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See detailNo interest for a second close infiltration of platelet-rich plasma to treat upper patellar tendinopathies
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Buhler, Frédéric et al

in European Journal of Physical and Rehabilitation Medicine (2014, May), 50(Suppl. 1 to No. 3), 21639-002-

Background: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Background: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. The aim of this study was to evaluate whether 2 infiltrations of PRP proves more effective than a single treatment. Methods: Twenty patients suffering from jumper’s knee for over than 3 months were enrolled into the study and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. Conclusion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups after a follow-up period of 3 months. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. [less ▲]

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See detailNo Laughing Matter
Maiorano, Diego ULg

Article for general public (2013)

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See detailNo major month to month variation in free testosterone levels in aging mates. Minor impact on the biological diagnosis of 'andropause'
Tancredi, Annalisa ULg; Reginster, Jean-Yves ULg; Luyckx, Françoise ULg et al

in Psychoneuroendocrinology (2005), 30(7), 638-646

BACKGROUND: The measurement of bioavailable testosterone (BT) or free testosterone (FT) levels is currently considered the gold standard for the diagnosis of androgen deficiency in elderly men. While the ... [more ▼]

BACKGROUND: The measurement of bioavailable testosterone (BT) or free testosterone (FT) levels is currently considered the gold standard for the diagnosis of androgen deficiency in elderly men. While the impact of age on circulating testosterone levels (total, bioavailable and free) has been strongly documented, the existence of seasonal variations in testosterone levels remains debated. OBJECTIVE: We investigated whether seasonal variations in serum calculated free testosterone (cFT) levels may translate into variations in the prevalence of low testosterone levels. Diagnosis was on the basis of biochemical determinations and was cross-checked with the prevalence of clinical signs and symptoms of 'andropause', as assessed by the Androgen Deficiency in Aging Males (ADAM) questionnaire. METHODS: The study recruited 5028 men aged 50 years and over from September 2000 to January 2003. Their serum FT levels were assessed and they completed the French ADAM test. Men were considered eugonadal when cFT was > or =70 ng/l. The ADAM test was scored as described originally. The prevalence of 'andropause', diagnosed by the two methods, was compared throughout the year, on a month by month basis. RESULTS: The percentage of subjects with cFT levels below 70 ng/l increased significantly with age (P<0.001). Serum cFT levels (mean [SD]) varied significantly with the month of sampling (P<0.0001), the highest (88.1 [30.2] ng/l) and lowest (76.9 [28.0] ng/l) mean values occurring in April and in October, respectively. Conversely, the prevalence of testosterone deficiency (cFT<70 ng/l) reached a peak in October (45.7%) and a nadir in April (29.7%). Although the prevalence of 'andropause', based on the ADAM questionnaire, increased significantly with age (P<0.0001), no influence of the month of the year was noticed. CONCLUSIONS: Our results confirm a progressive age-related decline in FT levels. The monthly variations in serum FT values, observed throughout the year, do not show a major seasonal rhythm in elderly community-dwelling males, since the magnitude of the variations (<15%) remains marginal. This slight variation may, however, have an impact on the number of elderly men diagnosed with Partial Androgen Deficiency in Aging Males (PADAM). [less ▲]

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See detailThe NO Martian Nightglow observed with the SPICAM UV Spectrometer and comparison with a one-dimensional model.
Cox, Cédric ULg; Saglam, A.; Gérard, Jean-Claude ULg et al

Conference (2007, April)

Observations in the 108-317 nm wavelength range have been performed with the SPICAM ultraviolet spectrometer aboard the Mars Express (MEX) mission. SPICAM has observed the ultraviolet nightglow emission ... [more ▼]

Observations in the 108-317 nm wavelength range have been performed with the SPICAM ultraviolet spectrometer aboard the Mars Express (MEX) mission. SPICAM has observed the ultraviolet nightglow emission in the δ (190-240 nm) and γ (225-270 nm) bands of nitric oxide (Bertaux et al. 2005). This emission arises from the recombination between O(3P) and N(4S) atoms that are produced on the day side to form NO in the night side. We present a summary of the night limb observations performed during the MEX mission. In particular, we describe the variability of the brightness and peak altitude. We find that the altitude of maximum emission varies between 55 and 90 km and the brightness is in the range 0.2 to 4.5 kR. We compare these observations with the results of a chemical-diffusive atmospheric model which solves the continuity equation for O, N(4S) and NO continuity equation using the finite volume method on one dimensional grid. The eddy coefficient, whose value is very uncertain, is a free parameter adjusted to match the observational data. [less ▲]

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See detailNo performance reduction at the present northern edge of Ambrosia artemisiifolia L. invasion range
Ortmans, William ULg

Conference (2014, May 05)

Plant populations at range edges may exhibit reduction of performances and fitness. In the case of biological invasions, such a reduction could be associated with a slowing down of the spread and explain ... [more ▼]

Plant populations at range edges may exhibit reduction of performances and fitness. In the case of biological invasions, such a reduction could be associated with a slowing down of the spread and explain the non-naturalization of a species outside its present invasion range. Common ragweed (Ambrosia artemisiifolia L.) is an ideal model to investigate such processes, since it is invasive in France but not naturalized in northern countries, such as Belgium and the Netherlands. In this study, we test if the performances of ragweed populations vary among different invasion zones. Three populations were selected in each of four invasion zones in Western Europe: 1) French invasion area; 2) northern and 3) southern invasion edges; and 4) outside the invasion area (Belgium and Netherlands). Field performances (growth, reproduction, stress resistance) were recorded on 25 plants per population. Furthermore, the competition by the native flora was assessed around each plant. Generalized Linear Models were used to compare performance among invasion zones and populations, with competition as covariate. Regressions were also performed to assess the influence of climatic data on population performances. No evidence of decreasing performances was found at the edges of the invasion area, neither outside of it, suggesting that the invasion front has the potential to keep going northwards. Competition by native flora had a significant impact on stress resistance, but did not decrease reproduction or growth. These results are discussed in the light of other ongoing experiments in Belgium. [less ▲]

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See detailNo serologic evidence for emerging Schmallenberg virus infection in dogs (Canis domesticus)
Garigliany, Mutien-Marie ULg; Desmecht, Daniel ULg; Bayrou, Calixte ULg et al

in Vector Borne & Zoonotic Diseases (2013), 13(11), 1-4

Schmallenberg virus, a novel orthobunyavirus, is spreading among ruminants, especially sheep and cattle throughout Europe. To determine the risk for domestic dog infection, we conducted a survey among ... [more ▼]

Schmallenberg virus, a novel orthobunyavirus, is spreading among ruminants, especially sheep and cattle throughout Europe. To determine the risk for domestic dog infection, we conducted a survey among cases referred to the university Companion Animal Clinic to assess possible seroconversion. No evidence of transmission to dogs was detected. [less ▲]

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See detailNo significant effect of an "atraumatic" needle on incidence of post-lumbar puncture headache or traumatic tap.
Lenaerts, M.; Pepin, J. L.; Tombu, S. et al

in Cephalalgia : An International Journal of Headache (1993), 13(4), 296-7

We compared the incidence of post-lumbar puncture headache and of red blood cells in the first CSF sample (traumatic tap) in 35 inpatients punctured with a standard 20 G Yale needle and in 26 patients ... [more ▼]

We compared the incidence of post-lumbar puncture headache and of red blood cells in the first CSF sample (traumatic tap) in 35 inpatients punctured with a standard 20 G Yale needle and in 26 patients punctured with Sprotte's "atraumatic" needle. No significant difference was found between the two groups in incidence of headache or in frequency of traumatic taps. [less ▲]

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See detailNo simian Plasmodium detected in populations living in the equatorial rainy forest of the Democratic Republic of Congo
Mvumbi makaba, Dieudonné; Bobanga Lengu, Thierry; Kayembe Ntumba, Jean-Marie et al

Poster (2014, April 03)

Background Malaria remains the most deadly parasitic disease to date, especially in sub-Saharan Africa, which comprises the majority of cases collected per year. It has long been accepted that four ... [more ▼]

Background Malaria remains the most deadly parasitic disease to date, especially in sub-Saharan Africa, which comprises the majority of cases collected per year. It has long been accepted that four species of Plasmodium (P. falciparum, P. vivax, P. malariae and P. ovale) were responsible for the disease in humans. But quite recently, a fifth species, Plasmodium Knowlesi, has been identified as naturally infecting humans. Indeed, known for decades as naturally parasitizing the monkey Macaca fascicularis, P. knowlesi has long been confused, in terms of its evolutionary stage, with P. malariae or P. falciparum, which it resembles morphologically and it was not possible to properly differentiate them until the advent of molecular biology. To date, P. Knowlesi has only been identified in Southeast Asia and a similar phenomenon of natural transmission of simian plasmodium to humans has not been reported elsewhere. We therefore conducted this study to investigate the possible transmission of simian plasmodium to humans in populations living near the rainforest of the Democratic Republic of Congo (DRC) where several species of primates lives. Methods & Materials Three villages (Wenji-Secli, Bongonde, and Bolenge) in the Province of Ecuador (North-eastern DRC) were selected because of their geographical location. Blood samples spotted on filter paper were collected from 100 people randomly taken in each village. Two successive RT- PCR were performed. A first one using a single probe able to diagnose all plasmodium spp. and a second using four species-specific probes for the diagnosis of the four conventional human plasmodium species. Positivity in the first RT- PCR with negativity in the second RT- PCR would suggest the presence of plasmodium species other than the four conventional. Results P. falciparum was correctly identified in 44.6 % of samples. No other species of human plasmodium or not has been identified. Conclusion This preliminary study did not detect the presence of simian plasmodium in human populations living in the rainforest of the DRC. Studies with larger samples and with more advanced techniques should still be conducted. Keywords: Malaria, simian plasmodium, DR Congo [less ▲]

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See detailThe NO Venus nightglow: SPICAV observations and implications on transport in the lower thermosphere
Gérard, Jean-Claude ULg; Cox, Cédric ULg; Bertaux, J.-L.

Conference (2010, June 22)

A new set of 725 NO limb profiles has been analyzed. The profiles have been deconvolved and inverted to get volume emission rates. Updates mean VER peak altitude is 115 km, in excellent agreement with PV ... [more ▼]

A new set of 725 NO limb profiles has been analyzed. The profiles have been deconvolved and inverted to get volume emission rates. Updates mean VER peak altitude is 115 km, in excellent agreement with PV results obtained 30 years ago. The corresponding average vertical intensity is 1.2 kR. The altitude of emission occurs at a higher altitude near the bright spot region than at larger distances (by about 7 km). The location of the statistical bright spot is the same as observed with PV (that is shifted dawnward by 2 hrs and slightly south of AS point). The nightside mean vertical intensity is between 0.4 and 1.8 kR, which brackets the values derived from the limb profiles. These results, coupled with other airglow measurements, provide constraints on global atmospheric circulation and vertical transport [less ▲]

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See detailNO-CARRIER-ADDED (NCA) ARYL [F-18] FLUORIDES VIA THE NUCLEOPHILIC AROMATIC-SUBSTITUTION OF ELECTRON-RICH AROMATIC RINGS
DING, Y. S.; SHIUE, C. Y.; FOWLER, J. S. et al

in Journal of Fluorine Chemistry (1990), 48(2), 189-205

Nucleophilic aromatic substitution by [18F]fluoride ion has been demonstrated on rings containing electron donating groups in addition to the necessary electron withdrawing and leaving groups.

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See detailNo-carrier-added aryl [18F]fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings.
Ding, Y.-S.; Shiue, C.-Y.; Fowler, J. S. et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1989), 30

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See detailNo-carrier-added asymmetric synthesis of alpha-methyl-alpha-amino acids labelled with fluorine-18
Damhaut, Philippe; Lemaire, Christian ULg; Plenevaux, Alain ULg et al

in Tetrahedron (1997), 53(16), 5785-5796

Various [18F]fluoro aromatic α-methyl-L-amino acids 11 have been synthesized with high enantiomeric purity (ee > 97%). These new radiopharmaceuticals for Positron Emission Tomography (PET), potential ... [more ▼]

Various [18F]fluoro aromatic α-methyl-L-amino acids 11 have been synthesized with high enantiomeric purity (ee > 97%). These new radiopharmaceuticals for Positron Emission Tomography (PET), potential inhibitors of enzymatic functions, were regiospecifically labelled by nucleophilic substitution on trimethylammoniumbenzaldehyde triflate precursors 9. The [18F]fluoro aromatic aldehydes 12 obtained were easily converted to the corresponding [18F]fluorobenzyl halides [13 (X = 1)]. After alkylation of the lithium enolate of (2S,5S)-l-tert-Boc-2-tert-butyl-3,5-dimethyl-imidazolidin-4-one 2, the adducts were cleaved to give, after HPLC purification, various [18F]fluoro-α-methyl amino acid analogs with radiochemical yields of 10% (End of Bombardment, EOB) after a synthesis time of 120 min. The corresponding [19F]fluorinated amino acids 4 and [19F]fluoro intermediates were also prepared. [less ▲]

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See detailNo-carrier-added regioselective preparation of 6-[18F]fluoro-L-dopa
Lemaire, Christian ULg; Guillaume, Marcel ULg; Cantineau, Robert et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1990), 31(7), 1247-1251

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See detailNo-Carrier-Added Regioselective Preparation of 6-[18f]Fluoro-L-Dopa
Bozet, Claire ULg; Guillaume, Marcel; Cantineau, R. et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1990), 31(7), 1247-51

This paper describes the preparation of 6-[18F]fluoro-L-dopa by a no-carrier-added method based on the nucleophilic displacement of nitro groups of two commercially available substrates, 3,4-dimethoxy-2 ... [more ▼]

This paper describes the preparation of 6-[18F]fluoro-L-dopa by a no-carrier-added method based on the nucleophilic displacement of nitro groups of two commercially available substrates, 3,4-dimethoxy-2-nitrobenzaldehyde (nitroveratraldehyde) and 6-nitropiperonal. Fluorination was conducted in DMSO with fluorine-18 (18F) in the presence of the aminopolyether Kryptofix 222 and potassium carbonate. The condensation of the fluorinated aldehydes with phenyloxazolone and the subsequent hydrolysis with HI/P yield, after purification by HPLC, only the 6-(D, L) isomers. The racemic mixture (50/50) was resolved on an analytical scale chiral column. The method, which requires 100 min (EOB) to complete, produces 6-[18F]fluoro-L-dopa with a decay-corrected radiochemical yield of 10%, an enantiomeric purity greater than 99%, and a specific activity of 1.2 Ci/mumole. [less ▲]

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See detailNO2 and CO interaction with plasma treated Au-decorated MWCNTs: Detection pathways
Leghrib, R.; Llobet, E.; Felten, A. et al

in Procedia Chemistry (2009), 1(1), 931-934

Detailed reference viewed: 2 (0 ULg)