Resistance of steel and composite connections submitted to a natural fire

Poster (2008, October 03)

Resistance testing challenges and reliability. MIC testing in the clinical laboratory today.

Conference (2003, October 03)

Resistance testing in children changing human immunodeficiency virus type 1 protease inhibitor

in Pediatric Infectious Disease Journal (2002), 21(3), 214-220

Objective. To assess genotypic and phenotypic resistance testing in HIV-1-infected children failing a first protease inhibitor (PI) therapy. Methods. In a multicenter observational study 21 children, ages ... [more ▼]

Objective. To assess genotypic and phenotypic resistance testing in HIV-1-infected children failing a first protease inhibitor (PI) therapy. Methods. In a multicenter observational study 21 children, ages 3 to 16 years, were given two reverse transcriptase inhibitors and one PI (mainly ritonavir, n = 18). They were subsequently treated with single or dual PI-based therapy (predominantly nelfinavir, n = 10, or ritonavir-saquinavir, n = 7). Resistance testing was performed at the time of therapy switch via direct sequencing and a recombinant virus susceptibility assay. Results. A total of 21 genotypic and 15 phenotypic resistance profiles were obtained. Most viruses displayed several reverse transcriptase mutations; however, 7 isolates maintained a wild-type protease. Ritonavir targeted the well-known pathway containing 82, 54, 46 and other secondary (nonactive site) mutations including T74A. No in vitro cross-resistance, i.e. greater than or equal to8-fold resistance to saquinavir or amprenavir, was encountered. Secondary mutations enhanced the prediction of ritonavir resistance (i.e. L10I) and in vitro nelfinavir cross-resistance (i.e. K20R/I conferred by primary (active site) resistance mutations. Either the 82, 54, 46 mutational genotype or the phenotype showing greater than or equal to8-fold nelfinavir cross-resistance predicted a poorer virologic response to nelfinavir salvage therapy. Conclusion. In a small cohort of heavily pretreated pediatric patients, resistance testing appears to predict the response to nelfinavir as salvage for a ritonavir-based therapy. This is further supported by the correlation between ritonavir-selected mutations and in vitro nelfinavir cross-resistance. Prospective studies should assess clinical outcome in children undergoing regimen changes based on resistance testing. [less ▲]

The Resistance to Freeze-Drying and to Storage Was Determined as the Cellular Ability to Recover Its Survival Rate and Acidification Activity

in International Journal of Microbiology (2010), 2010(625239),

The protective effects of the fatty acid composition and membrane action of the acidification activity of two strains of Lactobacillus kept at 20◦C were studied. The addition of sorbitol, monosodium ... [more ▼]

The protective effects of the fatty acid composition and membrane action of the acidification activity of two strains of Lactobacillus kept at 20◦C were studied. The addition of sorbitol, monosodium glutamate and glycerol during storage is causing the decline of acidification and increased concentrations of unsaturated fatty acids observed in both strains. The addition of sorbitol and monosodium glutamate does not alter the fatty acid composition, whatever the strain, but increases the resistance to freeze-drying of L. plantarum CWBI-B1419 and improves survival during storage. The addition of these preservatives and decreased activity of acidification improves the ratio unsaturated. These results indicate that the survival during storage and freeze-drying resistance are closely related to the composition of membrane fatty acids. This behaviour can be interpreted as an adaptation of L. plantarum B1419-CWBI supplemented by cryoprotectant additives such as sorbitol or monosodium glutamate sorbitol and monosodium glutamate as an additive. L. plantarum CWBI-B1419 presents a greater adaptation to culture conditions than L. paracasei ssp. paracasei LMG9192T. [less ▲]

La resistance varietale du niebe (Vigna unguiculata (L) Walp.) a Callosobruchus maculatus F. (Col. Bruchidae): evaluation et perspectives d'utilisation au Senegal.

in Internationaal Symposium over Fytofarmacie en Fytiatrie (1992), 44

Resistant prolactinomas

in Journal of Endocrinological Investigation (2011), 34

Resistencia desquiciada en El ejército iluminado de David Toscana

Conference (2009, December 13)

Resocialiser l'économie?

in Revue Internationale de l'Economie Sociale : Recma, Revue des Etudes Coopératives, Mutualistes et Associatives (2000), 275-276

La résolution de problèmes : analyse des pratiques de classe au cycle 5-8

in Actes du 4e congrès des chercheurs en éducation : le point sur la recherche en éducation en Communauté française (2006)

Résolution de problèmes arithmétiques : constats de recherches et pratiques de classes

in Les liens entre la pratique de la classe et la recherche en didactique des mathématiques, actes du colloque CIEAEM 50, Neuchâtel, 2-7 août 1998 (1999)