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See detailOctreotide (long-acting release formulation) treatment in patients with graves' orbitopathy: clinical results of a four-month, randomized, placebo-controlled, double-blind study.
Wemeau, J. L.; Caron, P.; Beckers, Albert ULg et al

in Journal of Clinical Endocrinology and Metabolism (2005), 90(2), 841-848

There are few effective, safe modalities for the management of Graves' ophthalmopathy (GO), a cell-mediated immune comorbidity of thyroid disease. Somatostatin analogs inhibit lymphocyte proliferation and ... [more ▼]

There are few effective, safe modalities for the management of Graves' ophthalmopathy (GO), a cell-mediated immune comorbidity of thyroid disease. Somatostatin analogs inhibit lymphocyte proliferation and activation, and accumulate in the orbital tissue of patients with GO. A double-blind, placebo-controlled study of a long-acting somatostatin analog [16 wk of long-acting release formulation of octreotide (octreotide-LAR)] was conducted in 51 patients with mild active GO with the aim of preventing deterioration and precluding the need for more aggressive therapeutic modalities, such as glucocorticoids or radiotherapy. No treatment effect was observed for the primary end point (a composite parameter defining the outcome as either success or failure on the basis of changes in class/grade of the severity index and Clinical Activity Scale of GO). The Clinical Activity Scale score was reduced for patients treated with octreotide-LAR, but without any significant difference with respect to patients receiving placebo. However, octreotide-LAR significantly reduced proptosis (as measured by exophthalmometry). This was associated with nonsignificant differences in favor of octreotide-LAR in a series of proptosis-related parameters: class III grade, opening of the upper eyelid, the difference in ocular pressure between primary position and upgaze, and extraocular muscle involvement. By magnetic resonance imaging evaluation the extraocular muscle volumes appeared reduced, but nonsignificantly. No significant correlation between the initial uptake of the somatostatin analog indium-labeled and the response to treatment was observed. One patient in the octreotide-LAR group developed gallstones. In this study, octreotide-LAR did not seem suitable to mitigate activity in mild GO. Surprisingly, it significantly reduced proptosis, one of the most debilitating symptoms of GO. Additional studies are warranted to define the benefit to risk ratio of the somatostatin analogs in this indication. [less ▲]

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See detailL'octréotide LP dans le traitement des ophtalmopathies basedowiennes incipiens : Evaluation prospective VS placebo
Wemeau, J. L.; Caron, P.; Rohmer, V. et al

in XXIème Congrès de la Société Française d'Endocrinologie - Abstract book (2004)

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See detailOculomotor guidance and capture by irrelevant faces
Devue, Christel ULg; Belopolsky, Artem; Theeuwes, Jan

in Plos ONE (2012)

Even though it is generally agreed that face stimuli constitute a special class of stimuli, which are treated preferentially by our visual system, it remains unclear whether faces can capture attention in ... [more ▼]

Even though it is generally agreed that face stimuli constitute a special class of stimuli, which are treated preferentially by our visual system, it remains unclear whether faces can capture attention in a stimulus-driven manner. Moreover, there is a long-standing debate regarding the mechanism underlying the preferential bias of selecting faces. Some claim that faces constitute a set of special low-level features to which our visual system is tuned; others claim that the visual system is capable of extracting the meaning of faces very rapidly, driving attentional selection. Those debates continue because many studies contain methodological peculiarities and manipulations that prevent a definitive conclusion. Here, we present a new visual search task in which observers had to make a saccade to a uniquely colored circle while completely irrelevant objects were also present in the visual field. The results indicate that faces capture and guide the eyes more than other animated objects and that our visual system is not only tuned to the low-level features that make up a face but also to its meaning. [less ▲]

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See detailOcytocine et dépression. Perspective psychoneuroendocrinienne.
Scantamburlo, Gabrielle ULg

in Encéphale (L') (2011), 37

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See detailOcytocine plamsatique et dimensions de personnalité dans la dépression unipolaire
Scantamburlo, Gabrielle ULg; Reggers, Jean; Hansenne, Michel ULg et al

in Encéphale (L') (2010), 36

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See detailOcytocine, hormone altruiste pleine de promesses ?
Scantamburlo, Gabrielle ULg

in Encéphale (L') (2012)

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See detailOd trzeciego sektora do przedsiebiorstwa spolecznego
Defourny, Jacques ULg

in Wygnański, Jan Jakub (Ed.) Antologia kluczowych tekstów Przedsiębiorstwo społeczne (2008)

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See detailOdanacatib anti-fracture efficacy and safety in postmenopausal women with osteoporosis: results from the phase III long-term odanacatib fracture trial
McClung, MR; Langdahl, B; Papapoulos, S et al

in Osteoporosis International (2014), 25(5), 573-575

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See detailOdanacatib anti-fracture efficacy and safety in postmenopausal women with osteoporosis: results from the phase III long-term odanacatib fracture trial
McClung, MR; Langdahl, B; Papapoulos, S et al

in Arthritis and Rheumatism (2014), 66(11), 987

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See detailThe Odd Man Out? Might Climate Explain The Lower Tree Alpha-Diversity Of African Rain Forests Relative To Amazonian Rain Forests?
Parmentier, I.; Malhi, Y.; Senterre, B. et al

in Journal of Ecology (2007), 95(5), 1058-1071

1. Comparative analyses of diversity variation among and between regions allow testing of alternative explanatory models and ideas. Here, we explore the relationships between the tree α-diversity of small ... [more ▼]

1. Comparative analyses of diversity variation among and between regions allow testing of alternative explanatory models and ideas. Here, we explore the relationships between the tree α-diversity of small rain forest plots in Africa and in Amazonia and climatic variables, to test the explanatory power of climate and the consistency of relationships between the two continents. 2. Our analysis included 1003 African plots and 512 Amazonian plots. All are located in old-growth primary non-flooded forest under 900 m altitude. Tree α-diversity is estimated using Fisher’s alpha calculated for trees with diameter at breast height ≥ 10 cm. Mean diversity values are lower in Africa by a factor of two. 3. Climate-diversity analyses are based on data aggregated for grid cells of 2.5 × 2.5 km. The highest Fisher’s alpha values are found in Amazonian forests with no climatic analogue in our African data set. When the analysis is restricted to pixels of directly comparable climate, the mean diversity of African forests is still much lower than that in Amazonia. Only in regions of low mean annual rainfall and temperature is mean diversity in African forests comparable with, or superior to, the diversity in Amazonia. 4. The climatic variables best correlated with the tree α-diversity are largely different in the African and Amazonian data, or correlate with African and Amazonian diversity in opposite directions. 5. These differences in the relationship between local/landscape-scale α-diversity and climate variables between the two continents point to the possible significance of an array of factors including: macro-scale climate differences between the two regions, overall size of the respective species pools, past climate variation, other forms of longterm and short-term environmental variation, and edaphics. We speculate that the lower α-diversity of African lowland rain forests reported here may be in part a function of the smaller regional species pool of tree species adapted to warm, wet conditions. 6. Our results point to the importance of controlling for variation in plot size and for gross differences in regional climates when undertaking comparative analyses between regions of how local diversity of forest varies in relation to other putative controlling factors. [less ▲]

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See detailThe odd nitrogen distribution in the daytime upper atmosphere of Venus.
Gérard, Jean-Claude ULg; Deneye, E.; Lerho, M.

in Bulletin of the American Astronomical Society (1987, January 01)

Not Available

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See detailL'odeur : question de sens ou de chimie
Romain, Anne-Claude ULg

Scientific conference (2014, August 28)

Afin de mesurer au mieux un paramètre, il faut préalablement connaître son identité. Concernant la métrologie de la pollution olfactive, toute la difficulté réside dans la particularité de cette pollution ... [more ▼]

Afin de mesurer au mieux un paramètre, il faut préalablement connaître son identité. Concernant la métrologie de la pollution olfactive, toute la difficulté réside dans la particularité de cette pollution. En effet, bien qu’associée à la pollution de l’air par les molécules volatiles qui la génèrent, elle en diffère par son effet sensoriel. Il va de soi que la pollution olfactive n’a de sens que par son odeur. Chaque individu a son propre odorat et dès lors sa propre interprétation de l’odeur. C’est cette subjectivité qui rend cette pollution si délicate à qualifier et à quantifier et qui la distingue de la pollution de l’air. De plus, contrairement à d’autres pollutions sensorielles de type sonore ou visuel, l’élément porteur ’est pas dans ce cas une grandeur physique telle que la longueur d’onde électromagnétique ou la variation de pression mais une grandeur physico-chimique particulière dont la mesure est beaucoup plus complexe. Un dictionnaire de langue française définit l’odeur comme « une émanation volatile, caractéristique de certains corps et susceptible de provoquer chez l’homme ou chez un animal des sensations dues à l’excitation d’organes spécialisés ». Cette définition de l’odeur met notamment en jeu deux disciplines : la chimie et la physiologie. En effet un chimiste pourrait présenter l’odeur comme un ensemble de molécules aux propriétés spécifiques qui inhalées par un individu génère une réaction, il s’intéresserait dès lors aux odorants alors qu’un physiologiste parlerait plutôt du stimulus induit par ces odorants et des mécanismes qui le provoquent au niveau des organes. Le traitement de l’information olfactive par le cerveau, la perception olfactive, conduit à plusieurs types de sensation. En effet, l’odeur perçue a trois grandes particularités : l’intensité, la qualité (ou la nature de l’odeur) et la tonalité hédonique ou affective (agrément/désagrément). A ces trois dimensions, il faut ajouter le caractère temporel du stimulus, dimension très utilisée dans le cadre de la pollution olfactive. [less ▲]

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See detailLes odeurs dans l'environnement : dimensions sensorielles et méthodes d'évaluation.
Nicolas, Jacques ULg; Romain, Anne-Claude ULg; Delva, Julien ULg

in Journal des Ingénieurs (Le) (2008), 109

Les différentes composantes de la nuisance olfactive ainsi que les diverses méthodes d'évaluation correspondantes sont présentées de manière concrète et en relation avec les normes existantes. L'article ... [more ▼]

Les différentes composantes de la nuisance olfactive ainsi que les diverses méthodes d'évaluation correspondantes sont présentées de manière concrète et en relation avec les normes existantes. L'article détaille les mesures d'intensité et de concentration de l'odeur en laboratoire, les techniques d'échantillonnage sur sources canalisées ou surfaciques, la méthode d'olfactométrie déambulatoire pour les sources fugitives et diffuses. Il présente également la notion d'exposition, traduite par la courbe représentant un percentile spatio-temporel de concentration d'odeur. Il est également montré que les riverains peuvent être impliqués dans le cadre d'enquêtes ou dans des réseaux de vigies pour estimer la nuisance. <br />Enfin, les potentialités des réseaux de capteurs-gaz (nez électroniques), bientôt commercialisés par Odometric, spin-off de l'unité de recherche de l'ULg, sont également présentées. [less ▲]

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See detailLes odeurs dans l'environnement: Résumé des législations européennes et nord-américaines
Nicolas, Jacques ULg; Otte, Benoît

Report (2005)

This short report synthesizes the policies concerning odour emissions applicable in Europe and North America. It was written in the frame of the project "Plan of air in Wallonia" aiming at inventory the ... [more ▼]

This short report synthesizes the policies concerning odour emissions applicable in Europe and North America. It was written in the frame of the project "Plan of air in Wallonia" aiming at inventory the policies, standards and measurement methods relative to air quality. [less ▲]

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See detailLes odeurs dans l'environnement: Sources d'odeur en Région Wallonne
Nicolas, Jacques ULg; Otte, Benoît

Report (2005)

The report was written in the frame of the project "Plan of air in Wallonia" aiming at inventory the policies, standards and measurement methods relative to air quality. The present report concerns more ... [more ▼]

The report was written in the frame of the project "Plan of air in Wallonia" aiming at inventory the policies, standards and measurement methods relative to air quality. The present report concerns more particularly the identification of possible sources of odour in Wallonia. Both the industrial and the agricultural sectors are investigated. [less ▲]

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See detailOdometers on regular languages
Berthé; Rigo, Michel ULg

in Theory of Computing Systems (2007), 40(1), 1-31

Odometers or "adding machines" are usually introduced in the context of positional numeration systems built on a strictly increasing sequence of integers. We generalize this notion to systems defined on ... [more ▼]

Odometers or "adding machines" are usually introduced in the context of positional numeration systems built on a strictly increasing sequence of integers. We generalize this notion to systems defined on an arbitrary infinite regular language. In this latter situation, if (A, <) is a totally ordered alphabet, then enumerating the words of a regular language L over A with respect to the induced genealogical ordering gives a one-to-one correspondence between N and L. In this general setting the odometer is not defined on a set of sequences of digits but on a set of pairs of sequences where the first (resp. the second) component of the pair is an infinite word over A (resp. an infinite sequence of states of the minimal automaton of L). We study some properties of the odometer such as continuity, injectivity, surjectivity, minimality,... We then study some particular cases: we show the equivalence of this new function with the classical odometer built upon a sequence of integers whenever the set of greedy representations of all the integers is a regular language; we also consider substitution numeration systems as well as the connection with beta-numerations. [less ▲]

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See detailOdor measurement : search for a proper analytical device
Nicolas, Jacques ULg

Conference (2010, March 30)

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See detailOdour annoyance assessments around landfill sites:methods and results
Nicolas, Jacques ULg; Romain, Anne-Claude ULg; Delva, Julien ULg et al

in Chemical Engineering Transactions (2008, June), 15

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See detailOdour emissions impact of on-farm biogas production with co-digestion : a case study in four European farms of the Great Region
Adam, Gilles ULg; Gennen, Jérome; Ubeda Sanchez, Yolanda et al

Conference (2013, December 06)

Detailed reference viewed: 38 (10 ULg)