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See detailMensonge et vérité sur la vibrotonie
Bruyère, Olivier ULg

Scientific conference (2012, March 27)

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See detailMental arithmetic in children with learning disabilities : the adaptative use of approximate calculation in an addition verification task.
Rousselle, Laurence ULg; Noël, Marie-Pascale

in Journal of Learning Disabilities (2008), 41

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See detailMental health and emotions in couples with an alcoholic member
Dethier, Marie ULg; Counerotte, Christelle; Blairy, Sylvie ULg

Poster (2009, June 03)

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See detailMental health inside the primary care ; a different mental health ?
Jamoulle, Marc ULg; Roland, Michel

Conference (1994, July 21)

Family medicine is the first level of help for patients facing illness or ill-results of the practice of medicine. Settler, listener, defender, the general practitioner occupies a potent position but an ... [more ▼]

Family medicine is the first level of help for patients facing illness or ill-results of the practice of medicine. Settler, listener, defender, the general practitioner occupies a potent position but an uncomfortable one. It is necessary to understand the highly complicated position of the family doctor in western society before discussing mental health in the field of primary care. The forces and weaknesses of the family doctor's position will be summarized. The various mental health classifications will be tied to their conceptual patterns. [less ▲]

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See detailThe mental illness concept from the learning theory point of view
Richelle, Marc ULg

in Simhandl, Christian (Ed.) Klassifikations-probleme in der psychiatrie (1990)

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See detailMental Powers in Early Modern Philosophy. British Journal for the History of Philosophy. Special Issue
Boccaccini, Federico ULg; Marmodoro, Anna

Book published by Routledge (in press)

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See detailMental Retardation with Blepharo-Naso-Facial Abnormalities and Hand Malformations: A New Syndrome?
Van Maldergem, Lionel ULg; Wetzburger, C.; Verloes, Alain ULg et al

in Clinical Genetics (1992), 41(1), 22-4

A syndrome involving facial abnormalities (telecanthus, epicanthus, broad flattened nose, large inverted W-shaped mouth and malformed ears), malformed extremities (camptodactyly, clinodactyly ... [more ▼]

A syndrome involving facial abnormalities (telecanthus, epicanthus, broad flattened nose, large inverted W-shaped mouth and malformed ears), malformed extremities (camptodactyly, clinodactyly, interdigital webbing and joint hyperlaxity) and mental retardation is described in a girl at birth and at 11 years old. A comparison with Pashayan-Pruzansky syndrome, fetal alcohol syndrome, VATER association, Marden-Walker syndrome and Tel-Hashomer syndrome is discussed. We suggest this patient represents a new malformation syndrome or an extreme phenotypic variant of one of the above-mentioned syndromes. [less ▲]

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See detailMental Time Travel in First Degree Relatives of Schizophrenia Patients
Boulanger, Marie ULg; Wagener, Aurélie ULg; Duke, Géraldine et al

Poster (2013, July 23)

Introduction. Genetic and environmental factors are important to explain the causation of schizophrenia. The families’ studies can help us to better understand the genetic influence. Indeed, the cognitive ... [more ▼]

Introduction. Genetic and environmental factors are important to explain the causation of schizophrenia. The families’ studies can help us to better understand the genetic influence. Indeed, the cognitive deficits found in the unaffected biological relatives of schizophrenia patients parallel the deficits found in patients. These deficits might be putative endophenotypic markers of schizophrenia, ie. characteristics that mark the presence of a genetic predisposition to a certain disease or disability, in this case, the schizophrenia (Sitskoorn et al., 2004). In this way, previous studies reported that compared to healthy controls (HC), the relatives show cognitive impairments that are similar but milder degree than those of schizophrenia patients (SCh). The deficits affect cognitive functions such as verbal memory, attention and executive function; hence the interests to take into account the endophenotypic markers. To our knowledge, no study has yet assessed the abilities to mental time travel in the relatives despite that this cognitive function is impairment in SCh (Cuervo-Lombard et al., 2007; D’argembeau et al., 2008; Wood and Brewin, 2006). The mental time travel allows individuals both to retrieve past personal autobiographical information and to project into future personal events. Further, it is related to the continuity and the stability of identity, which has also been described as fragmented instable or discontinuous in SCh (Boulanger et al., submitted; deBonis et al., 1995; Nieznanski, 2004). Consequently, the ability to mental time travel could be a relevant endophenotypic marker. Method. 31 SCh, 33 relatives and 31 HC generated both ten past memories and ten future events in response to cue words from TeMA (a French version of AMT). In parallel, they completed cognitive tests, such as the Stroop Color-Word Test, the Trail Making Test, the Digit Span Backward and Forward Test (WAIS-III) and questionnaires which evaluated mood disturbances such as BDI-II and STAI-Y. Finally, participants were asked to respond to a short version of LABEL, which measured identity stability. Results. SCh showed deficits on all measures in comparison to HC. However no significant differences emerged between relatives and HC on measures of time travel. Nevertheless, differences were found for interference score (Stroop-Color-Words Test) and score on part B from TMT, as well as relatives and SCh. Discussion. Despite the fact that the majority of the relatives’ scores on different measures are not significant in comparison to HC and SCh, their results situated between the results of both groups. These results are discussed in the light of previous research. [less ▲]

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See detailThe Mental Whiteboard Hypothesis on Serial Order in Working Memory
Abrahamse, Elger; Van Dijck, Jean-Philippe; Majerus, Steve ULg et al

in Frontiers in Human Neuroscience (2014), 8

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See detailMente e metafisica in Franz Brentano
Boccaccini, Federico ULg

Conference (2008, February)

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See detailLes mentions autographes dans les missives du duc de Bourgogne Philippe le Bon
Dumont, Jonathan ULg; Marchandisse, Alain ULg

in Dumézil, Bruno; Vissière, Laurent (Eds.) Epistolaire politique II : « Authentiques et autographes (IVe–XVIe siècles) » (2012, January 27)

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See detailLes mentions d'auteurs antiques dans les chansons de geste françaises
Henrard, Nadine ULg

in Haugeard, Philippe; Ribémont, Bernard (Eds.) Chanson de geste et savoirs savants (in press)

Les origines savantes ou populaires des épopées françaises médiévales ont longtemps fait débat. Il s'avère que ces textes contiennent un très grand nombre de références à des personnages issus de ... [more ▼]

Les origines savantes ou populaires des épopées françaises médiévales ont longtemps fait débat. Il s'avère que ces textes contiennent un très grand nombre de références à des personnages issus de l’Antiquité qui témoignent d’une formation scolaire chez les auteurs des chansons. Sur la base d'un examen de l'ensemble du corpus, cette étude s'intéresse plus particulièrement aux mentions explicites faites à des auteurs antiques, qu'ils soient grecs (Homère, Aristote, Platon) ou latins (Virgile, Ovide, César, Caton, Sénèque). En tenant de déterminer les traditions qui ont pu nourrir l'inspiration des auteurs des chansons de geste, elle s'emploie à définir les situations dans lesquelles les références en question apparaissent, et s’interroge sur les finalités que poursuivent les poètes à travers l’évocation des auteurs antiques, dont certains, comme César ou Virgile, sont davantage restés dans les mémoires pour des éléments réels ou imaginaires de leur vie plutôt que pour leur œuvre. [less ▲]

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See detailLes mentions du mandat de perquisition comme protection des droits de défense
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2006)

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See detailMentor 2 (1986-1990). Guide bibliographique de la religion grecque. Bibliographical Survey of Greek Religion
Motte, André ULg; Pirenne-Delforge, Vinciane ULg; Wathelet, Paul ULg

Book published by Centre International d'Etude de la Religion Grecque Antique (1998)

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See detailMentor. Guide bibliographique de la religion grecque. Bibliographical Survey of Greek Religion
Motte, André ULg; Pirenne-Delforge, Vinciane ULg; Wathelet, Paul ULg

Book published by Centre International d'Etude de la Religion Grecque Antique (1992)

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See detailLe menu des jeunes Moineaux domestiques, Passer domesticus L., et espagnols, Passer hispaniolensis TEMM., en Oranie.
Metzmacher, Maxime ULg

in Cahiers d’Ethologie Appliquée (1983), 3

The composition and the structure of the nestling sparrows were studied in the north-west of Algeria. The nestling's food of the two sparrows consisted mainly of animal food in the beginning of the ... [more ▼]

The composition and the structure of the nestling sparrows were studied in the north-west of Algeria. The nestling's food of the two sparrows consisted mainly of animal food in the beginning of the nestling period, the vegetable fraction of the diet become more important at the end of this period. Preys hierarchy can vary with nestling age, colony situation and season. The two sparrows, and their recognised age-classes, have similar diet structure. The distribution of preys between the different taxa revealed that the sparrows are generalist predators. The spanish sparrow,however, exhibit sometimes a strong specialisation. [less ▲]

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See detailUn menu qui pèse dans la balance climatique
Ozer, Pierre ULg; Perrin, Dominique ULg

Article for general public (2009)

Un menu qui pèse dans la balance climatique Prenons un menu un brin festif: potage, plat, dessert. Calculons : ensemble, les denrées parcourent 218 000 kilomètres avant de tomber dans notre assiette. Et ... [more ▼]

Un menu qui pèse dans la balance climatique Prenons un menu un brin festif: potage, plat, dessert. Calculons : ensemble, les denrées parcourent 218 000 kilomètres avant de tomber dans notre assiette. Et émettent 37,5 kg de CO2. À ce prix, l’avion est-il vraiment inéluctable pour transporter la nourriture? [less ▲]

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See detailMepolizumab treatment in patients with severe eosinophilic asthma.
Ortega, Hector G.; Liu, Mark C.; Pavord, Ian D. et al

in The New England journal of medicine (2014), 371(13), 1198-207

BACKGROUND: Some patients with severe asthma have frequent exacerbations associated with persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled glucocorticoids with or ... [more ▼]

BACKGROUND: Some patients with severe asthma have frequent exacerbations associated with persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled glucocorticoids with or without oral glucocorticoids. METHODS: In this randomized, double-blind, double-dummy study, we assigned 576 patients with recurrent asthma exacerbations and evidence of eosinophilic inflammation despite high doses of inhaled glucocorticoids to one of three study groups. Patients were assigned to receive mepolizumab, a humanized monoclonal antibody against interleukin-5, which was administered as either a 75-mg intravenous dose or a 100-mg subcutaneous dose, or placebo every 4 weeks for 32 weeks. The primary outcome was the rate of exacerbations. Other outcomes included the forced expiratory volume in 1 second (FEV1) and scores on the St. George's Respiratory Questionnaire (SGRQ) and the 5-item Asthma Control Questionnaire (ACQ-5). Safety was also assessed. RESULTS: The rate of exacerbations was reduced by 47% (95% confidence interval [CI], 29 to 61) among patients receiving intravenous mepolizumab and by 53% (95% CI, 37 to 65) among those receiving subcutaneous mepolizumab, as compared with those receiving placebo (P<0.001 for both comparisons). Exacerbations necessitating an emergency department visit or hospitalization were reduced by 32% in the group receiving intravenous mepolizumab and by 61% in the group receiving subcutaneous mepolizumab. At week 32, the mean increase from baseline in FEV1 was 100 ml greater in patients receiving intravenous mepolizumab than in those receiving placebo (P=0.02) and 98 ml greater in patients receiving subcutaneous mepolizumab than in those receiving placebo (P=0.03). The improvement from baseline in the SGRQ score was 6.4 points and 7.0 points greater in the intravenous and subcutaneous mepolizumab groups, respectively, than in the placebo group (minimal clinically important change, 4 points), and the improvement in the ACQ-5 score was 0.42 points and 0.44 points greater in the two mepolizumab groups, respectively, than in the placebo group (minimal clinically important change, 0.5 points) (P<0.001 for all comparisons). The safety profile of mepolizumab was similar to that of placebo. CONCLUSIONS: Mepolizumab administered either intravenously or subcutaneously significantly reduced asthma exacerbations and was associated with improvements in markers of asthma control. (Funded by GlaxoSmithKline; MENSA ClinicalTrials.gov number, NCT01691521.). [less ▲]

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See detailMepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis.
Gevaert, Philippe; Van Bruaene, Nicholas; Cattaert, Tom ULg et al

in Journal of Allergy and Clinical Immunology (The) (2011), 128(5), 989-9958

BACKGROUND: Approximately 85% of nasal polyps (NPs) in white subjects are characterized by prominent eosinophilia. IL-5 is the key driver of eosinophilic differentiation and survival. OBJECTIVE: We sought ... [more ▼]

BACKGROUND: Approximately 85% of nasal polyps (NPs) in white subjects are characterized by prominent eosinophilia. IL-5 is the key driver of eosinophilic differentiation and survival. OBJECTIVE: We sought to investigate the therapeutic potential of inhibiting IL-5 with a humanized mAb as treatment for severe nasal polyposis. METHODS: Thirty patients with severe nasal polyposis (grade 3 or 4 or recurrent after surgery) refractory to corticosteroid therapy were randomized in a double-blind fashion to receive either 2 single intravenous injections (28 days apart) of 750 mg of mepolizumab (n = 20) or placebo (n = 10). Change from baseline in NP score was assessed monthly until 1 month after the last dose (week 8). Computed tomographic scans were also performed at week 8. RESULTS: Twelve of 20 patients receiving mepolizumab had a significantly improved NP score and computed tomographic scan score compared with 1 of 10 patients receiving placebo at week 8 versus baseline. CONCLUSION: Mepolizumab achieved a statistically significant reduction in NP size for at least 1 month after dosing in 12 of 20 patients. IL-5 inhibition is a potential novel therapeutic approach in patients with severe eosinophilic nasal polyposis. [less ▲]

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