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See detailInnovative methods for the determination of the taxonomic origin of processed animal proteins in feed.
Veys, Pascal; Ngo Njembe, M.; Lecrenier, Marie-Caroline ULg et al

Poster (2015, November)

The use of animal by-products in feed depends on their nature defined by the type of tissue or body parts and the species of origin. Currently, the detection of unauthorised processed animal proteins ... [more ▼]

The use of animal by-products in feed depends on their nature defined by the type of tissue or body parts and the species of origin. Currently, the detection of unauthorised processed animal proteins (PAPs) is based on light microscopy and PCR methods. Light microscopy identifies structures on the basis of their morphology and enables identification of particles (such as bones, cartilages, muscle fibres,…) while PCR is able to detect and identify the presence of specific animal DNA in feed. Nevertheless, for some scenarios, even combined, these methods do not succeed in determining the taxonomic origin of the PAPs. A typical example is that of an aquafeed containing authorised porcine PAP together with dairy products: the analysis will conclude of the potential presence of ruminant PAP. Therefore, there is a need for developing methods allowing a taxonomic characterisation of visual structures such as bones fragments and muscle fibres. For the characterisation of bones, NIRM has yet demonstrated its potential. However the limitation of NIRM is when the presence of bones is reduced or absent. This study investigated the potential of NIRM for the determination of the taxonomic origin of muscle fibres. The NIRM was experimented on 2 porcine PAPs vs. 6 ruminant PAPs and 7 fishmeals all of industrial origin. Results showed that NIRM allows differentiating muscle fibres from different taxonomic origins: fish, ruminant and pig. In addition to this taxonomic classification, results also reveal differences inside taxonomic clusters of PAPs (e.g among different ruminant PAPs and porcine PAPs). The results obtained on this type of meals are promising and offer new perspectives. Tests on adulterated feeds need to be performed by NIRM prior to validation. [less ▲]

Detailed reference viewed: 22 (4 ULg)
See detailInnovative multilayered nanofibers for wound dressing application
Croisier, Florence ULg; Detrembleur, Christophe ULg; Jérôme, Christine ULg

Poster (2012, April 18)

Chitosan is a natural polymer derived from the chitin of crustacean or mushroom shells, that intrinsically presents haemostatic, mucoadhesive, antimicrobial and immunostimulant properties. This ... [more ▼]

Chitosan is a natural polymer derived from the chitin of crustacean or mushroom shells, that intrinsically presents haemostatic, mucoadhesive, antimicrobial and immunostimulant properties. This polysaccharide has shown a great potential for biomedical and pharmaceutical applications, on account of its remarkable compatibility with physiological medium. Besides, it is degraded in a physiological environment into non-toxic products, which make chitosan an outstanding candidate for short- to medium-term applications. In this respect, nanometric fibers are highly interesting as their assembly mimics the skin extracellular matrix structure. Such nanofibrous materials can be prepared by electrospinning (ESP). This technique uses a high voltage to create an electrically charged jet of polymer solution or melt which leads to fibers formation. Depending on the polymer characteristics (a.o. molecular weight, solution viscosity and conductivity) and processing conditions (electric potential, distance between syringe-capillary and collection plate, concentration, flow rate), polymer fibers ranging from nanometers to a few microns in diameter can be obtained and subsequently used as potential scaffolds, a.o. to form a temporary, artificial extracellular matrix. In the present study, electrospinning technique was combined with layer-by-layer deposition method (LBL) - a well-known method for surface coating, based on electrostatic interactions - in order to prepare multilayered chitosan-based nanofibers. The antibacterial properties of the obtained material were then assessed, and the presence of a multilayered deposit was confirmed by several techniques. (Future) possibilities for valorization: These multilayered chitosan-based nanofibers present great prospects for the preparation of new biomedical scaffolds - such as wound dressings that could improve skin regeneration. [less ▲]

Detailed reference viewed: 79 (5 ULg)
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See detailAn innovative non-animal chitosan hydrogel is able to restore the rheology of osteoarthritis synovial fluid ex vivo
Henrotin, Yves ULg; Rocasalbas, Guillem; Chausson, Mickaël et al

Poster (2016, September)

Detailed reference viewed: 22 (0 ULg)
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See detailInnovative polyelectrolytes/poly(ionic liquid)s for energy and environment
Ajjan, Fátima N.; Ambrogi, Martina; Tiruye, Girum Ayalneh et al

in Polymer International (in press)

This manuscript presents the work carried out within the European Project RENAISSANCE-ITN, which was dedicated to the development of innovative polyelectrolytes for energy and environmental applications ... [more ▼]

This manuscript presents the work carried out within the European Project RENAISSANCE-ITN, which was dedicated to the development of innovative polyelectrolytes for energy and environmental applications. Within the project different types of innovative polyelectrolytes were synthesized such as poly(ionic liquid)s coming from renewable or natural ions, thiazolium cations, cathechol functionalities or from a new generation of cheap deep-eutectic monomers. Further, macromolecular architectures such as new poly(ionic liquid) block copolymers and new (semi)conducting polymer/polyelectrolyte complexes were also developed. As the final goal, the application of these innovative polymers in energy and environment was investigated. Important advances in energy storage technologies included the development of new carbonaceous materials, new lignin/conducting polymer biopolymer electrodes, new iongels and single-ion conducting polymer electrolytes for supercapacitors and batteries and new poly(ionic liquid) binders for batteries. On the other hand, the use of the innovative polyelectrolytes into sustainable environmental technologies led to the development of new liquid and dry water, new materials for water cleaning technologies such as floculants, oil absorbers, new recyclable organocatalysts platform and multifunctional polymer coatings with antifouling and antimicrobial properties. All in all this article demonstrates the potential of the poly(ionic liquid)s for high-value applications in Energy & Enviromental areas. [less ▲]

Detailed reference viewed: 45 (8 ULg)
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See detailAn innovative procedure for smoothing parameter selection
Frasso, Gianluca ULg; Eilers, Paul H.C.

in Proceedings of 46th scientific meeting of the Italian Statistical Society (2012, June)

Smoothing with penalized splines calls for an automatic method to select the size of the penalty parameter λ. We propose a not well known smoothing parameter selection procedure: the L-curve method. AIC ... [more ▼]

Smoothing with penalized splines calls for an automatic method to select the size of the penalty parameter λ. We propose a not well known smoothing parameter selection procedure: the L-curve method. AIC and (generalized) cross validation represent the most common choices in this kind of problems even if they indicate light smoothing when the data represent a smooth trend plus correlated noise. In those cases the L-curve is a computationally efficient alternative and robust alternative. [less ▲]

Detailed reference viewed: 4 (0 ULg)
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See detailInnovative Proteomics for the Discovery of Systemically Accessible Cancer Biomarkers Suitable for Imaging and Targeted Therapies
Turtoi, Andrei ULg; De Pauw, Edwin ULg; Castronovo, Vincenzo ULg

in American Journal of Pathology (2011), 178(1), 12-18

The discovery of biomarkers that are readily accessible through the circulating blood and are selectively overexpressed in pathological tissues has become a major research objective, particularly in the ... [more ▼]

The discovery of biomarkers that are readily accessible through the circulating blood and are selectively overexpressed in pathological tissues has become a major research objective, particularly in the field of oncology. Indisputably, this group of molecules has a high potential to serve as an innovative tool for effective imaging and targeted cancer therapy approaches. In this attractive therapeutic concept, specific cancer proteins are reached by intravenously administered ligands that are coupled to cytotoxic drugs. Such compounds are able to induce cancer destruction while sparing normal tissues. Owing to the performance of mass spectrometry technology, current high-throughput proteomic analysis allows for the identification of a high number of proteins that are differentially expressed in the cancerous tissues. However, such approaches provide no information regarding the effective accessibility of the biomarkers and, therefore, the possibility for these discovered proteins to be targeted. To bypass this major limitation, which clearly slows the discovery of such biomarkers, innovative methodological strategies have been developed to enrich the clinical specimens before the mass spectrometry analysis. The focus is laid on the group of proteins that are necessarily located either at the exterior face of the plasma membrane or in the extracellular matrix. The present review addresses the current technologies meant for the discovery and analysis of accessible antigens from clinically relevant samples. [less ▲]

Detailed reference viewed: 50 (14 ULg)
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See detailInnovative semiconducting oxide materials reducing the energy footprint of buildings
Dewalque, Jennifer ULg; Maho, Anthony ULg; Spronck, Gilles ULg et al

Conference (2015, October 26)

In the current energy context, many efforts are devoted to the reduction of the energy footprint of buildings. To meet this challenge, the LCIS-GREENMAT laboratory developes a front edge research in the ... [more ▼]

In the current energy context, many efforts are devoted to the reduction of the energy footprint of buildings. To meet this challenge, the LCIS-GREENMAT laboratory developes a front edge research in the field of advanced materials associated to energy and environment, including structured materials for dye-sensitized solar cells (DSSCs) and electrochromic coatings. DSSCs have been reported by O’Regan and Grätzel in the early nineties as a very promising alternative to conventional photovoltaic silicon devices. Main benefits of these cells are their low cost as well as their mild manufacturing process. In most of the specific literature, DSSCs are made of TiO2 films prepared by doctor-blade or screen-printing of anatase nanoparticles paste. However, due to the random organization of the nanoparticles, pore accessibility by the dye and electrolyte could be incomplete. Moreover, some anatase crystallites could suffer from a lack of connectivity, leading to electron transfer issues. The strategy adopted by our group to improve photovoltaic efficiencies involves a templating-assisted process to prepare highly porous layers with well-ordered and accessible pores as well as improved crystallites connectivity. This talk especially focuses on the templating-assisted synthesis of TiO2 and ZnO semiconducting layers used as photoelectrode in DSSCs. Due to the surface area improvement as well as the perfect control of the pore organization and the pore size, the templating strategy is an effective solution to maximize the adsorption of active dye and the electrolyte infiltration inside the porous network. Besides, in the last few years, there has been increasing interest in electrochromic glazing due to its potential use as an energy-efficient component for buildings, as it could reduce considerably their CO2 emission by decreasing their energy consumption up to 30%. The crucial issues of such devices are the durability, the coloration efficiency and the reversibility upon coloration and bleaching of the electrochromic layers. In order to improve the performances of those electrochromic films, we have investigated a surfactant-assisted deposition process for WO3 layer and the insertion of lithium in the NiO layer. All films have been deposited on FTO glass substrates by ultrasonic spray pyrolysis (USP), which is a low-cost alternative to industrial vacuum processes for manufacturing high quality thin films. The presence of lithium ions in nickel oxide films has shown improved coloration efficiency compared to the undoped films. The higher active surface of surfactant-assisted tungsten oxide films has led to higher reversibility and coloration contrast. [less ▲]

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See detailInnovative smart sensors to enhance eco-efficiency of a continuous (steel) production line
Saint-Mard, Michel; Stoukatch, Serguei ULg; Schischke, Karsten et al

in Proc. Conf. of the AMA Association for Sensor Technology (2013, May 15)

The paper aims to demonstrate the benefits for a global approach that allows to define new research directions, new potential industrial markets, and increasing interest from potential users. Combining ... [more ▼]

The paper aims to demonstrate the benefits for a global approach that allows to define new research directions, new potential industrial markets, and increasing interest from potential users. Combining performance, economic and environmental criteria in a joint assessment approach for the target applications of sensor systems, facilitates significantly the communication between service provider and user. The environmental assessment approach for sensor systems will be available as a beta-version online tool tentatively from July 2013 onwards. Interested SMEs are invited to get involved as the LCA to go consortium will provide also a comprehensive mentoring for SMEs [less ▲]

Detailed reference viewed: 55 (5 ULg)
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See detailAn innovative solution to improve the seismic robustness of reinforced concrete frames
Degée, Hervé ULg; Plumier, André ULg

in Proceedings of the 14ECEE Conference (2010)

Detailed reference viewed: 61 (4 ULg)
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See detailInnovative strategies for the control of apple scab (Venturia inaequalis [Cke.] Wint.) in organic apple production
Jamar, Laurent ULg

Doctoral thesis (2011)

The aim of this thesis, conducted over six growing seasons (2003-2008), is to define new measures for reducing the use of fungicides and in particular, copper fungicides, for the control of apple scab (V ... [more ▼]

The aim of this thesis, conducted over six growing seasons (2003-2008), is to define new measures for reducing the use of fungicides and in particular, copper fungicides, for the control of apple scab (V. inaequalis) in organic apple production. Special emphasis is put on primary scab infection control during spring season. An original approach is proposed for defining a specific spray timing involving spraying during the infection processes, especially before fungal penetration, determined by the RIMpro software warning system. This ‘during-infection’ spray strategy allows reducing from 30 to 50% the amount of fungicide usually used for effective apple scab control, on high scab-susceptible cultivars. The field study shows that six alternative products (e.g., potassium bicarbonate and lime sulphur), among 60 products tested, have the potential to reduce copper use. However, copper use, even with low doses, seems to be still necessary in presence of scab-susceptible cultivars. The results obtained in these experiments could not be attributed to the specific technical performances of the tunnel sprayer used, which however, offer valuable environmental benefits. On the basis of the present study, the organic management system seems a good farming approach for maintaining soil quality with regard to biological indicators. This work shows and draws attention to the fact that (i) planting cultivars with polygenic scab-resistance traits, (ii) increasing emphasis on sanitation practices aimed at reducing initial inoculum in autumn, and (iii) applying an accurate spray strategy in spring, as defined in the present study, are the three most promising approaches for substantial further reductions in protection products fully compliant with international organic crop production standards. [less ▲]

Detailed reference viewed: 507 (12 ULg)
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See detailInnovative Surface Plasmon Resonance biosensing architectures
Desfours, Caroline; Piron, Pierre ULg; Habraken, Serge ULg et al

Conference (2012, December 11)

Surface Plasmons Resonance (SPR) architectures involving multi-wavelength interrogation are an attractive alternative for droplet biosensing. We present our results for in situ measurements of biological ... [more ▼]

Surface Plasmons Resonance (SPR) architectures involving multi-wavelength interrogation are an attractive alternative for droplet biosensing. We present our results for in situ measurements of biological molecules with a two-wavelength sensor and a SPR Coupler-Disperser spectroscopic sensor. [less ▲]

Detailed reference viewed: 39 (5 ULg)
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See detailInnovative Surface Plasmon Resonance biosensing architectures
desfours, Caroline; Hastanin, Juriy ULg; Drucbert, Anne-Sophie et al

in International Conference on Fibre Optics and Photonics (2012, December)

Surface Plasmons Resonance (SPR) architectures involving multi-wavelength interrogation are an attractive alternative for droplet biosensing. We present our results for in situ measurements of biological ... [more ▼]

Surface Plasmons Resonance (SPR) architectures involving multi-wavelength interrogation are an attractive alternative for droplet biosensing. We present our results for in situ measurements of biological molecules with a two-wavelength sensor and a SPR Coupler- Disperser spectroscopic sensor. [less ▲]

Detailed reference viewed: 25 (7 ULg)
See detailInnovative utilization of the Lactoperoxidase System against apple’s postharvest diseases
Bafort, Françoise ULg; Jijakli, Haissam ULg; Perraudin, Jean-Paul

Conference (2012, September 21)

Detailed reference viewed: 41 (5 ULg)
See detailInnovatives techniques in implant dentistry
LAMBERT, France ULg

Scientific conference (2008)

Detailed reference viewed: 12 (0 ULg)