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See detailNew spillway at the Esch-sur-Sûre dam in Luxembourg
Lazaro, Philippe; Toussin, Guy; Didier, Gilles et al

in Wasserwirtschaft (2007), 10

The 50-m high arch dam of Esch-sur-Sûre, built on the river Sûre between 1956 and 1957, is located 1.2 km upstream of the town of esch-sur-Sûre in the north west of Luxembourg. As the dam is not equipped ... [more ▼]

The 50-m high arch dam of Esch-sur-Sûre, built on the river Sûre between 1956 and 1957, is located 1.2 km upstream of the town of esch-sur-Sûre in the north west of Luxembourg. As the dam is not equipped with a surface spillway, the construction of a new one is considered necessary. The new spillway design with a discharge capacity of 400 m³/s consists in building two labyrinth weirs discharging into a spillway tunnel passing under the left dam abutment. [less ▲]

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See detailA new spore assemblage to correlate between the Breconian (British Isles) and the Gedinnian (Belgium)
Richardson, JB; Streel, Maurice ULg; Hassan, A et al

in Annales de la Société Géologique de Belgique (1982), 105

Detailed reference viewed: 17 (1 ULg)
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See detailNew Standard Formulation for Neonatal Parenteral Nutrition.
SENTERRE, Thibault ULg

in Congress of the Portuguese Neonatal Society (2012, May)

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See detailA New State of Turbulence: Elasto-Inertial Turbulence
Dubief, Yves; Samanta, Devranjan; Holzner, Markus et al

Conference (2012, November 20)

The elasticity of polymer solutions is found to generate a new state of turbulence, elasto-inertial turbulence (EIT), characterized by an interplay between elastic and flow instabilities. Experiments and ... [more ▼]

The elasticity of polymer solutions is found to generate a new state of turbulence, elasto-inertial turbulence (EIT), characterized by an interplay between elastic and flow instabilities. Experiments and direct numerical simulations (DNS) in pipe and channel flows demonstrate the emergence of EIT at Reynolds numbers much lower than the critical Reynolds number for transition to turbulence in Newtonian flows. EIT causes the friction factor to deviate from the laminar solution and subsequently transition to the maximum drag reduction asymptote around Re=1800. EIT is a self-sustained mechanism that arises from the interactions between fluctuations of extensional viscosity, velocity and pressure. The polymer solution elasticity controls the growth of flow instability, resulting in transitional-like flows at high Reynolds numbers. The existence of EIT is not limited to pipe, channel or boundary layer flows, and evidence of EIT will be discussed in other flows, including natural convection using DNS. [less ▲]

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See detailA new statistical method for evaluating long-term analytical performance of laboratories applied to an external quality assessment scheme for flow cytometry.
Coucke, Wim; Van Blerk, Marjan; Libeer, Jean*-Claude et al

in Clinical Chemistry & Laboratory Medicine (2010), 48(5), 645-50

BACKGROUND: The Belgian External Quality Assessment Scheme for Flow Cytometry evaluates the long-term analytical performance of participating laboratories by calculating a regression line between the ... [more ▼]

BACKGROUND: The Belgian External Quality Assessment Scheme for Flow Cytometry evaluates the long-term analytical performance of participating laboratories by calculating a regression line between the target and reported values of each parameter for each laboratory during the past 3 years. This study aims to develop a method to find laboratories with aberrant variability or bias using robust techniques and to obtain robust estimates of the variability. METHODS: A method is proposed to find outliers with respect to the individual regression line, followed by a step to find regression lines with excessive variability and finally a step to find regression lines with high bias. RESULTS: The model was applied to the results obtained by 52 laboratories for CD4%. From the 1340 data points, 35 were determined to be regression outliers. The second step revealed one regression line with excessive variability; the third step detected three regression lines with exceeding bias. CONCLUSIONS: The methodology allows assessment of the long-term performance of laboratories, taking into account samples with different target values. Outliers in the first step indicate accidental mistakes, outliers in the second and third step point to high analytical variability or bias. [less ▲]

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See detailA new statistical method for the automated detection of peaks in UV-DAD chromatograms of a sample mixture
Debrus, Benjamin ULg; Lebrun, Pierre ULg; Ceccato, Attilio ULg et al

in Talanta (2009), 79

One of the major issues within the context of the fully automated development of chromatographic methods consists of the automated detection and identification of peaks coming from complex samples such as ... [more ▼]

One of the major issues within the context of the fully automated development of chromatographic methods consists of the automated detection and identification of peaks coming from complex samples such as multi-component pharmaceutical formulations or stability studies of these formulations. The same problem can also occur with plant materials or biological matrices. This step is thus critical and time-consuming, especially when a Design of Experiments (DOE) approach is used to generate chromatograms. The use of DOE will often maximize the changes of the analytical conditions in order to explore an experimental domain. Unfortunately, this generally provides very different and “unpredictable” chromatograms which can be difficult to interpret, thus complicating peak detection and peak tracking (i.e. matching peaks among all the chromatograms). In this context, Independent Components Analysis (ICA), a new statistically based signal processing methods was investigated to solve this problem. The ICA principle assumes that the observed signal is the resultant of several phenomena (known as sources) and that all these sources are statistically independent. Under those assumptions, ICA is able to recover the sources which will have a high probability of representing the constitutive components of a chromatogram. In the present study, ICA was successfully applied for the first time to HPLC–UVDAD chromatograms and it was shown that ICA allows differentiation of noise and artifact components from those of interest by applying clustering methods based on high-order statistics computed on these components. Furthermore, on the basis of the described numerical strategy, itwas also possible to reconstruct a cleaned chromatogram with minimum influence of noise and baseline artifacts. This can present a significant advance towards the objective of providing helpful tools for the automated development of liquid chromatography (LC) methods. It seems that analytical investigations could be shortened when using this type of methodologies. [less ▲]

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See detailNew strategies and new impact of cancer imaging
Couturier, Olivier; Hustinx, Roland ULg; Chatal, Jean-François

in SERVIER, Jacques (Ed.) Cancer : recent evidence, innovative strategies, future promises (2004)

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See detailNew strategies to prepare melt processable polymer-grafted gold nanoparticles
Alexandre, Michaël ULg; Abetz, Volker; Boschetti-de-Fierro, A. et al

Poster (2008, November 28)

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See detailNew strategy for comprehensive analysis of polybrominated diphenyl ethers, polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls by gas chromatography coupled with mass spectrometry
Pirard, Catherine; De Pauw, Edwin ULg; Focant, Jean-François ULg

in Journal of Chromatography. A (2003), 998(1-2), 169-181

A strategy for determination of polybrominated diphenyl ethers, polychlorinated dibenzodioxins, polychlorinated dibenzofurans and polychlorinated biphenyls on fatty matrices has been established. After ... [more ▼]

A strategy for determination of polybrominated diphenyl ethers, polychlorinated dibenzodioxins, polychlorinated dibenzofurans and polychlorinated biphenyls on fatty matrices has been established. After extraction, the proposed method allows the purification and the fractionation of all target groups of compounds in a simple multi-step automated clean-up. Furthermore, their subsequent analysis is carried out using a single benchtop mass spectrometer, in four separate injections. Required sensitivity considering levels found in the environment is attained using electron impact ionisation followed by tandem in time mass spectrometry. The whole method has been evaluated on standard solution and quality control samples consisting of fortified beef fat. Sensitivity, selectivity, accuracy and repeatability were tested with satisfactory results. (C) 2003 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailNew Strategy for the Preparation of Clickable Peptides and Labeling with 1-(Azidomethyl)-4-[18F]-fluorobenzene for PET
Thonon, David ULg; Paris, Jérôme ULg; Kech, Cecile et al

in Bioconjugate Chemistry (2009), 20(4), 817-823

The alkyne-azide Cu(I)-catalyzed Huisgen cycloaddition, a click type reaction was used to label a peptide with fluorine-18. A novel solid phase synthesis approach for the preparation of clickable peptides ... [more ▼]

The alkyne-azide Cu(I)-catalyzed Huisgen cycloaddition, a click type reaction was used to label a peptide with fluorine-18. A novel solid phase synthesis approach for the preparation of clickable peptides has been developed and has also permitted the straightforward preparation of reference compounds. A complementary azide labeling agent (1-(azidomethyl)-4-[18F]-fluorobenzene) has been produced in a four step procedure in 75 min with a 34% radiochemical yield (decay corrected). Conjugation of [18F]fluoroazide with a model alkyne-neuropeptide produced the desired 18F-radiolabeled peptide in less than 15 min with a yield of 90% and excellent radiochemical purity [less ▲]

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See detailNew strategy for the validation of chromatographic bioanalytical methods
Chapuzet, E.; Mercier, N.; Bervoas-Martin, S. et al

in STP Pharma Pratiques (2000), 10(1), 21-38

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See detailA new strategy to improve the bovine resistance to respiratory disease or when respiratory physiology meets beef selection
Bureau, Fabrice ULg; Lekeux, Pierre ULg

in Wensing, Th (Ed.) Production Diseases in Farm Animals (1999)

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See detailNew strategy to in vitro evaluation of antimalarial drugs demonstre advantage of Artemisia annua crude extract on antimalarial effect by its tools to cross intestinal barrier
Melilo de Magalhaes, Pedro; Schneider, Y. J.; Dupont, Isabelle et al

Poster (2010, October 03)

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See detailNew strictosidine beta-glucosidase from Strychnos mellodora
Brandt, Viviane; Geerlings, Arjan; Tits, Monique ULg et al

in Plant Physiology & Biochemistry (2000), 38(3), 187-192

A stable strictosidine glucosidase was isolated from dried powdered material of Strychnos mellodora. The kinetic parameters Km and Vmax of the purified glucosidases from catharanthus roseus and S ... [more ▼]

A stable strictosidine glucosidase was isolated from dried powdered material of Strychnos mellodora. The kinetic parameters Km and Vmax of the purified glucosidases from catharanthus roseus and S. mellodora towards strictosidine, dolichantoside and palicoside were determined and compared. [less ▲]

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See detailNew Studies and Progress in Ne IV, V and VI Term Analysis
Bastin, Thierry ULg; Biémont, Emile ULg; Dumont, Paul-Dominique ULg et al

in Proceedings of the 5th International Colloquium on Atomic Spectra and Oscillator Strengths for Astrophysical and Laboratory Plasmas (1996)

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See detailA new subspace-based approach to identify nonlinear mechanical structures in the frequency domain
Noël, Jean-Philippe ULg; Kerschen, Gaëtan ULg

in Proceedings of the 16th IFAC Symposium on System Identification (2012, July)

This paper introduces a new frequency-domain subspace-based method for the identification of nonlinear mechanical systems. The technique exploits frequency data and interprets nonlinearities as feedback ... [more ▼]

This paper introduces a new frequency-domain subspace-based method for the identification of nonlinear mechanical systems. The technique exploits frequency data and interprets nonlinearities as feedback forces exciting the underlying linear system. It is demonstrated using two academic examples, a Duffing oscillator and a five degree-of-freedom system comprising two nonlinearities. [less ▲]

Detailed reference viewed: 36 (3 ULg)