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See detailImproved coloration contrast and electrochromic efficiency of tungsten oxide films thanks to a surfactant-assisted ultrasonic spray pyrolysis process
Denayer, Jessica ULg; Aubry, Philippe; Bister, Geoffroy et al

in Solar Energy Materials & Solar Cells (2014), 130

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See detailImproved computer-assisted analysis of the global lymphatic network in human cervical tissues.
Balsat, Cédric ULg; Signolle, Nicolas; GOFFIN, Frédéric ULg et al

in Modern Pathology : An Official Journal of the United States & Canadian Academy of Pathology, Inc (2014), 27(6), 887-98

Lymphatic dissemination is a key event in cervical cancer progression and related tumor lymphatic markers are viewed as promising prognostic factor of nodal extension. However, validating such parameters ... [more ▼]

Lymphatic dissemination is a key event in cervical cancer progression and related tumor lymphatic markers are viewed as promising prognostic factor of nodal extension. However, validating such parameters requires an objective characterization of the lymphatic vasculature. Here, we performed a global analysis of the lymphatic network using a new computerized method applied on whole uterine cervical digital images. Sixty-eight cases of cervical neoplasia (12 CIN3, 10 FIGO stage 1A and 46 stage IB1) and 10 cases of normal cervical tissue were reacted with antibodies raised against D2-40, D2-40/p16 and D2-40/Ki67. Immunostained structures were automatically detected on whole slides. The lymphatic vessel density (D2-40), proliferating lymphatic vessel density (D2-40/ki67) and spatial lymphatic distribution in respect to the adjacent epithelium were assessed from normal cervix to early cervical cancer and correlated with lymphovascular space invasion and lymph node status. Prominent lymphatic vessel density and proliferating lymphatic vessel density are detected under the transformation zone of benign cervix and no further increase is noted during cancer progression. Notably, a shift of lymphatic vessel distribution toward the neoplastic edges is detected. In IB1 cervical cancer, although intra- and peritumoral lymphatic vessel density are neither correlated with lymphovascular space invasion nor with lymph node metastasis, a specific spatial distribution with more lymphatic vessels in the vicinity of tumor edges is predictive of lymphatic dissemination. Herein, we provide a new computerized method suitable for an innovative detailed analysis of the lymphatic network. We show that the transformation zone of the benign cervix acts as a baseline lymphangiogenic niche before the initiation of neoplastic process. During cancer progression, this specific microenvironment is maintained with lymphatic vessels even in closer vicinity to tumor cells.Modern Pathology advance online publication, 6 December 2013; doi:10.1038/modpathol.2013.195. [less ▲]

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See detailAn Improved Constitutive Model for the Numerical Simulation of Semi-Solid Thixoforming
Koeune, Roxane ULg; Ponthot, Jean-Philippe ULg

in Proceedings of ACOMEN’2008, Advanced Computational Methods in Engineering (2008)

In order to model thixoforming processes, previous papers presented a thermo-mechanical one-phase modelling. This first version of constitutive model revealed several limitations: the model could not ... [more ▼]

In order to model thixoforming processes, previous papers presented a thermo-mechanical one-phase modelling. This first version of constitutive model revealed several limitations: the model could not degenerate properly to pure solid or liquid behaviour neither to free solid suspensions. The aim of this paper was to propose solutions to overcome these limitations. [less ▲]

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See detailAn improved constitutive model for the numerical simulation of semi-solid thixoforming
Koeune, Roxane ULg; Ponthot, Jean-Philippe ULg

in Journal of Computational & Applied Mathematics (2010), 234

In order to model thixoforming processes, previous papers presented a thermomechanical one-phase modelling. This first version of the constitutive model revealed several limitations: the model could not ... [more ▼]

In order to model thixoforming processes, previous papers presented a thermomechanical one-phase modelling. This first version of the constitutive model revealed several limitations: the model could not degenerate properly to pure solid or liquid behavior nor to free solid suspensions. The aim of this paper was to propose solutions to overcome these limitations. [less ▲]

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See detailImproved detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide and interleukin-2 stimulation: A Belgian multicentric study.
Put, Natalie; Konings, Peter; Rack, Katrina et al

in Genes, Chromosomes & Cancer (2009), 48(10), 843-53

We performed a multicentric study to assess the impact of two different culture procedures on the detection of chromosomal abnormalities in 217 consecutive unselected cases with chronic lymphocytic ... [more ▼]

We performed a multicentric study to assess the impact of two different culture procedures on the detection of chromosomal abnormalities in 217 consecutive unselected cases with chronic lymphocytic leukemia (CLL) referred for routine analysis either at the time of diagnosis (n = 172) or during disease evolution (n = 45). Parallel cultures of peripheral blood or bone marrow were set up with the addition of either the conventional B-cell mitogen 12-O-tetradecanoyl-phorbol-13-acetate (TPA) or a combination of CpG oligonucleotide (CpG) and interleukin-2 (IL-2). Cytogenetic analyses were performed on both cultures. Clonal abnormalities were identified in 116 cases (53%). In 78 cases (36%), the aberrant clone was detected in both cultures. Among these, the percentages of aberrant metaphases were similar in both conditions in 17 cases, higher in the CpG/IL-2 culture in 43 cases, and higher in the TPA culture in 18 cases. Clonal aberrations were detected in only one culture, either in CpG/IL-2 or TPA in 33 (15%) and 5 (2%) cases, respectively. Taken together, abnormal karyotypes were observed in 51% with CpG/IL-2 and 38% with TPA (P < 0.0001). Application of FISH (n = 201) allowed the detection of abnormalities not visible by conventional cytogenetic analysis in 80 cases: del(13q) (n = 71), del(11q) (n = 5), +12 (n = 2), del(14q) (n = 1), and del(17p) (n = 1). In conclusion, our results confirm that CpG/IL-2 stimulation increases the detection rate of chromosomal abnormalities in CLL compared with TPA and that further improvement can be obtained by FISH. However, neither conventional cytogenetics nor FISH detected all aberrations, demonstrating the complementary nature of these techniques. [less ▲]

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See detailImproved District Heating Network Operation by the Integration of High Temperature Heat Pumps
Sartor, Kevin ULg; Lemort, Vincent ULg; Dewallef, Pierre ULg

in Digital proceedings of the 8th Conference on Sustainable Development of Energy, Water and Environment Systems - SDEWES (2013, September 23)

Biomass Combined Heat and Power (CHP) plants connected to district heating networks are a very good opportunity to increase the share of renewable sources into energy systems. Frequently, important ... [more ▼]

Biomass Combined Heat and Power (CHP) plants connected to district heating networks are a very good opportunity to increase the share of renewable sources into energy systems. Frequently, important consumers are connected to ensure a stable base demand of heat throughout the year but they often have higher requirements in terms of temperature (i.e., steam) which involves high level of temperatures in the district heating network during the whole year and high levels of heat losses in the network. This contribution presents the possibility to decrease the level of temperature at which the district heating network operates and to use high temperature heat pumps connected locally at the consumption point to produce steam when needed. An investigation of the global design and integration through thermodynamic simulation models is realized for the University of Liège district heating network. This study is intended to determine the heat pump coefficient of performance and, therefore, to assess the balance between the savings in terms of heat losses and the additional heat pump electricity consumption. [less ▲]

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See detailImproved Domain Decomposition Method for the Helmholtz Equation
Thierry, Bertrand ULg; Antoine, X.; Boubendir, Y. et al

in Proceedings of the 21th International Conference on Domain Decomposition Methods (DD21) (2012, June)

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See detailImproved Domain Decomposition Method for the Helmholtz Equation"
Geuzaine, Christophe ULg; Antoine, X.; Boubendir, Y. et al

Scientific conference (2012, January 23)

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See detailImproved Domain Decomposition Method for the Wave Equation in Harmonic Regime
Geuzaine, Christophe ULg; Antoine, X.; Boubendir, Y. et al

in Proceedings of the 6th Advanced Computational Electromagnetics workshop (ACE 2012) (2012, March)

Detailed reference viewed: 37 (4 ULg)
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See detailAn improved ELISA technique for the diagnosis of Psoroptes ovis infestations in cattle
Lonneux, J. F.; Mignon, Bernard ULg; Bossaert, K. et al

Poster (2005)

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See detailImproved emulsifying and foaming of whey proteins after enzymic fat hydrolysis
Blecker, Christophe ULg; Paquot, Michel ULg; Lamberti, I. et al

in Journal of Food Science (1997), 62(1), 48-

In an effort to improve emulsifying and foaming of sweet whey and whey protein concentrate, we studied the hydrolysis of the residual fat in these preparations with a sn 1,3 specific lipase. This ... [more ▼]

In an effort to improve emulsifying and foaming of sweet whey and whey protein concentrate, we studied the hydrolysis of the residual fat in these preparations with a sn 1,3 specific lipase. This enzymatic lipolysis would convert almost all triglycerides into mono- and diglycerides which have strong surface-active properties. Therefore, the emulsifying and foaming capacities of such modified whey products should be increased in comparison with native products, as shown by results presented at both neutral pH and those similar to a salad dressing emulsion. It was also demonstrated that emulsions and foams formed with lipase-treated whey preparations were more shelf-stable. [less ▲]

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See detailImproved energy resolution of a cyclotron beam for RBS measurements
Chene, Grégoire ULg; Garnir, Henri-Pierre ULg; Marchal, André ULg et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2008), 266(10), 2110-2112

Detailed reference viewed: 57 (23 ULg)
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See detailImproved Experimental and Theoretical Energy Levels of Neon I
Chang, E. S.; Schoenfeld, W. G.; Biémont, Emile ULg et al

in Physica Scripta (1994), 49

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See detailImproved extraction of valence transversity distributions from inclusive dihadron production
Radici, Marco; Courtoy, Aurore ULg; Bacchetta, Alessandro et al

in Journal of High Energy Physics [=JHEP] (2015), 1505

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See detailImproved Finite Element Solvers for the Helmholtz Equation at High Frequencies
Geuzaine, Christophe ULg

Scientific conference (2012, March 29)

Detailed reference viewed: 34 (2 ULg)
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See detailImproved first order moment method for determination of mass-loss rates
Hutsemekers, Damien ULg; Surdej, Jean ULg

in Bianchi, L.; Gilmozzi, R. (Eds.) Mass outflows from stars and galactic nuclei; Proceedings of the Second Torino Workshop (1988)

The first order moment of P Cygni line profiles has been computed for the case of doublets and subordinate line transitions. This improved method can be used for deriving more accurate mass-loss rates of ... [more ▼]

The first order moment of P Cygni line profiles has been computed for the case of doublets and subordinate line transitions. This improved method can be used for deriving more accurate mass-loss rates of planetary nebula nuclei, broad absorption line quasars, etc. [less ▲]

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See detailImproved Forwarding Architecture and Resource Management for Multi-Core Software Routers
Egi, Norbert; Greenhalgh, Adam; Handley, Mark et al

in NPC 2009 Proceedings (2009, October)

Recent technological advances in commodity server architectures, with multiple multi-core CPUs, integrated memory controllers, high-speed interconnects and enhanced network interface cards, provide ... [more ▼]

Recent technological advances in commodity server architectures, with multiple multi-core CPUs, integrated memory controllers, high-speed interconnects and enhanced network interface cards, provide substantial computational capacity and thus an attractive platform for packet forwarding. However, to exploit this available capacity, we need a suitable software platform that allows effective parallel packet processing and resource management. In this paper, we at first introduce an improved forwarding architecture for software routers that enhances parallelism by exploiting hardware classification and multi-queue support, already available in recent commodity network interface cards. After evaluating the original scheduling algorithm of the widely-used Click modular router, we propose solutions for extending this scheduler for improved fairness, throughput and more precise resource management. To illustrate the potential benefits of our proposal, we implement and evaluate a few key elements of our overall design. [less ▲]

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See detailImproved Four-Color Flow Cytometry Method Using Fluo-3 and Triple Immunofluorescence for Analysis of Intracellular Calcium Ion ([Ca2+]I) Fluxes among Mouse Lymph Node B- and T-Lymphocyte Subsets
Greimers, Roland ULg; Trebak, M.; Moutschen, Michel ULg et al

in Cytometry (1996), 23(3), 205-17

A visible-light, dual-laser, flow cytometric method was developed for the simultaneous analysis of intracellular ionized calcium concentration ([Ca2+]i) and three cell-surface markers (CD4, CD8, and Thy-1 ... [more ▼]

A visible-light, dual-laser, flow cytometric method was developed for the simultaneous analysis of intracellular ionized calcium concentration ([Ca2+]i) and three cell-surface markers (CD4, CD8, and Thy-1.2 antigens) by using the calcium probe fluo-3 and using R-phycoerythrin (PE), peridinin chlorophyll-alpha protein (PerCP), and allophycocyanin (APC) conjugated monoclonal antibodies (MoAbs). This improved method was used in the analysis of [Ca2+]i mobilization upon in vitro stimulation with mitogenic lectins [phytohaemagglutinin (PHA) or concanavalin A (ConA)], anti-CD3 MoAbs, or A23187 calcium ionophore in the heterogeneous lymph node cell populations from healthy C57BL/Ka mice. The present results show that the calcium responses were heterogeneous and dependent on the cellular immunophenotype, not only on lectins or anti-CD3 MoAbs stimulation, but also on the receptor-independent A23187 ionophore stimulation. An in situ fluo-3 calibration method (using A23187 and metabolic poisons in Ca2+ /EGTA buffers with known free calcium concentrations) indicated a resting [Ca2+]i in lymphocytes of 103 +/- 23 nM (mean +/- S.D.) but with significant differences between the [Ca2+]i in B cells and in all of the T-cell subsets (CD4+Thy-1+, CD4+Thy-1-, and CD8+T cells). Both the B cells and the T-cell subsets showed an increase of fluo-3 fluorescence upon in vitro stimulation with ConA or PHA, but the calcium mobilization following lectin stimulation was time delayed in all T-cell subsets. Only the T cells, including the CD4+Thy-1- subset, responded to anti-CD3 MoAbs. The percentage of responding cells upon stimulation with ConA was higher in T cells than in B cells. By contrast, PHA gave a higher response in B cells. After stimulation with different mitogens, [Ca2+]i increased in both CD4+ and CD8+ T-cell subsets. However, the percentage of responding cells was far higher in the CD4+Thy-1+ subset than in the CD4+Thy-1- or the CD8+T-cell subsets. The stimulation with A23187 ionophore induced a higher calcium response in B cells than in T cells. Interestingly, it also induced greater Ca2+ mobilization in CD4+ than in CD8+T cells. These results demonstrate the potential use of fluo-3 simultaneously with three fluorescein (FITC)-compatible fluorochromes. This technique may be useful for investigating the role of the CD4+Thy-1-T cells, a rare subset that is abnormally expanded in a murine acquired immunodeficiency syndrome (murine AIDS). [less ▲]

Detailed reference viewed: 224 (7 ULg)