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See detailIs Ambrosia artemisiifolia L. able to expand its invaded range northward in Western Europe?
Ortmans, William ULg; Mahy, Grégory ULg; Monty, Arnaud ULg

Conference (2016, September 13)

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of ... [more ▼]

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of central and southern France, and northern Italy. Northwards beyond the edge of this range, occurrence of casual population have been described for years, but these populations do not appear to become invasive, and the species does not seem to spread. This situation raises the following question: Has the invaded range reached a limit or will the species continue its invasion northwards? To answer this question, we followed two complementary approaches. First we set up an experimental garden in Belgium, 250 km north to the current invaded range, to see if the local climate allows the completion of the species reproduction cycle. Second, we performed an in situ measurement campaign in 12 population located beyond the edge, within the range but near the margin, and in the center of the invaded range. The aim of this campaign was to test whether the species had reduced plant performance towards range margins. The results showed that the species is able to establish populations with high growth rates in Belgium. Furthermore, the species expressed similar performance across the considered areas, even beyond the current invasion front. No evidence of processes constraining the invasion was found, which suggests a great potential for invasion north to the current invaded range. In this uncertain situation, awareness actions should be considered in the northern countries. [less ▲]

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See detailIs an alcoholic fixative fluid used for manual liquid-based cytology accurate to perform HPV tests?
Garbar, Christian; Mascaux, Corinne; De Graeve, Philippe et al

in Pathology and Laboratory Medicine International (2012), 4

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See detailIs an evidence-based approach unrealistic in NSCLC?
Coucke, Philippe ULg; Barthelemy, Nicole ULg; Bosquee, Léon ULg et al

in Belgian Journal of Medical Oncology [=BJMO] (2008), volume 2(6), 326-333

Summary Non-small cell lung cancer (NSCLC) is a heterogeneous tumour. A wide variety of treatment options is currently available. Surgery remains the mainstay of curative treatment and an operative ... [more ▼]

Summary Non-small cell lung cancer (NSCLC) is a heterogeneous tumour. A wide variety of treatment options is currently available. Surgery remains the mainstay of curative treatment and an operative approach will be selected in function of disease stage, tumour resectability and performance status of the patient. Adjuvant chemotherapy is considered standard at least for stage II and III disease. In stage III disease, resectability should be decided in function of the cytological/histological confirmation of N2 disease. If N2-disease cannot be highlighted at work-up, the patients are submitted to surgery followed by adjuvant chemotherapy. If patients are staged pN0-pN1 after surgery, ostoperative radiotherapy should not be given. However, if pN2 is discovered at surgery, there might be a place for postoperative radiotherapy but this still needs confirmation. In case of cytological/histological confirmation of pN2 disease prior to surgery, patients should not be operated but treated with a combination of oncomitant chemoradiotherapy. This treatment algorithm will be evaluated by reviewing the published evidence issued from randomized controlled trials. [less ▲]

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See detailIs Anosognosia in Alzheimer disease also observed for behavioural and personality changes?
Feyers, Dorothée ULg; Bastin, Christine ULg; Jaspar, Mathieu ULg et al

Poster (2010, May 28)

Anosognosia is a frequent manifestation in Alzheimer disease (AD) but its extent is not yet clearly established. While anosognosia for memory deficit has been widely reported, no study has simultaneously ... [more ▼]

Anosognosia is a frequent manifestation in Alzheimer disease (AD) but its extent is not yet clearly established. While anosognosia for memory deficit has been widely reported, no study has simultaneously explored anosognosia for personality and behaviour changes. We have tackled this question with 20 AD patients and 20 matched elderly subjects (ES). Participants (AD and ES) assessed their personality and their reactions in social situation both in current (S1) and past (S1_bef) time period. Assessment of these characteristics was also performed by relatives of the participants (R2 and R2_bef). Mann-Whitney test (p<0.05) were performed between discrepancy scores (calculated by comparing answers of subjects and relatives) obtained for AD and ES. A specific measure of anosognosia was also calculated by comparing S1 and R2. Statistical analyses demonstrated (1) that relatives of AD patients report more personality and behavioural changes across time (S1-S1_bef) than relatives of ES (R2–R2_bef); (2) that self-reported changes were not significantly different between AD patients and ES; (3) that anosognosia (S1-R2) was observed in AD patients for personality changes only. Results obtained support the hypothesis that anosognosia does not affect all domain in AD. Indeed, even if AD patients are no more able to assess their current personality, they perceive adequately their current reactions in social situations. [less ▲]

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See detailIs anthracene cofactor or spectator for the thermolysis of anthracenyl acylnitroso cycloadducts in the presence of a diene?
Monbaliu, Jean-Christophe ULg; Marchand-Brynaert, Jacqueline; Peeters, Daniel

in Tetrahedron Letters (2009), 50

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See detailIs aprotinin worth the risk in total hip replacement?
Janssens, Marc ULg; Joris, Jean ULg

in Anesthesiology (1994), 81(2), 518-519

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See detailIs artemisinin the only antiplasmodial compound in the Artemisia annua tea infusion? An in vitro study.
Mouton, Julia; Jansen, Olivia ULg; Frederich, Michel ULg et al

in Planta Medica (2013), 79(6), 468-70

In our ongoing investigation into Artemisia annua for the treatment of malaria, we decided to study the possibility that synergism might enhance the efficacy of artemisinin. Our main objective was to test ... [more ▼]

In our ongoing investigation into Artemisia annua for the treatment of malaria, we decided to study the possibility that synergism might enhance the efficacy of artemisinin. Our main objective was to test tea infusions and nonpolar extracts prepared from different A. annua varieties against Plasmodium falciparum in vitro in order to determine if synergism will increase the effectiveness of artemisinin in the samples as compared to pure artemisinin. We found that the IC50 of artemisinin in the tea and nonpolar extracts was not significantly different to the IC50 of pure artemisinin. We could show that the year and country of harvest or storage conditions did not have any influence on the activity and that it narrowly followed the concentration of artemisinin in all the extracts. In conclusion, based on these in vitro results, artemisinin seems to be the only active antiplasmodial compound in A. annua. [less ▲]

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See detailIs automatic disinfection between each endoscopy mandatory? Jury opinion
Delwaide, Jean ULg; Pelckmans, P.; Defrance, P. et al

in Acta Gastro-Enterologica Belgica (1998), 61(4), 429-430

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See detailIs bad group climate between girls a risky factor of aggression?
Mathys, Cécile ULg; Lanctôt, Nadine

Conference (2012)

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See detailIs behavior still a relevant variable ?
Richelle, Marc ULg

in Psychiatry, the state of the art. Vol.1. clinical psychopathology : nomenclature and classification (1985)

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See detailIs Belgium lagging behind in sustainability management? An international empirical analysis
Crutzen, Nathalie ULg; Hoerisch, Jacob

Conference (2013, September)

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See detailIs beta-blockade necessary to obtain diagnostic image quality at low radiation dose of coronary CT angiography using a 2nd generation 320-row scanner?
Ghekiere, Olivier; Djekic, Julien; El Hachemi, Mounia et al

Conference (2014, October 02)

PURPOSE To evaluate the effect of beta-blockade on coronary computed tomography angiography (CCTA) image quality and radiation dose using a second-generation 320-row scanner. MATERIAL AND METHODS 200 ... [more ▼]

PURPOSE To evaluate the effect of beta-blockade on coronary computed tomography angiography (CCTA) image quality and radiation dose using a second-generation 320-row scanner. MATERIAL AND METHODS 200 patients (mean age 60± 3, range 20-86 years;92 females) were included in this prospective study, including 97 patients without beta-blockade and 103 patients with beta-blockade. Target heart rate (HR) in this 2nd group was < 75 bpm, enabling single heartbeat scan, the threshold for a dual heart beat scan was HR < 100 bpm. Image quality in coronary segments ≥ 1.5 mm was evaluated by 2 readers using a four-point scale from grade 1, no artifact to 4, unevaluable. Effects of radiation dose, caliber, HR, arrhythmia, age, BMI, scan length, number of heartbeat/scan, coronary stent, beta-blockade, coronary calcifications, kilovoltage(kV), tube current(mA), and signal to noise ratio(SNR), defined as the ratio between the mean attenuation and the standard deviation in the aorta of on radiation dose (mSv) and image quality were analyzed by using regression analysis. RESULTS: Image quality (grade 1 or 2) was diagnostic in 99,9% and interobserver agreement was good (κ=0,61). Regression analysis of the radiation dose (mean 1,5±0.2 mSv) shows that there is a negative impact of BMI (mean 27,1±2,0kg/m²), arrhythmia during acquisition (n =8), Agatston score, scan length, number of heart beat/scan and the age on the radiation dose, whereas vessel caliber, number of heart beat/scan, age, HR(mean 61,4 beats/min) and SNR negatively impacted the image quality (p-values < 0.05). Beta-blockade impacted neither radiation dose nor image quality (p >0.05). CONCLUSION Using a second generation 320-row scanner, beta-blockers does not result in a better coronary image quality or lower radiation dose. [less ▲]

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See detailIs bounce juggling easier in a parabolic billiard than in a wedge
Chang, Dong Eui; Ronsse, Renaud; Sepulchre, Rodolphe ULg

in Proceedings of the 5th Euromech nonlinear dynamics conference (2005)

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See detailIs brain activity during a Stroop inhibitory task modulated by the kind of cognitive control required?
Collette, Fabienne ULg; D'Ostilio, Kevin ULg; D'Argembeau, Arnaud ULg et al

Conference (2011)

Performance on the Stroop task is associated to a large antero-posterior cerebral network involving notably the anterior cingulate and dorsolateral prefrontal cortex. In this study, we used a mixed-BOLD ... [more ▼]

Performance on the Stroop task is associated to a large antero-posterior cerebral network involving notably the anterior cingulate and dorsolateral prefrontal cortex. In this study, we used a mixed-BOLD-fMRI design (N=25) to determine the neural substrates of inhibitory functioning in a Stroop task according to contextual information. Consequently, two task-contexts were created: (1) congruent context with a majority of facilitator items, (2) non-congruent context with mainly interfering items. Based on the dual cognitive control model, we postulated that the non-congruent blocks will involve proactive control, which is anticipatory, sustained, and involved when a large number of interfering items are successively presented. On the contrary, congruent blocks were assumed to involve reactive control, which occurs when few interfering items are presented, and just after the presentation of these items only. On this basis, we hypothesized that the kind of cognitive control modulates cerebral activity associated to inhibitory functioning. For behavioral data, we obtained faster response times for interfering items in the non-congruent vs. congruent condition, indicating proactive control specific to the congruent condition only. Functional neuro-imaging data showed an increased transient activity for interfering vs neutral items in a fronto-parietal network more important in the congruent than in the neutral condition. A similar contrast in the non-congruent condition showed no significant brain activity at the statistical threshold used. These data indicate the existence of a modulation of the cerebral areas associated to inhibitory functioning according to the kind of cognitive control necessary to perform the task. [less ▲]

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See detailIs brain estradiol a hormone or a neurotransmitter?
Balthazart, Jacques ULg; Ball, G. F.

in Trends in Neurosciences (2006), 29(5), 241-249

Mounting evidence indicates that, besides their well-known hormonal mode of action at the genetic level, estrogens such as 17 beta-estradiol also influence brain function by direct effects on neuronal ... [more ▼]

Mounting evidence indicates that, besides their well-known hormonal mode of action at the genetic level, estrogens such as 17 beta-estradiol also influence brain function by direct effects on neuronal membranes. Experimentally induced rapid changes in estradiol bioavailability in the brain have been shown to alter the expression of male sexual behavior significantly within minutes - probably too quickly to be accounted for by conventional genetic mechanisms. In parallel, recent studies indicate that aromatase, the enzyme that converts testosterone to estradiol in the brain, is expressed in presynaptic terminals and modulated within minutes by Ca2+-dependent phosphorylation. In this article, we develop the hypothesis that brain estrogens display many, if not all, functional characteristics of neuromodulators or even neurotransmitters. [less ▲]

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See detailIs Büchi's theorem useful for you?
Rigo, Michel ULg

Conference (2015, May 28)

Almost a century ago, Presburger showed that the first order theory of the natural numbers with addition is decidable. Following the work of Büchi in 1960, this result still holds when adding a function ... [more ▼]

Almost a century ago, Presburger showed that the first order theory of the natural numbers with addition is decidable. Following the work of Büchi in 1960, this result still holds when adding a function $V_k$ to the structure, where $V_k(n)$ is the largest power of $k\ge 2$ diving $n$. In particular, this leads to a logical characterization of the $k$-automatic sequences. During the last few years, many applications of this result have been considered in combinatorics on words, mostly by J. Shallit and his coauthors. In this talk, we will present this theorem of Büchi where decidability relies on finite automata.Then we will review some results about automatic sequences or morphic words that can be proved automatically (i.e., the proof is carried on by an algorithm). Finally, we will sketch the limitation of this technique. With a single line formula, one can prove automatically that the Thue-Morse word has no overlap but, hopefully, not all the combinatorial properties of morphic words can be derived in this way. [less ▲]

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See detailIs Büchi's theorem useful for you? (for an audience of logicians)
Rigo, Michel ULg

Conference (2017, January 17)

Almost a century ago, Presburger showed that the first order theory of the natural numbers with addition is decidable. Following the work of B\"uchi in 1960, this result still holds when adding a function ... [more ▼]

Almost a century ago, Presburger showed that the first order theory of the natural numbers with addition is decidable. Following the work of B\"uchi in 1960, this result still holds when adding a function $V_k$ to the structure, where $V_k(n)$ is the largest power of $k\ge 2$ diving $n$. In particular, this leads to a logical characterization of the $k$-automatic sequences. During the last few years, many applications of this result have been considered in combinatorics on words, mostly by J. Shallit and his coauthors. In this talk, we will present this theorem of B\"uchi where decidability relies on finite automata. Then we will review some results about automatic sequences or morphic words that can be proved automatically (i.e., the proof is carried on by an algorithm). Finally, we will sketch the limitation of this technique. With a single line formula, one can prove automatically that the Thue-Morse word has no overlap but, hopefully, not all the combinatorial properties of morphic words can be derived in this way. We will not assume any background in combinatorics on words from the audience. [less ▲]

Detailed reference viewed: 15 (3 ULg)