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See detailIntestinal Sucrase as a Novel Target Contributing to the Regulation of Glycemia by Prebiotics.
Neyrinck, Audrey M.; Pachikian, Barbara; Taminiau, Bernard ULiege et al

in PLoS ONE (2016), 11(8),

Inulin-type fructans (ITF) are known for their capacity to modulate gut microbiota, energy metabolism and to improve glycemia in several animal models of obesity, and in humans. The potential contribution ... [more ▼]

Inulin-type fructans (ITF) are known for their capacity to modulate gut microbiota, energy metabolism and to improve glycemia in several animal models of obesity, and in humans. The potential contribution of ITF as modulators of sugar digestion by host enzymes has not been evaluated yet. A sucrose challenge has been performed on naive mice fed a standard diet supplemented with or without native chicory inulin (Fibruline 5%) for 3 weeks. The area under the curve of glycemia as well as sucrase activity in the small intestine were lowered after inulin treatment. Pyrosequencing of the 16S rRNA gene confirmed important changes in gut microbiota (mostly in favor of Blautia genus) due to inulin extract supplementation. Interestingly, the suppressive effect of inulin extract on postprandial glycemia also occurred when inulin was directly added to the sucrose solution, suggesting that the effect on sucrose digestion did not require chronic inulin administration. In vitro tests confirmed a direct inhibition of sucrase enzyme by the inulin extract, thereby suggesting that native chicory inulin, in addition to its well-known prebiotic effect, is also able to decrease the digestibility of carbohydrates, a phenomenon that can contribute in the control of post prandial glycemia. We may not exclude that the sucrose escaping the digestion could also contribute to the changes in the gut microbiota after a chronic treatment with inulin. [less ▲]

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See detailIntestinal volvulus in cetaceans
Begeman, L.; St. Leger, J.; Blyde, D. et al

in Veterinary Pathology (2013)

Intestinal volvulus was recognized as the cause of death in 18 cetaceans, including 8 species of toothed whales (suborder Odontoceti). Cases originated from 11 institutions from around the world and ... [more ▼]

Intestinal volvulus was recognized as the cause of death in 18 cetaceans, including 8 species of toothed whales (suborder Odontoceti). Cases originated from 11 institutions from around the world and included both captive (n = 9) and free-ranging (n = 9) animals. When the clinical history was available (n = 9), animals consistently demonstrated acute dullness 1 to 5 days prior to death. In 3 of these animals (33%), there was a history of chronic gastrointestinal illness. The pathological findings were similar to those described in other animal species and humans, and consisted of intestinal volvulus and a well-demarcated segment of distended, congested, and edematous intestine with gas and bloody fluid contents. Associated lesions included congested and edematous mesentery and mesenteric lymph nodes, and often serofibrinous or hemorrhagic abdominal effusion. The volvulus involved the cranial part of the intestines in 85% (11 of 13). Potential predisposing causes were recognized in most cases (13 of 18, 72%) but were variable. Further studies investigating predisposing factors are necessary to help prevent occurrence and enhance early clinical diagnosis and management of the condition. [less ▲]

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See detailIntestinal-type endocervical adenocarcinoma in situ: an immunophenotypically distinct subset of AIS affecting older women.
Howitt, Brooke E.; Herfs, Michael ULiege; Brister, Kathriel et al

in The American journal of surgical pathology (2013), 37(5), 625-33

Conventional endocervical adenocarcinoma in situ (cAIS) is typically strongly and diffusely positive for p16 with a high Ki67 index consistent with its frequent association with high-risk human ... [more ▼]

Conventional endocervical adenocarcinoma in situ (cAIS) is typically strongly and diffusely positive for p16 with a high Ki67 index consistent with its frequent association with high-risk human papillomavirus (HPV) infection. The intestinal variant (iAIS) is less common, and its relationship to HPV infection has not been thoroughly examined. This study compares the clinicopathologic features, frequency of HPV infection, and expression of CDX2 and surrogate biomarkers of HPV infection (p16, Ki67) in cAIS with those of iAIS. A total of 86 cases with a diagnosis of AIS (49 iAIS, 37 cAIS) were identified from our multi-institutional files. Of these, 13 iAIS and 20 cAIS cases had slides and tissue available for histopathologic review, immunohistochemical analysis, and molecular tests. All 86 cases were used to evaluate clinical parameters; however, HPV DNA analysis and immunohistochemical analysis for p16, MIB-1, CDX2, and p53 were performed only on those cases with available slides or paraffin blocks. The average age at diagnosis was significantly higher in iAIS compared with that in cAIS (44.5 vs. 32.6 y) (P=0.0001). All 20 cAIS cases showed moderate to strong and diffuse p16 staining; however, only 9/13 iAIS cases showed this degree of p16 staining, whereas 4/13 (31%) iAIS cases showed weak and patchy distribution (P<0.02). Only 6/9 (67%) iAIS cases were positive for either HPV type 18 (5) or 33 (1), in contrast to 11/11 conventional cAIS (P=0.04). Similarly, 12/14 cAIS, but only 5/13 iAIS, cases showed a high Ki67 proliferative index. CDX2 was positive in all iAIS cases, whereas p53 was negative. Most iAIS cases are positive for high-risk HPV and show moderate to strong and diffuse p16 staining; however, a subset of iAIS shows variable staining with p16 and Ki67, is not associated with HPV, and occurs in a distinctly older age group suggesting an alternative pathogenesis. Awareness that iAIS can show variable staining for p16 and Ki67 is important when resolving problematic endocervical lesions, particularly in small biopsies with unusual p16 staining patterns. [less ▲]

Detailed reference viewed: 71 (3 ULiège)
See detailIntimate Class Acts: Friendship and Desire in Indian and Pakistani Women’s Fiction
Mirza, Maryam ULiege

Book published by Oxford University Press (2016)

Detailed reference viewed: 25 (1 ULiège)
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See detailIntimate partner violence: Does Alexithymia increase the risk of violence perpetration
Di Piazza, Laetitia ULiege; Kowal, Cécile; Blavier, Adelaïde ULiege

Poster (2015, May 28)

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See detailIntimate partner violence: Perseverance vs Dropout from treatment programs targeting male batterers
Di Piazza, Laetitia ULiege; Kowal, Cécile; Hodiaumont, Fabienne et al

Poster (2016, May 24)

Introduction: The Dropout phenomenon has been studied extensively in general psychotherapy and in more specific domains. Therapeutic programs for male batterers across Europe, United States or Canada also ... [more ▼]

Introduction: The Dropout phenomenon has been studied extensively in general psychotherapy and in more specific domains. Therapeutic programs for male batterers across Europe, United States or Canada also have their share of problems in their attempts to maintain users in treatment. The purpose of this study is to identify potential intrapsychic variables associated with dropout and completion of this kind of treatment. Method: Fifty one male offenders enrolled in a group treatment for domestic violence took part in the study (23 who abandoned and 28 who completed). Before the start of therapy, they were surveyed using questionnaires and structured clinical interview to collect sociodemographic data and to assess specific psychological variables, namely emotional distress (BDI), impulsive behavior (BIS-11), early relationship with their parents (PBI), life events (LEDS) and alexithymia (TAS-20), the inability to experience and express subjective emotions. Results: Correlational analysis showed that age, paternal parenting behaviors and the number of significant events reported in the past six months are the only variables correlated with treatment dropout. The younger the participants, the most likely they were to dropout of the group therapy. Moreover, men who completed treatment reported fewer difficulties in their life and less autonomy support by their father than men who prematurely terminated their therapy. Discussion: The present findings pose a serious challenge for all actors involved in specifics treatment programs. Indeed, if all individuals who committed violent acts have the same intrapsychic variables, how do we predict, especially retain and motivate, the users likely to dropout? [less ▲]

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See detailThe intimate relationship of gonadotropin-releasing hormone neurons with the polysialylated neural cell adhesion molecule revisited across development and adult plasticity.
Franceschini, Isabelle; Desroziers, Elodie ULiege; Caraty, Alain et al

in European Journal of Neuroscience (2010), 32(12), 2031-41

The neurohormone gonadotropin-releasing hormone (GnRH) is critical for all the aspects of reproductive life in vertebrates. GnRH is secreted by a small number of neurons dispersed within the preoptic ... [more ▼]

The neurohormone gonadotropin-releasing hormone (GnRH) is critical for all the aspects of reproductive life in vertebrates. GnRH is secreted by a small number of neurons dispersed within the preoptic-hypothalamic region. These neurons are derived from the embryonic olfactory pit. They then migrate along olfactory, vomeronasal and terminal nerves to their final destination. Classical approaches to study the regulation of GnRH secretion during the reproductive cycle have focused on the various neuronal inputs on GnRH neurons and their regulation by ovarian steroids. However, it is well known that steroids will change the microenvironment of neuronal networks and can induce plasticity and functional changes. In this review, we will focus on the intimate relationship of developing and adult GnRH neurons with the polysialylated form of neural cell adhesion molecule (PSA-NCAM), a major molecular actor in the morphogenesis and adult plasticity of the nervous system. We will first recapitulate the spatiotemporal relationship between PSA-NCAM and migrating GnRH neurons during embryogenesis of various vertebrate species and discuss its importance for GnRH neuron development as shown by various loss of function studies. In the adult, we will review the relationships between PSA-NCAM and GnRH neurons across various physiological states, and open the discussion to the use of new model systems that can help to unravel the function and mechanism of action of PSA-NCAM on GnRH neuronal network activity and GnRH release. [less ▲]

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See detailIntimités et inimitiés du religieux et du politique en Afrique,
Andre, Géraldine ULiege; Hilgers, Mathieu

Book published by Université de Bruxelles (2009)

The objective of this special issue of Civilisations is to shed a new light on the multiple relations between religion and processes of democratization in Africa. In the Semi-Authoritarian regimes under ... [more ▼]

The objective of this special issue of Civilisations is to shed a new light on the multiple relations between religion and processes of democratization in Africa. In the Semi-Authoritarian regimes under analysis, the political role played by religious movements appears to be growing, but does not seem univocal. Whether they oppose the power, criticize or legitimize it, these religious movements provide a growing symbolical support to the local people and help them analyze and interpret the political and social worlds. Nevertheless, their growing diversity and gradual breaking into a mosaique makes it complicated to carry out a very precise analysis of their political tendencies and impact. Is the establishment of a possible connection between social position, production and reception of religious ideologies one useful methodological way to clarify the relations of intimacy and enmity between religion and policy? In order to provide a number of answers, the articles of this special issue depart from case studies that illustrate the general mechanisms that shape the relations between religion and policy. [less ▲]

Detailed reference viewed: 21 (1 ULiège)
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See detailInto the deep. La profondeur comme attraction dans les productions des Studios Disney
Tomasovic, Dick ULiege

Conference (2013, November 08)

Depuis l’invention de la caméra multiplane en 1933 par l’ingénieur Bill Garity au sein des studios Disney, jusqu’à la création de la marque Disney Digital 3-D, en 2005, qui promeut le cinéma en relief ... [more ▼]

Depuis l’invention de la caméra multiplane en 1933 par l’ingénieur Bill Garity au sein des studios Disney, jusqu’à la création de la marque Disney Digital 3-D, en 2005, qui promeut le cinéma en relief stéréoscopique, les départements des effets spéciaux de la compagnie Disney se sont fortement investis dans la quête pour une restitution impressionnante, voire spectaculaire, de la profondeur de champ. Détaillant les illusions optiques de films aussi divers que The Old Mill (1937), Snow White and the Seven Dwarfs (1937), Bolt (2008), Alice in Wonderland (2010), ou Tron : Legacy (2011), cette intervention s’interroge également sur les présupposés idéologiques du simulacre de la profondeur chez Disney, qui se trouvent par ailleurs prolongés tant dans l’architecture des parcs à thèmes Disney que dans les dispositifs de nombre de leurs attractions. [less ▲]

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See detailL'intolérance environnementale idiopathique attribuée aux champs électromagnétiques (IEI-EMF)
Demaret, Isabelle ULiege

Poster (2014, October 16)

Depuis le début des années '80, des chercheurs étudient les plaintes des personnes se disant hypersensibles aux champs électromagnétiques (EMF), sous les normes recommandées. Les recherches n'ont ... [more ▼]

Depuis le début des années '80, des chercheurs étudient les plaintes des personnes se disant hypersensibles aux champs électromagnétiques (EMF), sous les normes recommandées. Les recherches n'ont cependant pas démontré que ces personnes étaient capables de détecter les EMF ni qu'elles présentaient des changements physiologiques en étant exposées aux EMF . L'OMS a regroupé ces plaintes sous le nom d'Intolérance Environnementale Idiopathique attribuée aux Champs Electromagnétiques (IEI-EMF). Au niveau médical, l'IEI-EMF est classée parmi les syndromes fonctionnels somatiques comme d'autres syndromes sans bases physiologiques démontrées. [less ▲]

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See detailIntorno ad una iscrizione posta sulla tomba di Ludolf Van Ceulen. Lettera del Sig. Eugenio Catalan a D. B. Boncompagni
Catalan, Eugène ULiege

in Bullettino di bibliografia e di storia delle scienze matematiche e fisiche (1874), 7

Detailed reference viewed: 17 (0 ULiège)
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See detailIntoxicatin à la cyproheptadine: un cas clinique
Piette, Caroline ULiege; Daron, Aurore; Leroy, Patricia et al

Conference (2005)

Detailed reference viewed: 13 (1 ULiège)
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See detailIntoxication par ingestion de champignons du genre Inocybe sp. chez un chien
Roels, Elodie ULiege; Peeters, Dominique ULiege; Gommeren, Kris ULiege

in Monde Vétérinaire (Le) (2012), (126), 5-8

Detailed reference viewed: 60 (3 ULiège)
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See detailIntoxication au CO: Mouvements athétosiques
Mohring, M.-P.; Dadoumont, Caroline ULiege; Daron, A. et al

in Journal de Pédiatrie belge (2007)

Detailed reference viewed: 46 (5 ULiège)
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See detailIntoxication oxycarbonée et gaz naturel
Lamy, Maurice ULiege; Noirfalise, A.

in Revue Médicale de Liège (1971), 26(4), 128-133

Detailed reference viewed: 34 (0 ULiège)
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See detailLes intoxications à l'oxyde de carbone (CO) et l'oxygénothérapie hyperbare (OHB)
Micheels, Jean ULiege; Colignon, M.; Lamy, Maurice ULiege

in Médecine et Hygiène (1989), 47

Detailed reference viewed: 11 (0 ULiège)
See detailIntoxications aiguës au méthanol et à l'éthylène glycol
Charlier, Corinne ULiege

Conference (2003)

Detailed reference viewed: 6 (0 ULiège)
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See detailIntoxications au dextropropoxyphène et au tramadol: bilan d'un an de recueil
Cohen, Sabine; Manchon, Monique; Artur, Michèle et al

in Annales de Toxicologie Analytique (2006), 2

La prescription de plus en plus fréquente du dextropropoxyphène (DP) et du tramadol, deux antalgiques opioïdes, a conduit les membres du groupe de travail "Toxicologie hospitalière" de la Société ... [more ▼]

La prescription de plus en plus fréquente du dextropropoxyphène (DP) et du tramadol, deux antalgiques opioïdes, a conduit les membres du groupe de travail "Toxicologie hospitalière" de la Société Française de Toxicologie Analytique (SFTA) à étudier leur toxicité clinique observée. L'étude a consisté en l'analyse des cas où l'une ou l'autre de ces molécules a été identifiée au décours d'un screening toxicologique réalisé durant l'année 2004 dans les laboratoires hospitaliers des membres de ce groupe. Pour chaque patient ont été recueillis les données démographiques, les concentrations plasmatiques en dextropropoxyphène, norpropoxyphène (NP) ou tramadol, la concentration plasmatique en paracétamol, les médicaments associés et les signes cliniques (digestifs, respiratoires, cardiaques et neurologiques). Aucune relation entre les concentrations plasmatiques de dextropropoxyphène et de paracétamol, ni entre celles de dextropropoxyphène ou de tramadol et la gravité clinique n'a été observée. Les concentrations plasmatiques observées en dextropropoxyphène sont faibles mais doivent attirer l'attention sur une éventuelle intoxication au paracétamol. Les concentrations plasmatiques en tramadol peuvent être élevées mais les intoxications sont dans l'ensemble peu sévères et les concentrations toxiques semblent très supérieures à la concentration de 1 mg/L. [less ▲]

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See detailIntoxications par le Temik® chez les animaux domestiques et sauvages : un problème alarmant en Wallonie
Delaunois, Annie; Lessire, Françoise ULiege; Ansay, M. et al

in Annales de Médecine Vétérinaire (1997), 141

Detailed reference viewed: 116 (14 ULiège)