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See detailN1,N2,N3-trisisopentenyl guanidine and N1,N2-diisopentenyl guanidine, two cytotoxic alkaloids from Alchornea cordifolia (Schumach.& Thonn.) Mull. Arg. (Euphorbiaceae) root barks.
Mavar-Manga, H.; Chapon, David; Hoet, Sara et al

in Natural Product Communications [=NPC] (2006), 1(12), 1097-1100

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See detailN1-Fluoroalkyltryptophan analogues: synthesis and in vitro study as potential substrates for indoleamine 2,3-dioxygenase
Henrottin, Jean ULg; Zervosen, Astrid ULg; Lemaire, Christian ULg et al

in ACS Medicinal Chemistry Letters (2015)

ABSTRACT: Indoleamine 2,3-dioxygenase (hIDO) is an enzyme that catalyzes the oxidative cleavage of the indole ring of L-tryptophan through the kynurenine pathway, thereby exerting immunosuppressive ... [more ▼]

ABSTRACT: Indoleamine 2,3-dioxygenase (hIDO) is an enzyme that catalyzes the oxidative cleavage of the indole ring of L-tryptophan through the kynurenine pathway, thereby exerting immunosuppressive properties in inflammatory and tumoral tissues. The syntheses of 1-(2-fluoroethyl)-tryptophan (1-FETrp) and 1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)methyl)-tryptophan, two N1-fluoroalkylated tryptophan derivatives, are described here. In vitro enzymatic assays with these two new potential substrates of hIDO show that 1-FETrp is a good and specific substrate of hIDO. Therefore, its radioactive isotopomer, 1-[18F]FETrp, should be a molecule of choice to visualize tumoral and inflammatory tissues and/or to validate new potential inhibitors. [less ▲]

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See detailN2-cyano-N1-isopropyl-N3-[4-(3-methylphenylamino)-3-pyridylsulfonyl]guanidine
Dupont, L.; Masereel, B.; De Tullio, Pascal ULg et al

in Acta Crystallographica (1995), C51

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See detailNa channel purification by ion exchange and affinity chromatography
Bontemps, J; Grandfils, Christian ULg; Dandrifosse, Guy ULg et al

Poster (1984, May 30)

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See detailNa et K anormaux : A quoi faut-il penser?
Krzesinski, Jean-Marie ULg

Conference (2008, October 23)

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See detailNa(1.50)Mn(2.48)Al(0.85)(Po4)3, a New Synthetic Alluaudite-Type Compound
Hatert, Frédéric ULg

in Acta Crystallographica Section C-Crystal Structure Communications (2006), 62(Pt 1), 1-2

The first hydrothermal synthesis of an Al-rich alluaudite-type compound, namely disodium dimanganese aluminium tris(phosphate), which has been obtained at 1073 K and 0.1 GPa starting from the composition ... [more ▼]

The first hydrothermal synthesis of an Al-rich alluaudite-type compound, namely disodium dimanganese aluminium tris(phosphate), which has been obtained at 1073 K and 0.1 GPa starting from the composition Na2Mn2Al(PO4)(3), is reported. The crystal structure, which has been refined in the monoclinic C2/c space group, is identical to that of natural alluaudite. The structure consists of kinked chains of edge-sharing M1 and M2 octahedra, which contain Mn2+ and Al3+ ions. The chains are stacked parallel to {101} and are connected in the b direction by the P1 and P2 tetrahedra. These interconnected chains produce channels parallel to c, which contain the large A1 and AT sites occupied by Na+ and Mn2+ ions. [less ▲]

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See detailNa+,2Cl-,K+ cotransport system as a marker of antihypertensive activity of new torasemide derivatives
Masereel, B.; Ferrari, P.; Ferrandi, M. et al

in European Journal of Pharmacology (1992), 219

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See detailThe Na+/PO4 cotransporter SLC20A1 gene labels distinct restricted subdomains of the developing pronephros in Xenopus and zebrafish embryos.
Nichane, Massimo; Van Campenhout, Claude; Pendeville, Helene et al

in Gene Expression Patterns (2006), 6(7), 667-72

The embryonic pronephric kidneys of Xenopus and zebrafish serve as models to study vertebrate nephrogenesis. Recently, multiple subdomains within the Xenopus pronephros have been defined based on the ... [more ▼]

The embryonic pronephric kidneys of Xenopus and zebrafish serve as models to study vertebrate nephrogenesis. Recently, multiple subdomains within the Xenopus pronephros have been defined based on the expression of several transport proteins. In contrast, very few studies on the expression of renal transporters have been conducted in zebrafish. We have recently shown that the anterior and posterior segments of the zebrafish pronephric duct may correspond to the proximal tubule and distal tubule/duct compartments of the Xenopus and higher vertebrate pronephros, respectively. Here, we report the embryonic expression pattern of the Na(+)/PO(4) cotransporter SLC20A1 (PiT1/Glvr-1) gene encoding a type III sodium-dependent phosphate cotransporter in Xenopus and zebrafish. In Xenopus, SLC20A1 mRNA is expressed in the somitic mesoderm and lower level of expression is detected in the neural tube, eye, and neural crest cells. From stage 25, SLC20A1 is also detectable in the developing pronephros where expression is restricted to the late portion of the distal pronephric tubules. In zebrafish, SLC20A1 is transcribed from mid-somitogenesis in the anterior part of the pronephros where its expression corresponds to the rostral portion of the expression of other proximal tubule-specific markers. Outside the pronephros, lower level of SLC20A1 expression is also observed in the posterior cardinal and caudal veins. Based on the SLC20A1 expression domain and that of other transporters, four segments have been defined within the zebrafish pronephros. Together, our data reveal that the zebrafish and Xenopus pronephros have non-identical proximo-distal organizations. [less ▲]

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See detailNa-23 2D 3QMAS NMR and Si-29, Al-27 MAS NMR investigations of Laponite and synthetic saponites of variable interlayer charge
Delevoye, Laurent; Robert, Jean-Louis; Grandjean, Jean ULg

in Clay Minerals (2003), 38

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See detailThe Na-rich phosphate minerals from Malpensata granitic pegmatite, Piona, Lecco province, Italy
Vignola, Pietro; Hatert, Frédéric ULg; Fransolet, André-Mathieu ULg et al

in Acta Mineralogica-Petrographica, Abstract series (2010), 6

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See detailNa10(Na,Mn)7Mn43(PO4)36, a new synthetic fillowite-type phosphate.
Hatert, Frédéric ULg; Keller, Paul; Lissner, Falk et al

in Acta Crystallographica Section C-Crystal Structure Communications (2009), C65

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See detailNA2RE Project—The new atlas of amphibians and reptiles: new compilation and online system
Sillero, Neftalí; Campos, João; Oliveira, Marco Amaro et al

Conference (2013, August 24)

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See detailNa4(Na,Mn)4Mn22(H2O)[PO4]18, eine isotype Verbindung der Fillowit-Johnsomervilleit-Reihe
Keller, Paul; Lissner, Falk; Hatert, Frédéric ULg et al

in Zeitschrift für Kristallographie. New Crystal Structures (2001), 18

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See detailNa4Fe2+Fe3+(PO4)3, a new synthetic NASICON-type phosphate
Hatert, Frédéric ULg

in Acta Crystallographica Section E-Structure Reports Online (2009), E65

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See detailNaar de film? Ja, maar in het Nederlands of in het Vlaams?
Perrez, Julien ULg; Neven, Anneke

Conference (2012, August 28)

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See detailNaar een ethisch verantwoorde nanotechnologie? Over de plaats van ethiek in het huidige wetenschapsbeleid
Laurent, Brice; Van Oudheusden, Michiel ULg

in Ethiek & Maatschappij (2013), 14(4),

In this article, the authors describe how transhumanist ideas influence science nanotechnology policy in the United States. Subsequently, they distinguish different ways in which policymakers and ... [more ▼]

In this article, the authors describe how transhumanist ideas influence science nanotechnology policy in the United States. Subsequently, they distinguish different ways in which policymakers and scientists, both in the US and in Europe, address social and ethical implications of nanotechnology research and development. They discern two dominant approaches to responsible technology development: a rationalist approach, which separates scientific issues from ethical questions, and a procedural approach, which adheres to guiding moral principles for responsible technology development. They add to this classification an experimental approach, which directly intervenes in scientific practice. By indicating how concerned actors ethicize nanotechnology in different ways, the authors seek to clarify what is meant by ethics in nanotechnology development and incite reflection on the interconnectedness of ethics and new technologies. [less ▲]

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See detailNach der Scham: Nur noch Peinlichkeit. Beobachtungen zur literarischen „Psychogeschichte der Republik
Pontzen, Alexandra ULg

in Maiwald; Voigt, Heidrun; Casper, Sigrun Casper (Eds.) et al Konkursbuch scham (2005)

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See detailNach Italien! Goethe und die Folgen. Goethes Italienerfahrung im Spiegel moderner Belletristik
Pontzen, Alexandra ULg

Conference given outside the academic context (2004)

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