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Peer Reviewed
See detailNew relative K+-sparing high ceiling diuretics related to torasemide
Masereel, B.; Schynts, M.; Lohrmann, E. et al

Conference (1992)

Detailed reference viewed: 1 (0 ULg)
Peer Reviewed
See detailNew relative K+-sparing high ceiling diuretics related to torasemide
Masereel, B.; Schynts, M.; Lohrmann, E. et al

in Journal de Pharmacie de Belgique (1992), 47

Detailed reference viewed: 2 (0 ULg)
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Peer Reviewed
See detailA new representative of the lichid genus Ohleum (Trilobita) from the Eifelian (Middle Devonian) of southern Belgium
Taghon, Peter; Bonino, Enrico; Mottequin, Bernard ULg

in Geologica Belgica (2012), 15(3), 120-125

Trilobites of the family Lichidae are relatively poorly diversified within the Eifelian mixed siliciclastic-carbonate succession of the southern margin of the Dinant Synclinorium (Belgium). Until now ... [more ▼]

Trilobites of the family Lichidae are relatively poorly diversified within the Eifelian mixed siliciclastic-carbonate succession of the southern margin of the Dinant Synclinorium (Belgium). Until now, they were only represented by species belonging to the genera Ceratarges and Eifliarges. The recent discovery of a well-preserved specimen within the Eifelian-aged Jemelle Formation in the Couvin area led us to propose the first detailed description of a representative of the genus Ohleum (Ohleum magreani sp. nov.) in the Ardennes. [less ▲]

Detailed reference viewed: 217 (12 ULg)
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See detailNew Research for Periods of Ap Stars Observed at the ESO - III
Renson, Pierre ULg; Manfroid, Jean ULg

in Information Bulletin on Variable Stars (1979), 1658

Not Available

Detailed reference viewed: 5 (2 ULg)
See detailNew Results from the Excavations in the Northern Domestic Quarter (Field B)
Van der Stede, Véronique ULg

Scientific conference (2007, October 11)

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Peer Reviewed
See detailNew Results in Exclusive Hard Reactions
Pire, Bernard; Semenov-Tyan-Shanskiy, Kirill ULg; Szymanowski, Lech et al

in PoS - Proceedings of Science (2011), EPS-HEP2011

Detailed reference viewed: 8 (0 ULg)
See detailNew results in the defensive chemistry of Crematogaster ants
Laurent, Pascal ULg; Hamdani, Anissa; Braekman, Jean-Claude et al

Poster (2002)

Ants of the genus Crematogaster are able to raise their abdomen forwards and over the thorax and head. In many Crematogaster species, the venom is emitted as a froth that accumulates on the spatulate ... [more ▼]

Ants of the genus Crematogaster are able to raise their abdomen forwards and over the thorax and head. In many Crematogaster species, the venom is emitted as a froth that accumulates on the spatulate portion and at the basis of the sting, and thus can be easily applied to the integument of enemies. In the three European species of Crematogaster ants, the Dufour gland contains complex mixtures of long chain derivatives bearing a (E,E)-cross-conjugated dienone linked to a primary acetate function. When the venom is emitted, these compounds are transformed into highly electrophilic and toxic 4-oxo-2,5-dienals by an esterase and an oxidase stored in the poison gland. On the other hand, the Dufour gland of one Crematogaster species from Papua-New Guinea produces long chain furan derivatives, whereas two Brazilian species produce furanocembrene diterpenes. To further investigate the defensive mechanisms in this genus and to assess whether the composition of the Dufour gland secretion could be used for taxonomic purposes, we have now studied two other Crematogaster species. The Dufour gland of C. nigriceps from Africa contains a mixture of l-alkyl-l,3,5-cyclohexanetriols. In C. montezumia, collected in Argentina, the defensive mechanism is based on the production of triacylglycerols bearing polyunsaturated fatty acids containing (Z,Z,Z)-conjugated trienes or (5E,8Z,10Z,12Z)-tetraenes, which are responsible for the strong sticking properties of the secretion. [less ▲]

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See detailNew results in the defensive chemistry of Crematogaster ants
Laurent, Pascal ULg; Hamdani, Anissa; Braekman, Jean-Claude et al

Poster (2002)

Ants of the genus Crematogaster are able to raise their abdomen forwards and over the thorax and head. In many Crematogaster species, the venom is emitted as a froth that accumulates on the spatulate ... [more ▼]

Ants of the genus Crematogaster are able to raise their abdomen forwards and over the thorax and head. In many Crematogaster species, the venom is emitted as a froth that accumulates on the spatulate portion and at the basis of the sting, and thus can be easily applied to the integument of enemies. In the three European species of Crematogaster ants, the Dufour gland contains complex mixtures of long chain derivatives bearing a (E,E)-cross-conjugated dienone linked to a primary acetate function. When the venom is emitted, these compounds are transformed into highly electrophilic and toxic 4-oxo-2,5-dienals by an esterase and an oxidase stored in the poison gland. On the other hand, the Dufour gland of one Crematogaster species from Papua-New Guinea produces long chain furan derivatives, whereas two Brazilian species produce furanocembrene diterpenes. To further investigate the defensive mechanisms in this genus and to assess whether the composition of the Dufour gland secretion could be used for taxonomic purposes, we have now studied two other Crematogaster species. The Dufour gland of C. nigriceps from Africa contains a mixture of l-alkyl-l,3,5-cyclohexanetriols. In C. montezumia, collected in Argentina, the defensive mechanism is based on the production of triacylglycerols bearing polyunsaturated fatty acids containing (Z,Z,Z)-conjugated trienes or (5E,8Z,10Z,12Z)-tetraenes, which are responsible for the strong sticking properties of the secretion. [less ▲]

Detailed reference viewed: 16 (1 ULg)
See detailNew results in the defensive chemistry of Crematogaster ants
Laurent, Pascal ULg; Hamdani, Anissa; Braekman, Jean-Claude et al

Poster (2002)

Ants of the genus Crematogaster are able to raise their abdomen forwards and over the thorax and head. In many Crematogaster species, the venom is emitted as a froth that accumulates on the spatulate ... [more ▼]

Ants of the genus Crematogaster are able to raise their abdomen forwards and over the thorax and head. In many Crematogaster species, the venom is emitted as a froth that accumulates on the spatulate portion and at the basis of the sting, and thus can be easily applied to the integument of enemies. In the three European species of Crematogaster ants, the Dufour gland contains complex mixtures of long chain derivatives bearing a (E,E)-cross-conjugated dienone linked to a primary acetate function. When the venom is emitted, these compounds are transformed into highly electrophilic and toxic 4-oxo-2,5-dienals by an esterase and an oxidase stored in the poison gland. On the other hand, the Dufour gland of one Crematogaster species from Papua-New Guinea produces long chain furan derivatives, whereas two Brazilian species produce furanocembrene diterpenes. To further investigate the defensive mechanisms in this genus and to assess whether the composition of the Dufour gland secretion could be used for taxonomic purposes, we have now studied two other Crematogaster species. The Dufour gland of C. nigriceps from Africa contains a mixture of l-alkyl-l,3,5-cyclohexanetriols. In C. montezumia, collected in Argentina, the defensive mechanism is based on the production of triacylglycerols bearing polyunsaturated fatty acids containing (Z,Z,Z)-conjugated trienes or (5E,8Z,10Z,12Z)-tetraenes, which are responsible for the strong sticking properties of the secretion. [less ▲]

Detailed reference viewed: 19 (1 ULg)
See detailNew results on forbidden transitions of [FE II], [FE III], [FE V], [FE VII], and [FE X] in stellar spectra
Swings, Polydore ULg; Struve, O.

in Publications of the American Astronomical Society (1946)

Detailed reference viewed: 5 (0 ULg)
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See detailNew results on the UV Io footprint morphology and brightness
Bonfond, Bertrand ULg; Grodent, Denis ULg; Gérard, Jean-Claude ULg et al

Poster (2008, April 18)

The Io UV footprint is an auroral feature on Jupiter caused by the electromagnetic interaction between the satellite Io and the Jovian magnetosphere. The footprint morphology and the spots multiplicity ... [more ▼]

The Io UV footprint is an auroral feature on Jupiter caused by the electromagnetic interaction between the satellite Io and the Jovian magnetosphere. The footprint morphology and the spots multiplicity have been found to vary with the location of Io in the plasma torus. We show recent Hubble Space Telescope (HST) images that reveal a new feature in the footprint: a faint leading spot that appears upstream of the main spot in one hemisphere when Io is close to the opposite border of the torus. A possible interpretation relates the leading spots and one downward secondary spot to electron beams generated by downstream currents in the opposite hemisphere. We also present a 3D model of the Io footprint emissions in the 100 to 170 nm wavelength range. Comparisons between this model and the HST images enable us to study the actual size and shape of the different Io footprint features. It also allows to measure the footprint brightness on the new images with a better estimation of the geometric effects (e.g. limb brightening). The observations presented here provide critical constraints to the Io-plasma torus interaction modeling. [less ▲]

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See detailNew results on the variability of some WN stars
Gosset, Eric ULg; Vreux, Jean-Marie ULg; Manfroid, Jean ULg et al

in Davidson, K.; Moffat, A. F. J.; Lamers, H.J.G.L.M. (Eds.) Physics of Luminous Blue Variables (1989)

Not Available

Detailed reference viewed: 9 (1 ULg)
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Peer Reviewed
See detailNew ribonucleotide reductase inhibitor, (E)-2′-deoxy-(fluromethylene) cytidine, acts as a radiosensitizer on human colon and cervix cancer cell lines
Coucke, Philippe ULg; LI, XY; Cottin, E et al

in Radiotherapy & Oncology (1996), 40(Supplément 1), 135

Detailed reference viewed: 9 (4 ULg)
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Peer Reviewed
See detailNew role for Emerin, a key inner nuclear membrane protein, as an enhancer of the autophagosome formation in the C16-ceramide autophagy pathway.
Deroyer, Céline ULg; Renert, Anne-Françoise; Merville, Marie-Paule ULg et al

in Autophagy (2014)

To date, precise roles of EMD remain poorly described. In this paper, we investigate the role of EMD in the C16-ceramide autophagy pathway. Ceramides are bioactive signalling molecules acting notably in ... [more ▼]

To date, precise roles of EMD remain poorly described. In this paper, we investigate the role of EMD in the C16-ceramide autophagy pathway. Ceramides are bioactive signalling molecules acting notably in the regulation of cell growth, differentiation or cell death. However, the mechanisms by which they mediate these pathways are not fully understood. We found that C16-ceramide induces EMD phosphorylation on its LEM domain through PRKACA. Upon ceramide treatment, phosphorylated EMD binds LC3 leading to an increase of the autophagosomes formation. These data suggest a new role of EMD as an enhancer of autophagosomes formation in the C16-ceramide autophagy pathway in colon cancer cells. [less ▲]

Detailed reference viewed: 95 (18 ULg)
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See detailA new role for histone deacetylase 5 in the maintenance of long telomeres.
Novo, Clara Lopes; Polese, Catherine ULg; Matheus, Nicolas ULg et al

in FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2013), 27

Telomeres are major regulators of genome stability and cell proliferation. A detailed understanding of the mechanisms involved in their maintenance is of foremost importance. Of those, telomere chromatin ... [more ▼]

Telomeres are major regulators of genome stability and cell proliferation. A detailed understanding of the mechanisms involved in their maintenance is of foremost importance. Of those, telomere chromatin remodeling is probably the least studied; thus, we intended to explore the role of a specific histone deacetylase on telomere maintenance. We uncovered a new role for histone deacetylase 5 (HDAC5) in telomere biology. We report that HDAC5 is recruited to the long telomeres of osteosarcoma- and fibrosarcoma-derived cell lines, where it ensures proper maintenance of these repetitive regions. Indeed, depletion of HDAC5 by RNAi resulted in the shortening of longer telomeres and homogenization of telomere length in cells that use either telomerase or an alternative mechanism of telomere maintenance. Furthermore, we present evidence for the activation of telomere recombination on depletion of HDAC5 in fibrosarcoma telomerase-positive cancer cells. Of potential importance, we also found that depletion of HDAC5 sensitizes cancer cells with long telomeres to chemotherapeutic drugs. Cells with shorter telomeres were used to control the specificity of HDAC5 role in the maintenance of long telomeres. HDAC5 is essential for the length maintenance of long telomeres and its depletion is required for sensitization of cancer cells with long telomeres to chemotherapy. -Novo, C. L., Polese, C., Matheus, N., Decottignies, A., Londono-Vallejo, A., Castronovo, V., Mottet, D. A new role for histone deacetylase 5 in the maintenance of long telomeres. [less ▲]

Detailed reference viewed: 96 (24 ULg)
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See detailNew Role For Hpar-1 Kinases Emk And C-Tak1 In Regulating Localization And Activity Of Class Iia Histone Deacetylases
Dequiedt, Franck ULg; Martin, Maud ULg; Von Blume, Julia et al

in Molecular and Cellular Biology (2006), 26(19), 7086-102

Class IIa histone deacetylases (HDACs) are found both in the cytoplasm and in the nucleus where they repress genes involved in several major developmental programs. In response to specific signals, the ... [more ▼]

Class IIa histone deacetylases (HDACs) are found both in the cytoplasm and in the nucleus where they repress genes involved in several major developmental programs. In response to specific signals, the repressive activity of class IIa HDACs is neutralized through their phosphorylation on multiple N-terminal serine residues and 14-3-3-mediated nuclear exclusion. Here, we demonstrate that class IIa HDACs are subjected to signal-independent nuclear export that relies on their constitutive phosphorylation. We identify EMK and C-TAK1, two members of the microtubule affinity-regulating kinase (MARK)/Par-1 family, as regulators of this process. We further show that EMK and C-TAK1 phosphorylate class IIa HDACs on one of their multiple 14-3-3 binding sites and alter their subcellular localization and repressive function. Using HDAC7 as a paradigm, we extend these findings by demonstrating that signal-independent phosphorylation of the most N-terminal serine residue by the MARK/Par-1 kinases, i.e., Ser155, is a prerequisite for the phosphorylation of the nearby 14-3-3 site, Ser181. We propose that this multisite hierarchical phosphorylation by a variety of kinases allows for sophisticated regulation of class IIa HDACs function. [less ▲]

Detailed reference viewed: 46 (10 ULg)
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See detailA new role for NF-kappaB in angiogenesis inhibition.
Tabruyn, Sébastien ULg; Griffioen, A. W.

in Cell Death & Differentiation (2007), 14(8), 1393-7

Detailed reference viewed: 9 (2 ULg)
See detailA new role for the PP2A regulatory subunit Balpha in angiogenesis
Martin, Maud ULg

Conference (2010)

Detailed reference viewed: 8 (0 ULg)
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Peer Reviewed
See detailNEW ROTATIONAL ANALYSIS OF THE ALPHA-1-PI-CHI-1-SIGMA+ TRANSITION OF ALBR
BREDOHL, Harald; DUBOIS, Iwan; Mahieu, Emmanuel ULg et al

in Journal of Molecular Spectroscopy (1991), 145(1), 12-17

Twenty-eight bands of the A1Π-X1Σ+ transition have been fully analyzed. The vibrational constants obtained for the A1Π state do not agree with earlier data. On the other hand the observations suggest that ... [more ▼]

Twenty-eight bands of the A1Π-X1Σ+ transition have been fully analyzed. The vibrational constants obtained for the A1Π state do not agree with earlier data. On the other hand the observations suggest that the conclusion about the predissociation ought to be revised. [less ▲]

Detailed reference viewed: 26 (3 ULg)