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See detailNovel, Highly Efficient and Selective Ruthenium Catalysts for the Synthesis of Vinyl Esters from Carboxylic Acids and Alkynes
Nicks, Francois ULg; Aznar, Rozario; Sainz, Daniel et al

in European Journal of Organic Chemistry (2009), 2009(29), 5020-5027

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See detailLas novelas de la rebelión zapatista
Vanden Berghe, Kristine ULg

Book published by Peter Lang (2012)

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See detailNovelties in the multifaceted miconazole effects on skin disorders.
Quatresooz, Pascale ULg; Vroome, Valérie; Borgers, Marcel et al

in Expert Opinion on Pharmacotherapy (2008), 9(11), 1927-34

BACKGROUND: Miconazole nitrate is a time-honored antifungal of the imidazole class. OBJECTIVE: To revisit the various aspects of action of the drug in a dermatologic setting. METHOD: Review of the current ... [more ▼]

BACKGROUND: Miconazole nitrate is a time-honored antifungal of the imidazole class. OBJECTIVE: To revisit the various aspects of action of the drug in a dermatologic setting. METHOD: Review of the current peer-reviewed publications. RESULTS/CONCLUSION: Miconazole essentially inhibits 14alpha-demethylase, an enzyme required for the biosynthesis of ergosterol, which is the main sterol constituent of fungal cell membranes. Hence, toxic methylated sterols accumulate. Synthesis of triglycerides and phospholipids is also affected. In addition, miconazole also exhibits other ancillary mechanisms of action that probably participate in the therapeutic efficacy of the drug. The oxidative and peroxidative enzyme activities are altered leading to an intracellular build up of a toxic concentration of hydrogen peroxide. This may contribute to the deterioration of subcellular organelles and to cell necrosis. Farnesol synthesis is stimulated in Candida spp. leading to the prevention of yeast-to-mycelium formation. Overall, miconazole is fungistatic through its effect on ergosterol biosynthesis, but it may also have a fungicidal effect against a number of fungal species due to its effect on hydrogen peroxide accumulation. In addition, miconazole is active against a series of Gram-positive bacteria and has been shown to help the repair of the skin barrier function and to help mitigate some inflammatory cell reactions (such as in acne). To conclude, miconazole exerts multi-pronged effects both against pathogenic fungi and on skin physiology. [less ▲]

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See detailNovii etap issledovaniya stoyanki Kulbulak (po materialam raskopok 2009 g.)
Kolobova, K.A.; Flas, Damien ULg; Krivoshapkin, A. et al

in Issledovaniya pervobitnoï arkheologii Evrazii (2010)

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See detailNoviy verkhniepaleolititseckiy pamyatnik v doline reki Akhangaran (Uzbekistan)
Derevianko, A.P.; Kolobova, K.A.; Islamov, U.I. et al

in Problems of archaeology, ethnography and anthropology of Siberia and adjacent territories: material of the 15th annual session of the Institute of Archaeology and Ethnography, SBRAS (2007)

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See detailNOX3, a superoxide-generating NADPH oxidase of the inner ear
Banfi, Botond; Malgrange, Brigitte ULg; Knisz, Judit et al

in Journal of Biological Chemistry (2004), 279(44), 46065-46072

Reactive oxygen species (ROS) play a major role in drug-, noise-, and age-dependent hearing loss, but the source of ROS in the inner ear remains largely unknown. Herein, we demonstrate that NADPH oxidase ... [more ▼]

Reactive oxygen species (ROS) play a major role in drug-, noise-, and age-dependent hearing loss, but the source of ROS in the inner ear remains largely unknown. Herein, we demonstrate that NADPH oxidase (NOX) 3, a member of the NOX/dual domain oxidase family of NADPH oxidases, is highly expressed in specific portions of the inner ear. As assessed by real-time PCR, NOX3 mRNA expression in the inner ear is at least 50-fold higher than in any other tissues where its expression has been observed ( e. g. fetal kidney, brain, skull). Microdissection and in situ hybridization studies demonstrated that NOX3 is localized to the vestibular and cochlear sensory epithelia and to the spiral ganglions. Transfection of human embryonic kidney 293 cells with NOX3 revealed that it generates low levels of ROS on its own but produces high levels of ROS upon co-expression with cytoplasmic NOX subunits. NOX3-dependent superoxide production required a stimulus in the absence of subunits and upon co-expression with phagocyte NADPH oxidase subunits p47(phox) and p67(phox), but it was stimulus-independent upon co-expression with colon NADPH oxidase subunits NOX organizer 1 and NOX activator 1. Pre-incubation of NOX3-transfected human embryonic kidney 293 cells with the ototoxic drug cisplatin markedly enhanced superoxide production, in both the presence and the absence of subunits. Our data suggest that NOX3 is a relevant source of ROS generation in the cochlear and vestibular systems and that NOX3-dependent ROS generation might contribute to hearing loss and balance problems in response to ototoxic drugs. [less ▲]

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See detailThe NOy budget above Jungfraujoch: long-term evolution, family partition and model comparison
Demoulin, Philippe ULg; Mahieu, Emmanuel ULg; Zander, Rodolphe ULg et al

in Abstracts presented at the NDSC 2001 Symposium: Celebrating 10 years of atmospheric research (2001)

Based on high-resolution solar spectra recorded with FTIR instruments at the University of Liège laboratory located at the Jungfraujoch NDSC station (Swiss Alps, 46.5ºN, 8ºE, altitude 3580 m), the most ... [more ▼]

Based on high-resolution solar spectra recorded with FTIR instruments at the University of Liège laboratory located at the Jungfraujoch NDSC station (Swiss Alps, 46.5ºN, 8ºE, altitude 3580 m), the most important constituents making up the NOy family have been measured consistently since the mid-1980s. They include HNO3, NO, NO2 and ClONO2, which are analyzed in terms of their vertical column abundances above the site. Related trends have been determined and assessed statistically. Among these, only ClONO2 and NO2 reveal significant long-term trends. The combined column evaluation of NOy indicates a rate of change equal to (0.1+/-0.2) %/year, thus statistically undefined and barely consistent with the evolution of the source gas N2O. Trends derived from the observations will be compared critically with those deduced from a long-term run of a 2-D stratospheric model developed at the University of Oslo. The model includes full gaseous chemistry, PSCs and sulfate particles, which vary from year to year. Comparisons with similar data found in the literature are also discussed. [less ▲]

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See detailNoyaux de dattes: étude de la composition physico-chimique et des profils caractéristiques de la fraction lipidique
Besbes, S.; Blecker, Christophe ULg; Deroanne, C. et al

Conference (2004, March 21)

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See detailLes noyaux dʼhabitat en Belgique : situation en 1991 et évolution depuis 1970
Halleux, Jean-Marie ULg; Derwael, F.; Merenne-Schoumaker, Bernadette ULg

in Merenne-Schoumaker, Bernadette; Van der Haegen, H.; Van Hecke, E. (Eds.) Monographie "Urbanisation" 11A. Recensement Général de la Population et des Logements au 1er mars 1991 (1998)

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See detailLes noyaux dʼhabitat en Belgique. Situation en 2001 et évolution depuis 1981
Halleux, Jean-Marie ULg; Baltus, L.; Brück, L. et al

in Van Hecke, E.; Halleux, Jean-Marie; Decroly, J.-M. (Eds.) et al Noyaux dʼhabitat et régions urbaines dans une Belgique urbanisée. Enquête Socio-économique 2001. Monographies (n°9) (2009)

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See detailNoyaux dʼhabitat et régions urbaines dans une Belgique urbanisée. Enquête Socio-économique 2001. Monographies (n°9)
Van Hecke, E.; Halleux, Jean-Marie ULg; Decroly, J.-M. et al

Book published by SPF Economie, PME, Classes moyennes et Energie - Traduit en néerlandais (2009)

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See detailLa nozione di "partecipazione" nella Glossematica di Louis Hjelmslev
Cigana, Lorenzo ULg

Doctoral thesis (2014)

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See detailLe nozze (e l’imminente divorzio) di Filologia e Metrica
Valenti, Gianluca ULg

Conference (2011, November 03)

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See detailNozzle Capacity and Emissions of a Domestic Fuel Oil Boiler
Masy, Cédric; Ngendakumana, Philippe ULg

Conference (2005, September)

In order to investigate the influence of the nozzle capacity on the performance of fuel oil boilers, tests have been performed in transient and steady state regimes on our experimental boiler. The aim of ... [more ▼]

In order to investigate the influence of the nozzle capacity on the performance of fuel oil boilers, tests have been performed in transient and steady state regimes on our experimental boiler. The aim of the tests was to deduce the better couple nozzle - fuel injection pressure to reach the desired output power while producing fewer pollutants as possible. In short, a high fuel injection pressure associated with a low capacity nozzle is recommended. [less ▲]

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See detailNP-internal functions and extended uses of the 'type' nouns kind, sort, and type: Towards a comprehensive, corpus-based description
De Smedt, Liesbeth; Brems, Lieselotte ULg; Davidse, Kristin

in Facchinetti, Roberta (Ed.) Corpus linguistics 25 years on (2007)

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See detailLe NPI NH chez des sujets âgés déments et non déments
Ylieff, Michel ULg; Di Notte, David; Missotten, Pierre ULg et al

Poster (2006, September)

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See detailNPM Under Pressure: An Inquiry in Theory
Esposito, Giovanni ULg

Conference (2014)

This theoretical inquiry is undertaken on the basis of the problematization methodology proposed by Alvesson et Sandberg (2011) and deriving from a critical approach to management studies. In this paper ... [more ▼]

This theoretical inquiry is undertaken on the basis of the problematization methodology proposed by Alvesson et Sandberg (2011) and deriving from a critical approach to management studies. In this paper, problematization is adopted not only to question the fundamental assumptions of New Public Management (NPM) theory, but also to develop alternative assumptions to be explored in order to highlight a new way of approaching the managerial practices of public organizations. Starting from the in-house level of assumptions, NPM theoretical body has been gradually deconstructed by progressively increasing the level of abstraction and reaching the field level of assumption. The assumption’s content at each level of abstraction has been determined thanks to a continuum comparison between NPM and the Public Value Theory (PVT) school of thought. Because of its status of challenging theory, PVT has played the role of a theoretical reagent added to NPM system of thought in order to bring about a theoretical reaction enabling to spotlight problematic assumptions and generate further research questions. Such a “theoretical reaction” has shown that NPM is a functionalist theory based on a rationalistic approach to public organizations which are conceived as machines whose proper functioning depends on efficiency improvements to be achieved by means of a planning mode of management. [less ▲]

Detailed reference viewed: 59 (3 ULg)