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See detailIntegrated backscatter for the in vivo quantification of supraphysiological vitamin D(3)-induced cardiovascular calcifications in rats.
Roosens, Bram; Droogmans, Steven; Hostens, Jeroen et al

in Cardiovascular Toxicology (2011), 11(3), 244-52

Cardiovascular calcifications are frequently found in the aging population and are independent predictors of future cardiovascular events. Integrated backscatter (IB) of ultrasound reflectivity can easily ... [more ▼]

Cardiovascular calcifications are frequently found in the aging population and are independent predictors of future cardiovascular events. Integrated backscatter (IB) of ultrasound reflectivity can easily quantify calcifications. For this purpose, 30 male Wistar rats received 25,000 IU/kg/day of vitamin D(3) (group 1, n = 8), 18,800 IU/kg/day (group 2, n = 8), or injections with the vehicle only (group 3, n = 14), for 10 weeks. Echocardiographic calibrated IB (cIB) was measured and calculated at baseline and after 10 weeks, followed by ex vivo micro-CT and histopathology of the aortic valve, ascending aorta, and myocardium. After 10 weeks, the mean cIB value of the aortic valve was significantly higher for vitamin D(3)-dosed animals compared to controls. The mean cIB value of the ascending aorta and the myocardium was also significantly higher in group 1 compared to group 3. In vivo IB results were confirmed by ex vivo micro-CT and histopathology. In conclusion, IB is a non-ionizing, feasible, and reproducible tool to quantify cardiovascular calcifications in an in vivo rat model. The integration of IB in the standard echocardiographic examination for the quantification of cardiovascular calcifications could be useful for serial evaluation of treatment efficacy and for prognosis assessment. [less ▲]

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See detailIntegrated bio-chemostratigraphical correlations and climatic evolution across the Danian-Selandian boundary at low latitudes
Storme, Jean-Yves ULg; Steurbaut, Etienne; Devleeschouwer, Xavier et al

in Palaeogeography, Palaeoclimatology, Palaeoecology (2014), 414

Detailed reference viewed: 15 (4 ULg)
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See detailIntegrated biological control of crown rot of bananas with Candida oleophila strain O, calcium chloride and modified atmosphere
de Lapeyre de Bellaire, Luc; Lassois, Ludivine ULg; Bastiaanse, Héloïse ULg et al

in Borja; Nogales; Orrantia (Eds.) et al Memories of 18th Reuniao international ACORBAT meeting (2008)

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See detailIntegrated care pathways for airway diseases (AIRWAYS-ICPs).
Bousquet, J.; Addis, A.; Adcock, I. et al

in The European respiratory journal (2014), 44(2), 304-23

The objective of Integrated Care Pathways for Airway Diseases (AIRWAYS-ICPs) is to launch a collaboration to develop multi-sectoral care pathways for chronic respiratory diseases in European countries and ... [more ▼]

The objective of Integrated Care Pathways for Airway Diseases (AIRWAYS-ICPs) is to launch a collaboration to develop multi-sectoral care pathways for chronic respiratory diseases in European countries and regions. AIRWAYS-ICPs has strategic relevance to the European Union Health Strategy and will add value to existing public health knowledge by: 1) proposing a common framework of care pathways for chronic respiratory diseases, which will facilitate comparability and trans-national initiatives; 2) informing cost-effective policy development, strengthening in particular those on smoking and environmental exposure; 3) aiding risk stratification in chronic disease patients, using a common strategy; 4) having a significant impact on the health of citizens in the short term (reduction of morbidity, improvement of education in children and of work in adults) and in the long-term (healthy ageing); 5) proposing a common simulation tool to assist physicians; and 6) ultimately reducing the healthcare burden (emergency visits, avoidable hospitalisations, disability and costs) while improving quality of life. In the longer term, the incidence of disease may be reduced by innovative prevention strategies. AIRWAYSICPs was initiated by Area 5 of the Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing. All stakeholders are involved (health and social care, patients, and policy makers). [less ▲]

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See detailIntegrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen
Emmanuel, Noémie ULg; Mendoza Gallego, Carlos ULg; Lismont, Marjorie ULg et al

Poster (2016, December 08)

Development of photochemistry in macroscopic batch reaction vessels is hampered due to inherent limitations: light penetration remains superficial, resulting in inhomogeneous irradiation and hence to side ... [more ▼]

Development of photochemistry in macroscopic batch reaction vessels is hampered due to inherent limitations: light penetration remains superficial, resulting in inhomogeneous irradiation and hence to side-reactions or product degradation due to overexposure. The recent implementation of photochemical processes in microreactors under continuous-flow conditions appeared to be much more powerful than its batch analogue in terms of irradiation efficiency and light penetration. Furthermore, the fine control of residence time ensures an accurate control of the irradiation time, avoiding side-reactions and degradation. The photooxidation of (L)-methionine with singlet oxygen using Rose Bengal as a sensitizer was successfully implemented in a microreactor setup and led to total and selective conversion into methionine sulfoxide, an important building block for the organic synthesis of peptides or functionalized amino acid. The reaction was performed in 2 min while the same reaction in batch took 2h. [less ▲]

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See detailIntegrated continuous flow photoreactors: Photooxidation of (L)-methionine with singlet oxygen
Emmanuel, Noémie ULg; Mendoza Gallego, Carlos ULg; Lismont, Marjorie ULg et al

Poster (2016, October 13)

Development of photochemistry in macroscopic batch reaction vessels is hampered due to inherent limitations: light penetration remains superficial, resulting in inhomogeneous irradiation and hence to side ... [more ▼]

Development of photochemistry in macroscopic batch reaction vessels is hampered due to inherent limitations: light penetration remains superficial, resulting in inhomogeneous irradiation and hence to side-reactions or product degradation due to overexposure. The recent implementation of photochemical processes in microreactors under continuous-flow conditions appeared to be much more powerful than its batch analogue in terms of irradiation efficiency and light penetration. Furthermore, the fine control of residence time ensures an accurate control of the irradiation time, avoiding side-reactions and degradation. The photooxidation of (L)-methionine with singlet oxygen using Rose Bengal as a sensitizer was successfully implemented in a microreactor setup and led to total and selective conversion into methionine sulfoxide, an important building block for the organic synthesis of peptides or functionalized amino acid. The reaction was performed in 20 min while the same reaction in batch took 2h. [less ▲]

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See detailIntegrated control and structural analysis of DFIG wind turbines using a monolithic approach
Chen, Qiongzhong ULg; D'Ambrosio, Flavio; Defourny, Michel et al

in Proceedings of the European Wind Energy Conference and Exhibition 2012 (EWEA 2012) (2012, April)

Design of wind turbines requires the coupled analysis among the mechanical, control and aerodynamic subsystems. Different from previous research, which either uses a complicated mechanical model with a ... [more ▼]

Design of wind turbines requires the coupled analysis among the mechanical, control and aerodynamic subsystems. Different from previous research, which either uses a complicated mechanical model with a simple control system model, or vice versa, this paper studies the coupling of subsystems’ dynamics using a high-fidelity aeroelastic model of wind turbine and a detailed analytical model of control generating systems. A monolithic time integration approach is applied so that better numerical accuracy and stability are achieved. Control strategies on power optimization are discussed taking into account the influence of structural flexibility. Simulation examples are given on both stable and turbulent wind situation. [less ▲]

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See detailIntegrated control of crown rot of banana with Candida oleophila strain O, calcium chloride and modified atmosphere packaging
Bastiaanse, H.; de Lapeyre de Bellaire, Luc; Lassois, Ludivine ULg et al

in Biological Control (2010), 53

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See detailAn integrated control-structure design for manipulators with flexible links
Bastos Jr., Guaraci; Bruls, Olivier ULg

in IFAC-PapersOnLine (2015), 48(11), 156-161

Integrated optimization techniques for mechatronic systems aim at designing simultaneously the trajectory, the control system and the mechanical structure in order to minimize a performance index. The key ... [more ▼]

Integrated optimization techniques for mechatronic systems aim at designing simultaneously the trajectory, the control system and the mechanical structure in order to minimize a performance index. The key advantage of such an integrated approach is the capability to search in a wide design space, to account for many dynamic couplings in an early design stage and to avoid simplifying assumptions which would induce a suboptimal design. This work considers that technique for robotic manipulators with flexible links. It is known that a exible multibody system is often non-minimum phase, here, no restriction is imposed to avoid it. This allows a free choice of the optimization process to select a lighter weight controlled system. Furthermore, the amplitudes of the non-actuated degrees-of-freedom should be reduced in order to limit bodies deformation. The mechanical model is derived using a nonlinear finite element method, which is a useful approach to represent systems with elastic bodies. An optimal control problem is considered to perform that integrated analysis and its time dicretization relies the direct transcription method. [less ▲]

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See detailIntegrated detection and correction of outliers in a random regression test-day model
Mayeres, Patrick; Gillon, Alain ULg; Gengler, Nicolas ULg

in INTERBULL Bulletin (2003), 31

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See detailIntegrated dynamical models of down-the-hole percussive drilling
Depouhon, Alexandre ULg

Doctoral thesis (2014)

Due to the overall process complexity, studies about percussive drilling usually focus on a limited set of the subprocesses underlying it, e.g., the hammer thermodynamics or the interaction between the ... [more ▼]

Due to the overall process complexity, studies about percussive drilling usually focus on a limited set of the subprocesses underlying it, e.g., the hammer thermodynamics or the interaction between the bit and the rock. Following this paradigm, the assessment of the process performance is typically performed by considering a single percussive activation and a single interaction cycle between the bit and the rock, from arbitrary initial conditions. The need for an integrated approach to evaluate drilling performance, based on the dynamical interaction of the subprocesses underlying drilling, is evident. Such an approach requires simplified models, however, as the computational cost associated with full scale models is simply unbearable. In this thesis, three dynamical integrated models are proposed and a preliminary analysis is conducted for a reference configuration and around it. The models couple three modules that represent: (i) the dynamics of the mechanical system, (ii) the interaction between the bit and the rock, and (iii) the activation of the mechanical system. For each module, simple representations are considered; of particular importance is the bit/rock interaction model which is a generalization to repeated interactions of experimental evidence observed for a single interaction. In the first model, the dynamics of a rigid bit is cast into a drifting oscillator and the activation modeled as a periodic impulsive force. The second and third models account for the dynamics of the piston and the activation results from the impact of the piston on the bit. They are respectively based on elastic and rigid representations of the two bodies. In the rigid model, analytical results of wave propagation in thin rods are used to represent the contact interaction between the piston and the bit. In the elastic model, wave propagation is resolved. Their preliminary analysis has revealed the occurrence of complex dynamical responses in the space of parameters. Expected trends are recovered around a reference configuration corresponding to a low-size hammer, with an increase of the rate of penetration with the feed force and the percussive frequency. The latter is seen to have a strong influence on the rate of penetration. Interestingly, our analyses show that when the activation period has the same order of magnitude as the timescale associated with the bit/rock interaction, a lower power consumption is observed, indicating a possible resonance phenomenon in the drilling system. Also, the predictions of the rigid model are shown to be in good agreement with the ones of the elastic model, in the explored range of parameters. Given the piecewise linear nature of the proposed models, dedicated numerical tools have been developed to conduct their analysis. As such, the thesis proposes a high-order time integration scheme for structural dynamics as well as a novel framework to evaluate the accuracy of such schemes, and a root-solving module to perform event-detection for coupling with event-driven integration strategies. Specific to the framework is the account for both structural damping and external forcing in the evaluation of the scheme order of accuracy. Specific to the root-solving module is the forcing of event occurrence in the localization procedure. [less ▲]

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See detailIntegrated farming systems in Kinshasa (DRC) Diversity of agricultural practices
Mafwila Kinkela, Patrick ULg; Bindelle, Jérôme ULg; WILLEMS, E, Emilie et al

Poster (2014, February 07)

In Kinshasa in the Democratic Republic of Congo, integrated farming of livestock and fish farming is little documented while it is an interesting way of ecological intensification systems. After ... [more ▼]

In Kinshasa in the Democratic Republic of Congo, integrated farming of livestock and fish farming is little documented while it is an interesting way of ecological intensification systems. After identifying the density of fish ponds in the territory of the city using satellite images, about 200 farms with at least one pond and located in 2 in peri-urban and rural areas were surveyed to characterize the practical integration of the agricultural system. The preliminary results in one of the valleys indicate that the practice of agriculture in synergy with the pig and fish farming is a common practice although flow of components are still insufficiently integrated and some of them are not optimized . The fish - pig farming associations with or without vegetable production are 44 % of the sample. The identification of flow on farms showed that the manure of pigs is mainly used for crops (51%) or sold (28%), while a small part is used to fertilize the ponds. This may be explained by the predominant share of income (67%) devoted to vegetable production while sludge of ponds is rarely used to fertilize area of vegetable production. Residues of vegetable crops are rarely used to feed pigs and fish because of their limited availability. Feeding pigs and fish is based primarily on agro-industrial by-products such as wheat bran (81%) and the spent brewery grains (62%) and forages (62%). The presentation will analyze the results obtained in the three sites visited and outline opportunities for improvement. [less ▲]

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See detailIntegrated field assessment of contaminant fate and transport in the unsaturated and saturated zone
Fernandez de Vera, Natalia ULg; Peña Hernandez, Juan Angel ULg; Jamin, Pierre ULg et al

Poster (2013, April 22)

In the poster, a multidisciplinary methodology is presented with the aim of characterizing fate and transport of pollutants in the vadose and the saturated zone of industrial sites. The methodology used ... [more ▼]

In the poster, a multidisciplinary methodology is presented with the aim of characterizing fate and transport of pollutants in the vadose and the saturated zone of industrial sites. The methodology used for the vadose zone consist in the combination of the Vadose Monitoring System, cross-hole and surface geophysics at a local scale. For saturated zone studies, the approach consist in the chemical and isotopic analysis of the various contaminants present on site at regional scale. [less ▲]

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See detailIntegrated flood risk analysis for assessing flood protection strategies
Ernst, Julien ULg; Dewals, Benjamin ULg; Detrembleur, Sylvain ULg et al

in Tagelsir, Gasmelseid (Ed.) Handbook of Research on Hydroinformatics: Technologies Theories and Applications (2010)

The present chapter describes an end-to-end methodology for assessing flood protection strategies, including the whole methodological process from hydrological statistics to detailed 2D hydraulic ... [more ▼]

The present chapter describes an end-to-end methodology for assessing flood protection strategies, including the whole methodological process from hydrological statistics to detailed 2D hydraulic modelling, damage calculation and flood risk evaluation. This risk-based approach serves as a component of a decision-support system (DSS) developed in Belgium for identifying cost-effective flood management strategies in the context of climate change. The DSS accounts for both hydraulic and socio-economic parameters to quantify the benefits (in terms of avoided risk) and the cost of each strategy. Besides reviewing fundamentals of flood risk assessment, including the inundation model and main concepts related to flood risk, a consistent methodology for micro-scale flood risk analysis is presented in detail, combining complementary sources of GIS information such as high resolution and high accuracy land use database as well as socio-economic datasets. Finally a case study on a main tributary of river Meuse in Belgium is described. [less ▲]

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See detailAn integrated framework for forecasting travel behavior using Markov Chain Monte-Carlo simulation and profile Hidden Markov Models
Saadi, Ismaïl ULg; El Saeid Mustafa, Ahmed Mohamed ULg; Teller, Jacques ULg et al

in Proceedings of the 95th Annual Meeting of the Transportation Research Board (2016)

Recent advances in agent-based micro-simulation modelling have further underlined the importance of a thorough full synthetic population procedure to guarantee a correct characterization of the true ... [more ▼]

Recent advances in agent-based micro-simulation modelling have further underlined the importance of a thorough full synthetic population procedure to guarantee a correct characterization of the true population. We propose an integrated approach including Markov Chain Monte Carlo (MCMC) simulation and profiling based methods to catch the complexity and the diversity of agents of the true population through representative micro samples. The population synthesis method is capable of building the joint distribution of a given population with its corresponding marginal distributions (e.g. age, gender, socio-professional status etc.) using complete, partial conditional probabilities or both of them at the same time. Particularly, the estimation of socio-demographic variables and characterization of daily activity-travel patterns are included within the framework. Data stemming from the 2010 Belgian Household Daily Travel Survey (BELDAM) are used to calibrate the modelling framework. We illustrate that this framework catches in an efficient way the behavioral heterogeneity of travelers. Furthermore, we show that the proposed framework is adequately adapted to build large scale micro-simulation scenarios of transportation and urban systems. [less ▲]

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See detailAn integrated history of paleoearthquakes along the North Anatolian Fault (Turkey)
Hubert, Aurelia ULg; Vanneste, Kriss; Avsar, U.

in Abstracts with Programs - Geological Society of America (2010, October)

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See detailIntegrated logic circuits using single-atom transistors
Mol, J.; Verduijn, J.; Levine, R. D. et al

in Proceedings of the National Academy of Sciences of the United States of America (2011), 108(34), 13969-13972

Detailed reference viewed: 24 (1 ULg)