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See detailNecrotising enterocolitis after administration of intravenous immunoglobulin in very low birth weight preterms: a retrospective study
Viellevoye, Renaud ULg; Rigo, Vincent ULg; Rigo, Jacques ULg

in Archives of Disease in Childhood (2008, November), 93(suppl II), 322

Background: Necrotising enterocolitis (NEC) is a major cause of mortality and morbidity in very low birth weight (VLBW) preterms. Pathogenesis remains unclear. Recently, we observed a few NEC occurring ... [more ▼]

Background: Necrotising enterocolitis (NEC) is a major cause of mortality and morbidity in very low birth weight (VLBW) preterms. Pathogenesis remains unclear. Recently, we observed a few NEC occurring within the 48 h following prophylactic administration of intravenous immunoglobulin (IVIgG). The aim of the present study was to evaluate the influence of IVIgG administration on the incidence of NEC in our neonatal intensive care unit (NICU). [less ▲]

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See detailNecrotizing varicella zoster virus folliculitis.
Nikkels, Arjen ULg; Pierard, Gérald ULg

in European Journal of Dermatology (2003), 13(6), 587-9

Although the usual clinical features of the varicella zoster virus (VZV)-induced lesions are readily recognized, the same virus is also responsible for a series of atypical lesions. A patient is presented ... [more ▼]

Although the usual clinical features of the varicella zoster virus (VZV)-induced lesions are readily recognized, the same virus is also responsible for a series of atypical lesions. A patient is presented with a single large infiltrated plaque on the abdomen. Although histology showed a necrotizing folliculitis surrounded by a dense perifollicular inflammatory infiltrate, the clinical presentation was not suggestive of folliculitis. Subtle cyto-histological clues for viral infection were suggested. Immunohistochemistry revealed the presence of VZV in the remnants of the follicular structures. This report underlines one of the protean clinical presentations of VZV skin infections and highlights the discreteness of typical VZV-related cyto-histological alterations. Complementary VZV identification methods such as immunohistochemistry, are helpful in order to increase the diagnostic accuracy of unusual VZV lesions. [less ▲]

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See detailNecrotoxigenic Escherichia coli : study of the roles of CNF2 and CDT-III toxins in an experimental model of infection in calves
Mainil, Jacques ULg

in Annales de Médecine Vétérinaire (2005), 149(Sp. Iss. SI), 46-48

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See detailNecrotoxigenic Escherichia Coli Type-2 Invade and Cause Diarrhoea During Experimental Infection in Colostrum-Restricted Newborn Calves
Van Bost, Sigrid; Roels, S.; Mainil, Jacques ULg

in Veterinary Microbiology (2001), 81(4), 315-29

There exists experimental evidence that necrotoxigenic Escherichia coli (NTEC) strains producing the cytotoxic necrotising factor 1 cause intestinal and extra-intestinal disease in piglets. On the other ... [more ▼]

There exists experimental evidence that necrotoxigenic Escherichia coli (NTEC) strains producing the cytotoxic necrotising factor 1 cause intestinal and extra-intestinal disease in piglets. On the other hand, no experimental model has been developed with NTEC strains producing the cytotoxic necrotising factor 2. In all, 14 colostrum-restricted calves were orally challenged with two strains isolated from the faeces of a diarrheic calf (B20a) or from the heart blood of a septicaemic calf (1404). All calves had diarrhoea which lasted until euthanasia in eight of them. In those calves, diarrhoea was correlated with the faecal excretion of the challenge strains. At necropsy, vascular congestion of the intestinal mucosa, hypertrophy of the mesenteric lymph nodes (MLN) and some congestion of the lungs were observed. Bacteriology confirmed the colonisation of the intestine by the challenge strains which were also recovered from the heart blood, the lungs and/or the liver. Histological sections confirmed enterocolitis, lymphadenitis and limited bronchopneumonia. In the intestinal tissue sections, bacteria testing positive in an in situ DNA hybridisation assay with a CNF2 probe were observed. Those results were confirmed by immunohistochemistry with a polyclonal anti-O78 and a monoclonal anti-F17b antisera. Three of the five control calves receiving either saline or a CNF(-), F17a strain (25KH09) had no clinical signs or lesions. The other two presented a profuse liquid diarrhoea but those calves were positive for the presence of K99(+) E. coli. In this model, both NTEC2 strains were thus, able to colonise the intestine, to cause long-lasting diarrhoea and to invade the blood stream with localisation in various internal organs in colostrum-restricted conventional newborn calves. [less ▲]

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See detailNecrotrophism is a quorum-sensing-regulated lifestyle in Bacillus thuringiensis.
Dubois, Thomas; Faegri, Karoline; Perchat, Stephane et al

in PLoS pathogens (2012), 8(4), 1002629

How pathogenic bacteria infect and kill their host is currently widely investigated. In comparison, the fate of pathogens after the death of their host receives less attention. We studied Bacillus ... [more ▼]

How pathogenic bacteria infect and kill their host is currently widely investigated. In comparison, the fate of pathogens after the death of their host receives less attention. We studied Bacillus thuringiensis (Bt) infection of an insect host, and show that NprR, a quorum sensor, is active after death of the insect and allows Bt to survive in the cadavers as vegetative cells. Transcriptomic analysis revealed that NprR regulates at least 41 genes, including many encoding degradative enzymes or proteins involved in the synthesis of a nonribosomal peptide named kurstakin. These degradative enzymes are essential in vitro to degrade several substrates and are specifically expressed after host death suggesting that Bt has an active necrotrophic lifestyle in the cadaver. We show that kurstakin is essential for Bt survival during necrotrophic development. It is required for swarming mobility and biofilm formation, presumably through a pore forming activity. A nprR deficient mutant does not develop necrotrophically and does not sporulate efficiently in the cadaver. We report that necrotrophism is a highly regulated mechanism essential for the Bt infectious cycle, contributing to spore spreading. [less ▲]

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See detailNederlands en Vlaams in Brussels perspectief
Vromans, Joseph ULg

Conference given outside the academic context (1992)

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See detailNederlands in de wereld - de wereld in het Nederlands
Vromans, Joseph ULg

Conference given outside the academic context (1992)

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See detailNederlands in het perspectief van uitspraakverwerving en contrastieve taalkunde
Rasier, Laurent ULg; Van Heuven, Vincent; Defrancq, Bart et al

Book published by Academia Press (2011)

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See detailHet Nederlands in Vlaanderen: van taalzorg naar taalbewustzijn
Vromans, Joseph ULg

Conference given outside the academic context (1998)

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See detailNederlands, de taal van een tweestromenland
Vromans, Joseph ULg

Conference given outside the academic context (2005)

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See detailNederlands-Frans in contrast. 2000 lexicologische valstrikken in het Frans voor Nederlandstaligen
Theissen, Siegfried ULg; Hiligsmann, Philippe; Rasier, Laurent ULg et al

Book published by Acco (2015)

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See detailHet Nederlandse lied door de eeuwen heen
Vromans, Joseph ULg

Conference given outside the academic context (1975)

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See detailHet Nederlandse literatuuronderwijs in de Waalse provincies als prescriptieve Landeskunde (1817-1900)
Steyaert, Kris ULg

in Konst, Jan; Hüning, Matthias; Holzhey, Tanja (Eds.) Neerlandistiek in Europa: Bijdragen tot de geschiedenis van de universitaire neerlandistiek buiten Nederland en Vlaanderen (2010)

This article focuses on three nineteenth-century literary histories written for French-speaking students of Dutch. The histories illustrate a concern on the part of the authors (J.F.X. Würth, F.A ... [more ▼]

This article focuses on three nineteenth-century literary histories written for French-speaking students of Dutch. The histories illustrate a concern on the part of the authors (J.F.X. Würth, F.A. Snellaert, and J. Stecher) not only with the teaching of Dutch literature and the development of a solid Dutch literary tradition but also with the presentation of their material in keeping with an underlying ideological framework. In each case their presentation was designed to reinforce a particular view of country and culture and of the respective roles of the Dutch, Flemish and Walloon peoples in the creation of a one-nation state. The differences between them reflect a change in the significance of Dutch literature as a result of political developments, leading in turn to a paradigm shift in the teaching of the subject at university. An analysis of the didactic aims and principles underlying the literary histories written by Würth, Snellaert and Stecher reveals the extent to which political allegiances and nationalist considerations determined their selection criteria and the organisation of their subject matter. Not surprisingly, the contemporary critical response to these study books shows a similar ideological bias. [less ▲]

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See detailNederlandse teksten I
Vromans, Joseph ULg; Theissen, Siegfried ULg

Book published by De Sikkel (1978)

Anthologie de textes non littéraires destinée aux classes supérieures de l'enseignement secondaire.

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See detailNederlandse teksten II
Vromans, Joseph ULg; Theissen, Siegfried ULg

Book published by De Sikkel (1978)

Anthologie de textes non littéraires destinée à l'enseignement universitaire

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See detailNederlandse uitspraakleer voor Franstaligen
Hiligsmann, Philippe; Rasier, Laurent ULg

Book published by Wolters-Plantyn (2006)

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See detailEen Nederlandstalige Shelley op de planken. De reconstructie van een vergeten schandaal
Steyaert, Kris ULg

in Neerlandica Extra Muros (2002), 40(3), 13-25

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See detailThe need for a consensus in the use of assessment tools for Alzheimer's disease: The Feasibility Study (assessment tools for dementia in Alzheimer Centres across Europe), a European Alzheimer's Disease Consortium's (EADC) survey
Diaz, S. P. R.; Gregorio, P. G.; Casado, J. M. R. et al

in International Journal of Geriatric Psychiatry (2005), 20(8), 744-748

Aims To ensure that all Alzheimer centres across Europe are capable of using a similar method of data collection. Information about the patient assessment tools used by each participating centre was ... [more ▼]

Aims To ensure that all Alzheimer centres across Europe are capable of using a similar method of data collection. Information about the patient assessment tools used by each participating centre was obtained and normal clinical practice in each EADC centre was documented by collecting data from routine new patient consultation. Methods Twenty new consecutive patients with objective memory impairment were recruited in each Alzheimer centre over 6 months. Each patient consultation was carried out according to routine clinical practice. Patient data were recorded using the anonymous patient protocol (demographic, diagnosis, MMSE score, patient assessment scales, and most prominent behavioural problem). Information about neuropsychological assessment tools used in each centre was take to account to harmonise research practice for future multicentre collaboration. Results Seven hundred and four patients from 36 memory clinics in 13 countries across Europe participated in the study. [M:F ratio 0.67. Mean age 75.4 SD 9.3 (51-102) Mean MMSE 21 SD 6 (0-30)] Five hundred and fifty-five patients had a clinical diagnosis of dementia [Alzheimer's disease (68.5%), vascular dementia (10.3%), frontal lobe dementia (5.6%), Lewy body dementia (4.1%), mixed dementia (5.6%)]. Duration of symptoms: 0-6 months 6.5%; 6-12 months 16.1%; 1-2 years 30.5%; 2-5 years 46.9%. Assessment scales used: Clinical Dementia Rating (CDR) 48.9%, Reisberg's Global Deterioration Scale (GDS) 38.6%, ADL/IADL (Lawton and Brody, 1969) 37.5%, Neuropsychological Inventory (NPI) 28.6%, Geriatric Depression Scale 22%, ADL (Katz et al., 1963) 19.2%, ADAS-Cog 14.9%, Cornell Scale for Depression 12.9%, Grober and Bushke Selective Reminding Test 11.5%, ADCS/ADL 7.7%. 64.8% of the patients experienced behavioural symptoms: apathy 13.6%; anxiety 12.8%; dysphoria 9.9%; irritability 7.8%; agitation 5.5%; hallucinations 3.6%; delusions 3.6%, sleep disorder 2.4%; desinhibition 2%. Conclusions The most common type of cognitive decline was Alzheimer's disease followed by mild cognitive impairment and vascular dementia. CDR, GDS Reisberg, and ADL/IADL were used widely (40-50%). The NPI, geriatric depression scale and ADL (Katz, 1963) were only used in 20% of the centres. We verified large differences in the tools use in the EADC centres to evaluate patients with dementia across Europe. There is a need for a consensus in the use of assessment tools for dementia in Alzheimer's centres in Europe. Copyright (c) 2005 John Wiley [less ▲]

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See detailThe need for a transparent, ethical, and successful relationship between academic scientists and the pharmaceutical industry: a view of the Group for the Respect of Ethics and Excellence in Science (GREES).
Bruyère, Olivier ULg; Kanis, J. A.; Ibar-Abadie, M*-E et al

in Osteoporosis International (2010), 21(5), 713-22

This paper provides recommendations for fair and unbiased relationship between academic scientists and the pharmaceutical industry. INTRODUCTION: Real or perceived problems in the relationship between ... [more ▼]

This paper provides recommendations for fair and unbiased relationship between academic scientists and the pharmaceutical industry. INTRODUCTION: Real or perceived problems in the relationship between academics and the industry have been the subject of much recent debate. It has been suggested that academic clinicians should sever all links with the industry-a view that is rarely challenged. METHODS: Academic experts and members of the pharmaceutical industry were invited to an expert consensus meeting to debate this topic. This meeting was organized by the Group for the Respect of Ethics and Excellence in Science. Conflict of interest, competing interest, right and duties of academic scientist, authorship, and staff and student education were discussed. RESULTS: Guidelines for a transparent, ethical, strong, and successful partnership between the academic scientist and the pharmaceutical industry have been provided. CONCLUSIONS: The Group support interactions between the industry and clinicians provided that it is transparent and ethical. [less ▲]

Detailed reference viewed: 27 (9 ULg)