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See detailLa NEPSY, outil d’évaluation neuropsychologique chez le jeune enfant. Approche critique.
Catale, Corinne ULg

Speech (2004)

L'objectif de cette conférence est de présenter la NEPSY, batterie neuropsychologique pour l'évaluation cognitive d'enfants âgés de 3 à 12 ans.

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See detailNeptune: l'apothéose de la mission Voyager
Manfroid, Jean ULg

Article for general public (1989)

Not Available

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See detailNeQuick: In-Depth Analysis and New Developments
Bidaine, Benoît ULg; Prieto-Cerdeira, Roberto; Orus, Raul

in 3rd ESA Workshop on Satellite Navigation User Equipment Technologies NAVITEC '2006 (2006, December)

An empirical model called NeQuick has been selected for the modelling and correction of the ionospheric delay contribution in GALILEO single frequency receivers. The current baseline version of NeQuick ... [more ▼]

An empirical model called NeQuick has been selected for the modelling and correction of the ionospheric delay contribution in GALILEO single frequency receivers. The current baseline version of NeQuick for GALILEO is the one available in the International Telecommunication Union – Radiocommunication Sector (ITU-R) since 2001. From that time, several improvements have been proposed leading to the need of a better understanding and comparison of these different versions and an analysis of the weaknesses. Better results have been obtained by means of simpler ionosonde and profile parameters calculations, different topside formulation and new data files. The interest of a newer version of NeQuick including the above-mentioned modifications is highlighted as its error behaviour towards latitude shows a better agreement with reality. Those modifications should be coupled to a less simplistic topside formulation involving several layers with appropriate transitions such as the proposal introduced in this paper. The need of a different treatment regarding the daily effective use of the model for GALILEO single frequency algorithm compared to a physical use (that uses monthly median underlying data) is addressed. For the analysis and comparison of the different variants of the model, a software tool with a Graphical User Interface was developed. Preliminary comparisons for the physical use between different versions and also between modelled and measured data are presented. Such comparisons should be extended in the future for the effective use of the model. Finally, the structure and analysis of the mentioned issues and the results of the different comparisons are shown. Also solutions or potential paths to investigate solutions are proposed. [less ▲]

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See detailNerf spinal accessoire
WANG, François-Charles ULg

in Lettre du Neurologue (La) : le Courrier du Spécialiste (2013), XVII(1), 16-20

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See detailNéron et la magie
Rochette, Bruno ULg

in Latomus : Revue d'Etudes Latines (2003), 62

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See detailNerve biopsy: indications and contribution to the diagnosis of peripheral neuropathy. The experience of the Born Bunge Foundation University of Antwerp and University of Liege between 1987 and 1997.
Deprez, Manuel ULg; Ceuterick-de Groote, C.; Schoenen, Jean ULg et al

in Acta Neurologica Belgica (2000), 100(3), 162-6

We reviewed 355 nerve biopsies analysed at the Laboratories of Neuropathology of the Born-Bunge Foundation/University of Antwerp (BBF/UIA) and University of Liege (ULg) between 1987 and 1997. We examined ... [more ▼]

We reviewed 355 nerve biopsies analysed at the Laboratories of Neuropathology of the Born-Bunge Foundation/University of Antwerp (BBF/UIA) and University of Liege (ULg) between 1987 and 1997. We examined the indications for nerve biopsy, the yield of the procedure, and the influence of clinical and neuropathological parameters. Contributory biopsies accounted for 35.5% and 47.3% respectively at ULg and BBF/UIA laboratories: of these, one third showed specific histological findings, the majority being informative only when combined with the relevant clinical data. The profile of indications for nerve biopsy was roughly comparable in both laboratories. The search for an inflammatory neuropathy prompted 35-40% of all biopsies with more than 50% of specimens being informative in this indication. The lowest yield (20%) was obtained among the nerve biopsies performed in the absence of any presumptive aetiology. These accounted for 22-33% of all cases. Inadequate surgical resection, delays in transport or processing errors precluded histological study of 4% (BBF/UIA) to 8% (ULg) of the specimens. We conclude that nerve biopsies should be performed by experienced surgeons and handled in specialised laboratories. Only a relatively small number of causes of neuropathy can be diagnosed on the basis of histology alone. More often, contributory biopsies will result from the combination of non-specific suggestive histological features with relevant clinical information. The diagnostic yield of nerve biopsy is function of careful patient selection and close collaboration between the clinician and the neuropathologist. [less ▲]

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See detailNervensystem und Wärmeproduction
Fredericq, Léon ULg

in Pflügers Archiv : European Journal of Physiology (1886), XXXVIII

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See detailNerves’ impact on voice of 26 students in a music exam situation.
Morsomme, Dominique ULg; Ficarrotta, Eva

Conference (2010, July 17)

The manifestations of the nerves are physical, cognitive and behavioural. They vary according to the genre, the task and the public. According to the literature, many vocal parameters are influenced by ... [more ▼]

The manifestations of the nerves are physical, cognitive and behavioural. They vary according to the genre, the task and the public. According to the literature, many vocal parameters are influenced by the exam nerves. Our goal is to study the manifestations of the nerves in 26 students (10 men and 16 women, mean age: 33.3 y) during their musical examination. They sang a score “a cappella”. We recorded the musical performance 4 months before examination (T1), the day before (T2) and the examination's day (T3). Each student evaluated his global degree of nervousness, filled in the Cungi’s scales (stress scale) and explained his strategy of coping. 2 expert judges noted the students at the T3. A speech therapist also evaluated them on the basis of 4 objective criteria. Moreover, we measured the frequency parameters, jitter, intensity, duration and HNR with Praat. The comparison of the results at each time shows that the men and the women obtain results significantly higher at T3 for their degrees of nervousness and their level of intensity. In the same way, the note evaluated by the judges for the whole of the subjects is correlated with that of the speech therapist (rho: 0.71; 0.79). For the women at T3, we observe five positive correlations and one negative. The more the women evaluate their degree of stress strongly, the more judge n°2 evaluates it strongly (rho: 0.84). The more the scores on the scales of Cungi are high, the higher are the degrees of perfectionism (rho: 0.87; 0.81; 0.57). Both judges evaluated the exam nerves in the same way (rho: 0.59). The longer the execution time of the musical score, the more the evaluations by the speech therapist and both judges are weak (rho: -0.69). For the men at T3, we observe six positive correlations and two negative. The more the men have a high degree of nervousness, the higher the judges evaluated exam nerves, the higher level of Cungi scores the more the degree of perfectionism is high (rho: 0.69; 0.65; 0.72; 0.68). The more the jitter increases, the more the perception of the exam nerves by judge n°2 is high (rho: 0.68). The more the HNR increased, the more the degree of exam nerves evaluated by the judges is important (rho: 0.71) and the more the note of the speech pathologist is weak (rho: -0.71). The higher the jitter is, the weaker are the notes of the judges and of the speech pathologist (rho: -0.78; -0.79). 17 students, including only one man, employed strategies of coping to decrease their nerves: 73% a coping cognitive behavioural and 16% a medical strategy. In our study, the nerves affect the men and the women differently. The management of the nerves is an interesting topic to study in order to contribute to the development of coping strategies. [less ▲]

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See detailNervous system injury: focus on the inflammatory cytokine 'granulocyte-macrophage colony stimulating factor'
Franzen, Rachelle ULg; Bouhy, D.; Schoenen, Jean ULg

in Neuroscience Letters (2004), 361(1-3), 76-78

Any lesion in the nervous system, be it infectious, immunopathological, ischemic or traumatic, is followed by an inflammatory process that induces rapid activation of glial cells and additional ... [more ▼]

Any lesion in the nervous system, be it infectious, immunopathological, ischemic or traumatic, is followed by an inflammatory process that induces rapid activation of glial cells and additional recruitment of granulocytes, T-cells and monocytes/macrophages from the blood stream. Neuroinflammation is a double-sided sword. It can cause neuronal damage and participate in neuropathic pain, but it also has neuroprotective and neurotrophic effects at some stages. Cytokines are the main molecular actors of this 'network of inflammation'. Among them, granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pro-inflammatory hematopoietic cytokine widely used in haematological disorders to stimulate proliferation and differentiation of neutrophilic, eosinophilic and monocytic lineages. GM-CSF and its receptor are expressed in the brain and the cytokine can cross the blood-brain barrier. It is thus likely to affect various nervous system functions. This review will focus on the role of GM-CSF in nervous system disorders and their experimental models with particular emphasis on its possible beneficial effect on axonal regeneration after PNS and CNS injury. (C) 2004 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailNESCAV - Premiers résultats
Streel, Sylvie ULg; Donneau, Anne-Françoise ULg; Hoge, Axelle ULg et al

Conference (2011, December 02)

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See detailNescio als 'Animal Metaphysicum'
Yans, Baudoin ULg

in Spiegel der Letteren (1994), (1), 45-62

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See detailNest grouping patterns of bonobos (Pan paniscus) in relation to fruit availability in a forest-savannah mosaic
Serckx, Adeline ULg; Huynen, Marie-Claude ULg; Bastin, Jean-François ULg et al

in PLoS ONE (2014)

A topic of major interest in socio-ecology is the comparison of chimpanzees and bonobos’ grouping patterns. Numerous studies have highlighted the impact of social and environmental factors on the ... [more ▼]

A topic of major interest in socio-ecology is the comparison of chimpanzees and bonobos’ grouping patterns. Numerous studies have highlighted the impact of social and environmental factors on the different evolution in group cohesion seen in these sister species. We are still lacking, however, key information about bonobo social traits across their habitat range, in order to make accurate inter-species comparisons. In this study we investigated bonobo social cohesiveness at nesting sites depending on fruit availability in the forest-savannah mosaic of western Democratic Republic of Congo (DRC), a bonobo habitat which has received little attention from researchers and is characterized by high food resource variation within years. We collected data on two bonobo communities. Nest counts at nesting sites were used as a proxy for night grouping patterns and were analysed with regard to fruit availability. We also modelled bonobo population density at the site in order to investigate yearly variation. We found that one community density varied across the three years of surveys, suggesting that this bonobo community has significant variability in use of its home range. This finding highlights the importance of forest connectivity, a likely prerequisite for the ability of bonobos to adapt their ranging patterns to fruit availability changes. We found no influence of overall fruit availability on bonobo cohesiveness. Only fruit availability at the nesting sites showed a positive influence, indicating that bonobos favour food ‘hot spots’ as sleeping sites. Our findings have confirmed the results obtained from previous studies carried out in the dense tropical forests of DRC. Nevertheless, in order to clarify the impact of environmental variability on bonobo social cohesiveness, we will need to make direct observations of the apes in the forest-savannah mosaic as well as make comparisons across the entirety of the bonobos’ range using systematic methodology. [less ▲]

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See detailA nested model of the Cariaco Basin (Venezuela): description of the basin’s interior hydrography and interactions with the open ocean
Alvera Azcarate, Aïda ULg; Barth, Alexander ULg; Weisberg, Robert H.

in Ocean Dynamics (2009), 59(1), 97-120

A high-resolution (1/60°), three-dimensional numerical circulation model of the Cariaco Basin (Venezuela) is constructed by nesting the Regional Ocean Modeling System (ROMS) in the 1/12° global Hybrid ... [more ▼]

A high-resolution (1/60°), three-dimensional numerical circulation model of the Cariaco Basin (Venezuela) is constructed by nesting the Regional Ocean Modeling System (ROMS) in the 1/12° global Hybrid Coordinate Ocean Model (HYCOM). A new bathymetry, computed by merging DBDB2 data and in situ depth measurements using optimal interpolation, is described. This new bathymetry corrects the depth of the channels that connect the Cariaco Basin with the open ocean and which play a very important role in the basin circulation. Results from a 2004 ROMS hindcast are presented. Observations (temperature, salinity, and currents) are used to validate the model results before using the model to describe the annual cycle of the Cariaco Basin and the interactions between the basin and the open ocean. Two modes of interaction are described, the first being the meanders and eddies that travel westward with the Caribbean Current, and the second being a subsurface eastward current that flows along the north coast of South America. The circulation path within the basin is directly related to the intensity of this current. Both mechanisms described play a role in the ventilation of the basin. The present study is also an example of the feasibility of one of the objectives of GODAE (Global Ocean Data Assimilation Experiment): downscaling from a large-scale model to a regional model. In particular, the nesting ratio of 5 used in this work demonstrates that a high-resolution model can be successfully nested in HYCOM. [less ▲]

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See detailA Nested Model of the Cariaco Basin: Study of the Hydrography and Interactions with the Open Ocean
Alvera Azcarate, Aïda ULg; Barth, Alexander ULg; Virmani, J. I. et al

Conference (2007)

The circulation of the Cariaco Basin (Venezuela) is modeled using the Regional Ocean Model System (ROMS) nested in the global 1/12 degree Hybrid Coordinate Ocean Model (HYCOM). The objective of this work ... [more ▼]

The circulation of the Cariaco Basin (Venezuela) is modeled using the Regional Ocean Model System (ROMS) nested in the global 1/12 degree Hybrid Coordinate Ocean Model (HYCOM). The objective of this work is to obtain a better understanding of the Cariaco Basin circulation by studying the processes that link the basin with the Caribbean Sea. To our knowledge, this is the first attempt to model the circulation in the Cariaco Basin with a nested high resolution hydrodynamical model. In particular, we examined the interaction of the Cariaco Basin with the large-scale, open-ocean processes, as the westward Caribbean Current and the eastward subsurface counter-current flowing along the South America Caribbean coast. These two current systems connect the Cariaco Basin with the Caribbean Sea waters, and therefore are directly related to the ventilation of the basin. By studying the kinematics and dynamics of the Cariaco Basin we anticipate gaining a better understanding on how the past conditions affected the basin characteristics and hence the geological records obtained from the basin sediments. We will report on several years of observations from the continuous monitoring of currents within the basin, plus analyses of year-long model runs that provide a basin-wide, three-dimensional context for the circulation. [less ▲]

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See detailA Nested Model of the West Florida Shelf: Assimilation of High-Frequency Radar Currents and study of Loop Current generated flow
Barth, Alexander ULg; Alvera Azcarate, Aïda ULg; Zheng, L. et al

Conference (2008)

High-Frequency Radar Currents are assimilated in a West Florida Shelf (WFS) model based on the Regional Ocean Model System (ROMS) which is nested in the Atlantic Hybrid Coordinate Ocean Model (HYCOM) to ... [more ▼]

High-Frequency Radar Currents are assimilated in a West Florida Shelf (WFS) model based on the Regional Ocean Model System (ROMS) which is nested in the Atlantic Hybrid Coordinate Ocean Model (HYCOM) to include both local and deep-ocean forcing, particularly the Gulf of Mexico Loop Current (LC). An ensemble simulation of the WFS ROMS model is carried out under different wind forcings in order to estimate the error covariance of the model state vector and the covariance between ocean currents and winds. Radial currents measured by HF-Radar antennas near St. Petersburg and Venice, FL, are assimilated using this ensemble-based error covariance. Different assimilation techniques using a time-average ensemble, a filter to reduce surface-gravity waves and an extended state vector including wind stress were tested. Results of WFS ROMS model assimilating surface currents show an improvement of the model currents not only at the surface but also at depth. The LC is a highly unstable current which generates large anticyclones traveling to the West but also a series of smaller anticyclones and filaments moving to the East and affecting the West Florida shelf. An additional tracer is included in the model simulation to track the presence of LC water. With this tracer, the total amount of LC water reaching the shelf and its mechanism is studied. [less ▲]

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See detailA nested model study of the Loop Current generated variability and its impact on the West Florida Shelf
Barth, Alexander ULg; Alvera Azcarate, Aïda ULg; Weisberg, R. H.

in Journal of Geophysical Research. Oceans (2008), 113(C5),

A West Florida Shelf model based on the Regional Ocean Modeling System (ROMS) is nested in the North Atlantic Hybrid Coordinate Ocean Model (NAT HYCOM). The focus of this work is the study of the impact ... [more ▼]

A West Florida Shelf model based on the Regional Ocean Modeling System (ROMS) is nested in the North Atlantic Hybrid Coordinate Ocean Model (NAT HYCOM). The focus of this work is the study of the impact of the Loop Current on the West Florida Shelf. In order to assess the model's accuracy, it is compared quantitatively to in situ temperature and velocity measurements on the shelf. A series of sensitivity experiments are conducted to determine the appropriate wind forcing, sea surface temperature relaxation, and mixing scheme. By the inclusion of the Loop Current, we are able to study the propagation of an anticyclonic vortex detaching from the Loop Current. We found that the ambient gradient of potential vorticity is able to explain the vortex path and speed. The statistics of such Loop Current generated flow features were examined by including a tracer marking Loop Current water. This allows to track the Loop Current water on the West Florida Shelf and to quantify the amount of Loop Current water reaching the shelf. [less ▲]

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See detailA nested-grid model with data assimilation in the Gulf of Lions
Vandenbulcke, Luc ULg; Barth, Alexander ULg; Alvera Azcarate, Aïda ULg et al

Conference (2004, April)

When a model combines the use of nested grids and data assimilation, a preliminary, simple, 1D test case showed the interest of combining the different state vectors coming from the different grids, into ... [more ▼]

When a model combines the use of nested grids and data assimilation, a preliminary, simple, 1D test case showed the interest of combining the different state vectors coming from the different grids, into one single vector, and using global error matrices covering all the grids at once. In this case, the assimilation procedure provides errorspace feedback from the fine grid to the coarser grid, which proves to be even more important than the statevector feedback. For data located in the fine grid, assimilation of the same data in the coarse grids is not necessary anymore, as both model and errorspace feedback is performed during assimilation. Large data transfers from local to basin-scale models can be avoided. The GHER hydrodynamic model (for a full description, see e.g. [1]) is applied to a three times nested model covering (a) the Mediterrannean Sea at 1/4 degree, (b) the Liguro-Provencal Bassin at 1/20 degree, and (c) the Gulf of Lions at 1/100 degree. The simulation starts on Januari 1st, 1998, using ECMWF atmospheric forcings and MODB4/MEDAR climatic data. As the model allows mode splitting, the simulation uses 2D timesteps of 3 seconds, and 3D timesteps of 3 minutes, on each grid. A twin experiment is performed. The perturbed initial condition is a delayed model state of the reference run. An initial reduced-rank model errorspace is constructed from 20 EOFs, themselves built from the reference run, over all three grids at the same time. Surface temperature and salinity from the reference run are assimilated in the model every 24 hours, using reduced-rank optimal interpolation (see [2]). Different simulations are implemented, using different ways to combine grid nesting and data assimilation: with or without state vector feedback, with data assimilation only in the local grid, or in the coarser grids, or both, and with or without errorspace feedback (i.e. with 3 separated statevectors or with one global statevector). The comparison of those experiments comfirms that using one global statevector reduces the error in the coarser grids much faster. The effect of data assimilation, and the performances of the different methods, can be examined by calculating RMS errors between the perturbed runs and the reference run. They can also be observed by following the model state trajectory in the EOFspace (for example, using the first three EOFs). In the context of the twin experiment described above, the first assimilation cycle clearly brings the model back in time. This is consistent with the choice of the perturbed initial conditions, being a delayed state of the reference run. The following assimilation cycles have little effect, as the trajectory is already almost brought back on the reference trajectory. If other parameters are modified too (e.g. the atmospheric fluxes), each assimilation cycle has an important effect on the modelstate trajectory. A new experiment performs assimilation in the Gulf of Lions in the spring of 1998 using real observations. Different variables can be assimilated, using data collected during the FETCH campaign: NOAA/AVHRR SST, temperature and salinity from Atalante CTDs, or altimetric data from the ERS2 or TOPEX satellites. [less ▲]

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See detailNestin expression in cultivated mesenchymal stem cells: Regulation and potential role in their neural differentiation
Wislet-Gendebien, Sabine ULg; Leprince, Pierre ULg; Moonen, Gustave ULg et al

in Glia (2002, May), (Suppl. 1), 87

Bone marrow stromal cells can differentiate into many types of mesenchymal cells, i.e. osteocyte, chondrocyte, fibroblast and adipocyte, but can also differentiate into non-mesenchymal cell, i.e. neural ... [more ▼]

Bone marrow stromal cells can differentiate into many types of mesenchymal cells, i.e. osteocyte, chondrocyte, fibroblast and adipocyte, but can also differentiate into non-mesenchymal cell, i.e. neural cells in appropriate in vivo experimental conditions (Kopen and al.,PNAS,96, 10711,1999, Brazelton and al, Science, 290,1175, 2000, Mezey and al, Science, 290,1179, 2000). In neurological disorders, such as Alzheimer's and Parkinson's diseases, auto-transplantation of neural cell types derived from mesenchymal stem cells offers the potential of replacing lost cells and recovering lost functions. Nestin is an intermediate filament protein predominantly expressed by neural stem cells and is used to identify neural progenitor. In this study, we demonstrate that cultured rat mesenchymal stem cells (rMSC) can express nestin in appropriate conditions. Two factors contribute to the regulation of nestin expression by rMSC : 1) the presence of serum-derived components in the culture medium which repress nestin expression and 2) the cell’s number of passages. LPA and thrombin mimic this serum effect. Furthermore, when nestin- positive cells are trypsinized and resuspended into culture conditions used for neural stem cells (NSC), sphere formation is observed. Likewise, by co-cultivating nestin-positive rMSC with NSC derived from green mouse, heterogenous spheres were obtained. When those heterogenous spheres are placed on polyornithine-coated surfaces, a differentiation of some rMSC into GFAP-positive cells occurs. These results indicate that nestin expression might be a pre-requisite for the acquisition by rMSC of the capacity to differentiate into some neural cell types. [less ▲]

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