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See detailA Meta Model to Optimal Design the VSI T2 Chart
Faraz, Alireza ULg; Heuchenne, Cédric ULg; Saniga, E.

Report (2010)

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See detailA Meta Model to Optimally Design the VSI T2 Control Chart
Faraz, Alireza ULg; Seif, A.

in international Journal of Applied Operational Research (2012), 1(3), 53-69

Recent studies have shown that the variable sampling interval (VSI) scheme helps practitioners to detect process shifts more quickly than the classical scheme (FRS). In this paper, the economically and ... [more ▼]

Recent studies have shown that the variable sampling interval (VSI) scheme helps practitioners to detect process shifts more quickly than the classical scheme (FRS). In this paper, the economically and statistically optimal design of the VSI T2 control chart for monitoring the process mean vector is investigated. The cost model proposed by Lorenzen and Vance [1] based on the Markov chain approach is modified as the objective function which is intended to be minimized through a genetic algorithm (GA) approach. Then, the effects of the costs and operating parameters on the optimal design (OD) of the chart parameters; and resulting operating loss through a fractional factorial design is systematically studied and finally, based on the ANOVA results, a Meta model to facilitate implementation in industry is proposed to determine the OD of the VSI T2 control chart parameters from the process and cost parameters. [less ▲]

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See detailMéta-analyse des études de qualite de vie internationales.
Louis, Renaud ULg

in Revue des Maladies Respiratoires (2005), 22(2 Pt 3), 446-8

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See detailLa méta-analyse des recherches expérimentales en éducation
Leclercq, Dieudonné ULg

in Revue de la Direction Générale de l’Organisation des Etudes (1986), mai

Le présent document est organisé autour d'une synthèse de divers travaux menés par J. Kulik et ses collègues du C.R.L.T. dont le LOGO oppose la progression irrégulière de l'individu (ligne brisée) à la ... [more ▼]

Le présent document est organisé autour d'une synthèse de divers travaux menés par J. Kulik et ses collègues du C.R.L.T. dont le LOGO oppose la progression irrégulière de l'individu (ligne brisée) à la courbe lisse de la progression collective (statistique) vers la maîtrise. [less ▲]

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See detailMeta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Anderson, Carl A; Boucher, Gabrielle; Lees, Charlie W et al

in Nature Genetics (2011), 43(3), 246-52

Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-wide association ... [more ▼]

Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-wide association study datasets, comprising 6,687 cases and 19,718 controls, and followed up the top association signals in 9,628 cases and 12,917 controls. We identified 29 additional risk loci (P < 5 x 10(-8)), increasing the number of ulcerative colitis-associated loci to 47. After annotating associated regions using GRAIL, expression quantitative trait loci data and correlations with non-synonymous SNPs, we identified many candidate genes that provide potentially important insights into disease pathogenesis, including IL1R2, IL8RA-IL8RB, IL7R, IL12B, DAP, PRDM1, JAK2, IRF5, GNA12 and LSP1. The total number of confirmed inflammatory bowel disease risk loci is now 99, including a minimum of 28 shared association signals between Crohn's disease and ulcerative colitis. [less ▲]

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See detailMeta-Analysis in Transcriptional Network Inference
Meyer, Patrick ULg; Haibe-Kains, Benjamin; Bontempi, Gianluca

in Recomb Satellite 09 (2009)

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See detailMeta-analysis of the effects of inhaled corticosteroids on bone in asthmatic and COPD patients
Richy, Florent; Bousquet, Jean; Devogelaer, Jean-Pierre et al

in Arthritis and Rheumatism (2002, September), 46(number 9 (suppl.)), 464

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See detailMeta-Cognitive Mystery Tales
Dechêne, Antoine ULg

Conference (2014, April)

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See detailMeta-learning of Exploration/Exploitation Strategies: The Multi-Armed Bandit Case
Maes, Francis; Wehenkel, Louis ULg; Ernst, Damien ULg

in Filipe, Joaquim; Fred, Ana (Eds.) Agents and Artificial Intelligence: 4th International Conference, ICAART 2012, Vilamoura, Portugal, February 6-8, 2012. Revised Selected Papers (2013)

The exploration/exploitation (E/E) dilemma arises naturally in many subfields of Science. Multi-armed bandit problems formalize this dilemma in its canonical form. Most current research in this field ... [more ▼]

The exploration/exploitation (E/E) dilemma arises naturally in many subfields of Science. Multi-armed bandit problems formalize this dilemma in its canonical form. Most current research in this field focuses on generic solutions that can be applied to a wide range of problems. However, in practice, it is often the case that a form of prior information is available about the specific class of target problems. Prior knowledge is rarely used in current solutions due to the lack of a systematic approach to incorporate it into the E/E strategy. To address a specific class of E/E problems, we propose to proceed in three steps: (i) model prior knowledge in the form of a probability distribution over the target class of E/E problems; (ii) choose a large hypothesis space of candidate E/E strategies; and (iii), solve an optimization problem to find a candidate E/E strategy of maximal average performance over a sample of problems drawn from the prior distribution. We illustrate this meta-learning approach with two different hypothesis spaces: one where E/E strategies are numerically parameterized and another where E/E strategies are represented as small symbolic formulas. We propose appropriate optimization algorithms for both cases. Our experiments, with two-armed “Bernoulli” bandit problems and various playing budgets, show that the metalearnt E/E strategies outperform generic strategies of the literature (UCB1, UCB1-T UNED, UCB-V, KL-UCB and epsilon-GREEDY); they also evaluate the robustness of the learnt E/E strategies, by tests carried out on arms whose rewards follow a truncated Gaussian distribution. [less ▲]

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See detailMetabolic acidosis during the first 2 weeks of life in VLBW infants receiving high protein intakes
SENTERRE, Thibault ULg; Rigo, J

in Intensive Care Medicine (2011), 37(S2), 397

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See detailMetabolic activity in external and internal awareness networks in severely brain-damaged patients.
Thibaut, Aurore ULg; Bruno, Marie-Aurélie ULg; Chatelle, Camille ULg et al

in Journal of Rehabilitation Medicine (2012), 44(6), 487-94

OBJECTIVE: An extrinsic cerebral network (encompassing lateral frontoparietal cortices) related to external/sensory awareness and an intrinsic midline network related to internal/self-awareness have been ... [more ▼]

OBJECTIVE: An extrinsic cerebral network (encompassing lateral frontoparietal cortices) related to external/sensory awareness and an intrinsic midline network related to internal/self-awareness have been identified recently. This study measured brain metabolism in both networks in patients with severe brain damage. DESIGN: Prospective [18F]-fluorodeoxyglucose-positron emission tomography and Coma Recovery Scale-Revised assessments in a university hospital setting. SUBJECTS: Healthy volunteers and patients in vegetative state/unresponsive wakefulness syndrome (VS/UWS), minimally conscious state (MCS), emergence from MCS (EMCS), and locked-in syndrome (LIS). RESULTS: A total of 70 patients were included in the study: 24 VS/UWS, 28 MCS, 10 EMCS, 8 LIS and 39 age-matched controls. VS/UWS showed metabolic dysfunction in extrinsic and intrinsic networks and thalami. MCS showed dysfunction mostly in intrinsic network and thalami. EMCS showed impairment in posterior cingulate/retrosplenial cortices. LIS showed dysfunction only in infratentorial regions. Coma Recovery Scale-Revised total scores correlated with metabolic activity in both extrinsic and part of the intrinsic network and thalami. CONCLUSION: Progressive recovery of extrinsic and intrinsic awareness network activity was observed in severely brain-damaged patients, ranging from VS/UWS, MCS, EMCS to LIS. The predominance of intrinsic network impairment in MCS could reflect altered internal/self-awareness in these patients, which is difficult to quantify at the bedside. [less ▲]

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See detailMetabolic adaptation to prolonged exercise in severely obese subjects.
Scheen, André ULg; Pirnay, Freddy ULg; Luyckx, A. S. et al

in International Journal of Obesity & Related Metabolic Disorders (1983), 7(3), 221-9

In investigating the metabolic adaptation to prolonged exercise in markedly obese subjects, we compared blood glucose, plasma lactate, free fatty acids, insulin and glucagon concentrations during 3 h of ... [more ▼]

In investigating the metabolic adaptation to prolonged exercise in markedly obese subjects, we compared blood glucose, plasma lactate, free fatty acids, insulin and glucagon concentrations during 3 h of treadmill exercise in nine severely obese male patients (OB) (weight excess 84 +/- 7 per cent of their ideal body weight) and in nine healthy controls (C). Speed and slope of treadmill were selected to give a similar oxygen consumption in both groups (OB: 1.61 +/- 0.08 1/min; C: 1.72 +/- 0.07 1/min). Under these conditions, heart rate was similar in both groups, whereas ventilation was significantly lower in overweight subjects. In obese patients, plasma free fatty acid (FFA) levels were higher in the basal state (OB: 740 +/- 43 mumol/l; C: 602 +/- 40 mumol/l, 2 P less than 0.05) but showed a lower increase during the exercise period (OB: + 576 +/- 135 mumol/l; C: + 1071 +/- 100 mumol/l, 2 P less than 0.02). This impaired FFA mobilization was related to significantly higher insulin (IRI) levels throughout the exercise period as shown by the regression line of exercise-induced FFA increase (y, mumol/l) vs mean plasma IRI during exercise (x, microU/ml): y = 1238 - 60 x, r = -0.709, 2 P less than 0.001. Lack of glucagon increase could also contribute to the lower rise of FFA in obese subjects. A correspondingly increased contribution of carbohydrates to the energy supply is suggested by a significant decline in blood glucose and higher lactate plasma concentrations during the second half of the exercise period in overweight patients. These abnormalities could represent a metabolic limitation for performing prolonged exercise in markedly obese patients. [less ▲]

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