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Peer Reviewed
See detailNicholas Jose's 'Black Sheep'
Delrez, Marc ULg

Conference (2005, September 24)

Detailed reference viewed: 11 (1 ULg)
See detailNick translation : un outil pour la microscopie électronique
Thiry, Marc ULg

Scientific conference (1990)

Detailed reference viewed: 5 (0 ULg)
See detailNICOLAS A MICROS FERMES
Sacré, Robert ULg

Article for general public (1992)

Interview de Nicolas Dor , pt 1 : " Quand le silence est d'argent, la parole est d'or"

Detailed reference viewed: 5 (0 ULg)
See detailNicolas DOR , interview, pt 7 : La RTB au temps béni des captations
Sacré, Robert ULg

Article for general public (1993)

Detailed reference viewed: 11 (0 ULg)
See detailNicolas DOR , interview pt 5 - La vie dissolue de...Nicolas!
Sacré, Robert ULg

Article for general public (1991)

Detailed reference viewed: 8 (0 ULg)
See detailNicolas DOR - pt 3 : L'Epopée des Bob Shots
Sacré, Robert ULg

Article for general public (1992)

Detailed reference viewed: 7 (2 ULg)
See detailNicolas DOR, interview pt 4 - Le jazz et la radio sous l'occupation allemande
Sacré, Robert ULg

Article for general public (1992)

Detailed reference viewed: 18 (0 ULg)
See detailNicolas DOR, interview pt 6 : D'un Stardust de trop à N.Dor chanteur de jazz
Sacré, Robert ULg

Article for general public (1993)

Detailed reference viewed: 8 (0 ULg)
See detailNicolas Martella/ stratège des ressources humaines:note pédagogique
Robert, Jocelyne ULg

Learning material (2010)

Detailed reference viewed: 96 (3 ULg)
Full Text
Peer Reviewed
See detailNicolas Martella:stratège des ressources humaines-cas pédagogique
Robert, Jocelyne ULg

in Revue internationale de cas en gestion (2010), 8

Detailed reference viewed: 148 (14 ULg)
See detailNicolas Pietkin et Joseph Bastin
Droixhe, Daniel ULg

in Lejeune, R.; Stiennon, J. (Eds.) La Wallonie, le pays et les hommes : Lettres, arts-culture. Tome III (1979)

Detailed reference viewed: 41 (2 ULg)
See detailNicolas Sarkozy sur le yacht de Vincent Bolloré : étonnant, arrogant, indécent ?
Geuens, Geoffrey ULg

Article for general public (2007)

Detailed reference viewed: 49 (14 ULg)
See detailNicolas, à micros fermés pt 2
Sacré, Robert ULg

Article for general public (1992)

Interview de Nicoalas DOR, pt 2 : Jazz blanc...jazz noir

Detailed reference viewed: 8 (0 ULg)
See detailNicoletta CHERUBINI, Pierre nue, poème-légende des photographies de Nguyen Van Thong
Tilkin, Françoise ULg

in Catalogue de l'exposition Pierres nues (Liège, du 26 mai au 30 juin 1984) (1984)

Detailed reference viewed: 32 (4 ULg)
Full Text
Peer Reviewed
See detailNicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice.
Fernandes, Claudia A.; Fievez, Laurence ULg; Ucakar, Bernard et al

in American journal of physiology. Lung cellular and molecular physiology (2011), 300(3), 354-61

Neutrophils constitute the first line of host defense against invading microorganisms. Yet their removal from the inflammatory environment is fundamental for injury restraint and resolution of ... [more ▼]

Neutrophils constitute the first line of host defense against invading microorganisms. Yet their removal from the inflammatory environment is fundamental for injury restraint and resolution of inflammation. Nicotinamide, a component of vitamin B(3), is known to modulate cell survival. In this study, we assessed the influence of nicotinamide on neutrophil apoptosis, both in vitro and in vivo in a mouse model of endotoxin-induced lung inflammation. In vitro, nicotinamide promoted apoptosis of human blood neutrophils in a dose-dependent manner in the presence of the apoptosis inhibitors granulocyte colony-stimulating factor and granulocyte/macrophage colony-stimulating factor. The highest concentration of nicotinamide completely neutralized the pro-survival effect of granulocyte (macrophage) colony-stimulating factor. Nicotinamide proapoptotic effect was associated with enhanced caspase-3 activity. In addition, nicotinamide slightly reduced neutrophil chemotaxis in vitro. In vivo, pulmonary nicotinamide delivery decreased the levels of cellular and biochemical inflammation markers and increased the percentage of apoptotic neutrophils in bronchoalveolar lavages. Our findings suggest that nicotinamide is an apoptotic stimulus for neutrophils, thereby contributing to the resolution of neutrophilic inflammation in the lungs. [less ▲]

Detailed reference viewed: 25 (1 ULg)