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See detailNew biomarkers of Crohn's disease: serum biomarkers and development of diagnostic tools
Meuwis, Marie-Alice ULg; Fillet, Marianne ULg; Chapelle, Jean-Paul ULg et al

in Expert Review of Molecular Diagnostics (2008), 8

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See detailNew bisphosphonates for the treatment of osteoporosis : concerns and hopes
Reginster, Jean-Yves ULg

in Revue du Rhumatisme (English ed.) (1996), 63(7-8), 461-464

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See detailNew bounds on trilinear R-parity violation from lepton flavor violating observables
Dreiner, H. K.; Nickel, K.; Staub, F. et al

in Physical Review. D, Particles, Fields, Gravitation, and Cosmology (2012), 86

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See detailNew capabilities of the INCL4.6 model implemented into high-energy transport codes
Leray, S.; Boudard, A.; Braunn, B. et al

in Proceedings of Shielding Aspects of Accelerators, Targets and Irradiation Facilities 2011 (2013)

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See detailNew carbohydrate-active enzymes identified by screening two metagenomic libraries derived from the soil of a winter wheat field
Stroobants, Aurore ULg; Portetelle, Daniel ULg; Vandenbol, Micheline ULg

in Journal of Applied Microbiology (2014)

Aims Soils are rich, diversified environments where β-glucosidases abound because of their importance in organic matter degradation. The aim of this work was to discover new β-glucosidases by constructing ... [more ▼]

Aims Soils are rich, diversified environments where β-glucosidases abound because of their importance in organic matter degradation. The aim of this work was to discover new β-glucosidases by constructing two metagenomic DNA libraries from soil samples collected in winter and spring from a field of winter wheat. Methods and Results Both libraries were screened on esculin-supplemented medium so as to isolate candidates showing β-glucosidase activity. Candidate analysis revealed seven putative β-glycosidases and two putative glycosyltransferases, displaying 25 to 82% identity to known enzymes. The putative β-glycosidases belong to families GH1, GH3 and GH20 and the two putative glycosyltransferases, probably, to new families. In characterization tests performed on bacteria in suspension or spread on agar plates, some candidates appeared to hydrolyse several natural and synthetic substrates. These tests also highlighted interesting industrial characteristics, such as the activity of four β-glycosidases under alkaline conditions and the esculin-hydrolysing activity of a β-glucosidase candidate in the presence of glucose. Conclusions Seven putative β-glycosidases and two putative glycosyltransferases were found by functional screening of two metagenomic DNA libraries derived from agricultural soil. Significance and Impact of the Study This study has identified β-glycosidases and putative glycosyltransferases that have or may have interesting industrial characteristics. [less ▲]

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See detailA new case of consensual decision: collective movement in earthworms
Zirbes, Lara ULg; Deneubourg, Jean-Louis; Brostaux, Yves ULg et al

in Ethology (2010), 115

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See detailA new case of gravitational lensing
Surdej, Jean ULg; Magain, Pierre ULg; Swings, J.-P. et al

in Nature (1987), 329

The authors have begun a systematic search from ESO for gravitational lens systems in a selected sample of highly luminous quasars; M[SUB]V[/SUB] < -29.0. They give a brief description of their first ... [more ▼]

The authors have begun a systematic search from ESO for gravitational lens systems in a selected sample of highly luminous quasars; M[SUB]V[/SUB] < -29.0. They give a brief description of their first identified gravitational lens system UM673 = Q0142-100 = PHL3703. It consists of two images, A (m[SUB]R[/SUB] = 16.9) and B (m[SUB]R[/SUB] = 19.1), separated by 2.2 arc s at a redshift z[SUB]q[/SUB] = 2.719. The lensing galaxy (m[SUB]R[/SUB] â 19, Z[SUB]L[/SUB] â 0.49) has also been found. It lies very near the line connecting the two QSO images, â ¡0.8 arc s from the fainter one. A value M[SUB]0[/SUB] â 2.4×10[SUP]11[/SUP]M_sun; for the mass of the lensing galaxy and Deltat â 7 weeks for most likely travel-time difference between the two light paths to the QSO are found (assuming H[SUB]0[/SUB] = 75 km s[SUP]-1[/SUP]Mpc[SUP]-1[/SUP], q[SUB]0[/SUB] = 0). [less ▲]

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See detailNew catalysis for fast bulk ring-opening polymerization of lactide monomers
Degée, Philippe; Dubois, Philippe ULg; Jérôme, Robert ULg et al

in Macromolecular Symposia (1999), 144

The ring-opening polymerization of lactides has been studied in bulk using either 2-ethylhexanoic acid tin(II) salt, Sn(Oct)2, or aluminum triisopropoxide, Al(OiPr)3, as the initiator over a wide range of ... [more ▼]

The ring-opening polymerization of lactides has been studied in bulk using either 2-ethylhexanoic acid tin(II) salt, Sn(Oct)2, or aluminum triisopropoxide, Al(OiPr)3, as the initiator over a wide range of temperature and monomer-to-initiator molar ratio, A high increase in the bulk polymerization rate has been observed when the initiator was added with an equimolar amount of a Lewis base, such as triphenylphosphine and 4-picoline (C6H7N) added to Sn(Oct)2 and Al(OiPr)3, respectively Melt stable polylactides of high molecular weight and reasonably narrow molecular weight distribution have been accordingly prepared. The use of the Sn(Oct)2. equimolar combination has allowed for reaching an acceptable balance between propagation and depolymerization rates, so that the polymerization is fast enough to be performed through a continuous single-stage process in a twin-screw extruder A global activation mechanism is proposed and discussed by comparison with both investigated initiation systems. [less ▲]

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See detailA new CCD camera for the Echelec spectrograph.
Gilliotte, A.; Magain, Pierre ULg

in The Messenger (1987), 50

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See detailNEW CHALLENGES FOR 21ST CENTURY COMPETITION AUTHORITIES
Petit, Nicolas ULg

E-print/Working paper (2012)

This paper discusses challenges for competition authorities in the 21st century. Those challenges were identified on the basis of a statistical review of the articles published since January 2011 in five ... [more ▼]

This paper discusses challenges for competition authorities in the 21st century. Those challenges were identified on the basis of a statistical review of the articles published since January 2011 in five major antitrust law journals. The assumption underlying this literature review is that the topics that statistically attract the most the attention from contemporary antitrust scholars are those that will likely constitute the main challenges for 21st century competition authorities. [less ▲]

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See detailNew challenges for feature selection in data mining and knowledge discovery
Saeys, Yvan; Liu, Huan; Inza, Inaki et al

in Journal of Machine Learning Research (2008), 4

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See detailNew Chinese Migrants in Europe : The case of the Chinese community in Hungary
Florence, Eric ULg

in Nationalism & Ethnic Politics (2001), Vol. 7(Issue 1),

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See detailA New Cis Element Is Involved in the Her2 Gene Overexpression in Human Breast Cancer Cells
Grooteclaes, Madeleine; Vernimmen, Douglas; Plaza, S. et al

in Cancer Research (1999), 59(11), 2527-31

The HER2 proto-oncogene product is overexpressed in 30% of breast cancers, and this correlates with poor prognosis. Increased levels of HER2 mRNA in breast cancer cell lines result from increased gene ... [more ▼]

The HER2 proto-oncogene product is overexpressed in 30% of breast cancers, and this correlates with poor prognosis. Increased levels of HER2 mRNA in breast cancer cell lines result from increased gene transcription. We report the identification of a new 17-bp-long cis sequence located between positions -506 and -489 from the transcription start site. This sequence is recognized by a trans-activating factor that we tentatively named HER2 transcription factor (HTF). This factor, involved in the increased transcription of the HER2 gene in the BT-474 mammary tumor cells, has a molecular weight of about Mr 50,000. HTF can also bind, but with a lower affinity, to a related cis sequence present in the epidermal growth factor receptor promoter. Interestingly, the HTF binding activity is high in nuclear extracts from several mammary tumor cells overexpressing the HER2 gene. [less ▲]

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See detailNew Cold Plasma and DLC Surface Treatments for Medical Co-Cr-Mo and Ti-6Al-4V Prostheses
Matarazzo, Lucas; Gillet, Marie-Claire ULg; Forest, B et al

Poster (2006, September 27)

Recent studies indicate that the most important factor limiting the longevity of hip prostheses is the production of wear particles from the prosthetic components. We have studied the effect of two ... [more ▼]

Recent studies indicate that the most important factor limiting the longevity of hip prostheses is the production of wear particles from the prosthetic components. We have studied the effect of two surface treatment techniques on the Ti-6Al-4V alloy: ionic nitruration (cold plasma) and Diamond-like Coating (DLC). These two techniques create a layer of 7-8 μm in depth on the surface of the alloy, modifying its structure and hardening it considerably. Biocompatibility was analyzed using cellular culture to compare viability, proliferation (DNA quantification) and differentiation (ALP assay) of human osteoblast-like cells (MG 63) as well as cellular adhesion of human fibroblasts (WI 38) or osteoblasts, under SEM. [less ▲]

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See detailNew Colliding-Wind Massive Binaries
De Becker, Michaël ULg; Rauw, Grégor ULg

in Massive Stars in Interactive Binaries (2007)

We report on the recent discovery of two new massive binary systems: WR20a and CygOB2#8A. For both systems, we briefly present the orbital solutions and we discuss the strong phase-locked line profile ... [more ▼]

We report on the recent discovery of two new massive binary systems: WR20a and CygOB2#8A. For both systems, we briefly present the orbital solutions and we discuss the strong phase-locked line profile variability of the Halpha and HeII lambda 4686 lines for WR20a, and the HeII &; 4686 line in the case of CygOB2#8A. In both cases, we show that the profile variability reveals the signature of a wind interaction. The prospects for future high-energy observations are also discussed. [less ▲]

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See detailNew Combination Techniques in Dioxin Analysis
Focant, Jean-François ULg

in Lab Info (2008), 3

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See detailNew combinations in the Amblystegiaceae
Vanderpoorten, Alain ULg; Hedenäs, L.

in Journal of Bryology (2009), 31

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See detailA new combined bodian-luxol technique for staining unmyelinated axons in semithin, resin-embedded peripheral nerves: a comparison with electron microscopy.
Deprez, Manuel ULg; Ceuterick-de Groote, C.; Fumal, Arnaud ULg et al

in Acta Neuropathologica (1999), 98(4), 323-9

Quantitation of unmyelinated fibers (UF) in peripheral nerves has classically relied upon ultrastructural morphometry. Because this method is time-consuming, it is not typically performed in routine ... [more ▼]

Quantitation of unmyelinated fibers (UF) in peripheral nerves has classically relied upon ultrastructural morphometry. Because this method is time-consuming, it is not typically performed in routine analysis of nerve biopsies. We applied the Bodian-Luxol technique to detect unmyelinated axons by light microscopy on semithin sections from resin-embedded nerve tissue. Estimates were compared to ultrastructural counts. The staining appeared highly specific for axons. Excellent correlation was found between optic densities and the population of UF larger than 0.5 microm. The smallest profiles detected by light microscopy had a diameter close to 0.6 microm. This new technique is not a substitute for ultrastructural quantitative morphometry of UF, as very small unmyelinated axons, especially regenerating ones, can not be reliably visualized. However, it provides a valuable light microscopic method for evaluating axonal loss among UF. [less ▲]

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See detailA new computational method for nonlinear normal modes of nonconservative systems
Renson, Ludovic ULg; Kerschen, Gaëtan ULg

in Proceedings of the Euromech Colloquium n. 541 - New Advances in the Nonlinear Dynamics and Control of Composites for Smart Engineering Design (2013, June)

The concept of nonlinear normal modes (NNMs) was introduced with the aim of providing a rigorous generalization of normal modes to nonlinear systems. Initially, NNMs were defined as periodic solutions of ... [more ▼]

The concept of nonlinear normal modes (NNMs) was introduced with the aim of providing a rigorous generalization of normal modes to nonlinear systems. Initially, NNMs were defined as periodic solutions of the underlying conservative system, and continuation algorithms were recently exploited to compute them. To extend the concept of NNMs to nonconservative systems, Shaw and Pierre defined an NNM as a two-dimensional invariant manifold in the system’s phase space. This contribution presents a novel algorithm for solving the set of partial differential equations governing the manifold geometry numerically. The resolution strategy takes advantage of the hyperbolic nature of the equations to progressively solve them in annular regions. Each region is defined by two different iso-energy curves and equations are discretized using a specific finite element technique. The proposed strategy also offers the opportunity to estimate the frequency-energy dependence of the mode without using time integration. The algorithm is applied to both conservative and nonconservative systems. [less ▲]

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