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See detailNitrogen K-shell photoabsorption
Garcia, J; Kallman, T R; Witthoeft, M et al

in Astrophysical Journal Supplement Series (2009), 185

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See detailNitrogen leaching forecasting: modelling and measurements
Sohier, Catherine ULg; Vandenberghe, Christophe ULg; Dautrebande, Sylvia et al

in Bruthans, Jiri; Kovar, Karel; Hrkal, Zbynek (Eds.) International Interdisciplinary Conference on Predictions for Hydrology, Ecology and water Resources Management Using Data And Models To Benefit Society (2008)

European nitrate directive (CEE/91/676) imposes wide monitoring of Nitrogen in farmlands. The Walloon Region (South of Belgium – 750 000 ha of arable land) develops an original combination of methods to ... [more ▼]

European nitrate directive (CEE/91/676) imposes wide monitoring of Nitrogen in farmlands. The Walloon Region (South of Belgium – 750 000 ha of arable land) develops an original combination of methods to reach European objectives in this topic. On the one hand, water and nitrogen flows and balances are modelled, on the other hand, an Agricultural Surface Survey is put into practice to monitor nitrate nitrogen in the soil at the beginning of the leaching period. The Agricultural Surface Survey is constituted by a 30 reference farms network within more than 200 plots are monitored each in order to fix annual standards for nitrate profiles. Each year, about 1% of the Walloon farms are assessed about their good nitrogen management. Thanks to the existence of a useful database of nitrate profiles measured through six years in the whole Walloon Region, validation of the simulations in the vadose zone can be realised. The comparison of the measured data and the simulation shows a good accuracy of the EPICgrid model. [less ▲]

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See detailNitrogen-containing bisphosphonates can inhibit angiogenesis in vivo without the involvement of farnesyl pyrophosphate synthase.
Stresing, Verena; Fournier, Pierrick G; Bellahcene, Akeila ULg et al

in Bone (2011), 48(2), 259-66

Nitrogen-containing bisphosphonates (N-BPs) are widely used to block bone destruction associated with bone metastasis because they are effective inhibitors of osteoclast-mediated bone resorption. More ... [more ▼]

Nitrogen-containing bisphosphonates (N-BPs) are widely used to block bone destruction associated with bone metastasis because they are effective inhibitors of osteoclast-mediated bone resorption. More specifically, once internalized by osteoclasts, N-BPs block the activity of farnesyl pyrophosphate synthase (FPPS), a key enzyme in the mevalonate pathway. In addition to their antiresorptive activity, preclinical evidence shows that N-BPs have antiangiogenic properties. However, the exact reasons for which N-BPs inhibit angiogenesis remain largely unknown. Using different angiogenesis models, we examined here the effects of zoledronate, risedronate and three structural analogs of risedronate (NE-58025, NE-58051 and NE-10790) with lower potencies to inhibit FPPS activity. Risedronate and zoledronate were much more potent than NE-compounds at inhibiting both endothelial cell proliferation in vitro and vessel sprouting in the chicken egg chorioallantoic membrane (CAM) assay. In addition, only risedronate and zoledronate inhibited the revascularization of the prostate gland in testosterone-stimulated castrated rats. Moreover, as opposed to NE-compounds, risedronate and zoledronate induced intracellular accumulation of isopentenyl pyrophosphate (IPP) in endothelial cells by blocking the activity of the IPP-consuming enzyme FPPS. Thus, these results indicated that N-BPs inhibited angiogenesis in a FPPS-dependent manner. However, drug concentrations used to inhibit angiogenesis, both in vitro and in the CAM and prostate gland assays, were high. In contrast, a low concentration of risedronate (1 muM) was sufficient to inhibit blood vessel formation in the ex vivo rat aortic ring assay. Moreover, NE-58025 (which had a 7-fold lower potency than risedronate to inhibit FPPS activity) was as effective as risedronate to reduce angiogenesis in the rat aortic ring assay. In conclusion, our results suggest that low concentrations of N-BPs inhibit angiogenesis in a FPPS-independent manner, whereas higher drug concentrations were required to inhibit FPPS activity in vivo. [less ▲]

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See detailNITROGEN-RICH METAMORPHIC FLUIDS IN DEVONIAN METASEDIMENTS FROM BASTOGNE, BELGIUM
Darimont, Anne ULg; BURKE, E.; TOURET, J.

in Bulletin de Minéralogie (1988), 111(3-4), 321-330

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See detailNitroglycerin sensitises in healthy subjects CNS structures involved in migraine pathophysiology: evidence from a study of nociceptive blink reflexes and visual evoked potentials.
Di Clemente, Laura; Coppola, Gianluca; Magis, Delphine ULg et al

in Pain (2009), 144(1-2), 156-61

Nitroglycerin (NTG), a NO donor, induces an attack in migraine patients approximately 4-6 h after administration. The causative mechanisms are not known, but the long delay leaves room for a central ... [more ▼]

Nitroglycerin (NTG), a NO donor, induces an attack in migraine patients approximately 4-6 h after administration. The causative mechanisms are not known, but the long delay leaves room for a central effect, such as a change in neuronal excitability and synaptic transmission of various CNS areas involved in pain and behaviour including trigeminal nucleus caudalis and monoaminergic brain stem nuclei. To explore the central action of NTG, we have studied its effects on amplitude and habituation of the nociceptive blink reflex (nBR) and the visual evoked potential (VEP) before, 1 h and 4 h after administration of NTG (1.2 mg sublingual) or placebo (vehicle sublingual) in two groups of 10 healthy volunteers. We found a significant decrease in nBR pain and reflex thresholds both 1 and 4 h post-NTG. At the 4 h time point R2 latency was shorter (p=0.04) and R2 response area increased (p<0.01) after NTG but not after placebo. Habituation tended to become more pronounced after both NTG and placebo administration. There was a significant amplitude increase in the 5th VEP block (p=0.03) at 1h after NTG and in the 1st block (p=0.04) at 4 h. VEP habituation was replaced by potentiation at both delays after NTG; the change in habituation slope was significant at 1h (p=0.02). There were no significant VEP changes in subjects who received sublingual placebo. In conclusion, we found that in healthy subjects sublingual NTG, but not its vehicle, induces changes in a trigeminal nociceptive reflex and an evoked cortical response which are comparable to those found immediately before and during an attack of migraine. These changes could be relevant for the attack-triggering effect of NTG in migraineurs. [less ▲]

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See detailNitroglycerin-induced nNOS increase in rat trigeminal nucleus caudalis is inhibited by systemic administration of lysine acetylsalicylate but not of sumatriptan
Pardutz, A.; Szatmari, E.; Vecsei, L. et al

in Cephalalgia : An International Journal of Headache (2004), 24(6), 439-445

Systemic administration of nitroglycerin (NTG), a nitric oxide (NO) donor, in migraineurs triggers after several hours an attack of which the precise mechanisms are unknown. We found previously in rats ... [more ▼]

Systemic administration of nitroglycerin (NTG), a nitric oxide (NO) donor, in migraineurs triggers after several hours an attack of which the precise mechanisms are unknown. We found previously in rats that nitroglycerin (10 mg/kg s.c.) is able to increase significantly after 4 h the number of neuronal nitric oxide synthase (nNOS)-immunoreactive neurones in the cervical part of trigeminal nucleus caudalis. In the present experiments, we demonstrate that the 5-HT1(B/D) agonist sumatriptan (0.6 mg/kg s.c.) does not alter this phenomenon when given before NTG. By contrast, pretreatment with lysine acetylsalicylate (50 mg/kg i.m.) attenuates the NTG-induced nNOS expression in the superficial laminae of trigeminal nucleus caudalis. These findings suggest that effect of NTG on nNOS at a high dosage may involve the cycloxygenase pathway and that activation of the peripheral 5-HT1(B/D) receptors is not able to modify this effect. These data could help to better understand the role of NO in the pathogenesis of headaches and the action of antimigraine drugs. [less ▲]

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See detailNitrosomonas europaea-like bacteria detected as the dominant beta-subclass Proteobacteria ammonia oxidisers in reference and limed acid forest soils
Carnol, Monique ULg; Kowalchuk, G. A.; De Boer, W.

in Soil Biology & Biochemistry (2002), 34

Net nitrification in intact soil cores and the community of ammonia-oxidising bacteria were studied in acid Norway spruce (Picea abies (L.) Karst) and sessile oak (Quercus petraea (Matt. Lieb.)) soils ... [more ▼]

Net nitrification in intact soil cores and the community of ammonia-oxidising bacteria were studied in acid Norway spruce (Picea abies (L.) Karst) and sessile oak (Quercus petraea (Matt. Lieb.)) soils (Haute Ardenne, east Belgium) 18 months after treatment with 5 t ha(-1) dolomite lime. Liming caused a significant increase in nitrification in the upper soil layers (0.15 m) of both stands. DGGE (denaturing gradient gel electrophoresis) profiling after P-subclass ammonia oxidiser-specific polymerase chain reaction (PCR), combined with hybridisation and sequencing of excised DGGE bands revealed a dominance of Nitrosomonas europaea-like sequences, independent of soil horizon, tree species and lime treatment. A minority Nitrosospira-like population was detected, which showed affinity to nitrosospiras previously detected in acid soil. These results contrast with several reports suggesting a dominance of Nitrosospira-like organisms among ammonia oxidiser communities in acid soils. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailNitrous oxide and xenon prevent amphetamine-induced carrier-mediated dopamine release in a memantine-like fashion and protect against behavioral sensitization
David, Hélène N.; Ansseau, Marc ULg; Lemaire, Michelle ULg et al

in Biological Psychiatry (2006), 60(1), 49-57

Background. Amphetamine administration induces stimulation-independent dopainine release in the nucleus accumbens (NAcc) through reverse dopamine transport, a critical neurochemical event involved in its ... [more ▼]

Background. Amphetamine administration induces stimulation-independent dopainine release in the nucleus accumbens (NAcc) through reverse dopamine transport, a critical neurochemical event involved in its psycbostimulant action, and, furthermore decreases stimulation-dependent vesicular dopamine release. These effects may involve possible indirect glutamateigic mechanisms. Methods: We investigated the effiects of nitrous oxide and xenon, which possess antagonistic action at the N-methyl-D-aspartate (NMDA) receptor, on brain slices ex vivo on aniphetamine-induced changes in carrier-mediated and KCI-evoked dopamine release in the NAcc, and in vivo on ampbetamine-induced locomotor sensitization Results: Like the low-affininity NMDA receptor antagonist memantine, but not the prototypical compound MK-801, nitrous oxide and xenon at appropriate concentrations blocked both the increase in carrier-mediated dopamine release and locomotor sensitization produced by amphetamine. Conclusions: In contrast to what has generally been found using prototypical NMDA receptor antagonists, these data regarding the effect qf memantine, nitrous oxide, and xenon support the hypothesis that activation qf certain NMDA receptors (possibly those qf containing the NR1a/NR2D subunit) in the NAcc is involved in the ampbetamine-induced increase in carrier-mediated dopamine release and the development qf behavioral sensitization to amphetamine. Nitrous oxide, xenon, and memantine may be of therapeutic interest for treating drug dependence. [less ▲]

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See detailNitrous oxide emissions using quantum cascade laser spectrometry over a production crop: preliminary results
SALERNO, Giovanni ULg; Aubinet, Marc ULg; Joly, Joly et al

Poster (2013, September 18)

Amongst the greenhouse gases, nitrous oxide is recognized as having the greatest greenhouse forcing potential and as being the third in terms of radiative forcing. Agriculture is known to be the major ... [more ▼]

Amongst the greenhouse gases, nitrous oxide is recognized as having the greatest greenhouse forcing potential and as being the third in terms of radiative forcing. Agriculture is known to be the major anthropic emitter. This work is part of the FERTECOL project and its objective is to measure the emissions of nitrous oxide by a production crop with an eddy covariance system. The measurements extent over the growth period, cover a large range of climatic conditions and capture peak events associated with fertilization. The measurements, started in April 2013, are carried at the Lonzée Terrestrial Observatory (50°33'5.83"N- 4°44'46.22"E). On this year, the crop is planted with winter wheat. A Quantum Cascade Laser Absorption Spectrometer (QCLAS, GSMA, France) is used to measure nitrous oxide as well as water vapor and carbon dioxide at a frequency of 5 hertz. The fluxes are computed using the Eddy Covariance technique adapting standards quality and corrections procedures set up for CO2 fluxes to N2O. Standard meteorological measurements are performed in parallel. The analysis will present response of the fluxes to environmental variables as well as to fertilization events during the season. [less ▲]

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See detailNitrous oxide flux measurement with a closed chamber system : data treatment
Regaert, Donat ULg; Moureaux, Christine ULg; Heinesch, Bernard ULg et al

Poster (2015, January 30)

Nitrous oxide flux estimation from concentration measurements with a closed chamber system. Statistical data treatment to sort between relevant/irrelevant fluxes.

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See detailNitroxide mediated polymerization of methacrylates at moderate temperature
Detrembleur, Christophe ULg; Jérôme, Christine ULg; De Winter, Julien et al

in Polymer Chemistry (2014), 5(2), 335-340

In this communication we report the first homopolymerization of a variety of methacrylates by an NMP process at moderate temperature (40–50 °C), using an easily accessible and inexpensive nitroxide ... [more ▼]

In this communication we report the first homopolymerization of a variety of methacrylates by an NMP process at moderate temperature (40–50 °C), using an easily accessible and inexpensive nitroxide precursor. The combination of a low temperature azo-initiator with a hindered nitroso-compound produces a mixture of hindered nitroxides in the polymerization medium that act as efficient polymerization control agents. Results of Electron Spin Resonance (ESR) spectroscopy experiments combined with mass spectrometric studies support the proposed in situ NMP mechanism. The hindered structure of the nitroxides formed in situ is believed to be responsible for the efficiency of the process by allowing it to proceed at low temperature, therefore limiting the side reactions generally observed in NMP of methacrylates. [less ▲]

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See detailNitroxide reduction by electron transfer from the Eosin triplet state: electron paramagnetic resonance and flash photolysis studies
Seret, Alain ULg; Gandin, Ezio; Van de Vorst, Albert

in Journal of Photochemistry (1987), 38

The paramagnetism loss of nitroxide, photosensitized by eosin, was analysed in basic aqueous and micellar media using electron paramagnetic resonance (EPR) spectroscopy. In cetyltrimethylammonium bromide ... [more ▼]

The paramagnetism loss of nitroxide, photosensitized by eosin, was analysed in basic aqueous and micellar media using electron paramagnetic resonance (EPR) spectroscopy. In cetyltrimethylammonium bromide micelles and sodium bis(2-ethylhexyl)sulphosuccinate—n-heptane microemulsions, the paramagnetism decay curves are monoexponential. This is not the case in neat water and sodium dodecylsulphate micelles, for which more complex decays were recorded. It is concluded from flash photolysis measurements that the eosin triplet state is physically quenched by nitroxide and that the latter can be reduced by electron transfer either from the triplet state or from the semireduced form of eosin. This sequence of reactions was confirmed by experiments in micellar media and leads to an understanding of the EPR results. [less ▲]

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See detailThe Nitroxides in Polymerization
Olive, Gilles ULg; Göttgens, Christianne; Smulders, Wilfred et al

Poster (1999, May 20)

The Nitroxides in Polymerization arepresented here with explanation.

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See detailNiveau de contamination et spéciation des métaux lourds dans l'Oued Fès et l'Oued Sebou.
Bouezmarni, Mohamed ULg; Debbaut, Vincent ULg; Diouri, S. El Edrissi et al

Conference (2010)

Detailed reference viewed: 52 (7 ULg)