Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
See detailIs hepatitis E virus zoonotic?
Thiry, Damien ULg

Conference (2011, December)

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailIs HIF-1alpha a pro- or an anti-apoptotic protein?
Piret, Jean-Pascal; Mottet, Denis ULg; Raes, Martine et al

in Biochemical Pharmacology (2002), 64(5-6), 889-92

Hypoxia-inducible factor-1 (HIF-1) is the major transcription factor specifically activated by hypoxia. It induces the expression of different genes whose products play an adaptive role for hypoxic cells ... [more ▼]

Hypoxia-inducible factor-1 (HIF-1) is the major transcription factor specifically activated by hypoxia. It induces the expression of different genes whose products play an adaptive role for hypoxic cells and tissues. Besides these protective responses, HIF-1 and/or hypoxia have also been shown to be either anti-apoptotic or pro-apoptotic, according to the cell type and experimental conditions. More severe or prolonged hypoxia rather induces apoptosis that is, at least in part, initiated by the direct association of HIF-1alpha and p53 and p53-induced gene expression. On the other hand, HIF-1alpha dimerized with ARNT, as an active transcription factor, can protect cells from apoptosis induced by several conditions. This review is aimed to describe the different mechanisms that account for these opposite effects of HIF-1alpha. [less ▲]

Detailed reference viewed: 24 (3 ULg)
Full Text
See detailIs hypoxia-inducible factor 1 an actor in migraine pathogenesis?
TRUONG, Julie ULg; Mascetti, Laura; Schoenen, Jean ULg et al

Poster (2009, May)

Detailed reference viewed: 29 (0 ULg)
Full Text
Peer Reviewed
See detailIs IL-6 capable to modify chondrocyte metabolism ?
Henrotin, Yves ULg; Labasse, A; Jaspar, JM et al

in Clinical Rheumatology (1996), 15

Detailed reference viewed: 9 (2 ULg)
Full Text
Peer Reviewed
See detailIs individual consistency in body mass and reproductive decisions linked to individual specialization in foraging behavior in a long-lived seabird?
Dehnhard, Nina; Eens, Marcel; Sturaro, Nicolas ULg et al

in Ecology and Evolution (2016)

Individual specialization in diet or foraging behavior within apparently generalist populations has been described for many species, especially in polar and temperate marine environments, where resource ... [more ▼]

Individual specialization in diet or foraging behavior within apparently generalist populations has been described for many species, especially in polar and temperate marine environments, where resource distribution is relatively predictable. It is unclear, however, whether and how increased environmental variability – and thus reduced predictability of resources – due to global climate change will affect individual specialization. We determined the within- and among-individual components of the trophic niche and the within-individual repeatability of d13C and d15N in feathers and red blood cells of individual female southern rockhopper penguins (Eudyptes chrysocome) across 7 years. We also investigated the effect of environmental variables (Southern Annular Mode, Southern Oscillation Index, and local sea surface temperature anomaly) on the isotopic values, as well as the link between stable isotopes and female body mass, clutch initiation dates, and total clutch mass. We observed consistent red blood cell d13C and d15N values within individuals among years, suggesting a moderate degree of within-individual specialization in C and N during the prebreeding period. However, the total niche width was reduced and individual specialization not present during the premolt period. Despite significant interannual differences in isotope values of C and N and environmental conditions, none of the environmental variables were linked to stable isotope values and thus able to explain phenotypic plasticity. Furthermore, neither the within-individual nor among-individual effects of stable isotopes were found to be related to female body mass, clutch initiation date, or total clutch mass. In conclusion, our results emphasize that the degree of specialization within generalist populations can vary over the course of 1 year, even when being consistent within the same season across years. We were unable to confirm that environmental variability counteracts individual specialization in foraging behavior, as phenotypic plasticity in d13C and d15N was not linked to any of the environmental variables studied. [less ▲]

Detailed reference viewed: 15 (3 ULg)
Full Text
Peer Reviewed
See detailIs isokinetic eccentric exercise dangerous for the heart?
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; LAURENT, Terry ULg et al

in Isokinetics & Exercise Science (2014), 22(2), 131-136

BACKGROUND: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in order ... [more ▼]

BACKGROUND: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in order to perform these very intensive exercises; otherwise an acute myocardial dysfunction could theoretically appear in predisposed patients. OBJECTIVE: Our study aimed to observe the cardiovascular impact of a maximal intense isokinetic eccentric exercise performed by a population of sedentary young men. METHODS: Resting and post-exercise (just after, 3 hours and 24 hours after the exercise) blood samples were taken from 12 young male sedentary healthy subjects. These subjects performed an intense maximal eccentric isokinetic exercise of the quadriceps muscle.We evaluated markers of cardiovascular risk (troponin I, highly sensitive troponin T, NT-proBNP,myoglobin), of inflammation (hsCRP) and of oxidative stress (myeloperoxydase, lipidic peroxides, reduced and oxidized glutathione). RESULTS: The following observations were made: no significant increase in cardiac (NT-proBNP, troponins) or inflammation (hsCRP) biomarkers; a significant increase in myoglobin, myeloperoxidase, lipidic peroxides, oxidised glutathione just after the exercise. CONCLUSIONS: No modification in cardiac biomarkers were observed after the maximal eccentric isokinetic exercise. We were thus able to prove that the exercise could be performed without any risk to cardiac function in young sedentary subjects. However, a significant level of oxidative stress was induced by this exercise. [less ▲]

Detailed reference viewed: 80 (15 ULg)
Full Text
Peer Reviewed
See detailIs isokinetic exercise dangerous for the heart?
Le Goff, Caroline ULg; Kaux, Jean-François ULg; Cavalier, Etienne ULg et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(suppl. 1 No. 2), 457

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in ... [more ▼]

INTRODUCTION: Very strenuous exercises can be performed on an isokinetic dynamometer in order to evaluate the resistance to fatigue of different muscular groups. Good cardiac function is necessary in order to perform these very intensive exercises; otherwise an acute myocardial dysfunction could theoretically appear in predisposed patients. PURPOSE: Our study aimed to observe the cardiovascular impact (by biological point of view) of maximal intense isokinetic eccentric and concentric protocols performed by a population of sedentary young men. METHOD: Resting (T0) and post-exercise (just after (T1), 3 hours (T2) and 24 hours after the exercise (T3)) blood samples were taken in 2 populations of young sedentary men: 12 subjects (22.5±1.15 yo) for the eccentric protocol and 18 subjects (22.4±2.6 yo) for the concentric protocol. These subjects performed an intense maximal isokinetic exercise of the quadriceps muscles involving 30 knee flexions–extensions for each leg. We evaluated markers of cardiovascular risk (highly sensitive troponin T (hs-TnT), N-Terminal Brain natriuretic peptide (NT-proBNP), myoglobin (MYO)), of inflammation (highly sensitive C-reactive protein (hsCRP)), muscle damage (creatine kinase (CK)) and of oxidative stress (myeloperoxidase (MPO), lipidic peroxides (POXL), reduced (GSH) and oxidised glutathione (GSSG)). Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: All the physiological parameters measured presented statistically significant changes. For the eccentric exercise, no significant modification in cardiac (NT-proBNP, hs-TNT) and inflammation (hsCRP) biomarkers was observed. However, a significant increase for CK (T3), MYO (T2), MPO (T1), POXL (T1), GSSG (T3) and ratio GSH/GSSG (T2-T3) was shown. For the concentric exercise, the results showed significant increases for the CK (T1-T2-T3), MYO (T1-T2), GSH/GSSG (T1). Evolutionary trends were also observed for the following biomarkers: NT-proBNP (T1-T2-T3), MPO (T2), and GSSG (T4). DISCUSSION and CONCLUSIONS: No modification in cardiac biomarkers was observed after the maximal eccentric isokinetic exercise but some variations can be observed for these biomarkers after the concentric exercise. However, these changes do not exceed the reference values in healthy subjects. We were thus able to prove that the exercise could be performed without any risk to cardiac function in young sedentary subjects. Nevertheless, a significant level of oxidative stress was induced by both exercises. [less ▲]

Detailed reference viewed: 35 (4 ULg)
Full Text
See detailIs it ever appropriate to stop anti-tumor necrosis factor in a stable patient?
LOUIS, Edouard ULg

in Rubin, David, T.; Friedman, Sonia; Farraye, Francis A. (Eds.) Curbside Consultation in IBD: 49 Clinical Questions, Second Edition (2013)

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailIs it necessary to change the classification of ß-lactamases?
Frère, Jean-Marie ULg; Galleni, Moreno ULg; Bush, Karen et al

in Journal of Antimicrobial Chemotherapy (2005), 55(6), 1051-1053

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailIs it possible for large herds to graze while keeping a high milk yield level? The experience of two Belgian dairy farms.
Lessire, Françoise ULg; Hornick, Jean-Luc ULg; Dufrasne, Isabelle ULg

in van den Pol-van Dasselaer, Agnes; Aarts, H.F.M; De Vliegher, Alex (Eds.) et al Grassland and forages in high output dairy farming systems (2015, June 15)

Grazing is more and more abandoned because of increasing size of herds and automation of herd management (e.g. automatic milking system – AMS). In this context, this study aims to evaluate milk production ... [more ▼]

Grazing is more and more abandoned because of increasing size of herds and automation of herd management (e.g. automatic milking system – AMS). In this context, this study aims to evaluate milk production and composition of 2 large Belgian dairy herds equipped with AMS during winter and summer. These herds were followed over 2 years. At grazing, 30% of the offered feed was grass. Milk production in both herds was similar in summer and winter (30.2 ± 7.14 vs 29.7 ± 7.8 ± in Herd 1 and 26.9 ± 0.8 vs 26.4 ± 0.8 in Herd 2) while their milk composition differed. In conclusion, it is possible for grazing to be preserved even in large herds without impacting noticeably on the herd performance. [less ▲]

Detailed reference viewed: 29 (5 ULg)
Full Text
See detailIs It Possible to Define a European Total Merit Index?
Vanderick, Sylvie ULg; Faux, Pierre ULg; Gengler, Nicolas ULg

in Interbull Bulletin (2012), 44

Developing a common European bull list is an objective of the PROTEJE (PROduction Traits European Joint Evaluation) workgroup started in 2001 as an initiative of the European Holstein herdbooks. Six Total ... [more ▼]

Developing a common European bull list is an objective of the PROTEJE (PROduction Traits European Joint Evaluation) workgroup started in 2001 as an initiative of the European Holstein herdbooks. Six Total Merit Indexes were compared to define a common breeding goal across Europe. A principal component analysis was used to observe the direction of the largest common variation among the studied Total Merit Indexes. Results showed that the considered indexes had a lot in common. The first principal component explained 86% of the total variation. Based on previous researches establishing combined proofs on a European phantom scale for most traits and trait groups and using a multiple regression for this European Total Merit Index, relative emphases on production and functionality of 37% and on conformation of 26% could be established. [less ▲]

Detailed reference viewed: 45 (14 ULg)
Full Text
See detailIs It Possible to Define a European Total Merit Index? (Presentation for the PROTEJE group)
Vanderick, Sylvie ULg; Faux, Pierre ULg; Gengler, Nicolas ULg

Conference (2011, August 27)

Possibility of having one common european list of bulls was investigated by principal component analysis (PCA) on 6 european nationals total merit indexes (TMI). Results showed that a european TMI can ... [more ▼]

Possibility of having one common european list of bulls was investigated by principal component analysis (PCA) on 6 european nationals total merit indexes (TMI). Results showed that a european TMI can never completely replace national TMIs, since they represent local differences. [less ▲]

Detailed reference viewed: 19 (6 ULg)
See detailIs it possible to detect bovine treated with BST?
Bertozzi, C.; Portetelle, Daniel ULg; Mestdagt, M. et al

in Biotechnology in animal husbandry (2001)

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailIs it possible to improve communication around radiotherapy delivery: A randomized study to assess the efficacy of team training?
Liénard, Aurore; Delevallez, France; Razavi, Darius et al

in Radiotherapy & Oncology (in press)

Detailed reference viewed: 32 (12 ULg)
Full Text
Peer Reviewed
See detailIs it possible to improve radiotherapy team members’ communication skills. A randomized study assessing the efficacy of a 38h communications skills training program
GIBON, Anne-Sophie; MERCKAERT, Isabelle; LIENARD, Aurore et al

in Radiotherapy & Oncology (2013), 109(1), 170177

Background and purpose: Optimizing communication between radiotherapy team members and patients and between colleagues requires training. This study applies a randomized controlled design to assess the ... [more ▼]

Background and purpose: Optimizing communication between radiotherapy team members and patients and between colleagues requires training. This study applies a randomized controlled design to assess the efficacy of a 38-h communication skills training program. Material and methods: Four radiotherapy teams were randomly assigned either to a training program or to a waiting list. Team members’ communication skills and their self-efficacy to communicate in the context of an encounter with a simulated patient were the primary endpoints. These encounters were scheduled at the baseline and after training for the training group, and at the baseline and four months later for the waiting list group. Encounters were audiotaped and transcribed. Transcripts were analyzed with content analysis software (LaComm) and by an independent rater. Results: Eighty team members were included in the study. Compared to untrained team members, trained team members used more turns of speech with content oriented toward available resources in the team (relative rate [RR] = 1.38; p = 0.023), more assessment utterances (RR = 1.69; p < 0.001), more empathy (RR = 4.05; p = 0.037), more negotiation (RR = 2.34; p = 0.021) and more emotional words (RR = 1.32; p = 0.030), and their self-efficacy to communicate increased (p = 0.024 and p = 0.008, respectively). Conclusions: The training program was effective in improving team members’ communication skills and their self-efficacy to communicate in the context of an encounter with a simulated patient. Future study should assess the effect of this training program on communication with actual patients and their satisfaction. Moreover a cost-benefit analysis is needed, before implementing such an intensive training program on a broader scale. [less ▲]

Detailed reference viewed: 73 (21 ULg)
Full Text
Peer Reviewed
See detailIs it possible to improve residents breaking bad news skills? A randomised study assessing the efficacy of a communication skills training program
Liénard, A.; Merckaert, I.; Libert, Y. et al

in Psycho-oncology (2009, June), 18 (Suppl. 2)

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailIs it possible to improve residents breaking bad news skills? A randomised study assessing the efficacy of a communication skills training program
Liénard, A.; Merckaert, I.; Libert, Y. et al

in British Journal of Cancer (2010), 103

Detailed reference viewed: 21 (3 ULg)
Full Text
Peer Reviewed
See detailIs it possible to improve residents' breaking bad news skills in a simulated three-person consultation? A randomized study assessing the efficacy of a communicatin skills training program
Liénard, A.; Merckaert, I.; Libert, Y. et al

in Psycho-oncology (2010, May), 19(Suppl.2)(1-313), 96

Detailed reference viewed: 23 (0 ULg)