AUDIOSCRIPT and EPEL - courseware to help students learn at their own pace and to allow teachers to observe their competencies and learning strategies
Conference (1996, November)Detailed reference viewed: 6 (1 ULg)
The Audiospinal Reaction in Parkinsonian Patients Reflects Functional Changes in Reticular Nuclei
Delwaide, Paul ; PEPIN, Jean-Louis ; Maertens De Noordhout, Alain
in Annals of Neurology (1993), 33(1), 63-9
Audiospinal facilitation using the soleus H-reflex as a test was compared in 16 control subjects and 23 parkinsonian patients. In the patients, facilitation was significantly reduced during the 75 to 150 ... [more ▼]
Audiospinal facilitation using the soleus H-reflex as a test was compared in 16 control subjects and 23 parkinsonian patients. In the patients, facilitation was significantly reduced during the 75 to 150 msec after the conditioning stimulation. This reduction was seen bilaterally even in patients with a hemisyndrome. It was corrected by L-dopa but not by anticholinergic agents. Facilitation at the 75-msec delay showed an inverse linear correlation with the bradykinesia intensity (r = -0.7, p < 0.01). The results argue in favor of a reduced excitability of the nucleus reticularis pontis caudalis from which a reticulospinal tract emanates as effector of the audiospinal facilitation. This would represent another example of dysfunction of reticular nuclei in Parkinson's disease. [less ▲]Detailed reference viewed: 12 (7 ULg)
Audiovisual reflexive methodology : How & What can be said, Where?
Stassart, Pierre M ;
Conference (2009)Detailed reference viewed: 17 (0 ULg)
Audit de l’évaluation du personnel : un outil de gestion utile pour les organisations et les institutions ?
De Zanet, Fabrice ; ; Dujardin, Jean-Marie
in Gestion 2000 (2010), 4Detailed reference viewed: 121 (30 ULg)
Audit de la Santé au Travail au Grand Duché du Luxembourg
Mairiaux, Philippe ; Levêque, Audrey ; Pichault, François
Report (2012)Detailed reference viewed: 37 (2 ULg)
L'audit en médecine générale : outils de dépistage et d'intervention
Filée, Dominique ; Gosset, Christiane ; et al
Conference (2002)Detailed reference viewed: 15 (3 ULg)
L'audit social. Evaluez les risques sociaux de votre entreprise !
; Maréchal, Benoît
Conference (2008, December 01)
This seminar introduce to the practice of the social audit with regard to compagnies. On basis of a list of social risks with regard to labour law and social security law, the Authors illustrated how ... [more ▼]
This seminar introduce to the practice of the social audit with regard to compagnies. On basis of a list of social risks with regard to labour law and social security law, the Authors illustrated how these risks could be examined and evaluated in the case of a social audit of the company. [less ▲]Detailed reference viewed: 120 (4 ULg)
Audition au Parlement Wallon en tant qu'expert- évaluation du code de démocratie locale
Report (2007)Detailed reference viewed: 7 (0 ULg)
Auditory evoked potentials and multiple personality measures in migraine and post-traumatic headaches.
; ; et al
in Pain (1999), 79(2-3), 235-42
Migraine sufferers have abnormal cerebral information processing and personality disorders, post-traumatic headache sufferers also have some personality changes. We therefore, studied intensity dependence ... [more ▼]
Migraine sufferers have abnormal cerebral information processing and personality disorders, post-traumatic headache sufferers also have some personality changes. We therefore, studied intensity dependence of auditory evoked potentials, Plutchik-van Praag's depression inventory, Zuckerman's sensation seeking scales and Zuckerman-Kuhlman's personality questionnaire in patients suffering from migraine without aura (n = 26) and chronic post-traumatic headaches (n = 26) as well as in healthy volunteers (n = 30). The migraine group showed significantly increased neuroticism-anxiety than controls, increased intensity dependence of N1-P2, and decreased thrill and adventure score compared with the controls and post-traumatic headaches. The post-traumatic headache had significantly increased depression compared with the controls, and increased disinhibition compared with the controls and migraines. This study demonstrates that the two headache types have different neurophysiological and personality traits. The pronounced intensity dependence of N1-P2 suggests a cortical potentiation response, together with a decreased thrill and adventure seeking, favor a lower serotonergic innervation in migraine. While the elevated disinhibition and depression, as consequences, may be linked with the wide cortical neuronal/axonal degeneration in post-traumatic headache. [less ▲]Detailed reference viewed: 18 (2 ULg)
Auditory evoked potentials in the assessment of central nervous system effects of antimigraine drugs.
; ; et al
in Cephalalgia : An International Journal of Headache (1999), 19(10), 880-5
Because the "intensity dependence" of cortical auditory evoked potentials (IDAP) is under serotonergic control, it can be used to assess central antimigraine effects of 5HT1B/1D agonists. We measured IDAP ... [more ▼]
Because the "intensity dependence" of cortical auditory evoked potentials (IDAP) is under serotonergic control, it can be used to assess central antimigraine effects of 5HT1B/1D agonists. We measured IDAP before and 2 h after naratriptan (5 mg, n = 19) and zolmitriptan (5 mg, n = 19) in healthy volunteers. IDAP was expressed as the amplitude-stimulus intensity function ("ASF slope"). Naratriptan tended to increase ASF slope (mean difference 0.23 +/- 0.62 microV/10 dB, p = 0.06) while zolmitriptan (0.08 +/- 0.95 microV/10 dB, p = 0.35) did not. We assessed the suitability of IDAP for measuring central antimigraine drug effects using repeatability data (see companion paper). We calculated the trade-off between the size of the expected drug effects (ASF slope difference) and the necessary sample size. Because of poor repeatability 36 to 80 subjects are required to detect ASF slope changes in the 0.25-0.5 microV/10 dB range. These data can be used to design trials using IDAP. [less ▲]Detailed reference viewed: 15 (0 ULg)
Auditory forebrain activation in the female canary is modulated by male song quality.
Barker, Jennifer ; ; et al
Poster (2010, November 17)
One of the chief functions of birdsong is to attract and stimulate females. In canaries (Serinus canaria), speciﬁc phrases (“A” phrases) sung by males have been identiﬁed as especially attractive for ... [more ▼]
One of the chief functions of birdsong is to attract and stimulate females. In canaries (Serinus canaria), speciﬁc phrases (“A” phrases) sung by males have been identiﬁed as especially attractive for females. These phrases unite a number of characteristics that are particularly difﬁcult to combine, including large frequency bandwidth, high repetition rate and multiple-note syllables. Females exposed to “A” phrases produce more copulation displays and deposit more testosterone into their eggs. However, the neuroendocrine pathway underlying the translation of song audition to changes in testosterone deposition in yolks is not understood. Increased expression of several immediate early genes including c-fos and zenk (also called egr-1 in mammals) in other songbird species has been observed in the auditory forebrain of females hearing attractive song, and such differential activation may represent a ﬁrst step in signal processing linking auditory input to egg testosterone deposition. Female canaries in breeding condition were exposed to 60 minutes of “sexy” song with a preponderance of “A” phrases, “non-sexy” song lacking “A” phrases, or white noise. Thirty minutes after the end of song playback, brains were collected, ﬁxed in acrolein and sectioned and stained by immunohistochemistry for quantiﬁcation of the Fos protein, an indicator of neuronal activity, in several regions involved in audition and auditory processing. The endocrine condition of each female was determined by measuring ovarian and oviduct weight at the time of autopsy. In the caudomedial mesopallium (CMM), Fos expression was higher in females that had heard sexy song than those that heard non-sexy song or white noise. Expression of Fos in the caudomedial nidopallium (NCM), the nucleus spiriformis medialis (SPM), the nucleus ovoidalis (OV), and the song nucleus HVC was unaffected by song quality. Thus differential auditory processing in the CMM may be an initial stage in the assessment by a female of song information to differential testosterone deposition in the egg. [less ▲]Detailed reference viewed: 17 (2 ULg)
Auditory hallucinations in schizophrenia and non-schizophrenia populations: A review and integrated model of cognitive mechanisms
; ; et al
in Schizophrenia Bulletin (2012), 38Detailed reference viewed: 25 (0 ULg)
Auditory P300 and the altered consciousness: detecting altered states of consciousness using the P300 speller
; ; Chatelle, Camille et al
in Proceedings of TOBI Workshop 2010: Integrating Brain-Computer Interfaces with Conventional Assistive Technology (2010)Detailed reference viewed: 7 (1 ULg)
Auditory processing in severely brain injured patients: differences between the minimally conscious state and the persistent vegetative state.
Boly, Mélanie ; FAYMONVILLE, Marie-Elisabeth ; Peigneux, Philippe et al
in Archives of Neurology (2004), 61(2), 233-8
BACKGROUND: The minimally conscious state (MCS) is a recently defined clinical condition; it differs from the persistent vegetative state (PVS) by the presence of inconsistent, but clearly discernible ... [more ▼]
BACKGROUND: The minimally conscious state (MCS) is a recently defined clinical condition; it differs from the persistent vegetative state (PVS) by the presence of inconsistent, but clearly discernible, behavioral evidence of consciousness. OBJECTIVE: To study auditory processing among patients who are in an MCS, patients who are in a PVS, and healthy control subjects. METHODS: By means of (15)O-radiolabeled water-positron emission tomography, we measured changes in regional cerebral blood flow induced by auditory click stimuli in 5 patients in an MCS, 15 patients in a PVS, and 18 healthy controls. RESULTS: In both patients in an MCS and the healthy controls, auditory stimulation activated bilateral superior temporal gyri (Brodmann areas 41, 42, and 22). In patients in a PVS, the activation was restricted to Brodmann areas 41 and 42 bilaterally. We also showed that, compared with patients in a PVS, patients in an MCS demonstrated a stronger functional connectivity between the secondary auditory cortex and temporal and prefrontal association cortices. CONCLUSIONS: Although assumptions about the level of consciousness in severely brain injured patients are difficult to make, our findings suggest that the cerebral activity observed in patients in an MCS is more likely to lead to higher-order integrative processes, thought to be necessary for the gain of conscious auditory perception. [less ▲]Detailed reference viewed: 10 (2 ULg)
Auditory processing in the vegetative state.
Laureys, Steven ; Faymonville, Marie ; Degueldre, Christian et al
in Brain : A Journal of Neurology (2000), 123 ( Pt 8)
H(2)(15)O-PET was used to investigate changes in regional cerebral blood flow in response to auditory stimulation in patients in the vegetative state. Five patients in a vegetative state of hypoxic origin ... [more ▼]
H(2)(15)O-PET was used to investigate changes in regional cerebral blood flow in response to auditory stimulation in patients in the vegetative state. Five patients in a vegetative state of hypoxic origin were compared with 18 age-matched controls. In addition, the cerebral metabolism of these patients and 53 age-matched controls was studied using [(18)F]fluorodeoxyglucose. In control subjects, auditory click stimuli activated bilateral auditory cortices [Brodmann areas (BA) 41 and 42] and the contralateral auditory association cortices (BA 22). In the patients, although resting metabolism was decreased to 61% of normal values, bilateral auditory areas 41 and 42 showed activation as seen in the controls, but the temporoparietal junction cortex (BA 22) failed to be activated. Moreover, the auditory association cortex was functionally disconnected from the posterior parietal association area (BA 40), the anterior cingulate cortex (BA 24) and the hippocampus, as revealed by psychophysiological interaction analysis. Thus, despite altered resting metabolism, the auditory primary cortices were still activated during external stimulation, whereas hierarchically higher-order multi- modal association areas were not. Such a cascade of functional disconnections along the auditory cortical pathways, from the primary auditory areas to multimodal and limbic areas, suggests that the residual cortical processing observed in the vegetative state cannot lead to the integrative processes that are thought to be necessary for the attainment of the normal level of awareness. [less ▲]Detailed reference viewed: 31 (3 ULg)
Auditory resting-state network connectivity in tinnitus: a functional MRI study.
; Lefèbvre, Philippe ; et al
in PLoS ONE (2012), 7(5), 36222
The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test ... [more ▼]
The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test if functional MRI "resting-state" connectivity patterns in auditory network differ between tinnitus patients and normal controls. Thirteen chronic tinnitus subjects and fifteen age-matched healthy controls were studied on a 3 tesla MRI. Connectivity was investigated using independent component analysis and an automated component selection approach taking into account the spatial and temporal properties of each component. Connectivity in extra-auditory regions such as brainstem, basal ganglia/NAc, cerebellum, parahippocampal, right prefrontal, parietal, and sensorimotor areas was found to be increased in tinnitus subjects. The right primary auditory cortex, left prefrontal, left fusiform gyrus, and bilateral occipital regions showed a decreased connectivity in tinnitus. These results show that there is a modification of cortical and subcortical functional connectivity in tinnitus encompassing attentional, mnemonic, and emotional networks. Our data corroborate the hypothesized implication of non-auditory regions in tinnitus physiopathology and suggest that various regions of the brain seem involved in the persistent awareness of the phenomenon as well as in the development of the associated distress leading to disabling chronic tinnitus. [less ▲]Detailed reference viewed: 3 (0 ULg)