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See detailInvestigations on PrP and PrPres in porcine brain and in stimufol preparations
Degand, Guy ULg; Remy, Benoit; Fotsing, Lucas ULg et al

in Proceedings: 20th Annual Meeting A.E.T.E (2004)

Detailed reference viewed: 19 (1 ULg)
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See detailInvestigations on Surra-induced lymphopoenia in a murine model
Antoine-Moussiaux, Nicolas ULg; Cornet, Anne ULg; Cornet, et al

Conference (2009, March)

Detailed reference viewed: 14 (3 ULg)
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See detailInvestigations on the development of the health status of harbour seals in the year of the PDV seal die-off in 2002
Siebert, Ursula; Fonfara, Sonja; Hasselmeier, Ilka et al

Poster (2004, March 31)

More than 21,500 harbour seals were killed by Phocine Distempter Virus in the North Sea and adjacent waters in 2002. Of those more than 3,340 seals were found dead on the coast of Schleswig-Holstein ... [more ▼]

More than 21,500 harbour seals were killed by Phocine Distempter Virus in the North Sea and adjacent waters in 2002. Of those more than 3,340 seals were found dead on the coast of Schleswig-Holstein. After the second seal die-off had ceased, seals were captured alive for a health check and also stranded seals were examined for their health status. Blood status and chemistry tests were performed, microbiological, parasitological, histological, serological and cytological investigations were conducted. During the first catch after the seal die-off animals seemed to be in clinically good condition although hematological disturbances (leucocytosis as well as leucopenia) were detected. Bacteriologically, Bordetella bronchisptica was isolated, a bacterium which was exclusively cultured during the seal die-off. At later catches hematological values normalized and also the normal bacterial flora was cultured from vagina and anus. The serological investigations for morbillivirus-specific antibodies revealed positive titers in 100% of the seals. Morphologically, there was no evidence for a continuing morbillivirus infection by both, histology and immunocytochemistry. The pathomorphological changes were similar to those before the epizootic including the predominance of parasitic and bacterial bronchopneumonia, emaciation and dermatitis. Contrary to the first seal die-off in 1988/89 an increased number of large skin wounds on the ventral side and infections of the umbilicus were not seen. This may indicate that the seal population in Schleswig-Holstein was generally in better health condition at the second seal die-off compared to the first one. The continued investigations will allow a further assessment of the development of the seal population in the Wadden Sea. [less ▲]

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See detailInvestigations on the mechanisms underlying the thymotropic properties of the growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis.
Goffinet, Lindsay ULg; Bodart, Gwennaëlle ULg; Renard, Chantal et al

Poster (2011, November 18)

Background. The thymus is responsible for thymopoiesis, i.e. the generation of a diverse and self-tolerant T-cell repertoire including self-antigen specific natural regulatory cells. We have shown that ... [more ▼]

Background. The thymus is responsible for thymopoiesis, i.e. the generation of a diverse and self-tolerant T-cell repertoire including self-antigen specific natural regulatory cells. We have shown that two parameters of thymopoiesis, thymic output of new T cells (estimated by sjTREC frequency) and intrathymic proliferation of T-cell precursors (estimated by sj/Dβ TREC ratio) are severely reduced in adult patients with GH deficiency (AGHD) and are restored by GH injections at physiological doses. In patients with AGHD, there is a very positive correlation between sjTREC frequency and plasma concentrations of IGF-1, the principal mediator of GH action (1). Treatment of HIV+ patients with high pharmacological doses of GH is associated with increased thymic mass and output of circulating naïve and total CD4+ T cells (2). In addition, previous studies have suggested thymic epithelial cells (TEC) and/or thymocytes (thymic T cells) could transcribe the GH gene (3). Objectives and hypothesis. These studies analysed the question of GH transcription and regulation in primary cultures of human (h) TEC. We also investigated the hypothesis that the thymotropic properties of the somatotrope GH/IGF-1 axis could be mediated by thymic interleukin 7 (IL-7), which plays a crucial role in promoting V(D)J recombination at the TCR locus. Results. Primary hTEC cultures were treated with natural secretagogues of pituitary GH, GH releasing hormone (GHRH) and ghrelin. Using sensitive RT-qPCR, we detected neither any transcript of GH or GHV (placental GH variant) in cultured hTEC, nor any transcript of PIT1, the specific transcription factor of pituitary GH. Similarly, the protein GH was detected neither in the cytoplasm nor in the supernatant of cultured hTEC. Only at 1 nM, GH treatment enhanced IGF1 transcription by cultured hTEC. Of high interest, treatment with GH, ghrelin and IGF-1 promoted IL7 transcription by cultured hTEC, but only IGF-1 and epidermal growth factor (EGF) markedly stimulated IL-7 secretion by hTEC in a dose- and time-dependent manner. The specificity of IGF-1 action was demonstrated by its inhibition after treatment with αIR3, a monoclonal antibody against the type 1 IGF receptor. Conclusions and perspectives. Since primary cultures of hTEC neither transcribe nor secrete any significant amount of GH, the thymotropic effects of the GH/IGF-1 axis seem to depend only on systemic endocrine GH. Local thymic IGF-1 could partially mediate GH action within the thymus and act upon thymopoiesis in parallel with systemic IGF-1. Most importantly, thymic IL-7 appears to be an important mediator of the thymotropic properties of the GH/IGF-1 axis. Further knowledge in this domain will be gained with the use and supplementation of Ghrh-/- mice that will be soon available in our laboratory. References 1. Morrhaye G. et al., PLoS ONE 2009, 4:e5668. 2. Napolitano LA et al. J Clin Invest 2008, 118:1085. 3. Smaniotto S et al., Endocrinology 2005, 146:3005. 4. Taub DD, Murphy WJ and Longo DL. Curr Opin Pharmacol 2010, 10:408. (Supported by F.R.S.-FNRS and a Pfizer Independent Research Grant.) [less ▲]

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See detailInvestigations on the Protein Distribution in the Two-Phase System Dextran + PEG + Water
Connemann, M; Gaube, J; Keil, B et al

in DECHEMA Annual Meeting of Biotechnologists : Karlsruhe, 01 au 03 juin 1992 (1992)

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See detailLes investigations psychologiques en psychiatrie clinique
Mormont, Christian ULg; Servais, Jean-François

in Revue Médicale de Liège (1973), 28(17), 612-614

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See detailInvestigations sur les protéines placentaires extraites des cotylédons fœtaux du Cervus elaphus
Fondja, E.; Okuyama, M.; Petrova, A. et al

Poster (2012, February)

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See detailInvesting in the Future
Pahud de Mortanges, Charles ULg

E-print/Working paper (2015)

This paper attempts to address the challenges of how to invest in Synthetic Biology firms, most of which are relatively new start-ups and unprofitable. Valuing an early-stage firm with only a brief ... [more ▼]

This paper attempts to address the challenges of how to invest in Synthetic Biology firms, most of which are relatively new start-ups and unprofitable. Valuing an early-stage firm with only a brief operating history, little or no operating profit (or even revenue), and an immature and untested business model, could be a formidable challenge. We propose a limited number of quantitative, and a larger number of qualitative criteria. An investor may consider these when faced with analyzing a new untried business, but one he/she believes has considerable potential for success in the future. [less ▲]

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See detailInvestir dans la durabilité des productions porcines : un chantier wallon.
Picron, Pascale ULg

Article for general public (2012)

Detailed reference viewed: 42 (11 ULg)
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See detailInvestir en Chine. Enjeux, Modalités d'investissement, Aspects fiscaux. (Organisation scientifique)
Richelle, Isabelle ULg

Scientific conference (2014, March 27)

La veille de l'arrivée en Belgique du Président de la République populaire de Chine, alors qu'un important accord d'investissements est en cours de négociation entre l'Union européenne et la Chine, une ... [more ▼]

La veille de l'arrivée en Belgique du Président de la République populaire de Chine, alors qu'un important accord d'investissements est en cours de négociation entre l'Union européenne et la Chine, une nouvelle convention fiscale nous liant à la Chine vient d'entrer en vigueur. L'objectif de ce colloque est de donner aux entreprises et à leurs conseils juridiques et fiscaux un ensemble de "clés" leur permettant de comprendre la Chine, afin d’optimaliser leurs investissements et d'en analyser de manière efficace les différentes problématiques fiscales. La réussite d'un investissement suppose en effet une bonne connaissance de ses interlocuteurs. La bonne application de la loi fiscale implique d'en appréhender les concepts sous-jacents. Différents acteurs ayant une expertise directe de la Chine nous font part de leur expérience. [less ▲]

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See detailInvestir et gérer le transport public urbain ?
Gautier, Axel ULg

Conference given outside the academic context (2015)

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See detailInvestir ou mourir, il faut choisir…
Choffray, Jean-Marie ULg

Book published by Kindle Edition, Amazon.com (2016)

Investir : c’est croire en l’avenir. C’est renoncer en partie au présent pour donner vie au futur. C’est tourner le dos aux « bouffeurs d’espoir » et à l’illusoire confort du statu quo. Enfin, et surtout ... [more ▼]

Investir : c’est croire en l’avenir. C’est renoncer en partie au présent pour donner vie au futur. C’est tourner le dos aux « bouffeurs d’espoir » et à l’illusoire confort du statu quo. Enfin, et surtout, c’est oser « oser » ! La distance séparant le discours public de la performance économique avérée suffit à démontrer l’incompréhension des mécanismes de création de richesse de ceux qui sont censés en avoir la maîtrise et/ou les mettre en œuvre. Il est peu de domaines où les illusions, et autres idées fausses, ont un succès tel qu’elles amènent à s’interroger sur le profit que d’aucuns pourraient en tirer… L’objet de cet ouvrage est de partager le fruit d’une réflexion menée sur le thème de l’investissement, forme proéminente et condition première de l’activité économique, au moment où certains s’interrogent sur son encadrement et cherchent à en limiter la liberté. Il aborde les bouleversements technologiques les plus significatifs ; l’art et la science d’investir avec Internet ; la recherche d’opportunités nouvelles ; et, se termine par quelques observations et souhaits quant à « l’état » du monde ! [less ▲]

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See detailInvestir ou travailler en France
Leleu, Yves-Henri ULg; Brauns, Patrick; Lacourt, Alain et al

Book published by Anthémis - LGDJ (2010)

Detailed reference viewed: 40 (13 ULg)
See detailLes investissements directs et les échanges commerciaux entre la Belgique et les pays arabes
Artige, Lionel ULg

in Khader, Bichara; Roosens, Claude (Eds.) Belges et Arabes. Voisins distants, partenaires nécessaires. (2004)

Detailed reference viewed: 17 (2 ULg)
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See detailInvestissements étrangers et milieu local : bilan et perspectives, conclusion d’un colloque
Merenne-Schoumaker, Bernadette ULg

in Goueset, Vincent (Ed.) Actes du colloque de Rennes octobre 1998 (1999)

Conclusions of a symposium on the role of foreign investments in the local development

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See detailLes investisseurs institutionnels dans les Maisons de luxe familiales belges: entre diabolisation et sacralisation
Riguelle, France ULg; Van Caillie, Didier ULg

E-print/Working paper (2012)

Abstract : Belgian family luxury Houses are increasingly confrontated to a problem of independence caused by the growing influence of great financial groups and of private investment funds, on the one ... [more ▼]

Abstract : Belgian family luxury Houses are increasingly confrontated to a problem of independence caused by the growing influence of great financial groups and of private investment funds, on the one hand, and by a problem of image due to their Belgian origin, on the other hand. Nevertheless, their growing need for internationalization in order to counter the threats of the market and to seize opportunities leads them to concede one part of their control to institutional investors. The interest of this research is to study the potential impact, as perceived by the leaders of Belgian luxury Houses, of the venue of public institutional investors in their capital structure. We show that this perceived impact oscillates between sacralization and diabolisation of public institutional investors. [less ▲]

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See detailThe investment casting and processing of cobalt-base and cobalt-bearing superalloys
Lamberigts, M.; Lecomte-Beckers, Jacqueline ULg; Walmag, G. et al

in Second Congress Cobalt Metallurgy and Uses (1985)

To cope with the demands of engine manufacturers and other users, superalloys have been brought to work in service at temperatures which represent a very substantial fraction of their melting point. In ... [more ▼]

To cope with the demands of engine manufacturers and other users, superalloys have been brought to work in service at temperatures which represent a very substantial fraction of their melting point. In addition to high temperature capability, they must exhibit mechanical strength, not only under static, but also under cyclic stressing conditions, and offer appropriate oxidation and corrosion resistance. This can only be achieved by tailoring their chemistry and processing conditions to the particular needs of the application under consideration. The evolution of component design and alloy chemistry, and some compositional effects and processing improvements in cast Ni-base superalloys are discussed. [less ▲]

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See detailInvestor Sentiment, Mutual Fund Flows and its Impact on Returns and Volatility
Beaumont, Rob; Frijns, Bart; Lehnert, Thorsten et al

in Managerial Finance (2008), 34(11), 772-785

Detailed reference viewed: 64 (14 ULg)
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See detailL'inviolabilité du domicile
Souply-Pierard, Fernand ULg

Learning material (2011)

L’inviolabilité du domicile est une notion fondamentale et incontournable dans un État démocratique digne de ce nom. Il s’agit d’un principe impératif mais pas indérogeable. En effet, l’État peut, dans ... [more ▼]

L’inviolabilité du domicile est une notion fondamentale et incontournable dans un État démocratique digne de ce nom. Il s’agit d’un principe impératif mais pas indérogeable. En effet, l’État peut, dans des cas relativement restreints, violer le domicile d’une personne, ceci uniquement en vertu d’une loi (au sens strict) et dans les formes qu’elle prescrit. Une violation illégale du domicile constituerait une entrave grave aux droits fondamentaux du citoyen. [less ▲]

Detailed reference viewed: 48 (6 ULg)