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See detailNew Studies and Progress in Ne IV, V and VI Term Analysis
Bastin, Thierry ULg; Biémont, Emile ULg; Dumont, Paul-Dominique ULg et al

in Proceedings of the 5th International Colloquium on Atomic Spectra and Oscillator Strengths for Astrophysical and Laboratory Plasmas (1996)

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See detailA new subspace-based approach to identify nonlinear mechanical structures in the frequency domain
Noël, Jean-Philippe ULg; Kerschen, Gaëtan ULg

in Proceedings of the 16th IFAC Symposium on System Identification (2012, July)

This paper introduces a new frequency-domain subspace-based method for the identification of nonlinear mechanical systems. The technique exploits frequency data and interprets nonlinearities as feedback ... [more ▼]

This paper introduces a new frequency-domain subspace-based method for the identification of nonlinear mechanical systems. The technique exploits frequency data and interprets nonlinearities as feedback forces exciting the underlying linear system. It is demonstrated using two academic examples, a Duffing oscillator and a five degree-of-freedom system comprising two nonlinearities. [less ▲]

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See detailNew substituted aryl esters and aryl amides of 3,4-dihydro-2H-1,2,4- benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors
Dintilhac, Gaëlle ULg; Arslan, Deniz ULg; Dilly, Sébastien ULg et al

in MedChemComm (2011), 2

AMPA receptor potentiators belonging to 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides have been found to be of great interest as cognitive enhancers. Previous structure–activity relationships have ... [more ▼]

AMPA receptor potentiators belonging to 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides have been found to be of great interest as cognitive enhancers. Previous structure–activity relationships have demonstrated the importance for activity of the nature of the substituent at the 7-position of the heterocycle. This work aims to explore the impact on AMPA potentiation of the introduction of different aryl and aralkyl ester or aryl amide groups at the 7-position. The new synthesized compounds were evaluated as AMPA receptor potentiators by examining their effect on rat brain primary cell cultures on AMPA-evoked membrane depolarisation using fluorescent membrane potential dyes and on imaging-based plate reader. The most potent compound of this series was 2-methylphenyl 4-methyl- 3,4-dihydro-2H-1,2,4-benzothiadiazine-7-carboxylate 1,1-dioxide 16c which provoked a strong potentiation of AMPA current with a potency close to that reported for the best reference compounds of the benzothiadiazine class (i.e cyclothiazide). This work also revealed that only the ortho-substitution of the phenyl group of 1,2,4-benzothiadiazine-7-carboxylate esters provided potent AMPA receptor potentiators opening the way to further chemical exploration. [less ▲]

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See detailA new substrate cycle in plants. Evidence for a high glucose-phosphate-to-glucose turnover from in vivo steady-state and pulse-labeling experiments with [13C]glucose and [14C]glucose.
Alonso, Ana Paula; Vigeolas, Hélène ULg; Raymond, Philippe et al

in Plant Physiology (2005), 138(4), 2220-32

Substrate (futile) cycling involving carbohydrate turnover has been widely reported in plant tissues, although its extent, mechanisms, and functions are not well known. In this study, two complementary ... [more ▼]

Substrate (futile) cycling involving carbohydrate turnover has been widely reported in plant tissues, although its extent, mechanisms, and functions are not well known. In this study, two complementary approaches, short and steady-state labeling experiments, were used to analyze glucose metabolism in maize (Zea mays) root tips. Unidirectional rates of synthesis for storage compounds (starch, Suc, and cell wall polysaccharides) were determined by short labeling experiments using [U-14C]glucose and compared with net synthesis fluxes to determine the rate of glucose production from these storage compounds. Steady-state labeling with [1-(13)C]glucose and [U-13C]glucose showed that the redistribution of label between carbon C-1 and C-6 in glucose is close to that in cytosolic hexose-P. These results indicate a high resynthesis flux of glucose from hexose-P that is not accounted for by glucose recycling from storage compounds, thus suggesting the occurrence of a direct glucose-P-to-glucose conversion. An enzyme assay confirmed the presence of substantial glucose-6-phosphatase activity in maize root tips. This new glucose-P-to-glucose cycle was shown to consume around 40% of the ATP generated in the cell, whereas Suc cycling consumes at most 3% to 6% of the ATP produced. The rate of glucose-P cycling differs by a factor of 3 between a maize W22 line and the hybrid maize cv Dea, and is significantly decreased by a carbohydrate starvation pretreatment. [less ▲]

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See detailNew sulfonylurea torasemide derivatives as potential antihypertensive drugs
Masereel, B.; Pirotte, Bernard ULg; Schynts, M. et al

Poster (1990, September)

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See detailNew sulfonylurea torasemide derivatives as potential antihypertensive drugs
Masereel, B.; Pirotte, Bernard ULg; Schynts, M. et al

in Journal de Pharmacie de Belgique (1990), 45

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See detailA new super-element for estimating the collision resistance of an inclined ship side
Buldgen, Loïc ULg; Le Sourne, Hervé; Rigo, Philippe ULg

in Advancements in Marine Structures : Proceedings of MARSTRUCT 2013, the 4th International Conference on Marine Structures, Espoo, Finland, 25th – 27th March 2013 (2013)

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See detailNew Surface-Enhanced Raman Scattering Platforms: Composite Calcium Carbonate Microspheres Coated with Astralen and Silver Nanoparticles
Stetciura, Inna Y.; Markin, Alexey V.; Ponomarev, Andrei N. et al

in Langmuir (2013), 29

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See detailNew surgical technique for treatment of stress urinary incontinence TVT-ABBREVO: From development to clinical experience
Waltregny, David ULg; de Leval, Jean ULg

in Surgical Technology International (2012), XXII(pii), 2223

Tension-free suburethral tapes have revolutionized the surgical treatment of female stress urinary incontinence (SUI). These tapes are inserted by way of a retropubic or transobturator route. The inside ... [more ▼]

Tension-free suburethral tapes have revolutionized the surgical treatment of female stress urinary incontinence (SUI). These tapes are inserted by way of a retropubic or transobturator route. The inside-out tension-free vaginal tape transobturator approach, or TVT-Obturator system (TVT-O®, Ethicon Women's Health and Urology, Somerville, NJ), was developed ten years ago with the aim of minimizing the risk of urinary tract injuries associated with retropubic and outside-in transobturator tapes while reproducibly ensuring minimal tissue dissection. Cadaveric studies have shown that the anatomical trajectory of the TVT-O tape is strictly perineal and courses away from neighboring obturator and pudendal neurovascular structures. Several meta-analyses have shown similar SUI cure rates after retropubic and transobturator tape procedures. Yet, the transobturator route may be associated with less voiding dysfunction, blood loss, bladder perforation, and shorter operating time. The original TVT-O procedure was modified with the aim of reducing the incidence of postoperative groin pain as well as the rather theoretical risk of obturator nerve injury. This modified procedure, named TVT-ABBREVO® (Ethicon Women's Health and Urology, Somerville, NJ), utilizes a shortened, 12-cm-long polypropylene tape. In addition, perforation of the obturator membrane with the scissors and guide is avoided in order to reduce the depth of lateral dissection, and consequently, to maximize securing of the tape within the obturator muscular/aponeurotic structures. In a comparative anatomical study, it was indeed observed that the shorter tape traversed less muscular structures (with no or only a minimal amount of tape lying in the adductor muscles) than its original counterpart, while still consistently anchoring in the obturator membrane at a similarly safe distance from the obturator canal. In a single-center randomized clinical trial, after a 3-year minimum follow-up, the modified TVT-O procedure with a shorter tape and reduced dissection was found to be as safe and efficient as the primal procedure for treating female SUI, with less severe and frequent groin pain in the immediate postoperative period. [less ▲]

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See detailNew surgical technique for treatment of stress urinary incontinence TVT-Obturator: New developments and results
de Leval, Jean ULg; Waltregny, David ULg

in Surgical Technology International (2005), 14

A new surgical technique, the inside-out transobturator tension-free urethral suspension (TVT-Obturator), has been developed for treatment of women suffering from stress urinary incontinence (SUI). This ... [more ▼]

A new surgical technique, the inside-out transobturator tension-free urethral suspension (TVT-Obturator), has been developed for treatment of women suffering from stress urinary incontinence (SUI). This simple procedure uses specifically designed surgical instruments to allow the accurate passage of a synthetic tape from underneath the urethra, through the obturator foramens, toward the thigh folds, with the tape being positioned without tension under the junction between mid and distal urethra. Cadaver dissection studies have demonstrated that the anatomical trajectory of the tape in tissues is strictly perineal and consistently coursed away from neighboring neurovascular structures, including the obturator, femoral, and saphenous nerves and vessels, as well as the pudendal nerve. Consequently, as opposed to retropubic sling systems, no perioperative cystoscopy is required because the TVT-O tape does not enter the pelvic region at any time during the procedure. These anatomical data, which suggest the TVT-O technique is safe, have been corroborated by initial clinical experience. Our feasibility and ongoing efficacy studies have shown that TVT-O is associated with a low incidence of perioperative and postoperative complications. In our current series of more than 500 consecutive patients treated with TVT-O, no injury to the bladder or urethra was encountered and no perineal or obturator hematoma, heavy bleeding, or neurological complication was observed. Medium-term results have suggested that TVT-O is as efficient as retropubic tension-free slings for treatment of female SUI, with +/-90% complete cure rates after one-year follow up. [less ▲]

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See detailNew system for complexation of uranyl ions from liquid wastes of low-level activity: Polypyrrole doped with complexing polyanions
Leroy, Danielle ULg; Martinot, Lucien; De Becker, Michaël ULg et al

in Journal of Applied Polymer Science (2000), 77(6), 1230-1239

Polymer composites consisting of polypyrrole doped by uranyl complexing polyanions [i.e., poly(2-acrylamidoglycolic acid) and poly(2-acrylamido-2-methyl-1-propanesulfonic acid)] were electrochemically ... [more ▼]

Polymer composites consisting of polypyrrole doped by uranyl complexing polyanions [i.e., poly(2-acrylamidoglycolic acid) and poly(2-acrylamido-2-methyl-1-propanesulfonic acid)] were electrochemically synthesized. Bulk material and thin layers strongly adhering to inert supporting electrodes were prepared. These composites were used to precipitate uranyl ions from simulated radioactive wastes. Among different experimental techniques used for the analysis of uranium immobilized in the composites, the Rutherford backscattering of cu particles proved efficient in thin layers. Leaching tests confirmed the persistence of the uranium complexation in the solid composites. [less ▲]

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See detailA new system for the controlled radical polymerization of vinyl acetate
Debuigne, Antoine ULg; Detrembleur, Christophe ULg; Bryaskova, Rayna ULg et al

in Polymer Preprints (2005), 46(2), 313-314

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See detailA new system for the controlled radical polymerization of vinyl acetate
Detrembleur, Christophe ULg

Conference (2005, August 28)

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See detailNew systems for asymmetric dihydroxylation of olefins
Colaux, Catherine ULg

Conference (1999, December 03)

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See detailNew technique for hydaulic penile prosthesis insertion and corporeal closure
Andrianne, Robert ULg

in Journal of Sexual Medicine (2004), 1 Suppl 1

An original technique of insertion and corporotomy closure on the level proximal is described. Proximal angle of corporotomy is closed on the pipe of the hydraulic cylinder by a point of vicryl which was ... [more ▼]

An original technique of insertion and corporotomy closure on the level proximal is described. Proximal angle of corporotomy is closed on the pipe of the hydraulic cylinder by a point of vicryl which was installed before the device implantation. This simple technique allows correct installation of proximal extremity of the prosthesis in the tail of the cavernous body and avoids damage and perforation to the prothesis. Disclosure: Was this work supported by industry? No. [less ▲]

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See detailA new technique of stereotactic permanent breast seed implantation
Jansen, Nicolas ULg; Nickers, Philippe ULg

in Radiotherapy & Oncology (2006, October), 81(Suppl. 1), 249-250

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See detailA new technique to prevent vocal folds scars
FINCK, Camille ULg

in Laryngoscope (2005), 15

Detailed reference viewed: 8 (0 ULg)