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See detailInvestigation on the equivalent viscous damping in direct displacement-based design
Degée, Hervé ULg; Bento, R.; Massena, B.

Report (2007)

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See detailInvestigation on the High Efficiency Volume Bragg gratings performances for spectrometry in space environment: Preliminary results
Loicq, Jerôme ULg; Georges, Marc ULg; Gaspar Venancio, Luis Miguel

in Telescope and systems (2012, July)

The special properties of Volume Bragg Gratings (VBGs) make them good candidates for spectrometry applications where high spectral resolution, low level of straylight and low polarisation sensitivity are ... [more ▼]

The special properties of Volume Bragg Gratings (VBGs) make them good candidates for spectrometry applications where high spectral resolution, low level of straylight and low polarisation sensitivity are required. Therefore it is of interest to assess the maturity and suitability of VBGs as enabling technology for future ESA missions with demanding requirements for spectrometry. The VBGs suitability for space application is being investigated in the frame of a project led by CSL and funded by the European Space Agency. The goal of this work is twofold: first the theoretical advantages and drawbacks of VBGs with respect to other technologies with identical functionalities are assessed, and second the performances of VBG samples in a representative space environment are experimentally evaluated. The performances of samples of two VBGs technologies, the Photo-Thermo-Refractive (PTR) glass and the DiChromated Gelatine (DCG), are assessed and compared in the H, O2-B and NIR bands. The tests are performed under vacuum condition combined with temperature cycling in the range of 200 K to 300K. A dedicated test bench experiment is designed to evaluate the impact of temperature on the spectral efficiency and to determine the optical wavefront error of the diffracted beam. Furthermore the diffraction efficiency degradation under gamma irradiation is assessed. Finally the straylight, the diffraction efficiency under conical incidence and the polarisation sensitivity is evaluated. [less ▲]

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See detailInvestigation on the Role of the Viral Semaphorin encoded by the A3 Gene of Alcelaphine Herpesvirus 1 in the Induction of Malignant Catarrhal Fever
Myster, Françoise ULg; Palmeira, Leonor ULg; Vanderplasschen, Alain ULg et al

Poster (2011, July)

Alcelaphine herpesvirus 1 (AlHV-1) is a gammaherpesvirus carried by wildebeest asymptomatically. AlHV-1 is however responsible for the development of malignant catarrhal fever (MCF) when cross-species ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV-1) is a gammaherpesvirus carried by wildebeest asymptomatically. AlHV-1 is however responsible for the development of malignant catarrhal fever (MCF) when cross-species transmitted to a variety of ruminant susceptible species. Wildebeest-derived (WD)-MCF is a fatal lymphoproliferative and degenerative disease of ruminants. Experimentally, WD-MCF can be reproduced in rabbits. A3 ORF encodes a putative semaphorin homolog protein, named AlHV-sema. Semaphorins are secreted and membrane-associated proteins characterized by a conserved ‘Sema’ domain. Initially identified as guidance factors assisting axons pathfinding during neural development, semaphorins have been shown over the last decade to have significant functions in various processes of immunoregulation. Phylogenetic analyses revealed that AlHV-sema and mammals Sema7A have a common ancestor and that AlHV-Sema has evolved independently of other viral semaphorins. Further bioinformatics analyses demonstrated that AlHV-Sema and cellular Sema7A share a highly similar tridimensional structure. In order to investigate the role of AlHV-Sema in WD-MCF induction, we used the AlHV-1 BAC clone and produced a strain deleted for A3 and a revertant strain. The strain deleted for A3 replicated comparably to the wild-type parental strain in vitro. In vivo, rabbits infected with the strain deleted for A3 developed WD-MCF with a small but significant delay compared to those infected with the parental and revertant strains. Deletion of A3 did not affect the increase of viral genomic charge over time in peripheral blood and in lymph nodes at time of death and the major histopathological lesions were present in all groups. Though infection with wild-type and revertant strains resulted in the inversion of CD8 over CD4 ratio and increased IFN- production in lymphoid tissues at time of death, both parameters were significantly reduced after infection with the A3 deleted strain. Together, these results suggest that AlHV-Sema play a role in the host response to AlHV-1 infection. [less ▲]

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See detailAn investigation on the sliding of pallets on storage racks subjected to earthquake
Degée, Hervé ULg; Denoël, Vincent ULg

in Proceedings of the 7th National Congres on Theoretical and Applied Mechanics (2006)

This article presents some basic aspects of a research about the evaluation of the effect of earthquakes on storage racking systems. In particular, it focuses on the possible sliding and friction of the ... [more ▼]

This article presents some basic aspects of a research about the evaluation of the effect of earthquakes on storage racking systems. In particular, it focuses on the possible sliding and friction of the stored good subjected to a horizontal inertial force. In the first part, a theoretical SDOF system is studied to derive general indications on the sliding behavior and to serve as a reference for the validation of a more advanced numerical model. The second part presents then an application of the numerical model to simple rack structures. [less ▲]

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See detailInvestigation on the use of foamed plastic waste as natural aggregates replacement in lightweight mortar
Coppola, Bartolomeo ULg; Courard, Luc ULg; Michel, Frédéric et al

in Composites : Part B, Engineering (2016), 99

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See detailAn investigation on the use of GBT for the study of profiles with branched cross section
Degée, Hervé ULg; Boissonnade, N.

in Proceedings of the Fourth International Conferences on Coupled Instabilities in Metal Structures (2004)

This paper presents a formulation allowing the application of generalised beam theory (GBT) to the analysis of thin-walled members with branched open cross section. It is then applied to a simple example ... [more ▼]

This paper presents a formulation allowing the application of generalised beam theory (GBT) to the analysis of thin-walled members with branched open cross section. It is then applied to a simple example and compared with results obtained by the use of classical FE-models (beam elements or shell elements). [less ▲]

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See detailAn investigation on thermal performance of a low cost apartment in hot humid climate of Danang
Nguyen, Anh Tuan ULg; Reiter, Sigrid ULg

in Energy and Buildings (2012), 47

Low cost apartment has recently become one of the essential state policies to deal with rapid urbanisation and population boom in Vietnam. Thermal performance of a low cost apartment in Danang was ... [more ▼]

Low cost apartment has recently become one of the essential state policies to deal with rapid urbanisation and population boom in Vietnam. Thermal performance of a low cost apartment in Danang was examined using building simulation approach. The simulated results created by COMFIE were first calibrated by comparing them with measured data. The statistical indicators CV(RMSE) and NMBE as well as linear regression analysis were applied to assess the calibration. The calibrated model was then used to perform whole year simulations in which various ventilation and design strategies were applied. Thermal comfort potentials of these strategies were graphically defined by Brager’s adaptive comfort model from which the efficiency of each strategy was quantitatively determined. In the present paper, details of the calibration approach, assessment of simulated results and comparison of the findings were discussed. Results of these analyses revealed many notable findings which are in good agreement with those obtained from other publications. The limitation and recommendations for further study are also outlined. [less ▲]

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See detailInvestigation structurale par RMN 2D appliquée à l’analyse d’oligo- et poly-saccharides
Goffin, Dorothée ULg

Scientific conference (2008)

Dans cet exposé, diverses expériences 2D sont décrites et appliquées à l'analyse structurale d'oligosaccharides de structures proches. L'apport de chaque type d'expérience et les informations obtenues ... [more ▼]

Dans cet exposé, diverses expériences 2D sont décrites et appliquées à l'analyse structurale d'oligosaccharides de structures proches. L'apport de chaque type d'expérience et les informations obtenues sont mises en évidence afin de déterminer à la fois l'anomérie, le type de résidu et de liaisons ainsi que leur séquence. [less ▲]

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See detailInvestigational insulin secretagogues for type 2 diabetes.
SCHEEN, André ULg

in Expert opinion on investigational drugs (2016), 25(4), 405-22

INTRODUCTION: Insulin secretory defects are a key feature in the pathophysiology of type 2 diabetes (T2D). Classical insulin-secreting agents such as sulfonlyureas stimulate insulin secretion independent ... [more ▼]

INTRODUCTION: Insulin secretory defects are a key feature in the pathophysiology of type 2 diabetes (T2D). Classical insulin-secreting agents such as sulfonlyureas stimulate insulin secretion independent of glucose and cause hypoglycemia. Despite the advantages offered by incretin-based therapies, there is still a medical need for developing new insulin secretagogues for treating T2D. AREA COVERED: This article discusses: the new advances in the field of incretin-based therapies, glucokinase (GK) activators, free fatty acid receptor (FFAR) or G protein-coupled receptor (GPR) agonists (GPR40, GPR119, GPR120), imeglimin and some other insulin secretagogues with diverse mechanisms of action still in preclinical development. EXPERT OPINION: New insulin secretagogues should offer major advantages over sulfonylureas and gliptins. The challenge is to avoid uncontrolled insulin secretion and minimize the risk of hypoglycemia, to protect cells from progressive loss of mass and function for a better durability of glucose control, and to offer a good safety profile. Numerous approaches are in development. However, it is too early to decide whether one new pharmacological class will emerge as a clinically useful insulin secretagogue in the near feature. [less ▲]

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See detailInvestigations around an unrecognized genre: case study on speech captions in private tombs
Motte, Aurore ULg

Conference (2016, May 05)

Since the Old Kingdom, speech captions, generally known as “Reden und Rufe”, are found in the decorative program of private tombs. These captions are dialogs between workers in the “daily life” scenes ... [more ▼]

Since the Old Kingdom, speech captions, generally known as “Reden und Rufe”, are found in the decorative program of private tombs. These captions are dialogs between workers in the “daily life” scenes. They appear in several topics, such as fishing, butchery, crafts, ... Quite surprisingly, they have never been studied exhaustively since their first mention in 1918 in Egyptological literature. My first goal is twofold: to show precisely where and when they are found, and what exactly defines “Reden und Rufe” as a genre. Besides, a chronological scope of nearly 2,300 years allows me to highlight diachronic, diatopic, and diastratic variations. It is particularly evident in New Kingdom and Late Period tombs, where “Égyptien de Tradition” features are found next to “vernacular” ones. It has long been taken for granted, incorrectly, that these speeches were written in an idiom very close to colloquial. This first comprehensive study aims to determine which state(s) of language is/are used. [less ▲]

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See detailInvestigations of migraine
Nappi, G.; Sandrini, G.; Schoenen, Jean ULg

in Ekbom, K. (Ed.) Migraine in General Practice: basic concepts (1993)

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See detailInvestigations of the GCxGC-HRMS coupling
Focant, Jean-François ULg; Patterson Jr

Conference (2010, June)

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See detailInvestigations of typical stellar spectra with high dispersion. I. Table of lines in α Cygni.
Struve, Otto; Swings, Polydore ULg

in Astrophysical Journal (1941), 94

This paper contains a new table of wave lengths of absorption lines in the spectrum of α Cygni between λ 3862 and λ 6590.

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See detailInvestigations on a Level Set based approach for the optimization of flexible components in multibody systems with a fixed mesh grid
Tromme, Emmanuel ULg; Bruls, Olivier ULg; Van Miegroet, Laurent ULg et al

in Proceedings of The 6th Asian Conference on Multibody Dynamics: Shanghai (China), 26-30 aout 2012 (2012, August)

This paper considers the optimization of flexible components in mechanical systems thanks to a "fully integrated" optimization method which includes a flexible multibody system simulation based on ... [more ▼]

This paper considers the optimization of flexible components in mechanical systems thanks to a "fully integrated" optimization method which includes a flexible multibody system simulation based on nonlinear finite elements. This approach permits to better capture the effects of dynamic loading under service conditions. This process is challenging because most state-of-the-art studies in structural optimization have been conducted under (quasi-)static loading conditions or vibration design criteria and also because this ``fully integrated" optimization method is not a simple extension of static optimization techniques. The present paper proposes an approach based on a Level Set description of the geometry. This method leads to an intermediate level between shape and topology optimizations. Gradient-based optimization methods are adopted for their convergence speed. Numerical applications are conducted on the optimization of a connecting rod of a reciprocating engine with cyclic dynamic loading to show the feasibility and the promising results of this approach. [less ▲]

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See detailInvestigations on Both Chemical Composition and Insecticidal Activities on Essential Oils of Vepris heterophylla (Rutaceae) from Two Localities of Northern Cameroon Towards Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae)
Ngamo, Tinkeu L.S.; Noudjou, W.Félicité; Ngassoum, Martin B. et al

in Research Journal of Biological Sciences (2007), 2(1), 57-61

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See detailInvestigations on Cationic Exchange Capacity and Unused Bed Zone according to operational conditions in a Fixed Bed Reactor for water lead removal by a natural zeolite.
Fanfan, Pierre Naïder; Mabon, Nicolas; Thonart, Philippe ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2006), 10(2), 93-99

Detailed reference viewed: 152 (3 ULg)