in the LaAlO3 and SrTiO3 bulk insulator compounds. The conductivity arises from the formation of a highly localized electron gas at the interface which exhibits a different behavior than the one at semiconductor interfaces. Even nowadays, its exact origin, intrinsic versus extrinsic, is still intensively debated. The existence of an electric field in LaAlO3 used as a key feature of models based on an intrinsic origin is highly controversial. In these models, the closing of the band gap with increasing LaAlO3 film thicknesses finally results to a Zener breakdown and to the metal/insulator transition. In this Ph.D. thesis we aim to investigate the various consequences of the presence of an electric field in LaAlO3 through first-principles calculations in pristine LaAlO3-SrTiO3 interfaces. First, using both experimental and theoretical structural distortions in LaAlO3, we predicted a lattice expansion via an electrostrictive effect, supporting the existence of an electric field in LaAlO3. Second, the metal/insulator transition was tuned with regards to the intensity of the electric field in the film, which was controlled by the composition of a solid solution between LaAlO3 and SrTiO3. The theoretical results match the experimental one where, nevertheless, extrinsic origin mechanisms are allowed and defects are present. These two works are in favors of an intrinsic origin of the electronic gas observed in LaAlO3-SrTiO3 heterostructures. In addition, a relationship between the sheet carrier density and spatial extension of the gas was established and thus setting an intrinsic threshold to the sheet carrier concentration. At lower density the electrons are strictly localized close to the interface while above this value the carriers start to spill into the SrTiO3 substrate. [less ▲]

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See detailOrigin and Pulsation of Hot Subdwarfs
Randall, Suzanna K; Fontaine, Gilles; Charpinet, Stéphane et al

in Proceedings of the International Astronomical Union (2014, February), 301

We briefly introduce hot subdwarfs and their evolutionary status before discussing the different types of known pulsators in more detail. Currently, at least six apparently distinct types of variable are ... [more ▼]

We briefly introduce hot subdwarfs and their evolutionary status before discussing the different types of known pulsators in more detail. Currently, at least six apparently distinct types of variable are known among hot subdwarfs, encompassing p- as well as g-mode pulsators and objects in the Galactic field as well as in globular clusters. Most of the oscillations detected can be explained in terms of an iron opacity mechanism, and quantitative asteroseismology has been very successful for some of the pulsators. In addition to helping constrain possible evolutionary scenarios, studies focussing on stellar pulsations have also been used to infer planets and characterize the rotation of the host star. [less ▲]

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See detailOrigin and putative colonization routes for invasive rodent taxa in the democratic Republic of Congo
Kaleme, P. K.; Bates, J. M.; Belesi, H. K. et al

in African Zoology (2011), 46(1), 133-145

The threat posed by biological invasions is well established. An important consideration in preventing the spread of invasives and also subsequent introductions lies in understanding introduction pathways ... [more ▼]

The threat posed by biological invasions is well established. An important consideration in preventing the spread of invasives and also subsequent introductions lies in understanding introduction pathways. The Democratic Republic of the Congo (DRC) houses a large percentage of the world's biodiversity, yet no national strategy exists to deal with the growing number of invasive alien species. Amongst these are the house mouse and ship and Norwegian rats. By comparing our result to published data, we show that species were possibly introduced into the DRC via two routes. The first is via the western seaport at Kinshasa where specimens of M. m. domesticus and R. rattus on the western and northwestern side of the DRC show ties with European haplotypes. The second is via the east where specimens of R. rattus appear linked to Arab and southeast Asian haplotypes. Future work should consider more comprehensive sampling throughout the DRC to more accurately investigate the occurrence of invasive species throughout the country as well as extend sampling to other African countries. [less ▲]

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See detailOrigin and radiation of the earliest vascular land plants
Steemans, Philippe ULg; Le Herisse, A.; Melvin, J. et al

in Science (2009), 324

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See detailThe origin of Annex IV of the Regulation 428/2009
Michel, Quentin ULg

Conference (2011, May 04)

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See detailThe origin of catecholaminergic inputs to the song control nucleus RA in canaries
Appeltants, D.; Ball, G. F.; Balthazart, Jacques ULg

in Neuroreport (2002), 13(5), 649-653

Song control nuclei in oscines receive dense catecholaminergic inputs but their anatomical origin is poorly understood. We analyzed catecholaminergic inputs to the nucleus robustus archistriatalis (RA) in ... [more ▼]

Song control nuclei in oscines receive dense catecholaminergic inputs but their anatomical origin is poorly understood. We analyzed catecholaminergic inputs to the nucleus robustus archistriatalis (RA) in canaries by retrograde tract-tracing combined with immunocytochemistry for tyrosine hydroxylase. In both sexes, dopaminergic inputs to RA come mostly from the A1 1 (mesencephalic central gray) and A10 (area ventralis of Tsai) cell groups but the locus coeruleus and subcoeruleus (A6) also send noradrenergic projections to RA. No input originates in the hypothalamic and in the A5 to A1 catecholaminergic groups. These findings and previous work on the high vocal center (HVc) indicate that the two major nuclei of the motor pathway controlling song production (RA and HVc) receive catecholaminergic inputs of similar origins. [less ▲]

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See detailOrigin of Proterozoic anorthosites by fusion of the lower crust
Longhi, John; Vander Auwera, Jacqueline ULg; Fram, Miranda

in Eos (1996, November), 77(46), 760

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See detailOrigin of radial glial cells in cerebral mouse cortex: A study using combined immunohistochemical and 3H thymidine labeling
Misson, Jean-Paul ULg; Edwards, M. A.; Yamamoto, M. et al

in Neuroscience Research. Supplement : The Official Journal of the Japan Neuroscience Society (1986)

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See detailOrigin of reversed vortex ratchet motion
Gillijns, W.; Silhanek, Alejandro ULg; Moshchalkov, V. V. et al

in Physical Review Letters (2007), 99(24),

We experimentally demonstrate that the origin of multiply reversed rectified vortex motion in an asymmetric pinning landscape not only is a consequence of the vortex-vortex interactions but also ... [more ▼]

We experimentally demonstrate that the origin of multiply reversed rectified vortex motion in an asymmetric pinning landscape not only is a consequence of the vortex-vortex interactions but also essentially depends on the ratio between the characteristic interaction distance and the period of the asymmetric pinning potential. We study four samples with different periods d of the asymmetric potential. For large d the dc voltage V(dc) recorded under a ac excitation indicates that the average vortex drift is from bigger to smaller dots for all explored positive fields. As d is reduced, a series of sign reversals in the dc response are observed as a function of field. We show that the number of sign reversals increases as d decreases. These findings are in agreement with recent computer simulations and illustrate the relevance of the different characteristic lengths for the vortex rectification effects. [less ▲]

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See detailOrigin of Saturn's aurora: Simultaneous observations by Cassini and the Hubble Space Telescope
Bunce, E. J.; Arridge, C. S.; Clarke, J. T. et al

in Journal of Geophysical Research (2008), 113(A9),

Outer planet auroras have been imaged for more than a decade, yet understanding their physical origin requires simultaneous remote and in situ observations. The first such measurements at Saturn were ... [more ▼]

Outer planet auroras have been imaged for more than a decade, yet understanding their physical origin requires simultaneous remote and in situ observations. The first such measurements at Saturn were obtained in January 2007, when the Hubble Space Telescope imaged the ultraviolet aurora, while the Cassini spacecraft crossed field lines connected to the auroral oval in the high-latitude magnetosphere near noon. The Cassini data indicate that the noon aurora lies in the boundary between open- and closed-field lines, where a layer of upward-directed field-aligned current flows whose density requires downward acceleration of magnetospheric electrons sufficient to produce the aurora. These observations indicate that the quasi-continuous main oval is produced by the magnetosphere-solar wind interaction through the shear in rotational flow across the open-closed-field line boundary. [less ▲]

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See detailThe origin of the alpha-domain intermediate in the folding of hen lysozyme
Matagne, André ULg; Chung, E. W.; Ball, L. J. et al

in Journal of Molecular Biology (1998), 277(5), 997-1005

Stopped-flow fluorescence and circular dichroism spectroscopy have been used in conjunction with quenched-flow hydrogen exchange labelling, monitored by electrospray ionization mass spectrometry, to ... [more ▼]

Stopped-flow fluorescence and circular dichroism spectroscopy have been used in conjunction with quenched-flow hydrogen exchange labelling, monitored by electrospray ionization mass spectrometry, to compare the refolding kinetics of hen egg-white lysozyme at 20 degrees C and 50 degrees C. At 50 degrees C there is clear evidence for distinct fast and slow refolding populations, as observed at 20 degrees C, although folding occurs significantly more rapidly. The folding process is, however, substantially more cooperative at the higher temperature. In particular, the transient intermediate on the major refolding pathway at 20 degrees C, having persistent native-like structure in the alpha-helical domain of the protein, is not detected by hydrogen exchange labelling at 50 degrees C. Ln addition, the characteristic maximum in negative ellipticity and the minimum in fluorescence intensity observed in far UV CD and intrinsic fluorescence experiments at 20 degrees C, respectively, are not seen at 50 degrees C. Addition of 2 M NaCl to the refolding buffer at 50 degrees C, however, regenerates both the hydrogen exchange and optical properties associated with the alpha-domain intermediate but has no significant effect on the overall refolding kinetics. Together with previous findings, these results indicate that non-native interactions within the alpha-domain intermediate are directly responsible for the unusual optical properties observed during refolding, and that this intermediate accumulates as a consequence of its intrinsic stability in a folding process where the formation of stable structure in the beta-domain constitutes the rate-limiting step for the majority of molecules. (C) 1998 Academic Press Limited. [less ▲]

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See detailThe origin of the forests in the North of the Congo Republic: an anthraco-pedological contribution.
Gillet, Jean-François; Beeckman, H.; Doucet, Jean-Louis ULg

in Damblon, F.; Court-Picon, M. (Eds.) Geological survey of Belgium professional papers N. 303-2008/1 (2008)

The vegetation of the Sangha region in the North of the Congo Republic is composed of a mosaic of forest formations including semi-deciduous humid dense forests characterized by Ulmaceae and Sterculiaceae ... [more ▼]

The vegetation of the Sangha region in the North of the Congo Republic is composed of a mosaic of forest formations including semi-deciduous humid dense forests characterized by Ulmaceae and Sterculiaceae, evergreen forests with Gilbertiodendron dewevrei and woodland with Marantaceae. Palynological analyses proved that this region witnessed an arid phase 2500 years ago. This was associated with an important reduction of the forest cover and an equal extension of savannahs that could have facilitated the migrations of the Bantou people and the propagation of the shifting cultivation agriculture in the whole region which is, still at the moment, sparsely populated. In order to verify climatic and anthropological influences on the present composition of the forest vegetation, a pedological investigation has been set up in the region of Pokola (1.5° N; 16.5 °E) comprising 43 drillings and 12 pits along a gradient covering the different forest types. Charcoal has been found in 84% of the cores in all the forest formations especially between 30 cm and 60 cm depth. Charred oil palm seeds (Elaeis guineensis), often a culture accompanying species, have been found in 60% of the pits. C14 analysis revealed dates between 600 and 2200 years BP. Pedological analyses showed the association between semi-deciduous humid dense forest and red ferralsols, between Marantaceae woodlands and ochre ferralsols (poorer than the former) and between Gilbertiodendron dewevrei stands and pseudogleys and gleysols. The identification of the botanical taxon of charcoal fragments from tropical regions deals with important limitations due to scarce reference collections that are far from being complete. Therefore it is crucial to combine a thorough knowledge of the different vegetation types and their character species with a wood anatomical study. Given the hypothesised strong influence of man induced perturbations and past climatic changes, these results emphasize the importance of edaphic factors in differentiating the forest stands in the North of the Congo Republic. They also permit a better understanding of a potential evolution of the forests in this region driven by the actual climatic changes. [less ▲]

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