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See detailImprovement of Autobiographical Memory in Schizophrenia Patients Following a Cognitive Intervention: A Preliminary Study.
Blairy, Sylvie ULg; Neumann, Aurore; Nutthals, Frédérique et al

in Psychopathology (2008), 41

Background: Schizophrenia is associated with a reduction in accessing specific autobiographical information. This is consistent with the abnormal development of the personal identity characterizing this ... [more ▼]

Background: Schizophrenia is associated with a reduction in accessing specific autobiographical information. This is consistent with the abnormal development of the personal identity characterizing this mental disorder. The present study evaluates the effect of a cognitive intervention on autobiographical memory and on the capacity to project oneself in the future in people suffering from schizophrenia. Sampling and Method: The intervention consisted of group sessions during which participants were trained to recollect specific events reported in their diary. Further, exercises to stimulate their thoughts on their personal identity were proposed. An AM test was administrated before and after the intervention, as well as at three months follow-up. Further, neuropsychological and affective assessments were conducted before and after treatments. Patients’ performances were compared to those from the control group Results: The capacities to generate specific events are improved by the cognitive intervention, and that the benefits are preserved 3 months later. However, no neuropsychological or affective benefit was found. Conclusion: Despite positive results on specific memory, the significant benefits have to be extended to other clinical variables such as symptom reduction, neuropsychological and social functioning. Nevertheless, the results revealed that CRT on AM could be a useful additional intervention for schizophrenia patients. [less ▲]

Detailed reference viewed: 119 (13 ULg)
See detailImprovement of Buildings' Structural Quality by New Technologies - Outcome of the Cooperative Activities within COST C12
Schaur, C.; Mazzollani, F.; Huber, G. et al

Book published by A.A. Balkema Publishers (2005)

Detailed reference viewed: 21 (4 ULg)
See detailImprovement of Buildings'Structural Quality by New Technologies - Proceedings of the Final COST C12 Conference
Schaur, Christian; Mazzolani, Federico; Huber, Gerald et al

Book published by A.A. Balkema Publishers (2005)

Detailed reference viewed: 48 (5 ULg)
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See detailImprovement of cellulose anaerobic digestion
Kinet, Romain ULg

Scientific conference (2014, December 11)

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See detailImprovement of data quality for Diffusion Kurtosis Imaging and application to clinical neurological research
André, Elodie ULg

Doctoral thesis (2014)

Understanding human brain function and dysfunction is one of the major challenges of our century. One of the most popular methods to achieve this goal is in vivo magnetic resonance imaging. In particular ... [more ▼]

Understanding human brain function and dysfunction is one of the major challenges of our century. One of the most popular methods to achieve this goal is in vivo magnetic resonance imaging. In particular, diffusion-weighted (DW) imaging has become a standard tool to non-invasively study white matter structure in vivo. The main contributions of this work can be divided in two parts. The first part deals with the development of pre-processing methods to improve image quality and the accuracy of diffusion tensor and diffusion kurtosis-derived parameters. First, we describe and evaluate a novel method to correct data misalignment due to subject motion. Using an iterative model-based approach, individual diffusion images are realigned to their own theoretical pair, rather than to the unweighted image. A recently developed advanced measure of tensor distance was used as a stopping criterion. The accuracy of the method is tested via a simulated diffusion tensor imaging data set. We have shown here that our procedure is a reliable and efficient way to correct subject motion during DW acquisitions, and that with a proper acquisition setup, it performs better than standard coregistration procedures. Next, we studied the influence of noise in diffusion kurtosis imaging. Two noise correction approaches are proposed and applied to a pool of 25 subjects to evaluate inter-subject variability and the impact of noise correction. Additionally, data were acquired on a single subject with different head positions within the coil and different acquisition scheme to evaluate the impact of noise correction on within-subject variability. Results show a strong impact of noise correction on the estimated mean kurtosis, while the estimation of fractional anisotropy and mean diffusivity were less affected. Both within- and between-subject signal-to-noise (SNR) related variability of the mean kurtosis estimate is considerably reduced after correction for the noise bias, leading to more accurate and reproducible measures. In this work, we have proposed a straightforward method that improves the accuracy of diffusion kurtosis metrics. Diffusion kurtosis imaging acquisitions at higher spatial resolution are made possible, which increases the chances to make valuable inferences in group analysis.The second part of this thesis deals with a clinical application of these methods. A large group of patients with early-stage Parkinson’s disease was investigated with diffusion kurtosis imaging and compared with a group of age- and sex-matched healthy volunteers using voxel-based analysis. Kurtosis metrics show more sensitivity to white matter changes than standard diffusion metrics. Significant differences were found in posterior cerebral areas as well as subcortical regions like the putamen, and are therefore promising results. [less ▲]

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See detailImprovement of defect detection in shearography by using Principal Component Analysis
Vandenrijt, Jean-François ULg; Lièvre, Nicolas; Georges, Marc ULg

in Proceedings of Conference on Interferometry XVII: Techniques and Analysis (2014, August)

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See detailImprovement Of Enzymatic-Synthesis Yields Of Flavor Acetates - The Example Of The Isoamyl Acetate
Razafindralambo, Hary ULg; Blecker, Christophe ULg; Lognay, Georges ULg et al

in Biotechnology Letters (1994), 16(3), 247-250

Isoamyl acetate synthesis was chosen as a model to improve flavour acetate yields by optimising the enzymatic reaction. Alcohol:acid molar ratio, temperature, water content and amount of enzyme effects ... [more ▼]

Isoamyl acetate synthesis was chosen as a model to improve flavour acetate yields by optimising the enzymatic reaction. Alcohol:acid molar ratio, temperature, water content and amount of enzyme effects were analyzed. The optimum values were respectively 4, 45 degrees C, 0,1% (w/v) and 0,5 g. In these conditions, the synthesis yield reached 80% after 24 h of reaction and was found 15 times greater than those already reported in the literature. [less ▲]

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See detailImprovement of fed batch mass culture for g linolenic biosynthesis by Tetrahymena rostrata (Protozoa).
Gosselin, Y.; Lognay, Georges ULg; Thonart, Philippe ULg

in Biotechnology Letters (1989), 11(6), 423-426

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See detailImprovement Of Fed Batch Mass-Culture For Gamma-Linolenic Biosynthesis By Tetrahymena-Rostrata (Protozoa)
Gosselin, Y.; Lognay, Georges ULg; Thonart, Philippe ULg

in Biotechnology Letters (1989), 11(6), 423-426

Despite' the general high sensitivity of protozoa to shearing effects, Tetrahymena rostrata was cultivated using a controlled fed batch fermentor; the feeding medium contained 15 % skimmed milk. With an ... [more ▼]

Despite' the general high sensitivity of protozoa to shearing effects, Tetrahymena rostrata was cultivated using a controlled fed batch fermentor; the feeding medium contained 15 % skimmed milk. With an unchanged growth rate, final cell concentration (14.105 cell/ml) was 4 times higher than in simple batch culture. gamma-Linolenic acid (16 % of the total fatty acids) reached 0.5 gr/l medium. [less ▲]

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See detailImprovement of fermentative biohydrogen production by Clostridium butyricum CWBI1009 in sequenced-batch, horizontal fixed bed and biodisc-like anaerobic reactors with biomass retention
Hiligsmann, Serge ULg; Beckers, Laurent; Masset, Julien et al

in International Journal of Hydrogen Energy (2014), 39

A horizontal tubular fixed bed bioreactor (HFBR) and an anaerobic biodisc-like reactor (AnBDR) were designed to both fix Clostridium biomass and enable rapid transfer of the hydrogen produced to gas phase ... [more ▼]

A horizontal tubular fixed bed bioreactor (HFBR) and an anaerobic biodisc-like reactor (AnBDR) were designed to both fix Clostridium biomass and enable rapid transfer of the hydrogen produced to gas phase in order to decrease the strong effect of H2 partial pressure and H2 supersaturation on the performances of Clostridium strains. The highest H2 production rate (703 mL H2/L.h) and yield (302 mL/g glucose consumed i.e. 2.4 mol/mol) with the pure culture were recorded in the AnBDR with 300 mL culture medium (total volume 2.3 L) at pH 5.2 and a glucose loading rate of 2.87 g/L.h. These results are about 2.3 and 1.3-fold higher than those achieved in the same bioreactor with 500 mL liquid medium and with the same glucose consumption rate. Therefore, our experimentations and a short review of the literature reported in this paper emphasize the relevance of performing bioreactors with high L/G transfer. [less ▲]

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See detailImprovement of foaming properties of whey protein products by enzymatic hydrolysis of the associated fat fraction
Blecker, Christophe ULg; Lamberti, I.; Sensidoni, A. et al

Conference (1996, March)

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See detailImprovement of Gc-Rich Template Amplification by Inverse Pcr
Moreau, Alain; Duez, Colette ULg; Dusart, Jean

in BioTechniques (1994), 17(2), 232-4

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See detailImprovement of genetic evaluation systems for maternally influenced traits and multi-breed livestock populations
Vanderick, Sylvie ULg

Doctoral thesis (2017)

Animal breeding programs are designed to genetically improve livestock populations over many generations to enhance farm sustainability and competitiveness. Genetic improvement is achieved by selecting ... [more ▼]

Animal breeding programs are designed to genetically improve livestock populations over many generations to enhance farm sustainability and competitiveness. Genetic improvement is achieved by selecting genetically superior animals, based on estimated breeding values, to be the parents of the next generation. These estimated breeding values are calculated by solving mixed model equations characterizing appropriate statistical genetic evaluation models. To guarantee effective genetic selection, genetic evaluation models must be tailored to the specific characteristics of the traits and population under evaluation. This PhD thesis focused on the development of genetic evaluation models suitable for categorical maternally influenced traits and for multi-breed populations. Appropriate genetic animal models were developed and assessed: (1) for two categorical maternally influenced traits based on calving ease scores from Walloon Holstein dairy cattle and on lamb survival data from a New Zealand sheep population; (2) for two multi-breed populations based on milk yield records of New Zealand purebred and crossbred dairy cattle, and on purebred and crossbred calving ease scores from Walloon Belgian Blue and Holstein cattle. Results showed that (1) fitting maternal effects was required to avoid biasing the estimated breeding values, and there was no clear advantage in using non-linear mixed models instead of linear mixed models for the genetic analysis of the two categorical maternal traits studied; (2) breed-dependent breeding values could be estimated using the proposed multi-breed models, and that combining purebred and crossbred data had a positive influence on the accuracy of the breeding values of purebred animals. Finally, part of the research presented in this thesis contributed to the development of the genetic evaluation systems currently used in Walloon Region of Belgium and in New Zealand. [less ▲]

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See detailImprovement of He ion induced SiGe layer relaxation by a thin Si:C layer
Buca, D.; Trinkaus, H.; Holländer, B. et al

Conference (2008)

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See detailImprovement of inland navigation in developping countries: the training center of Palembang (Sumatra, Indonesia), an example of transfer of technology through education
Marchal, Jean ULg

in Bulletin des Séances de l’Académie Royale des Sciences d’Outre-Mer = Mededelingen der Zittingen van de Koninklijke Academie voor Overzeese Wetenschappen (1997), Nouvelle Série 42(4)(1er trimestre), 10

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See detailImprovement of insulin-induced glucose disposal in obese patients with NIDDM after 1-wk treatment with d-fenfluramine.
Scheen, André ULg; Paolisso, G.; Salvatore, T. et al

in Diabetes Care (1991), 14(4), 325-32

OBJECTIVE: To study the short-term effects of the serotoninergic anorectic drug d-fenfluramine on insulin-induced glucose disposal. RESEARCH DESIGN AND METHODS: A randomized double-blind placebo ... [more ▼]

OBJECTIVE: To study the short-term effects of the serotoninergic anorectic drug d-fenfluramine on insulin-induced glucose disposal. RESEARCH DESIGN AND METHODS: A randomized double-blind placebo-controlled crossover trial with 1-wk treatment periods (2 x 15 mg/day d-fenfluramine) was conducted. Twenty obese subjects, 10 with normal oral glucose tolerance and 10 with non-insulin-dependent diabetes mellitus (NIDDM), were all treated with a weight-maintaining diet. Euglycemic-hyperinsulinemic glucose clamps with measurement of glucose kinetics with D-[3-3H]glucose were performed at either two (patients without NIDDM, 0.05 and 0.10 U.kg-1.h-1) or three (patients with NIDDM, 0.05, 0.10, and 0.50 U.kg-1.h-1) insulin delivery rates. RESULTS: In the nondiabetic subjects, no significant changes in any metabolic or hormonal parameter were measured in the basal state or during the clamp despite a slight reduction in body weight (-1.2 +/- 0.5 kg, P less than 0.05). In the diabetic patients, no significant changes in body weight or basal plasma insulin levels were observed, but fasting blood glucose levels (8.0 +/- 0.8 vs. 9.4 +/- 1.1 mM, P less than 0.005) and plasma free fatty acid concentrations (1150 +/- 227 vs. 1640 +/- 184 microM, P less than 0.05) were significantly reduced after d-fenfluramine compared with placebo. During the clamp, insulin metabolic clearance rate (MCR) was similar after both placebo and d-fenfluramine; endogenous (hepatic) glucose production was similarly and almost completely suppressed, whereas glucose disposal was remarkably enhanced after d-fenfluramine (average increase of glucose MCR 35 +/- 12%, P less than 0.02). CONCLUSIONS: Whatever the mechanism(s) involved, a 1-wk treatment with d-fenfluramine induces better blood glucose control and improves insulin sensitivity in obese patients with NIDDM independent of significant weight reduction; this last effect is not present in obese subjects with normal oral glucose tolerance. [less ▲]

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See detailImprovement Of Inulin Hydrolysis Yeast-Cell Reactor By Mutants Selection
Thonart, Philippe ULg; Weber, Dominique ULg; Rikir, R.

in Applied Biochemistry and Biotechnology (1988), 17

Detailed reference viewed: 5 (0 ULg)