Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailNaturally occurring BLV- LTR variants show differential binding with transcriptional regulator E2F-4
Rodriguez, Sabrina ULg; Varone, C.; Cánepa, E. et al

in AIDS Research and Human Retroviruses (2007, April 23), 23(4), 657

Naturally occurring BLV- LTR variants show differential binding with transcriptional regulator E2F-4. Sabrina M. Rodríguez1, Cecilia Varone2, Eduardo Cánepa2, Karina Trono1. srodriguez@cnia.inta.gov.ar ... [more ▼]

Naturally occurring BLV- LTR variants show differential binding with transcriptional regulator E2F-4. Sabrina M. Rodríguez1, Cecilia Varone2, Eduardo Cánepa2, Karina Trono1. srodriguez@cnia.inta.gov.ar 1Instituto de Virología. CICVyA. INTA-Castelar. Castelar. Buenos Aires. Argentina 2Catedra de Biología Molecular. Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Buenos Aires. Argentina The proviral Long Terminal Repeats (LTR) of retroviruses constitute a critical element involved in the regulation of viral and cellular gene expression. It is well known for some viruses within the Retroviridae family that minimal changes in this region can influence tropism, virulence and pathogenicity. The aim of this work was to elucidate if there is any association between the binding capacity of the Bovine Leukemia Virus (BLV) LTR region with cellular transcription factors and the pathogenic evolution of natural infection. The complete 5´LTR sequence amplified from mononuclear cells and tumour tissues of 40 naturally infected cattle was analyzed. Sequence analysis revealed the presence of two LTR variants associated with the different BLV pathogenic phenotypes: aleukemic (AL), persistent lymphocitosis (PL) and lymphosarcoma (LS). Analysis by EMSA showed a clearly weaker specific binding pattern when a LS-derived sequence was used as probe. Together with this finding, we also demonstrated by gel shift and supershift assays that the cellular transcription factor E2F-4 specifically interacts with a putative E2F binding motif within the U5 region of BLV 5`LTR unveiled by “in sillico” analysis. The results of this work demonstrates for the first time the presence of differential binding capacity of BLV natural derived variants to cellular nuclear proteins, together with physical characterization of an E2F-4 binding site in the U5 region of BLV-LTR that shows preferential binding to AL/PL derived sequences. These findings can contribute to the knowledge of LTR-driven regulation of viral and cellular gene expression. [less ▲]

Detailed reference viewed: 7 (0 ULg)
Peer Reviewed
See detailNature and distribution of pulmonary vascular resistance during endotoxin insult in intact dogs
D'Orio, Vincenzo ULg; FATEMI, M; MARNETTE, JM et al

in American Review of Respiratory Disease (1992), 4

Detailed reference viewed: 12 (1 ULg)
Peer Reviewed
See detailThe nature and evolution of working memory deficits in multiple sclerosis
DELRUE, Gaël ULg; Caps, Emilie; Gryglewicz, Céline et al

Poster (2007, October 12)

Detailed reference viewed: 13 (1 ULg)
Full Text
See detailLa nature de l'acte juridique attesté par l'O. Mich. III 1098
Straus, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1997), LXXII(143), 128-129

O. Mich. III 1098 attests the delivery of a slave as a surety of a loan.

Detailed reference viewed: 25 (5 ULg)
See detail"Nature des fonctions en grammaire"; "Fonctions des natures en grammaire"
Defays, Jean-Marc ULg

Scientific conference (2011, February 22)

Detailed reference viewed: 11 (1 ULg)
Peer Reviewed
See detailNature des traitements morphologiques chez les dyslexiques : une étude en amorçage masqué
Quemart, Pauline ULg; Casalis, Séverine

Conference (2010, September)

Detailed reference viewed: 25 (0 ULg)
See detailNature du phosphore dans deux échantillons de gypse Imacid
Bastin, David ULg

Report (2000)

Detailed reference viewed: 3 (0 ULg)
Peer Reviewed
See detailNature et qualités de spatiocartes
Donnay, Jean-Paul ULg

in Bulletin de la Société Géographique de Liège (2000), 38

Detailed reference viewed: 10 (0 ULg)
Full Text
See detailNature et sanction(s) de l'article 701 du Code judiciaire
Boularbah, Hakim ULg

in Journal des Tribunaux (2009)

Detailed reference viewed: 21 (1 ULg)
See detailNature et tendances de la cartographie assistée par ordinateur
Donnay, Jean-Paul ULg

in Nouvelles tendances de la géographie en Belgique (1994)

Detailed reference viewed: 5 (0 ULg)
Full Text
See detailNature humaine et personne singulière : l'éternel débat de la psychologie
Richelle, Marc ULg

in Psychologica (2004)

The author continues here an electronic dialogue with Manuel Abreu, initiated on the occasion of two scientific events (Centenary of the French Psychological Society [2001] and an Homage to Paul Fraisse ... [more ▼]

The author continues here an electronic dialogue with Manuel Abreu, initiated on the occasion of two scientific events (Centenary of the French Psychological Society [2001] and an Homage to Paul Fraisse in the frame of a meeting of the Association of French Language Scientific Psychology [2002]) and a parallel drawn between the careers of Paul Fraisse and Joseph Nuttin. The author discusses various lines of rupture that keep impeding any unification in psychology, any conciliation between basic research and applications, between the search for general laws and the individual approach to the subject, between cognitivist reductionism and concern with pluridimensional integration of the person. Are we to put up with such incompatibilities , as derived from two distinct epistemologies, or look beyond for complementarities? The later seems to have been Manuel Abreu's choice in his research and his teaching. The debat is still open. [less ▲]

Detailed reference viewed: 66 (0 ULg)
See detailLa nature juridique du quota d'émission de gaz à effet de serre
Pâques, Michel ULg

in MAES, F. (Ed.) L'échange des droits de pollution comme instrument de gestion du climat (2005)

Detailed reference viewed: 68 (12 ULg)
Peer Reviewed
See detailLa nature juridique et les conditions de l'assurance indélicatesse
Paris, Catherine ULg

in Recueil de jurisprudence - Responsabilité - Assurances - Accidents du travail - Vol I - Jurisprudence 2011 (2013)

Detailed reference viewed: 36 (2 ULg)
See detailNature morte et poésie
Delville, Michel ULg

Scientific conference (2002, April 22)

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailThe nature of the high Galactic latitude O-star HD 93521: new results from X-ray and optical spectroscopy
Rauw, Grégor ULg; Morel, Thierry ULg; Palate, Matthieu ULg

in Astronomy and Astrophysics (2012), 546

Context. Owing to its unusual location and its isolation, the nature of the high Galactic latitude O9.5 Vp object HD 93521 is still uncertain. <BR /> Aims: We have collected X-ray and optical observations ... [more ▼]

Context. Owing to its unusual location and its isolation, the nature of the high Galactic latitude O9.5 Vp object HD 93521 is still uncertain. <BR /> Aims: We have collected X-ray and optical observations to characterize the star and its surroundings. <BR /> Methods: X-ray images and spectra are analysed to search for traces of a recent star formation event around HD 93521 and to search for the signature of a possible compact companion. Optical echelle spectra are analysed with plane-parallel model atmosphere codes, assuming either a spherical star or a gravity darkened rotationally flattened star, to infer the effective temperature and surface gravity, and to derive the He, C, N and O abundances of HD 93521. <BR /> Results: The X-ray images reveal no traces of a population of young low-mass stars coeval with HD 93521. The X-ray spectrum of HD 93521 is consistent with a normal late O-type star although with subsolar metallicity. No trace of a compact companion is found in the X-ray data. In the optical spectrum, He and N are found to be overabundant, in line with the effect of rotational mixing in this very fast rotator, whilst C and O are subsolar. A critical comparison with the properties of subdwarf OB stars, indicates that, despite some apparent similarities, HD 93521 does not belong to this category. <BR /> Conclusions: Despite some ambiguities on the runaway status of the star, the most likely explanation is that HD 93521 is a Population I massive O-type star that was ejected from the Galactic plane either through dynamical interactions or a result of a supernova event in a binary system. Based on observations collected at the Observatoire de Haute Provence (France) and with XMM-Newton, an ESA science mission with instruments and contributions directly funded by ESA member states and the USA (NASA).Hα images are only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via <A href="http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/546/A77">http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/546/A77</A> [less ▲]

Detailed reference viewed: 29 (3 ULg)
Peer Reviewed
See detailNature of the late potentials and F-ratio values in dogs
Poncelet, Luc; Balligand, Marc ULg

in Research in Veterinary Science (1991)

Detailed reference viewed: 7 (0 ULg)