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See detailOptiVal: Vers de nouveaux outils de gestion pour les éleveurs laitiers wallons, Prédire la réussite à l’insémination
Laloux, Laurent; Bastin, Catherine ULg; Glorieux, Géry et al

Poster (2008, January 23)

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See detailOptiVal: Vers de nouveaux outils de gestion pour les éleveurs laitiers wallons, Prédire la réussite à l’insémination
Laloux, Laurent; Bastin, Catherine ULg; Glorieux, Géry et al

in 13ième Carrefour des Productions animales: L'Elevage des ruminants en question: vérités et contre-vérités: Gembloux, le 23 janvier 2008 (2008)

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See detailOptiView − A Powerful and Flexible Decision Tool Optimising Space Allocation in Shipyard Workshops
Caprace, Jean-David ULg; Bair, Frédéric ULg; Losseau, Nicolas ULg et al

in Conference on Computer Applications and Information Technology in the Maritime Industries (COMPIT) (2008, May)

This paper presents new developments to maximize the number of ship blocks and ship sections produced in various workshops of shipyards during a certain time window. The visualization tool OptiView® was ... [more ▼]

This paper presents new developments to maximize the number of ship blocks and ship sections produced in various workshops of shipyards during a certain time window. The visualization tool OptiView® was developed to support users to improve the space utilization and workshop productivity. The software is coupled with a heuristic optimisation solver. The paper describes the approach to the space allocation problem and gives three application examples. [less ▲]

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See detailOptoacoustic specific detection of prostate cancer using functionalized gold nanorods
Fleron, Maximilien ULg; Schol, Daureen ULg; Greisch, Jean-François et al

Poster (2007, November 16)

A major challenge in prostate cancer oncology is to develop more accurate imaging assessments than those currently available. Indeed, an efficient imaging technique which significantly improves the ... [more ▼]

A major challenge in prostate cancer oncology is to develop more accurate imaging assessments than those currently available. Indeed, an efficient imaging technique which significantly improves the sensitivity and specificity of the diagnostic and predicting the cancer behaviour would be extremely valuable. This project intends to prove the concept of using optoacoustic imaging in combination with biologically functionalized nanoparticles as an integrated biosensor based system for the production of specific and sensitive data for accurate diagnosis of prostate cancer. This concept results on the use of contrast agents which transform an incident luminous energy into local heating inducing a pressure wave detectable by acoustic (echography). For the optoacoustic detection, the nanoparticles used must present a maximum of absorption in the optical transparency window of the human tissues in order to allow their and subsequently the tissue specific excitations while avoiding unwanted destructive energy transfers. According to these characteristics (energy transfer by thermoelastic reaction), rod-like gold nanoparticles (stick form) with a maximum of absorption towards 760 nm were produced by using a “bottom-up” approach with dynamic templates (surfactant). These nanoparticles are then coupled with an antibody directed against the cancerous cells to guarantee the specific detection of the particles. The development of the biosensor is firstly performed to target the Prostate Specific Membrane Antigen (PSMA), a transmembrane protein considered as a suitable biomarker for prostate cancer. Detection and localisation of PSMA on LNCaP fixed cell surface was performed by immunostainning on monolayer cell culture and on spheroid slices. Then, by backscattered electron (BSE) microscopy analysis and two-photon luminescence imaging, detection of nanoparticles on fixed and living cell surface shows the successful binding of the biosensor to the cells expressing PSMA. In prospect, the detection of the biosensor will be tested on spheroids, on human biopsies and finally on in vivo models (mouse xenograft models). [less ▲]

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See detailOptoacoustic specific detection of prostate cancer using functionalized gold nanorods
Fleron, Maximilien ULg; Schol, Daureen ULg; Greisch, Jean-François et al

Poster (2007, October 10)

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See detailOptoacoustic specific detection of prostate cancer using functionalized gold nanorods
Schol, Daureen ULg; Fleron, Maximilien ULg; Greisch, Jean-François et al

Poster (2008, March 12)

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See detailOPTOPUS observations of Halley’s comet
Lund, G.; Surdej, Jean ULg

in The Messenger (1986), 43

The multiobject spectrograph OPTOPUS, for use at the 3.6-m ESO telescope with the CCD detector, is described, and preliminary results of spectra obtained in December 1985 of selected regions in the coma ... [more ▼]

The multiobject spectrograph OPTOPUS, for use at the 3.6-m ESO telescope with the CCD detector, is described, and preliminary results of spectra obtained in December 1985 of selected regions in the coma of Halley's comet are presented. The instrument's 54 separately cabled optical fibers, whose input ends are located in the focal plane by connectors plugged into drilled starplates, enable light to be guided from freely distributed points in a 33 arcmin zone of the Cassegrain focal plane, to a common slit. The spectra show the presence of a very faint continuum, due to the scattering of solar line photons in the inner region of the coma, on which is superimposed the bright emission bands of molecules such as CN, C2, C3, and NH2. The spectra also indicate that the brightness decrease of molecular bands as a function of the projected radial distance is not the same for different molecules. 3-3 (PDF) ESO [less ▲]

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See detailOr bleu / Or noir
BALTHASAR, JEAN PIERRE; COLLIGNON, FABRICE; DE WIT, PIERRE et al

Article for general public (2005)

Au grand mécontentement général, le prix du pétrole augmente irrésistiblement. Malgré cela, notre société ne semble pas disposée à changer ses habitudes. [...] Ces mois de vacances ont été riches en ... [more ▼]

Au grand mécontentement général, le prix du pétrole augmente irrésistiblement. Malgré cela, notre société ne semble pas disposée à changer ses habitudes. [...] Ces mois de vacances ont été riches en catastrophes climatiques. Ainsi, en Afrique de l'Ouest, des milliers de personnes ont disparu suite à une longue famine consécutive à un ciel resté trop longtemps avare en précipitations. En Méditerranée occidentale, on ne compte plus les milliers d'hectares de forêt partis en fumée à cause de la sécheresse. Au même moment, l'Europe centrale et orientale est lasse de patauger dans l'eau. Les spécialistes qualifient ces inondations comme étant les plus graves qu'aient connues la Suisse et la Roumanie. L'Inde est également noyée alors que Taïwan se prépare à la tempête la plus violente de son histoire. Et après ces préliminaires dramatiques, voici Katrina qui sème chaos et désolation. [...] [less ▲]

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See detailL’oracle et le messager. Fiction de l’interview chez Mallarmé
Durand, Pascal ULg

in Lieux Littéraires / La Revue (2006), 9/10

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See detailUn oracle médical de Sarpédon à Séleucie du Calycadnos
Nissen, Cécile ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (2001), 14

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See detailOraison funèbre d'Alphonse Delescluse
Kurth, Godefroid ULg

Article for general public (1903)

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See detailOraison funèbre de Dominique Keiffer
Kurth, Godefroid ULg

in Revue de l'Instruction Publique en Belgique (1902), XLV

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See detailOral administration of the growth hormone (GH) secretagogue NN703 in adult patients with GH deficiency.
Svensson, J.; Monson, J. P.; Vetter, T. et al

in Clinical Endocrinology (2003), 58(5), 572-580

OBJECTIVE: Little is known of the usefulness of GH secretagogues (GHSs) in GH-deficient (GHD) adults. The objective of this study was to determine the number of responders to treatment with NN703 in GHD ... [more ▼]

OBJECTIVE: Little is known of the usefulness of GH secretagogues (GHSs) in GH-deficient (GHD) adults. The objective of this study was to determine the number of responders to treatment with NN703 in GHD adults. DESIGN: A multicentre, randomized, double-blind, and placebo-controlled study. PATIENTS: Ninety-seven GHD adults were included. MEASUREMENTS: The GH response before and after 1 week of oral treatment with NN703 (n = 83) or placebo (n = 14) was determined. The first and last dose of NN703 was 3 mg/kg, whereas the dose of NN703 was 1.5 mg/kg/day during the 6 days between the first and last doses. Furthermore, all 97 patients received 1 micro g/kg GH-releasing hormone (GHRH) 3 weeks after the last dose of NN703. RESULTS: Serum GH peak and area under curve (AUC) values after the first NN703 administration were greater than those after placebo administration (P < 0.05). However, after correction for the lower body mass index (BMI) in the NN703 group, this difference lost statistical significance. After 1 week of therapy, GH peak and AUC values were similar following the final doses of NN703 and placebo. Serum peak and AUC values of other anterior pituitary hormones were similar between the NN703 and placebo groups both after the first and last administration of study drug. Nine of the 83 patients (11%) responded with a serum peak GH concentration >or= 5 micro g/l after the first and/or last NN703 administration, whereas no patient responded after placebo administration. Serum IGF-I was unaffected by 1-week NN703 treatment, whereas serum IGFBP-3 was increased (P < 0.05 vs. placebo) also after correction for BMI. Mean serum peak GH concentration after GHRH administration was 2.1 micro g/l (+/-0.3, SEM), which was higher than that after the first NN703 administration (1.32 +/- 0.3, P < 0.05). CONCLUSION: NN703 administration was generally well tolerated. Eleven per cent of the GHD adult patients responded with a peak GH response >or= 5 micro g/l after the first and/or last administration of oral NN703. Although a majority of GHD adults will not respond to NN703, the present results suggest that oral NN703 treatment could be useful in some adult patients with moderately severe GHD. These patients may be identified by a test dose of GHS. [less ▲]

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See detailOral and inhaled corticosteroïds decreased eosinophilic airway inflammation and bronchial reactivity in ascaris suum-sensitized and challenged cats
Leemans, Jérôme ULg; Kirschvink, N.; Cambier, Carole ULg et al

in Proceedings: 26th Annual Symposium of the Veterinary and Comparative Respiratory Society (2008)

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See detailOral and intravenous ibandronate in the management of postmenopausal osteoporosis: A comprehensive review
Reginster, Jean-Yves ULg

in Current Pharmaceutical Design (2005), 11(28), 3711-3728

Convenient strategies are needed for postmenopausal osteoporosis management. Current oral bisphosphonates are effective and generally well tolerated, but are hampered by strict dosing requirements. Less ... [more ▼]

Convenient strategies are needed for postmenopausal osteoporosis management. Current oral bisphosphonates are effective and generally well tolerated, but are hampered by strict dosing requirements. Less frequent dosing schedules are expected to improve adherence to therapy and hence outcomes. Ibandronate is a potent, nitrogen-containing bisphosphonate in ongoing clinical development exploring its potential to be administered less frequently than at weekly intervals. Uniquely, ibandronate can be administered either orally or as an intravenous (i.v.) injection, with a between-dose interval of >2 months. In postmenopausal women, oral ibandronate, when administered either daily or intermittently, has demonstrated robust antifracture efficacy at the spine (62% [p=0.0001] and 50% [p=0.0006] risk reduction versus placebo), accompanied by significant increases in bone mineral density (BMD) at the spine and hip, and suppression of bone turnover markers. Studies of intermittent i.v. ibandronate injections in postmenopausal women have shown dose-related BMD gains and bone turnover marker suppression comparable to those obtained after a similar duration of treatment with the proven effective oral ibandronate regimen. Furthermore, in a trial conducted in patients with corticosteroid-induced osteoporosis, intermittent i.v. ibandronate injections reduced vertebral fracture risk by 62% versus an active control (p=0.043). In all these trials, the oral and i.v. ibandronate regimens were well tolerated. Ongoing, large multinational clinical trials are investigating two intermittent ibandronate regimens: once-monthly oral and intermittent i.v. injections. These simple ibandronate regimens are expected to provide the optimal combination of efficacy, tolerability and patient convenience, leading to improved treatment adherence and thus, enhanced outcomes in postmenopausal osteoporosis. [less ▲]

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