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See detailA peculiar class of debris disks from Herschel/DUNES - A steep fall off in the far infrared
Ertel, S; Wolf, S; Marshall, J P et al

in Astronomy and Astrophysics (2012), 541

Aims. We present photometric data of debris disks around HIP 103389 (HD 199260), HIP 107350 (HN Peg, HD206860), and HIP 114948 (HD 219482), obtained in the context of our Herschel Open Time Key Program ... [more ▼]

Aims. We present photometric data of debris disks around HIP 103389 (HD 199260), HIP 107350 (HN Peg, HD206860), and HIP 114948 (HD 219482), obtained in the context of our Herschel Open Time Key Program DUNES (DUst around NEarby Stars). Methods. We used Herschel/PACS to detect the thermal emission of the three debris disks with a 3 sigma sensitivity of a few mJy at 100 um and 160 um. In addition, we obtained Herschel/PACS photometric data at 70 um for HIP 103389. Two different approaches are applied to reduce the Herschel data to investigate the impact of data reduction on the photometry. We fit analytical models to the available spectral energy distribution (SED) data. Results. The SEDs of the three disks potentially exhibit an unusually steep decrease at wavelengths > 70 um. We investigate the significance of the peculiar shape of these SEDs and the impact on models of the disks provided it is real. Our modeling reveals that such a steep decrease of the SEDs in the long wavelength regime is inconsistent with a power-law exponent of the grain size distribution -3.5 expected from a standard equilibrium collisional cascade. In contrast, a very distinct range of grain sizes is implied to dominate the thermal emission of such disks. However, we demonstrate that the understanding of the data of faint sources obtained with Herschel is still incomplete and that the significance of our results depends on the version of the data reduction pipeline used. Conclusions. A new mechanism to produce the dust in the presented debris disks, deviations from the conditions required for a standard equilibrium collisional cascade (grain size exponent of -3.5), and/or significantly different dust properties would be necessary to explain the potentially steep SED shape of the three debris disks presented. (abridged) [less ▲]

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See detailPeculiar hydrophobic properties of the 67-78 fragment of α-synuclein are responsible for membrane destabilization and neurotoxicity
Crowet, Jean-Marc ULg; Lins, Laurence ULg; Dupiereux-Fettweis, Ingrid ULg et al

Poster (2007, March 14)

α-synuclein is a 140 residue protein linked to Parkinson’s disease. Intraneural inclusions called Lewy bodies and Lewy neurites are mainly composed of α-synuclein aggregated in amyloid fibrils. Few years ... [more ▼]

α-synuclein is a 140 residue protein linked to Parkinson’s disease. Intraneural inclusions called Lewy bodies and Lewy neurites are mainly composed of α-synuclein aggregated in amyloid fibrils. Few years ago, tilted peptides have been detected in two other amyloidogenic proteins : the amyloid β peptide involved in Alzheimer’s disease, and the PrP protein linked to Creuztfeldt-Jakob’s disease. Tilted peptides are short protein fragments that adopt an oblique orientation when inserted into biological membranes. Tilted peptides are able to destabilize membranes. In this study, we predicted by sequence analysis and molecular modelling that the 67-78 fragment of α-synuclein is a tilted peptide. Like most of them, the α-syn 67-78 peptide is able to induce lipid mixing and leakage of unilamellar liposomes. A mutant designed by molecular modelling to decrease the destabilizing properties of the peptide was shown to be significantly less fusogenic. The neuronal toxicity was studied using human neuroblastoma cells and we demonstrated that the α-syn 67-78 peptide induces neurotoxicity. In conclusion, we have identified a tilted peptide in α-synuclein which could be involved in the toxicity induced during amyloidogenesis of α-synuclein. [less ▲]

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See detailPeculiar hydrophobic properties of the 67-78 fragment of α-synuclein are responsible for membrane destabilization and neurotoxicity
Crowet, Jean-Marc ULg; Lins, Laurence ULg; Dupiereux-Fettweis, Ingrid ULg et al

Poster (2006, December 18)

α-synuclein is a 140 residue protein linked to Parkinson’s disease. Intraneural inclusions called Lewy bodies and Lewy neurites are mainly composed of α-synuclein aggregated in amyloid fibrils. Few years ... [more ▼]

α-synuclein is a 140 residue protein linked to Parkinson’s disease. Intraneural inclusions called Lewy bodies and Lewy neurites are mainly composed of α-synuclein aggregated in amyloid fibrils. Few years ago, tilted peptides have been detected in two other amyloidogenic proteins : the amyloid β peptide involved in Alzheimer’s disease, and the PrP protein linked to Creuztfeldt-Jakob’s disease. Tilted peptides are short protein fragments that adopt an oblique orientation when inserted into biological membranes. Tilted peptides are able to destabilize membranes. In this study, we predicted by sequence analysis and molecular modelling that the 67-78 fragment of α-synuclein is a tilted peptide. Like most of them, the α-syn 67-78 peptide is able to induce lipid mixing and leakage of unilamellar liposomes. A mutant designed by molecular modelling to decrease the destabilizing properties of the peptide was shown to be significantly less fusogenic. The neuronal toxicity was studied using human neuroblastoma cells and we demonstrated that the α-syn 67-78 peptide induces neurotoxicity. In conclusion, we have identified a tilted peptide in α-synuclein which could be involved in the toxicity induced during amyloidogenesis of α-synuclein. [less ▲]

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See detailThe peculiar Of?p stars HD 108 and HD 191612
Nazé, Yaël ULg; Rauw, Grégor ULg; Walborn, N. R. et al

in Massive Stars and High-Energy Emission in OB Associations (2005, November 01)

The Of?p spectral category was introduced by Walborn in 1972 to describe peculiar stars which possess intense emission lines of C III 4647,4650,4651. Recently, two of them, HD 108 and HD 191612, were ... [more ▼]

The Of?p spectral category was introduced by Walborn in 1972 to describe peculiar stars which possess intense emission lines of C III 4647,4650,4651. Recently, two of them, HD 108 and HD 191612, were found to display spectacular line profile variations in the visible domain: these stars apparently alternate between two different spectral states (O6-O8). To discover the origin of this intriguing behaviour, a multiwavelength campaign was undertaken. In this context, the analysis of the X-ray emission is especially important since it provides crucial information for constraining the nature of these peculiar objects and testing conflicting models. We are therefore carrying out high-quality XMM-Newton observations of these stars and we present the results of the data obtained up to now. [less ▲]

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See detailThe Peculiar Of?p Stars HD 108 and HD 191612: The X-ray View
Nazé, Yaël ULg; Rauw, Grégor ULg; Walborn, N. R. et al

in The X-ray Universe 2005 (2006, January 01)

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See detail“Peculiar Sites of Amnesia: Recovering the ‘Eclipsed Figures of the Past’ in Francis Quamina Farrier’s The Slave and the Scroll and Michael Gilkes’s Couvade.”
Bada, Valérie ULg

in Bridges Across Chasms. Towards a Transcultural Future in Caribbean Literature. Ed. Bénédicte Ledent. (2004)

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See detailPeculiar Variable in Crux
Della Valle, M.; Hutsemekers, Damien ULg; Saviane, I. et al

in International Astronomical Union Circulars [=IAUCs] (2003), 8185

IAUC 8185 available at Central Bureau for Astronomical Telegrams.

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See detailPedagogical supervision and initial teachers’ education- an international research project
Albuquerque, Alberto; Pinheiro, Claudia; Aranha, Agata et al

Poster (2010, October)

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See detailPédagogie de l'écriture : un plan de travail pour apprendre à écrire les textes utilitaires
Dumortier, Jean-Louis ULg

in Revue de la Direction Générale de l’Organisation des Etudes (1987)

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See detailPédagogie de la lecture : comment aider à lire un roman complet ?
Dumortier, Jean-Louis ULg

in Revue de la Direction Générale de l’Organisation des Etudes (1979)

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See detailLa pédagogie de Niemeyer
de Landsheere, Gilbert ULg

Doctoral thesis (1960)

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See detailPédagogie expérimentale
de Landsheere, Gilbert ULg

in Bârsănescu, Stefan (Ed.) Dictionar de pedagogie contemporană (1969)

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See detailLa pédagogie expérimentale en Belgique
de Landsheere, Gilbert ULg

in International Review of Education (1967), 13(3), 298-305

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See detailLa pédagogie expérimentale
de Landsheere, Gilbert ULg

in Mialaret, Gaston; Vial, Jean (Eds.) Histoire mondiale de l'éducation. Vol. 4, De 1945 à nos jours (1981)

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See detailPédagogie nomade : une école de l’émancipation
Janvier, Antoine ULg; Toussaint, Benoit

in Brausch, Géraldine (Ed.) Petite histoire des pratiques démocratiques (ou comment mettre en œuvre l’égalité) (2012)

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See detailPédagogie Nomade: penser l'école et l'apprentissage depuis l'égalité
Janvier, Antoine ULg

Article for general public (2008)

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