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See detailPatching Asymptotics Solution of a Cable with a Small Bending Stiffness
Denoël, Vincent ULg; Canor, Thomas ULg

in Journal of Structural Engineering (2013), 139

The analysis of a cable with a small bending stiffness is a problem encountered in many engineering applications such as the fatigue assessment of stay cables, the modeling of pipeline laying operation or ... [more ▼]

The analysis of a cable with a small bending stiffness is a problem encountered in many engineering applications such as the fatigue assessment of stay cables, the modeling of pipeline laying operation or the determination of bending stresses in drillpipe assemblies. Because this phenomenon is modeled by a singularly perturbed equation, standard numerical techniques fail to solve these problems efficiently. As an alternative, provided the complexity of the analytical developments does not preclude their application, these problems may be tackled with appealing analytical procedures such as matching asymptotics or multiple scales. Otherwise advanced numerical simulations combining patching asymptotics within a numerical framework are the only possible approach for problems where the governing equations are too complex. Patching asymptotics also features a number of merits such as the possibility of using a boundary layer with a finite extent. Aiming at a better understanding of this latter technique, it is considered here to determine the solution of a cable with a small bending stiffness. Interesting details about patchability conditions and about how to restore higher derivatives continuity are included. The accuracy of the patching asymptotics approach is also compared with that of matched asymptotics. [less ▲]

Detailed reference viewed: 56 (13 ULg)
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See detailPatent foramen ovale and Migraine
Schwedt, TJ; Schoenen, Jean ULg

in Schoenen, Jean; Dodick, DW; Sándor, P (Eds.) Comorbidity in Migraine (2011)

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See detailPatenting activity in manufacturing organoclays for nanocomposite applications
Naveau, Elodie ULg; Detrembleur, Christophe ULg; Jérôme, Christine ULg et al

in Recent Patents on Materials Science (2009), 2(1), 43-49

For the last two decades, intensive research has been focused on developing reinforced polymers with incorporation of nanometric fillers. Amongst the different types of nanofillers, those based on layered ... [more ▼]

For the last two decades, intensive research has been focused on developing reinforced polymers with incorporation of nanometric fillers. Amongst the different types of nanofillers, those based on layered silicates (commonly known as clays), have been most widely investigated. Dispersing clay sheets on a nanoscopic scale (so-called exfoliation) indeed allows materials with enhanced thermal, mechanical, rheological, flame retardancy and barrier properties to be produced. However, the nanocomposite performances are strongly dependent upon the extent of clay exfoliation. In order to enhance the compatibility between the pristine clay, hydrophilic, and the polymer, hydrophobic, and to achieve a good delamination of the nanolayers, an organo-modification of the clay is most usually necessary. This mini-review will provide an outline of patenting activity in the field of manufacturing organoclays through ionic exchange. The variety of organic modifiers and the diverse processing techniques will be detailed, aiming to extract the most relevant organoclays for successful nanocomposite formation at industrial scale. [less ▲]

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See detailPaternal history of asthma and airway responsiveness in children with asthma
Raby, B. A.; Van Steen, Kristel ULg; Celedon, J. C. et al

in American Journal of Respiratory & Critical Care Medicine (2005), 172(5), 552-8

RATIONALE: Little is known regarding the relationship between parental history of asthma and subsequent airway hyperresponsiveness (AHR) in children with asthma. OBJECTIVES: We evaluated this relationship ... [more ▼]

RATIONALE: Little is known regarding the relationship between parental history of asthma and subsequent airway hyperresponsiveness (AHR) in children with asthma. OBJECTIVES: We evaluated this relationship in 1,041 children with asthma participating in a randomized trial of antiinflammatory medications (the Childhood Asthma Management Program [CAMP]). METHODS: Methacholine challenge testing was performed before treatment randomization and once per year over an average of 4.5 years postrandomization. Cross-sectional and longitudinal repeated measures analyses were performed to model the relationship between PC20 (the methacholine concentration causing a 20% fall in FEV1) with maternal, paternal, and joint parental histories of asthma. Models were adjusted for potential confounders. MEASUREMENTS AND MAIN RESULTS: At baseline, AHR was strongly associated with a paternal history of asthma. Children with a paternal history of asthma demonstrated significantly greater AHR than those without such history (median log(e)PC20, 0.84 vs. 1.13; p = 0.006). Although maternal history of asthma was not associated with AHR, children with two parents with asthma had greater AHR than those with no parents with asthma (median log(e)PC20, 0.52 vs. 1.17; p = 0.0008). Longitudinal multivariate analysis of the relation between paternal history of asthma and AHR using repeated PC20 measurements over 44 months postrandomization confirmed a significant association between paternal history of asthma and AHR among children in CAMP. CONCLUSIONS: Our findings suggest that the genetic contribution of the father is associated with AHR, an important determinant of disease severity among children with asthma. [less ▲]

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See detailLe paternalisme en question. Les anciens ouvriers de la Gécamines face à la libéralisation du secteur minier katangais (RD Congo)
Rubbers, Benjamin ULg

Book published by L'Harmattan, collection 'Cahiers africains' (2013)

En 1926, l’Union minière du Haut-Katanga jette les bases de sa politique paternaliste, qui touchera tous les aspects de la vie quotidienne de ses travailleurs pendant plus d’un demi-siècle. En 2003, après ... [more ▼]

En 1926, l’Union minière du Haut-Katanga jette les bases de sa politique paternaliste, qui touchera tous les aspects de la vie quotidienne de ses travailleurs pendant plus d’un demi-siècle. En 2003, après une décennie dans la tourmente, 10 000 agents sont licenciés de l’entreprise dans le cadre du projet de libéralisation du secteur minier conçue par la Banque mondiale. De quelle façon ont-ils réagi à leur ‘abandon’ par l’entreprise ? Comment ont-ils fait face à leur nouvelle indépendance ? Quels effets le déclin de leurs conditions de vie, puis leur départ de la société, ont-ils induits sur leurs rapports avec leur épouse, leurs enfants, leur entourage ? Basé sur une recherche ethnographique dans un camp ouvrier de Likasi (Katanga, République Démocratique du Congo), ce livre s’attache à répondre à ces questions en prenant appui sur un cadre d’analyse inspiré de M. Foucault. Cette approche lui permet de développer au fil des pages une réflexion plus large sur l’expérience vécue du paternalisme dans le nouvel ordre économique que la Banque mondiale cherche à imposer dans cette région de l’Afrique. [less ▲]

Detailed reference viewed: 49 (13 ULg)
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See detailPaternity analyses reveal the variable efficacy of 4 males in a Barbus polyandrous cross.
Chenuil, A.; Binda, O.; Poncin, Pascal ULg et al

Poster (1997)

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See detailPath Similarity Evaluation using Bloom Filters
Donnet, Benoît ULg; Gueye, Bamba,; Kaafar, Mohamed Ali

in Computer Networks (2012), 56(2), 858-869

The performance of several Internet applications often relies on the measurability of path similarity between different participants. In particular, the performance of content distribution networks mainly ... [more ▼]

The performance of several Internet applications often relies on the measurability of path similarity between different participants. In particular, the performance of content distribution networks mainly relies on the awareness of content sources topology information. It is commonly admitted nowadays that, in order to ensure either path redundancy or efficient content replication, topological similarities between sources is evaluated by exchanging raw traceroute data, and by a hop by hop comparison of the IP topology observed from the sources to the several hundred or thousands of destinations. In this paper, based on real data we collected, we advocate that path similarity comparisons between different Internet entities can be much simplified using lossy coding techniques, such as Bloom filters, to exchange compressed topology information. The technique we introduce to evaluate path similarity enforces both scalability and data confidentiality while maintaining a high level of accuracy. In addition, we demonstrate that our technique is scalable as it requires a small amount of active probing and is not targets dependent. [less ▲]

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See detailPathbase: a database of mutant mouse pathology
Schofield, P. N.; Bard, J. B. L.; Booth, C. et al

in Nucleic Acids Research (2004), 32(Sp. Iss. SI), 512-515

Pathbase is a database that stores images of the abnormal histology associated with spontaneous and induced mutations of both embryonic and adult mice including those produced by transgenesis, targeted ... [more ▼]

Pathbase is a database that stores images of the abnormal histology associated with spontaneous and induced mutations of both embryonic and adult mice including those produced by transgenesis, targeted multagenesis and chemical mutagenesis. Images of normal mouse histology and strain-dependent background lesions are also available. The database and the images are publicly accessible (http://www.pathbase.net) and linked by anatomical site, gene and other identifiers to relevant databases; there are also facilities for public comment and record annotation. The database is structured around a novel ontology of mouse disorders (MPATH) and provides high-resolution downloadable images of normal and diseased tissues that are searchable through orthogonal ontologies for pathology, developmental stage, anatomy and gene attributes (GO terms), together with controlled vocabularies for type of genetic manipulation or mutation, genotype and free text annotation for mouse strain and additional attributes. The database is actively curated and data records assessed by pathologists in the Pathbase Consortium before publication. The database interface is designed to have optimal browser and platform compatibility and to interact directly with other web-based mouse genetic resources. [less ▲]

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See detailPathbase: A new reference resource and database for laboratory mouse pathology
Schofield, P. N.; Bard, J. B. L.; Boniver, Jacques ULg et al

in Radiation Protection Dosimetry (2004), 112(4 Sp. Iss. SI), 525-528

Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of ... [more ▼]

Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology. [less ▲]

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See detailPathogenèse de l'endométriose
Nisolle, Michelle ULg; Alvarez Gonzalez, Maria-Luz ULg; Colombo, M. et al

in Gynécologie Obstétrique & Fertilité (2007), 35(9), 898-903

Endometriosis, defined by the development of endometrial tissue outside the uterus, is a benign disease responsible for infertility and pelvic pain. The diagnosis based on a detailed gynecological history ... [more ▼]

Endometriosis, defined by the development of endometrial tissue outside the uterus, is a benign disease responsible for infertility and pelvic pain. The diagnosis based on a detailed gynecological history and a careful clinical examination should be done as early as possible in order to treat patients correctly. Medical treatment is not appropriate in all cases and surgical treatment should be proposed but morbidity is related to the severity of the lesion. Ectopic implantation of endometrial cells needs complex interactions between host tissue and epithelial endometrial cells. The conditions for the development of endometriosis are estrogeno-dependent growth of endometrial cells, induction of angiogenesis and lymphangiogenesis. Principal cellular and molecular factors of angiogenesis, lymphangiogenesis and fibrosis should be identified in order to develop new therapeutic strategies of endometriosis. [less ▲]

Detailed reference viewed: 128 (14 ULg)
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See detailPathogenesis and management of acute pulmonary embolism
D'Orio, Vincenzo ULg; MENDES, P; SAAD, G et al

in Acta Clinica Belgica (1989), 44

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See detailPathogenesis of abdominal aortic aneurysm (AAA) formation.
Limet, Raymond ULg; Richelle, Betty ULg; VERLOES, Alain ULg et al

in Acta Chirurgica Belgica (1998), 98(5), 195-8

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See detailPathogenesis of dermatophytosis
Vermout, Sandy; Tabart, Jeremy; Baldo, Aline ULg et al

in Mycopathologia (2008), 166(5-6), 267-275

Despite the superficial localization of most dermatophytosis, host-fungus relationship in these infections is complex and still poorly elucidated. Though many efforts have been accomplished to ... [more ▼]

Despite the superficial localization of most dermatophytosis, host-fungus relationship in these infections is complex and still poorly elucidated. Though many efforts have been accomplished to characterize secreted dermatophytic proteases at the molecular level, only punctual insights have been afforded into other aspects of the pathogenesis of dermatophytosis, such as fungal adhesion, regulation of gene expression during the infection process, and immunomodulation by fungal factors. However, new genetic tools were recently developed, allowing a more rapid and high-throughput functional investigation of dermatophyte genes and the identification of new putative virulence factors. In addition, sophisticated in vitro infection models are now used and will open the way to a more comprehensive view of the interactions between these fungi and host epidermal cells, especially keratinocytes. [less ▲]

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See detailPathogenesis of migraine: the biobehavioural and hypoxia theories reconciled.
Schoenen, Jean ULg

in Acta Neurologica Belgica (1994), 94(2), 79-86

The recent pathophysiological data obtained in migraine patients during and between attacks are reviewed in this article. They suggest that the headache in migraine is due to activation of the trigemino ... [more ▼]

The recent pathophysiological data obtained in migraine patients during and between attacks are reviewed in this article. They suggest that the headache in migraine is due to activation of the trigemino-vascular system. While this can be found in other headache disorders, the process leading ultimately to trigemino-vascular activation appears to characterize migraine. Between attacks, the migrainous brain has two functional abnormalities: a habituation defect in sensory processing, probably related to dysfunctioning transmitter (serotonin, noradrenaline) systems and a reduced mitochondrial energy reserve. Both abnormalities may be genetically determined and concur to favour biochemical shifts leading to the migraine attack as a primary protective mechanism of the brain. Such a model of migraine pathogenesis reconciles the biobehavioural and hypoxia theories and opens new therapeutic perspectives. [less ▲]

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See detailPathogenesis, latency and reactivation of infections by herpesviruses
Thiry, Etienne ULg; Dubuisson, J.; Pastoret, Paul-Pierre ULg

in Revue Scientifique et Technique (International Office of Epizootics) (1986), 5

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See detailPathogenic and molecular characterization of Pythium species inducing root rot symptoms of common bean in Rwanda
Nzungize, J.; Geps, P.; Buruchara, R. et al

in African Journal of Microbiology Research [=AJMR] (2011), 5

Detailed reference viewed: 29 (5 ULg)
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See detailPathogenic aspects of VTEC infections in ruminants
Goffaux, F; China, B; Stordeur, P et al

in Duffy, G; Garvey, P; McDowell, DA (Eds.) Verocytotoxigenic Escherichia coli (2001)

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See detailPathogenic role of matrix metalloproteases and their inhibitors in asthma and chronic obstructive pulmonary disease and therapeutic relevance of matrix metalloproteases inhibitors
Cataldo, Didier ULg; Guéders, Maud ULg; Rocks, Natacha ULg et al

in Cellular and Molecular Biology (2003), 49(6), 875-884

Matrix metalloproteinases (MMPs) are an at least 23 member family of calcium and zinc dependent enzymes implicated in many physiological and pathological processes. Asthma, chronic obstructive pulmonary ... [more ▼]

Matrix metalloproteinases (MMPs) are an at least 23 member family of calcium and zinc dependent enzymes implicated in many physiological and pathological processes. Asthma, chronic obstructive pulmonary disease (COPD) and emphysema are diseases associated with an inflammation of the airways and lung parenchyma. In this review, we focus on the role played by MMPs in the pathogenesis of inflammation, airway remodelling and alveolar destruction, depicting the observational studies in humans and the experimental studies in animal models. During the course of asthma, MM P-2,-8,-9 and TIMP-1 are expressed at baseline and the allergen exposure or exacerbations of the disease lead to an increase of MMP-9 secretion being at this time much higher than that of TIMP-1, allowing temporarily a matrix damage, possibly followed by abnormal repair. Animal models suggest a predominant role for MMP-9 and MMP-12 in the pathogenesis of pulmonary inflammation and link an absence of MMP-2 to an increased parenchymal inflammation. In COPD and emphysema, human studies indicate an over-secretion of MMP-2,-8,-9 and animal models point out MMP-1 and MMP-12 as being key players in the pathogenesis of emphysema. Taken together, these data identify specific MW inhibition as appropriate target for therapeutic intervention in asthma or COPD/emphysema. They also strongly argue against the widespread use of large spectrum non specific inhibitors that could be detrimental. [less ▲]

Detailed reference viewed: 58 (10 ULg)