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Peer Reviewed
See detailL'optimisation du fonctionnement dans la vie quotidienne chez des patients Alzheimer à un stade débutant
Adam, Stéphane ULg

in Lettre du Neurologue (La) : le Courrier du Spécialiste (2000, April), (Hors-série),

Detailed reference viewed: 21 (1 ULg)
See detailOptimisation du plan parcellaire d'une exploitation agricole: une application de la theorie des graphes.
Dupont, Pascal ULg

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(3),

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See detailOptimisation du procédé de captage de CO2 dans des solvants aminés
Léonard, Grégoire ULg; Heyen, Georges ULg

in Récents Progrès en Génie des Procédés (2011), 101

Post-combustion carbon capture in amine solvents is currently one of the most promising technologies to prevent large quantities of CO2 from being emitted into the atmosphere. Two models (equilibrium and ... [more ▼]

Post-combustion carbon capture in amine solvents is currently one of the most promising technologies to prevent large quantities of CO2 from being emitted into the atmosphere. Two models (equilibrium and kinetics) have been built using the Aspen Plus software in order to optimise the capture process. A sensitivity study at constant CO2 capture rate has shown that the solvent concentration, its flow rate and its regenerating pressure have the largest influence on the process energy requirement. Different process flowsheet modifications such as the lean vapor compression, an absorber inter-cooling and the split-flow configuration have been simulated as well, decreasing the energy cost of the process. Tests on a pilot installation will be made that will help to validate this model. [less ▲]

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See detailOptimisation du protocole GPG
Hanzen, Christian ULg; Boudry, B.

in Point Vétérinaire (2003), 34(240), 44-46

Les facteurs susceptibles d’influencer les performances de reproduction permises par le protocole GPG sont multiples. L’apparition de l’oestrus et sa durée, la fréquence de l’ovulation, la croissance ... [more ▼]

Les facteurs susceptibles d’influencer les performances de reproduction permises par le protocole GPG sont multiples. L’apparition de l’oestrus et sa durée, la fréquence de l’ovulation, la croissance folliculaire, tout comme la progestéronémie, sont susceptibles d’être influencés par le stade du cycle auquel le protocole est mis en place. Le taux de gestation est d’autant plus élevé que la proportion d’animaux en anoestrus dans le troupeau est faible. Ceci explique sans doute en partie pourquoi la fertilité se trouve améliorée lorsque l’insémination suivant le traitement est effectuée après le 75e jour de lactation. De même, des résultats préliminaires confirment l’application potentielle du protocole au traitement des kystes ovariens. [less ▲]

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See detailOptimisation du traitement pharmacologique chez un patient avec un diabete de type 2 nouvellement diagnostique.
De Flines, Jenny ULg; Radermecker, Régis ULg; Jandrain, Bernard ULg et al

in Revue Médicale de Liège (2009), 64(2), 109-14

The diabetic patient, when type 2 diabetes is newly diagnosed, raises a therapeutic problem commonly observed in clinical practice, which is more complex than expected at first glance. The physician has ... [more ▼]

The diabetic patient, when type 2 diabetes is newly diagnosed, raises a therapeutic problem commonly observed in clinical practice, which is more complex than expected at first glance. The physician has to select the most appropriate antidiabetic oral agent as first choice, to consider the potential of using combined glucose-lowering therapies, to fix glycaemic target taking into account the individual benefit/risk ratio, and to offer the best protection against cardiovascular complications. The present clinical case illustrates such therapeutic problem describing a patient with a high cardiovascular risk profile who experienced a hypoglycaemic episode after the prescription of glibenclamide following the discovery of a moderate hyperglycaemia. [less ▲]

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See detailOptimisation du Trimaran MISTRAL (bateau rapide)
Rigo, Philippe ULg

Report (2000)

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See detailOptimisation et application de la RAPD (random amplified polymorphic DNA) dans un programme de selection recurrente chez le cotonnier (Gossypium spp.).
Vroh Bi, I.; Du Jardin, Patrick ULg; Mergeai, Guy ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(2),

Detailed reference viewed: 7 (1 ULg)
See detailOptimisation et caractérisation d’un extrait de cassis riche en antioxydants utilisable comme complément alimentaire
Tabart, Jessica ULg

Doctoral thesis (2011)

Blackcurrant (Ribes nigrum, family Saxifragaceae) produces fruits with a high antioxidant content. This shrub is much known for its strongly aromatic fruits. It is largely used in the industrial ... [more ▼]

Blackcurrant (Ribes nigrum, family Saxifragaceae) produces fruits with a high antioxidant content. This shrub is much known for its strongly aromatic fruits. It is largely used in the industrial production of syrups and of concentrates, it contains very high quantities of phenolic compounds, particularly anthocyanins. Blackcurrant buds and leaves are also used as a food complement for their tonic and diuretic properties, as well as for the treatment of rheumatic affections. With this plant, we tried to develop, on a laboratory scale, a flavonoid-rich extract, stable in time and to show several biological activities. Initially, different plant materials were compared (fruits, leaves, buds, from different cultivars harvested at different times) and the method of extraction were optimized. Lyophilised-leaf extracts obtained with the acetone-water-acetic acid mixture (70: 28: 2) show an excellent yield in antioxidant compounds. These freeze-dried extracts have also the advantage of being stable for several months. We characterized these extracts for their content in various classes of antioxidant molecules. The leaves and the buds yielded extracts containing mainly flavonols, flavanols and total phenolic compounds, as compared to berries. On the other hand, these fruits showed higher contents of ascorbic acid and anthocyanins. In a third part, we analyzed certain health-properties (antioxidant capacity, anti-inflammatory capacity and the properties in vasorelaxation process) of the blackcurrant extracts by using in vitro methods as well as cellular and isolated organ models. Our study highlighted the intracellular and the extracellular properties of the blackcurrant extract as radical scavenger. We also showed an inhibition of the myeloperoxydase activity in the activated neutrophils, and an activation of the vasorelaxation process of the blood-vessels (production of NO, modulation of the expression of ARNm eNOS in the endothelial cells and relaxing effect in isolated organ), and this, without presenting any toxic effects. In conclusion, the black currant leaf extract obtained through extraction in acetone-water- acetic acid mixture has many interesting properties for health-protection. This extract, rich in phenolic compounds and having a high antioxidant activity, can also modulate the activity of several enzymes involved in inflammation or in vascular motricity. [less ▲]

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See detailOptimisation et durabilité du traitement et de l’utilisation des eaux usées traitées en agriculture.
Chenini, F.; Trad, M.; Rejeb, S. et al

Report (2002)

Detailed reference viewed: 19 (3 ULg)
See detailOptimisation et Scale up des Fermentations de Production de Starters Lactiques.
Hamdi, M.; Hamza, S.; Amor, L. et al

Poster (1997, October 27)

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See detailOptimisation methods for initial/tool shape optimisation in metal forming processes
Ponthot, Jean-Philippe ULg; Kleinermann, Jean-Pascal

in International Journal of Vehicle Design (2005), 39(1-2), 14-24

Nowadays, the computer simulations of metal forming processes using the finite element method (FEM), have reached some level of maturity. Inverse problems purpose is to determine one or more of these ... [more ▼]

Nowadays, the computer simulations of metal forming processes using the finite element method (FEM), have reached some level of maturity. Inverse problems purpose is to determine one or more of these forming processes simulations input data, leading to a desired result. A first example that has now become classical is called parameter identification. It consists in evaluating the material parameters for material behaviour laws that would lead to the most accurate model, minimising the difference between experimental and numerical results. Another example, which is much less extensively described in the literature is the initial geometry and tool shape design, which consists in determining the initial shape of the specimen and/or the shape of the forming tools, in order to provide the desired final geometry after forming process. In this paper, we will show how some optimisation methods are able to solve this shape optimisation problems. We will also compare the efficiency of the proposed numerical methods. [less ▲]

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See detailOptimisation objective de paramètres en écoulements turbulents à surface libre sur maillage multibloc
Erpicum, Sébastien ULg

Doctoral thesis (2006)

The chronology of the theoretical and numerical researches outlined in this text is closely linked to our attachment to the physical modelling and to the practical concerns related to important hydraulic ... [more ▼]

The chronology of the theoretical and numerical researches outlined in this text is closely linked to our attachment to the physical modelling and to the practical concerns related to important hydraulic projects. The various applications carried out daily in the HACH , several of the being presented here, enabled to identify the ways to improve the existing numerical models of WOLF , as well as needs in new representation potentialities. The most of the developments described in this text were born from there, with as main objective to increase the capacities of the HACH’s models to help to the management and the design of hydraulic constructions. The hydraulic structures design, and the main part of the practical problems related to free surface flows hydrodynamics, requires both large and small scales studies, with reliable models locally suited to the represented phenomena, and thus variable in a single study depending on the particular point examined. On another hand, the shape and working optimization of hydraulic structures requires robust calibration tools allowing an objective approach. The latter have to be linked to simulation software with modelling capacities and computation times in agreement with the optimization requirements. Both these assessments specify the framework of the researches of this thesis and are at the roots of the definition of the objectives of this work. The first chapters of developments aim to describe the numerical framework of the WOLF package, and more particularly the 1D and 2D models. The rationalization of the computation times for large scale one-dimensional simulations is improved at this stage by implementing in the 1D solver an implicit time integration scheme in parallel to the existing explicit one. Similarly, some improvements have been brought to the solver WOLF2D. They concern the automatic extension of the computation domain regarding the wet and dry cells, the treatment of the slope and roughness source terms with an energetic approach, the water volume conservation as well as the reorganization of the equations resolution scheme in order to be totally free in the choice of the mathematical model to solve. The enrichment of the modelling potentialities of the WOLF software is then pursued by setting, implementing and applying an original turbulence model suited to the specific characteristics of the depth integrated flow modelling. In order to get over the computer and modelling limitations inherent in the use of a single mesh size to model a 2D domain, developments have been carried out to allow the realisation of two-dimensional computations on a structured Cartesian grid composed of several areas with different mesh sizes. In the same way, developments have been carried out to use the whole of the mathematical models available in WOLF2D simultaneously and automatically in a single simulation. The ultimate step of these developments consisted in linking the 1D and the 2D models in a single computation. Following all these steps of developments of hydrodynamic models, a suitable tool for parameters automatic calibration has been set up. Usable with any solver of the WOLF package, it allows the calibration of the whole of the physical parameters present in the hydrodynamic solvers, as well as the resolution of any calibration or optimization problem with these models. The final parallelisation of this Genetic Algorithms based tool opens the door to complex applications, such as the hydraulic design of structures on the basis of two-dimensional simulations of free surface turbulent flows on multiblock grid. At each step, the validation of the developments is rigorously performed through the comparison of the numerical results with those from test cases, theoretical or experimental, original or from the literature. Several practical applications examples illustrate the whole of the developed modelling potentialities and prove their applicability and efficiency facing the most of practical problems encountered by hydraulic engineers. [less ▲]

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See detailOptimisation of a new two-plate screening method for the detection of antibiotic residues in meat
Dang, Pham Kim; Degand, Guy ULg; Douny, Caroline ULg et al

in International Journal of Food Science & Technology (2011), 46

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See detailOptimisation of a semiochemical slow-release alginate formulation attractive towards Aphidius ervi Haliday parasitoids
Heuskin, Stéphanie ULg; Lorge, Stéphanie; Godin, Bruno et al

in Pest Management Science (2011)

BACKGROUND: Optimisation of alginate formulations is described in order to develop semiochemical (E-β-farnesene and E-β-caryophyllene) slow-release devices in biological control approaches by attracting ... [more ▼]

BACKGROUND: Optimisation of alginate formulations is described in order to develop semiochemical (E-β-farnesene and E-β-caryophyllene) slow-release devices in biological control approaches by attracting predators and parasitoids of aphids. Various formulation criteria were optimised with respect to semiochemical encapsulation capacity. Moreover, the optimised formulation was characterised by texturometry and confocal microscopy. The slow-release rates of semiochemicals were calculated in laboratory controlled conditions. The attractiveness of semiochemical formulations towards Aphidius ervi was demonstrated by olfactometry. RESULTS: Two major parameters were highlighted in encapsulation optimisation: the type of alginate (Sigma L) and the type of crosslinker ion (Ca2+). Other formulation parameters were optimised: ionic strength (0.5M), Ca2+ (0.2 M) and alginate (1.5%) concentrations and the maturation time of beads in CaCl2 solution (48 h). After physical characterisation of beads, semiochemical slow-release measurements showed that alginate formulations were efficient sesquiterpene releasers, with 503 μg of E-β-farnesene and 1791 μg of E-β-caryophyllene totally released in 35 days. The efficiency of semiochemical alginate beads as attractants for female parasitoids was demonstrated, with high percentages of attraction for semiochemical odours (88 and 90% for E-β-farnesene and E-β-caryophyllene respectively) and significant statistical results. CONCLUSION: Semiochemical alginate beads can be considered as efficient slow-release systems in biological control. These formulations could be very useful to attract aphid parasitoids on crop fields. [less ▲]

Detailed reference viewed: 101 (42 ULg)
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See detailOptimisation of blocked designs in fMRI studies
Maus, Bärbel ULg; van Breukelen, G. J. P.; Goebel, R. et al

Poster (2008)

Detailed reference viewed: 4 (1 ULg)