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See detailAortic valve replacement in octogenarians: operative outcome and long-term results
Kolh, Philippe ULg; Kerzmann, Arnaud ULg; Jacquart, Julie ULg et al

in European Heart Journal (2005, September), 26(Suppl. 1), 676

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See detailAortic Valve Replacement in the Octogenarians: Perioperative Outcome and Clinical Follow-Up
Kolh, Philippe ULg; Lahaye, Laurent; Gérard, Paul ULg et al

in European Journal of Cardio - Thoracic Surgery (1999), 16(1), 68-73

OBJECTIVES: To determine long-term results of aortic valve replacement (AVR) in patients 80 years old or older, and assess the factors influencing perioperative outcome. METHODS: Data were reviewed on 83 ... [more ▼]

OBJECTIVES: To determine long-term results of aortic valve replacement (AVR) in patients 80 years old or older, and assess the factors influencing perioperative outcome. METHODS: Data were reviewed on 83 consecutive octogenarians, undergoing aortic valve replacement between 1992 and 1997. There were 66 women and 17 men (mean age: 82.8 years). Fifty-seven patients (69%) were in New York Heart Association (NYHA) class III-IV and six had previous myocardial infarction. Three patients had previous percutaneous aortic valvuloplasty. There were 19 urgent procedures (23%). Coronary artery bypass grafting (CABG) was performed on 21 patients (25%). Possible influence of preoperative and operative variables on early and late mortality was performed with univariate and multivariate statistical analysis, and survival was estimated with the Kaplan-Meier method. RESULTS: Operative mortality was 13% (9% for AVR, 24% for AVR-CABG). Postoperative complications were respiratory failure in 19 patients, atrial fibrillation in 19, hemodialysis in four, myocardial infarction in four and stroke in two patients. Five patients required pacemaker insertion for permanent atrioventricular block. Median hospital stay and intensive care unit stay were 19.8 +/- 12.2 days and 7.9 +/- 3.4 days, respectively. Multivariate predictors of hospital death (P < 0.05) were percutaneous aortic valvuloplasty, NYHA class IV, and urgent procedure. Mean follow-up was 26.5 months. Survival at 1, 2, and 5 years was 98.5 +/- 1.4% (63 patients at risk), 93.4 +/- 3.2% (47 patients at risk), and 78.2 +/- 6.9% (six patients at risk), respectively. Preoperative myocardial infarction and urgent procedure were independent predictors of late death. At most recent follow-up, 91% were angina free and 81% were in class I-II. CONCLUSIONS: Aortic valve replacement in octogenarians can be performed with acceptable mortality. These results stress the importance of early operation on elderly patients with aortic valve disease. Both long-term survival and functional recovery are excellent. [less ▲]

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See detailAortic valve surgery in octogenarians: predictive factors for operative and long-term results
Kolh, Philippe ULg; Kerzmann, Arnaud ULg; Honoré, Charles ULg et al

in European Journal of Cardio - Thoracic Surgery (2007), 31(4), 600-605

Objective: To assess factors influencing operative and tong-term outcome in octogenarians undergoing aortic valve surgery (AVR). Methods: Records of 220 consecutive octogenarians having AVR between 1992 ... [more ▼]

Objective: To assess factors influencing operative and tong-term outcome in octogenarians undergoing aortic valve surgery (AVR). Methods: Records of 220 consecutive octogenarians having AVR between 1992 and 2004 were reviewed, and follow-up obtained (99% complete). Of the group (mean age: 82.8 years; 174 females), 142 patients (65%) were in New York Heart Association (NYHA) class III-IV, 22 (10%) had previous myocardial infarction, 11 (5%) had previous coronary artery bypass grafting (CABG), and 8 (4%) had percutaneous aortic valvuloplasty. There were 44 urgent procedures (20%), and additional CABG was performed in 58 patients (26%). Results: Operative mortality was 13% (9% for AVR, 24% for AVR + CABG). Among the 29 patients who died, 14 (48%) were operated on urgently (32% mortality for urgent procedures). Causes of hospital death were respiratory insufficiency or infection in 16 patients (16/29 = 55%), myocardial, infarction in 8 (28%), stroke in 2 (7%), sepsis in 2 (7%), and renal failure in 1 (3%). Significant postoperative complications were atrial fibrillation in 48 patients (22%), respiratory insufficiency in 46 (21%), permanent atrio-ventricular bloc in 12 (5%), myocardial infarction in 10 (5%), hemodialysis in 4 (2%), and stroke in 4 (2%). Mean hospital and intensive care unit (ICU) stays were 17.6 +/- 5.2 and 6.9 +/- 3.4 days, respectively. Multivariate predictors (p < 0.05) of hospital death were urgent procedure, associated CABG, NYHA class IV, and percutaneous aortic valvuloplasty. Age, associated CABG, and urgent procedure were predictors of prolonged ICU stay. Mean follow-up was 58.2 months and actuarial 5-year survival was 73.2 +/- 6.9%. Age, preoperative myocardial infarction, urgent procedure, and duration of ICU stay were independent predictors of late death. Among 130 patients alive at follow-up, 91% were angina free and 81% in class I-II. Conclusions: AVR in octogenarians can be performed with acceptable mortality, although significant morbidity. These results stress the importance of early operation on elderly patients with aortic valve disease, avoiding urgent procedures. Associated coronary artery disease is a harbinger of poor operative outcome. Long-term survival and functional recovery are excellent. (c) 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved. [less ▲]

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See detailAortofemorographie par resonance magnetique nucleaire versus arteriographie conventionnelle: evaluation prospective.
NCHIMI LONGANG, Alain ULg; Brisbois, D.; Donkers, E. et al

in JBR-BTR : organe de la Societe royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR) (2002), 85(5), 246-51

PURPOSE: To determine how far MRA of lower limbs obviates the need for pre-therapeutic DSA. MATERIALS AND METHOD: Three-step 3-D gadolinium enhanced aortofemorography with a moving bed was prospectively ... [more ▼]

PURPOSE: To determine how far MRA of lower limbs obviates the need for pre-therapeutic DSA. MATERIALS AND METHOD: Three-step 3-D gadolinium enhanced aortofemorography with a moving bed was prospectively compared to DSA in 49 consecutive patients (40 males, 9 females; age range 38-80 years; mean age 64 years). According to Leriche and Fontaine's clinical gradation of lower limb ischemia, 5 patients were graded I, 37 graded II, 4 graded III, and 3 graded IV. Two observers graded stenoses for DSA and three for MRA. Cohen's kappa statistics were used to evaluate interobserver variability using MRA, as well as to compare MRA to DSA. In addition, sensitivity, specificity, positive and negative predictive values of MRA for the assessment of stenosis superior to 80% were calculated by using DSA as a gold standard, respectively for arterial trunks above and below the level of the knees. RESULTS: Overall accuracy of MRA was 92%. Comparison of DSA and MRA yielded a kappa value of 0.87 (0.95 for arterial trunks located above the level of the knees and 0.75 below). Interobserver agreement was very good. Sensitivity, specificity, positive and negative predictive values of MRA for the diagnosis of > 80% stenosis were respectively 98, 98, 85 and 99% above the level of the knees and 87, 91, 77 and 96% below the knees. CONCLUSION: MRA can be considered as valuable technique for the evaluation of peripheral arterial obstructive disease, especially for stenosis located above the level of the knees. [less ▲]

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See detailAortopexy reduces anastomosis stress after repair of coarctation.
Vazquez-Jimenez, J. F.; Sachweh, J. S.; Seipelt, R. et al

in Annals of Thoracic Surgery (2001), 72(1), 294-5

Restenosis after repair of coarctation with hypoplastic distal aortic arch is an important complication. Complete removal of ductal tissue, resection of isthmus area, and side-to-side arterioplasty of the ... [more ▼]

Restenosis after repair of coarctation with hypoplastic distal aortic arch is an important complication. Complete removal of ductal tissue, resection of isthmus area, and side-to-side arterioplasty of the distal aortic arch leads to a wide distance between the aortic arch and descending aorta; therefore, the anastomosis may remain under tension, increasing risk of restenosis. To reduce the tension, aortopexy of the descending aorta was used. The operative technique and the results in 16 neonates and infants are presented. [less ▲]

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See detailAP 11, 15 (Ammianos): Dreifacher Schutz vor dem Tode
Vanhaegendoren, Koen ULg

in Eranos (2006), 104(2), 113-116

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See detailAP and MN-centric Mobility Prediction: A Comparative Study Based On Wireless Traces
François, Jean-Marc; Leduc, Guy ULg

in Lecture Notes in Computer Science (2007, May), 4479

The mobility prediction problem is defined as guessing a mobile node's next access point as it moves through a wireless network. Those predictions help take proactive measures in order to guarantee a ... [more ▼]

The mobility prediction problem is defined as guessing a mobile node's next access point as it moves through a wireless network. Those predictions help take proactive measures in order to guarantee a given quality of service. Prediction agents can be divided into two main categories: agents related to a specific terminal (responsible for anticipating its own movements) and those related to an access point (which predict the next access point of all the mobiles connected through it). This paper aims at comparing those two schemes using real traces of a large WiFi network. Several observations are made, such as the difficulties encountered to get a reliable trace of mobiles motion, the unexpectedly small difference between both methods in terms of accuracy, and the inadequacy of commonly admitted hypotheses (such as the different motion behaviours between the week-end and the rest of the week). [less ▲]

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See detailAp stars periodicity (Catalano+ 1997)
Catalano, F. A.; Renson, Pierre ULg

in VizieR Online Data Catalog (1996), 412

New data on the periods of Ap stars with references are presented (Table 1). 21 further stars are introduced for which a periodic variability has recently been discovered or for which it was known before ... [more ▼]

New data on the periods of Ap stars with references are presented (Table 1). 21 further stars are introduced for which a periodic variability has recently been discovered or for which it was known before but it was not reported in previous issues of this catalogue. For many stars also present in previous issues of the catalogue new determinations of the periods are given. Recently attributed variable star names are also quoted. Note: this catalog is included in <III/199> (2 data files). [less ▲]

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See detailAp stars periodicity (Catalano+, 2001)
Renson, Pierre ULg; Catalano, F. A.

Diverse speeche and writing (2001)

New data on the periods of Ap stars with references are presented. 161 further stars are introduced for which a periodic variability has recently been discovered or it was known before but it was not ... [more ▼]

New data on the periods of Ap stars with references are presented. 161 further stars are introduced for which a periodic variability has recently been discovered or it was known before but it was not reported in previous issues of this catalogue. For many stars also present in previous issues of the catalogue new determinations of the periods are given. Recently attributed variable star names are also quoted. (3 data files). [less ▲]

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See detailThe AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication.
Colin, Laurence; Vandenhoudt, Nathalie; de Walque, Stephane et al

in PLoS ONE (2011), 6(4), 19084

Our laboratory has previously identified an important intragenic region in the human immunodeficiency virus type 1 (HIV-1) genome, whose complete functional unit is composed of the 5103 fragment, the ... [more ▼]

Our laboratory has previously identified an important intragenic region in the human immunodeficiency virus type 1 (HIV-1) genome, whose complete functional unit is composed of the 5103 fragment, the DNaseI-hypersensitive site HS7 and the 5105 fragment. These fragments (5103 and 5105) both exhibit a phorbol 12-myristate 13-acetate (PMA)-inducible enhancer activity on the herpes simplex virus thymidine kinase promoter. Here, we characterized the three previously identified AP-1 binding sites of fragment 5103 by showing the PMA-inducible in vitro binding and in vivo recruitment of c-Fos, JunB and JunD to this fragment located at the end of the pol gene. Functional analyses demonstrated that the intragenic AP-1 binding sites are fully responsible for the PMA-dependent enhancer activity of fragment 5103. Moreover, infection of T-lymphoid Jurkat and promonocytic U937 cells with wild-type and mutant viruses demonstrated that mutations of the intragenic AP-1 sites individually or in combination altered HIV-1 replication. Importantly, mutations of the three intragenic AP-1 sites led to a decreased in vivo recruitment of RNA polymerase II to the viral promoter, strongly supporting that the deleterious effect of these mutations on viral replication occurs, at least partly, at the transcriptional level. Single-round infections of monocyte-derived macrophages confirmed the importance of intragenic AP-1 sites for HIV-1 infectivity. [less ▲]

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See detailAPA@ULg : les normes de l'A.P.A. (American Psychological Association)
Thirion, Paul ULg; Durieux, Nancy ULg

Learning material (2012)

Site destiné à expliquer les principales règles de l'American Psychological Association (APA) en matière de citations, de présentation de la liste des références et de présentation des tableaux et figures ... [more ▼]

Site destiné à expliquer les principales règles de l'American Psychological Association (APA) en matière de citations, de présentation de la liste des références et de présentation des tableaux et figures dans un document scientifique. Le site comporte une série d'exemples et quelques adaptations au contexte francophone. [less ▲]

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See detailApamin increases NMDA-induced burst-firing of rat mesencephalic dopamine neurons.
Seutin, Vincent ULg; Johnson, S. W.; North, R. A.

in Brain Research (1993), 630(1-2), 341-4

Intracellular recordings made in vitro from rat midbrain dopamine neurons showed that apamin (100 nM) did not alter the regular spontaneous firing of the neurons, but it increased the occurrence of bursts ... [more ▼]

Intracellular recordings made in vitro from rat midbrain dopamine neurons showed that apamin (100 nM) did not alter the regular spontaneous firing of the neurons, but it increased the occurrence of bursts of action potentials in N-methyl-D-aspartate. Apamin appeared to facilitate burst-firing induced by NMDA because, by blocking an outward calcium-activated potassium current, it increased the depolarizing action of NMDA. [less ▲]

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See detailL’apathie dans la Maladie d’Alzheimer: pourquoi et comment maintenir les patients aussi actifs que possible?
Adam, Stéphane ULg

Conference given outside the academic context (2011)

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See detailApathy in aging: Are lack of interest and lack of initiative dissociable?
Esposito, Fabienne; Rochat, Lucien; Juillerat Van der Linden, Anne-Claude et al

in Archives of Gerontology & Geriatrics (2014), 58

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See detailApatite-(CaOH) in the fossil bat guano deposit from the "dry" Cioclovina Cave, Şureanu Mountains, Romania
Dumitras, D.; Marincea, S.; Bilal, E. et al

in Canadian Mineralogist (2008), 46

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See detailApatridie, Etat-nation et démocratie lus par Arendt et ses héritiers.
Petteni, Oriane ULg

in Interpretationes (2014), 3(1), 85-109

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