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See detailAntiangiogenic peptides
Martial, Joseph ULiege; Struman, Ingrid ULiege; Nguyen, Ngoc-Quynh-Nhu ULiege et al

Patent (2007)

The present invention refers to antiangiogenic peptides, especially to tilted peptides having antiangiogenic properties and peptides from the prolactin/growth hormone familiy having antiangiogenic ... [more ▼]

The present invention refers to antiangiogenic peptides, especially to tilted peptides having antiangiogenic properties and peptides from the prolactin/growth hormone familiy having antiangiogenic properties. [less ▲]

Detailed reference viewed: 21 (2 ULiège)
See detailAntiangiogenic peptides
Martial, Joseph ULiege; Struman, Ingrid ULiege; Nguyen, Ngoc-Quynh-Nhu ULiege et al

Patent (2008)

The present invention refers to a pharmaceutical composition comprising an isolated antiangiogenic peptide or a recombinant protein comprising the antiangiogenic peptide, wherein the peptide is between 11 ... [more ▼]

The present invention refers to a pharmaceutical composition comprising an isolated antiangiogenic peptide or a recombinant protein comprising the antiangiogenic peptide, wherein the peptide is between 11 and 40 amino acids in length and having antiangiogenic activity, the peptide comprising the amino acid sequence: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14, wherein X1 is any amino acid residue comptabile with forming a helix; X2 is an amino acid redisue of : Leu, Ile, Val; X3 is an amino acid residue of: Arg, Lys, His, Ser, Thr; X4 is an amino acid residue of: Ile, Leu, Val; X5 is any amino acid residue compatible with forming a helix; X6 is an amino acid residue of: Leu, Ile, Val; X7 is an amino acid residue of: Leu, Ile, Val, Ser, Thr; X8 is any amino acid residue compatible with forming a helix; X9 is any amino acid residue compatible with forming a helix; X10 is an amino acid residue of: Gln, Glu, Asp, Arg, His, Lys, Asn; X11 is an amino acid residue of: Ser, Thr; X12 is an amino acid residue of: Trp, Tyr, Phe; X13 is an animo acid residue of Leu, Ile, Val, Asn, Gln; X14 is an amino acid residue of: Glu, Gln, Asp, Asn. [less ▲]

Detailed reference viewed: 63 (16 ULiège)
Peer Reviewed
See detailAntiapoptotic effect of GM-CSF activated STAT5 signaling pathway in chronic mastitis-affected cows : possible involvement in persistent accumulation of neutrophils in milk
Boutet, Philippe ULiege; Bureau, Fabrice ULiege; Gillet, Laurent ULiege et al

in Congress COST Action 844: “Apoptosis and programmed cell death : molecular mechanisms and applications in Biotechnology and Agriculture” (2004)

Detailed reference viewed: 32 (7 ULiège)
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See detailAntibacterial activity of 5-acylaminothiazole derivatives, synthetic drugs related to β-lactam antibiotics
Pirotte, Bernard ULiege; Delarge, Jacques; Coyette, Jacques ULiege et al

in Journal of Antibiotics (The) (1991), 44

Detailed reference viewed: 14 (2 ULiège)
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See detailAntibacterial activity of poly(vinyl alcohol)-b-poly(acrylonitrile) based micelles loaded with silver nanoparticles
Bryaskova, Rayna; Pencheva, Daniela; Kyulavska, Mariya et al

in Journal of Colloid & Interface Science (2010), 344(2), 424-448

A new amphiphilic poly(vinyl alcohol)-b-poly(acrylonitrile) (PVOH-b-PAN) copolymer obtained by selective hydrolysis of well-defined poly(vinyl acetate)-b-poly(acrylonitrile) copolymer synthesized by ... [more ▼]

A new amphiphilic poly(vinyl alcohol)-b-poly(acrylonitrile) (PVOH-b-PAN) copolymer obtained by selective hydrolysis of well-defined poly(vinyl acetate)-b-poly(acrylonitrile) copolymer synthesized by cobalt mediated radical polymerization was used for the preparation of PVOH-b-PAN based micelles with embedded silver nanoparticles. The successful formation of silver loaded micelles has been confirmed by UV–vis, DLS and TEM analysis and their antibacterial activity against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Pseudomonas aeruginosa (P. aeruginosa) and spore solution of Bacillus subtilis (B. subtilis) has been studied. PVOH-b-PAN based micelles with embedded silver nanoparticles showed a strong bactericidal effect against E. coli, S. aureus and P. aeruginosa and the minimum bactericidal concentration for each system (MBC) has been determined. [less ▲]

Detailed reference viewed: 150 (7 ULiège)
See detailAntibacterial coatings of copolymers based on poly(ionic liquids)
Weiss-Maurin, Mathilde ULiege; Detrembleur, Christophe ULiege; Taton, Daniel

Conference (2015, March 16)

Detailed reference viewed: 23 (4 ULiège)
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See detailAntibacterial polyelectrolyte micelles for coating stainless steel
Falentin, Céline ULiege; Faure, Emilie ULiege; Svaldo Lanero, Tiziana ULiege et al

in Langmuir (2012), 28(18), 7233-7241

In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged ... [more ▼]

In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged polyelectrolytes micelles doped with silver based nanoparticles with a polyanion. The micelles are formed by electrostatic interaction between two oppositely charged polymers, a polycation bearing 3,4-dihydroxyphenylalanine units (DOPA, a major component of natural adhesives) and a polyanion (poly(styrene sulfonate), PSS) without using any block copolymer. DOPA units are exploited for their well-known ability to anchor to stainless steel and to form and stabilize biocidal silver nanoparticles (Ag0). The chlorine counter-anion of the polycation forms and stabilizes biocidal silver chloride nanoparticles (AgCl). We demonstrate that two layers of micelles (alternated by PSS) doped by silver particles are enough to impart to the surface a strong antibacterial activity against Gram-negative E. coli. Moreover, micelles that are reservoirs of biocidal Ag+ can be easily reactivated after depletion. This novel water-based approach is convenient, simple and attractive for industrial applications. [less ▲]

Detailed reference viewed: 176 (17 ULiège)
See detailL'antibiorésistance chez l'animal et ses conséquences
Mainil, Jacques ULiege

Scientific conference (1999, May)

Detailed reference viewed: 17 (0 ULiège)
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See detailL'antibiothérapie en néonatalogie: mise-au-point
Langhendries, JP; Kalenga, Masendu ULiege; Battisti, Oreste ULiege et al

in Journal du Pédiatre Belge (2000), 2

Detailed reference viewed: 91 (11 ULiège)
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See detailAntibiothérapie topique et infections cutanées
Henry, Frédérique ULiege; Nikkels, Arjen ULiege; Pierard-Franchimont, Claudine ULiege et al

in Revue Médicale de Liège (1996), 51(2), 160-162

Les infections cutanées bactériennes, qui restent souvent limitées en extension, méritent un traitement local. Dans cette indication, l'antibiothérapie topique est toujours d'actualité. Le choix du ... [more ▼]

Les infections cutanées bactériennes, qui restent souvent limitées en extension, méritent un traitement local. Dans cette indication, l'antibiothérapie topique est toujours d'actualité. Le choix du médicament doit être guidé par son spectre d'activité. Les risques de développement d'une résistance bactérienne et d'une hypersensibilité allergique à l'antibiotique ou à sa base galénique doivent également être pris en considération. [less ▲]

Detailed reference viewed: 33 (2 ULiège)
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See detailAntibiotherapy in bovine mastitis – Drugs or Therapeutics?
Theron, Léonard ULiege; Hanzen, Christian ULiege

Conference given outside the academic context (2012)

The 21st century is rich in mutations regarding veterinary medicine; society has never been so far from farm animal practices in industrialized countries, and so demanding in developing nations for a ... [more ▼]

The 21st century is rich in mutations regarding veterinary medicine; society has never been so far from farm animal practices in industrialized countries, and so demanding in developing nations for a continuous milk and meat production. Meanwhile, even this great distance in northern nations between agriculture and society, our work has never been so much analyzed for its potential risk on human health and production quality. As health is now globalized, following trade and science, exchange could be the source of several pathological emergences. Focusing on animal health, our responsibility toward “larga manu” use of antibiotics has been identified and criticized. This situation is also happening in a time where, nevertheless our industrialization of agricultural production, ancillary exams are still expensive, and most of the time non valuable regarding a common cattle practice time schedule. So yes, we are mainly still experiencing empirical use of antibiotics like our pairs did, back several decades before. Yet, there exists nowadays many tools to analyze whether our practice could be considered as harmful to humanity survival and good use of priority antibiotics. We therefore have to reconsider our practice of Antibiotherapy, regarding these new challenges and find new ways for medical management of infectious diseases. [less ▲]

Detailed reference viewed: 124 (7 ULiège)
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See detailAntibiotherapy in pet rodents and rabbits: a preliminary analysis of practitioners’ habits
Marlier, Didier ULiege

in Proceedings of the European College of Zoological Medicine Symposium (2016, April)

Detailed reference viewed: 26 (12 ULiège)
See detailAntibiothérpaie chez le chien : choix raisonné et raisonnable
Mainil, Jacques ULiege

Scientific conference (2015, December)

Detailed reference viewed: 21 (0 ULiège)
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See detailAntibiotic action on enzymes involved in peptidoglycan synthesis
Ghuysen, Jean-Marie ULiege; Perkins, HR; Frere, JM et al

in Sund, Horst (Ed.) Protein-ligand interactions : proceedings of a symposium held at the University of Konstanz (1974)

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See detailThe antibiotic ceftazidime is a singlet oxygen quencher as demonstrated by ultra-weak chemiluminescence and by inhibition of AAP consumption.
Deby, Ginette ULiege; Deby, C.; Mouithys-Mickalad, Ange ULiege et al

in Biochimica et Biophysica Acta (1998), 1379(1), 61-8

We demonstrated that the cephalosporin antibiotic ceftazidime (CAZ) deactivated singlet oxygen (1O2). We then studied the mechanisms of the CAZ effects on the ultra weak chemiluminescence (uwCL ... [more ▼]

We demonstrated that the cephalosporin antibiotic ceftazidime (CAZ) deactivated singlet oxygen (1O2). We then studied the mechanisms of the CAZ effects on the ultra weak chemiluminescence (uwCL) associated with the energy decay of 1O2 generated by the Mallet reaction (H2O2 + HOCl --> HCl + H2O + 1O2), and on the anthracene-9,10-dipropionic acid (AAP) consumption by 1O2 generated by irradiation of Rose Bengal (RB). The uwCL generated by the Mallet reaction was amplified (6.2 times) by CAZ. The use of red and blue filters, which absorb radiation below 610 nm and between 470 and 700 nm respectively, demonstrated that CAZ increased the uwCL by a radiation emission at wavelengths shorter than the 633 and 704 nm wavelength emissions of 1O2. CAZ was excited by scavenging the energy excess of 1O2, which so returned to its fundamental state, while CAZ deactivated with light emission between 430-480 nm. CAZ also inhibited in a dose-dependent manner the consumption of AAP by 1O2 generated by the irradiation of RB. The protection of AAP by 5 x 10(-3) M CAZ was equivalent to that of 10(-3) M histidine and 3 X 10(-6) M sodium azide. This process of 1O2 deactivation will be useful in diseases characterized by an excessive PMN activation with a release of activated oxygen species. [less ▲]

Detailed reference viewed: 106 (18 ULiège)
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See detailAntibiotic compounds from Bacillus: why are they so amazing
Fickers, Patrick ULiege

in American Journal of Biochemistry & Biotechnology (2012), (8), 38-43

Detailed reference viewed: 36 (0 ULiège)
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See detailAntibiotic compounds from Bacillus: why are they so amazing?
Fickers, Patrick ULiege

Conference (2014, April)

Detailed reference viewed: 12 (0 ULiège)