Atypical myopathy (myoglobinuria): 5 cases-based questions.

Scientific conference (2008, April)

Case-based questions ... and answers!

Atypical Myopathy In Grazing Horses: A First Exploratory Data Analysis

in Veterinary Journal (2009), 180(1),

Atypical recurrent varicella in 4 patients with hemopathies.

in Journal of the American Academy of Dermatology (2003), 48(3), 442-7

Relapsing varicella may occur in children with HIV infection and more rarely in younger adults. Our aim was to report unusual clinical, histologic, and virologic aspects of 4 elderly patients with ... [more ▼]

Relapsing varicella may occur in children with HIV infection and more rarely in younger adults. Our aim was to report unusual clinical, histologic, and virologic aspects of 4 elderly patients with malignant hemopathies who had an unusual form of recurrent varicella develop. Conventional microscopy, immunohistochemistry, and in situ hybridization were applied to smears and skin biopsy specimens. The patients presented a few dozen, scattered, large, papulovesicular lesions with central crusting. No zoster-associated pain or dermatomal distribution of the lesions was noted. Conventional microscopy revealed vascular changes and epidermal alterations typical for alpha-herpes virus infection. The varicella zoster virus major viral envelope glycoproteins gE and gB, and the immediate-early varicella zoster virus IE63 protein and the corresponding genome sequence for gE were detected on Tzanck smears; they were localized in endothelial cells and keratinocytes on skin biopsy specimens. The varicella zoster virus infection in endothelial cells, the vascular involvement, and the widespread distribution of the lesions suggest that the reported eruptions are vascular rather than neural in origin. These findings invalidate the diagnosis of herpes zoster but strongly support the diagnosis of recurrent varicella in an indolent and yet unreported presentation. Furthermore, these eruptions differ from relapsing varicella in children and young adults by the age of the patients, the paucity of clinical lesions, the larger diameter of the lesions and their peculiar clinical aspect, the significantly longer time interval between primary varicella and the recurrence, the prolonged healing time of the lesions, their mild disease course, and the fact that all the lesions are in the same stage of development. [less ▲]

Atypical symptoms of GORD in Belgium: Epidemiological features, current management and open label treatment with 40 mg esomeprazole for one month

in Acta Gastro-Enterologica Belgica (2006), 69(2, Apr-Jun), 203-208

Frequency of atypical symptoms in patients suffering from gastro-oesophageal reflux disease (GORD) is not well known, and the optimal management of such symptoms has not been well established. Our aims ... [more ▼]

Frequency of atypical symptoms in patients suffering from gastro-oesophageal reflux disease (GORD) is not well known, and the optimal management of such symptoms has not been well established. Our aims were to set up an observatory of these atypical symptoms of GORD in Belgium and to study the efficacy of one month treatment with esomeprazole 40 mg. Patients and methods : Gastroenterologists; participating in this observational survey were asked to register every new outpatient with symptoms of GORD during a period of 20 consecutive working days. All patients who reported predominant presence of atypical manifestations of GORD were documented and characterized more in detail. In patients with dominant chest pain or ENT symptoms, a treatment with esomeprazole 40 mg daily during 4 weeks was proposed. Results : 90 gastroenterologists included 2864 patients consulting for symptoms suggestive of GORD, including 776 (27.1%) with dominant atypical symptoms. Endoscopy (performed in 2800 patients) showed significantly less oesophagitis in atypical than in typical GORD patients (68% vs. 81.1%; P < 0.0001). Management of atypical GORD patients appeared to be very heterogeneous. Overall 516/776 patients were included in the open phase of treatment with esomeprazole 40 mg, but data for analysis are only available in 228 patients. After one month, symptoms had disappeared in 57.1% and significantly improved in 26.6%. Conclusion : Atypical GORD represents a large number of consultations in gastroenterology in Belgium. It is associated with less endoscopic lesions than typical GORD. Its management is heterogeneous reflecting the lack of guidelines on this topic. Response rate after esomeprazole 40 mg for one month in this open uncontrolled trial was high. This result warrants confirmation in a placebo-controlled trial. [less ▲]

Au coeur de l'action : les agents ZEP

in Evaluation des premières zones d'éducation prioritaires en Comunauté française (Zones 2 & 3 : Bruxelles) (1993)

"Au commencement était le texte - Des rapports entre contraintes phrastiques et textuelles"

in Actes du XXIIème Congrès de linguistique et philologie romanes (2000)

Au cœur de la modernisation de la distribution : les stratégies spatiales des acteurs

in Desse, René-Paul (Ed.) Les nouveaux acteurs du commerce et leurs stratégies spatiales (1997)

In order to explain the recent changes in retailing, one must not simply study the facts, i.e. spatial and structural changes of the retail industry. It is also necessary to explain the process which ... [more ▼]

In order to explain the recent changes in retailing, one must not simply study the facts, i.e. spatial and structural changes of the retail industry. It is also necessary to explain the process which implies to study the spatial strategies of the actors. These are more numerous that they used to be. First, there are the initial partners i.e. the producers, the retail merchants and the consummers who have certainly change in the last 30 years. There is also the administration which is more and more concerned with the regulations and the organization of the sector. And, last but not least, the professionals of the commercial property business : the property developers, the investors and the technical advisers. What part are these actors playing in the retail industry ? How are their roles changing ? What are the strong points of their spatial strategies ? There are the issues of our paper which try to set up a synthetic table of the problem from informations gather together in both France and Belgium. [less ▲]

Au delà de l’irrationalité : vers une psychologique du phénomène de harcèlement moral.

in Cahiers Internationaux de Psychologie Sociale (2003), 48

De prime abord, les situations de harcèlement moral dégagent une impression d’irrationalité intense (Geuzaine & Faulx, 2000). Depuis notre position d’observateur extérieur, nous sommes face à un ensemble ... [more ▼]

De prime abord, les situations de harcèlement moral dégagent une impression d’irrationalité intense (Geuzaine & Faulx, 2000). Depuis notre position d’observateur extérieur, nous sommes face à un ensemble d’éléments qui heurtent la logique. Du point de vue de celui qui s’en sent victime, d’abord : une personne vit une situation d’abus sur son lieu de travail, elle nous décrit, dans un flot de détails, les agissements qu’elle subit et nous percevons l’intensité de son angoisse. Les affects sont à l’avant-plan, intenses et souvent désespérés. La personne se sent persécutée, bafouée, démolie, et pourtant tente obstinément de continuer à fonctionner dans une situation insupportable. Pourquoi ? Du point de vue de l’organisation, ensuite : le harcèlement moral, entre autres conséquences dommageables, entrave la productivité, augmente l’absentéisme, génère des surcoûts importants et détériore la qualité des produits et des services. Si un fonctionnement optimal et une bonne gestion des ressources humaines semblent un objectif profitable à l’organisation, comment le harcèlement moral peut-il s’y développer ? Lorsque l’on tente d’intégrer le « harceleur» au système compréhensif, l’irrationnel est de nouveau à l’avant-plan. En effet, les raisons qui amènent cette personne à développer un mode relationnel persécutoire ont beau être logiquement justifiées (« je veille à la qualité du travail et promeus l’excellence ». «cette personne ne répond pas aux critères », « c’est de mon devoir de la sanctionner ,«c’est pour qu’elle apprenne »), il n’en sert pas moins, même involontairement, des fins totalement irrationnelles : mettre en échec puis détruire psychologiquement une personne et l’évacuer du système professionnel en invoquant sa propre responsabilité, son déséquilibre, son inadaptation au travail. Pourquoi ? Le but de cet article est de présenter un modèle d’analyse qui permette de dépasser l’impression d’irrationalité qui se dégage des situations de harcèlement moral. Nous verrons qu’il existe une logique sous-jacente au processus de harcèlement moral; logique certes subjective et biaisée, mais à la base d’un système de comportements et d’attentes très influent. Après avoir exposé quelques repères théoriques, nous présenterons notre recherche et nos postulats méthodologiques. La partie consacrée à nos résultats s’articulera autour de deux axes : la présentation de certaines régularités parmi les situations de harcèlement moral et une réflexion sur l’aide que l’on peut proposer aux personnes qui en sont victimes. [less ▲]

Au fil du fleuve. Entretien avec Luc et Jean-Pierre Dardenne

in Revue belge du cinéma (1997), 41

Au fur et à mesure qu'elles se construisent, les trajectoires professionnelles divergent entre les sexes : l'exemple belge

in Formation Emploi : Revue Française de Sciences Sociales (1996), 93